{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T15:56:23Z","timestamp":1764258983018,"version":"build-2065373602"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T00:00:00Z","timestamp":1615420800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.ijid.2021.03.039","type":"journal-article","created":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T13:20:09Z","timestamp":1616073609000},"page":"190-197","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Two cases of hand, foot and mouth disease caused by enterovirus A71 after vaccination"],"prefix":"10.1016","volume":"108","author":[{"given":"Jiaolian","family":"Tang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9659-5533","authenticated-orcid":false,"given":"Zhilei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hailing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingyi","family":"Du","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaodan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lingmei","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin","family":"Rao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinghui","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meifeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ru","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiangming","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8467-8446","authenticated-orcid":false,"given":"Hongchao","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijid.2021.03.039_bib0005","doi-asserted-by":"crossref","first-page":"e0188640","DOI":"10.1371\/journal.pone.0188640","article-title":"Epidemiological and genetic characteristics of EV71 in hand, foot, and mouth disease in Guangxi, southern China, from 2010 to 2015","volume":"12","author":"Chen","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.ijid.2021.03.039_bib0010","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.virusres.2006.12.005","article-title":"Identification of neutralizing linear epitopes from the VP1 capsid protein of enterovirus 71 using synthetic peptides","volume":"125","author":"Foo","year":"2007","journal-title":"Virus Res"},{"key":"10.1016\/j.ijid.2021.03.039_bib0015","doi-asserted-by":"crossref","first-page":"e00682","DOI":"10.1128\/JVI.00682-18","article-title":"VP1 amino acid residue 145 of enterovirus 71 is a key residue for its receptor attachment and resistance to neutralizing antibody during cynomolgus monkey infection","volume":"92","author":"Fujii","year":"2018","journal-title":"J Virol"},{"key":"10.1016\/j.ijid.2021.03.039_bib0020","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s12250-019-00169-2","article-title":"National epidemiology and evolutionary history of four hand, foot and mouth disease-related enteroviruses in China from 2008 to 2016","volume":"35","author":"Fu","year":"2020","journal-title":"Virol Sin"},{"key":"10.1016\/j.ijid.2021.03.039_bib0025","doi-asserted-by":"crossref","first-page":"3088","DOI":"10.1093\/cid\/ciz1188","article-title":"Early evidence of inactivated enterovirus 71 vaccine impact against hand, foot, and mouth disease in a major center of ongoing transmission in China, 2011\u20132018: a longitudinal surveillance study","volume":"71","author":"Head","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijid.2021.03.039_bib0030","doi-asserted-by":"crossref","first-page":"6596","DOI":"10.1016\/j.vaccine.2015.10.104","article-title":"A new EV71 VP3 epitope in norovirus P particle vector displays neutralizing activity and protection in vivo in mice","volume":"33","author":"Jiang","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.ijid.2021.03.039_bib0035","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005033","article-title":"The role of VP1 amino acid residue 145 of enterovirus 71 in viral fitness and pathogenesis in a cynomolgus monkey model","volume":"11","author":"Kataoka","year":"2015","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.ijid.2021.03.039_bib0040","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1056\/NEJMoa1303224","article-title":"An inactivated enterovirus 71 vaccine in healthy children","volume":"370","author":"Li","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijid.2021.03.039_bib0045","doi-asserted-by":"crossref","first-page":"e27","DOI":"10.1038\/emi.2014.29","article-title":"EV71 vaccines: a milestone in the history of global vaccine development","volume":"3","author":"Lu","year":"2014","journal-title":"Emerg Microbes Infect"},{"key":"10.1016\/j.ijid.2021.03.039_bib0050","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1586\/14760584.2016.1138862","article-title":"EV71 vaccine, a new tool to control outbreaks of hand, foot and mouth disease (HFMD)","volume":"15","author":"Mao","year":"2016","journal-title":"Expert Rev Vaccines"},{"key":"10.1016\/j.ijid.2021.03.039_bib0055","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.jcv.2015.08.017","article-title":"A severe case of co-infection with enterovirus 71 and vaccine-derived poliovirus type II","volume":"72","author":"Ma","year":"2015","journal-title":"J Clin Virol"},{"key":"10.1016\/j.ijid.2021.03.039_bib0060","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1574-6976.2002.tb00601.x","article-title":"An overview of the evolution of enterovirus 71 and its clinical and public health significance","volume":"26","author":"McMinn","year":"2002","journal-title":"FEMS Microbiol Rev"},{"issue":"Suppl. 2","key":"10.1016\/j.ijid.2021.03.039_bib0065","doi-asserted-by":"crossref","first-page":"S387","DOI":"10.1093\/clinids\/6.Supplement_2.S387","article-title":"Enterovirus type 71 infections: a varied clinical pattern sometimes mimicking paralytic poliomyelitis","volume":"6","author":"Melnick","year":"1984","journal-title":"Rev Infect Dis"},{"key":"10.1016\/j.ijid.2021.03.039_bib0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004562","article-title":"Cyclical patterns of hand, foot and mouth disease caused by enterovirus A71 in Malaysia","volume":"10","author":"NikNadia","year":"2016","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.ijid.2021.03.039_bib0075","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.ijid.2018.12.020","article-title":"Longitudinal study on enterovirus A71 and coxsackievirus A16 genotype\/subgenotype replacements in hand, foot and mouth disease patients in Thailand, 2000\u20132017","volume":"80","author":"Noisumdaeng","year":"2019","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.ijid.2021.03.039_bib0080","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/S1474-4422(10)70209-X","article-title":"Clinical features, diagnosis, and management of enterovirus 71","volume":"9","author":"Ooi","year":"2010","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.ijid.2021.03.039_bib0085","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1126\/science.1218713","article-title":"Crystal structure of human enterovirus 71","volume":"336","author":"Plevka","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.ijid.2021.03.039_bib0090","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1128\/JCM.02369-09","article-title":"Clinical and etiological characteristics of enterovirus 71-related diseases during a recent 2-year period in Korea","volume":"48","author":"Ryu","year":"2010","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijid.2021.03.039_bib0095","doi-asserted-by":"crossref","DOI":"10.1098\/rsif.2018.0507","article-title":"Epidemic dynamics, interactions and predictability of enteroviruses associated with hand, foot and mouth disease in Japan","volume":"15","author":"Takahashi","year":"2018","journal-title":"J R Soc Interface"},{"key":"10.1016\/j.ijid.2021.03.039_bib0100","doi-asserted-by":"crossref","first-page":"e25662","DOI":"10.1371\/journal.pone.0025662","article-title":"The persistent circulation of enterovirus 71 in People\u2019s Republic of China: causing emerging nationwide epidemics since 2008","volume":"6","author":"Tan","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ijid.2021.03.039_bib0105","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.3201\/eid1311.070632","article-title":"Epidemiologic and virologic investigation of hand, foot, and mouth disease, southern Vietnam, 2005","volume":"13","author":"Van Tu","year":"2007","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.ijid.2021.03.039_bib0110","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1093\/infdis\/jiw502","article-title":"2-year efficacy, immunogenicity, and safety of Vigoo enterovirus 71 vaccine in healthy Chinese children: a randomized open-label study","volume":"215","author":"Wei","year":"2017","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ijid.2021.03.039_bib0115","doi-asserted-by":"crossref","first-page":"e1076","DOI":"10.1016\/j.ijid.2010.07.006","article-title":"The largest outbreak of hand; foot and mouth disease in Singapore in 2008: the role of enterovirus 71 and coxsackievirus A strains","volume":"14","author":"Wu","year":"2010","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.ijid.2021.03.039_bib0120","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/1743-422X-7-94","article-title":"An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of hand foot and mouth disease in Fuyang city of China","volume":"7","author":"Zhang","year":"2010","journal-title":"Virol J"},{"key":"10.1016\/j.ijid.2021.03.039_bib0125","article-title":"Complete genome analysis of the C4 subgenotype strains of enterovirus 71: predominant recombination C4 viruses persistently circulating in China for 14 years","volume":"8","author":"Zhang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ijid.2021.03.039_bib0130","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1016\/S0140-6736(13)61049-1","article-title":"Efficacy, safety, and immunology of an inactivated alum-adjuvant enterovirus 71 vaccine in children in China: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial","volume":"381","author":"Zhu","year":"2013","journal-title":"Lancet"},{"key":"10.1016\/j.ijid.2021.03.039_bib0135","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1056\/NEJMoa1304923","article-title":"Efficacy, safety, and immunogenicity of an enterovirus 71 vaccine in China","volume":"370","author":"Zhu","year":"2014","journal-title":"N Engl J Med"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971221002575?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971221002575?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T07:58:34Z","timestamp":1761119914000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971221002575"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":27,"alternative-id":["S1201971221002575"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2021.03.039","relation":{},"ISSN":["1201-9712"],"issn-type":[{"type":"print","value":"1201-9712"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Two cases of hand, foot and mouth disease caused by enterovirus A71 after vaccination","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2021.03.039","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}]}}