{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T20:42:28Z","timestamp":1788381748072,"version":"build-2803163510"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,3,21]],"date-time":"2022-03-21T00:00:00Z","timestamp":1647820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.ijid.2022.03.035","type":"journal-article","created":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T21:53:19Z","timestamp":1648158799000},"page":"S63-S68","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"S1","title":["Xpert MTB\/RIF on urine samples to increase diagnosis of TB in people living with HIV in Guinea-Bissau"],"prefix":"10.1016","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4123-0083","authenticated-orcid":false,"given":"Alexander","family":"Dutschke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ditte","family":"Steiniche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanne","family":"Jespersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joao Paulo","family":"Nanque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Candida","family":"Medina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9636-4519","authenticated-orcid":false,"given":"Bo Langhoff","family":"H\u00f8nge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2534-2942","authenticated-orcid":false,"given":"Christian","family":"Wejse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"suppl_4","key":"10.1016\/j.ijid.2022.03.035_bib0001","doi-asserted-by":"crossref","first-page":"S1130","DOI":"10.1093\/infdis\/jir450","article-title":"Adjunctive Tests for Diagnosis of Tuberculosis: Serology, ELISPOT for Site-Specific Lymphocytes, Urinary Lipoarabinomannan, String Test, and Fine Needle Aspiration","volume":"204","author":"Achkar","year":"2011","journal-title":"The Journal of Infectious Diseases"},{"key":"10.1016\/j.ijid.2022.03.035_bib0002","doi-asserted-by":"crossref","first-page":"S78","DOI":"10.1016\/j.ijid.2020.03.012","article-title":"A clinical score has utility in tuberculosis case-finding among patients with HIV: A feasibility study from Bissau","volume":"92s","author":"Aunsborg","year":"2020","journal-title":"Int J Infect Dis"},{"issue":"10","key":"10.1016\/j.ijid.2022.03.035_bib0003","article-title":"Lateral flow urine lipoarabinomannan assay for detecting active tuberculosis in people living with HIV","volume":"10","author":"Bjerrum","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"issue":"9776","key":"10.1016\/j.ijid.2022.03.035_bib0004","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1016\/S0140-6736(11)60438-8","article-title":"Feasibility, diagnostic accuracy, and effectiveness of decentralised use of the Xpert MTB\/RIF test for diagnosis of tuberculosis and multidrug resistance: a multicentre implementation study","volume":"377","author":"Boehme","year":"2011","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.ijid.2022.03.035_bib0005","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1093\/cid\/cis409","article-title":"Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study","volume":"55","author":"Crump","year":"2012","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.ijid.2022.03.035_bib0006","first-page":"52","article-title":"Chest radiograph reading and recording system: evaluation for tuberculosis screening in patients with advanced HIV","volume":"14","author":"Dawson","year":"2010","journal-title":"Int J Tuberc Lung Dis"},{"issue":"4","key":"10.1016\/j.ijid.2022.03.035_bib0007","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1007\/s15010-020-01574-6","article-title":"Life expectancy of HIV-infected patients followed at the largest hospital in Guinea-Bissau is one-fourth of life expectancy of the background population","volume":"49","author":"Engell-S\u00f8rensen","year":"2021","journal-title":"Infection"},{"issue":"9578","key":"10.1016\/j.ijid.2022.03.035_bib0008","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1016\/S0140-6736(07)60284-0","article-title":"Diagnosis of smear-negative pulmonary tuberculosis in people with HIV infection or AIDS in resource-constrained settings: informing urgent policy changes","volume":"369","author":"Getahun","year":"2007","journal-title":"Lancet"},{"issue":"15","key":"10.1016\/j.ijid.2022.03.035_bib0009","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1097\/QAD.0000000000000802","article-title":"Prevalence of tuberculosis in post-mortem studies of HIV-infected adults and children in resource-limited settings: a systematic review and meta-analysis","volume":"29","author":"Gupta","year":"2015","journal-title":"Aids"},{"issue":"1","key":"10.1016\/j.ijid.2022.03.035_bib0010","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/QAI.0b013e3182a97b81","article-title":"Performance of 3 rapid tests for discrimination between HIV-1 and HIV-2 in Guinea-Bissau, West Africa","volume":"65","author":"H\u00f8nge","year":"2014","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"10","key":"10.1016\/j.ijid.2022.03.035_bib0011","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2013-003499","article-title":"Loss to follow-up occurs at all stages in the diagnostic and follow-up period among HIV-infected patients in Guinea-Bissau: a 7-year retrospective cohort study","volume":"3","author":"H\u00f8nge","year":"2013","journal-title":"BMJ Open"},{"issue":"1","key":"10.1016\/j.ijid.2022.03.035_bib0012","doi-asserted-by":"crossref","first-page":"20243","DOI":"10.7448\/IAS.18.1.20243","article-title":"Lack of awareness of treatment failure among HIV-1-infected patients in Guinea-Bissau - a retrospective cohort study","volume":"18","author":"Jespersen","year":"2015","journal-title":"J Int AIDS Soc"},{"issue":"3","key":"10.1016\/j.ijid.2022.03.035_bib0013","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1093\/ije\/dyu201","article-title":"Cohort Profile: The Bissau HIV Cohort-a cohort of HIV-1, HIV-2 and co-infected patients","volume":"44","author":"Jespersen","year":"2015","journal-title":"Int J Epidemiol"},{"issue":"1","key":"10.1016\/j.ijid.2022.03.035_bib0014","doi-asserted-by":"crossref","first-page":"10931","DOI":"10.1038\/s41598-017-09895-7","article-title":"Disseminated tuberculosis among hospitalised HIV patients in South Africa: a common condition that can be rapidly diagnosed using urine-based assays","volume":"7","author":"Kerkhoff","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijid.2022.03.035_bib0015","article-title":"The spectrum of clinical and pathological manifestations of AIDS in a consecutive series of 236 autopsied cases in mumbai, India","volume":"2011","author":"Lanjewar","year":"2011","journal-title":"Patholog Res Int"},{"issue":"1","key":"10.1016\/j.ijid.2022.03.035_bib0016","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s12916-017-0822-8","article-title":"Diagnostic accuracy, incremental yield and prognostic value of Determine TB-LAM for routine diagnostic testing for tuberculosis in HIV-infected patients requiring acute hospital admission in South Africa: a prospective cohort","volume":"15","author":"Lawn","year":"2017","journal-title":"BMC Med"},{"issue":"1","key":"10.1016\/j.ijid.2022.03.035_bib0017","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1186\/s12916-015-0432-2","article-title":"). Rapid microbiological screening for tuberculosis in HIV-positive patients on the first day of acute hospital admission by systematic testing of urine samples using Xpert MTB\/RIF: a prospective cohort in South Africa","volume":"13","author":"Lawn","year":"2015","journal-title":"BMC Medicine"},{"issue":"3","key":"10.1016\/j.ijid.2022.03.035_bib0018","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/QAI.0b013e318258c6af","article-title":"High diagnostic yield of tuberculosis from screening urine samples from HIV-infected patients with advanced immunodeficiency using the Xpert MTB\/RIF assay","volume":"60","author":"Lawn","year":"2012","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"1","key":"10.1016\/j.ijid.2022.03.035_bib0019","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1186\/1741-7015-11-231","article-title":"HIV-associated tuberculosis: relationship between disease severity and the sensitivity of new sputum-based and urine-based diagnostic assays","volume":"11","author":"Lawn","year":"2013","journal-title":"BMC Medicine"},{"issue":"Suppl 4","key":"10.1016\/j.ijid.2022.03.035_bib0020","doi-asserted-by":"crossref","first-page":"S1159","DOI":"10.1093\/infdis\/jir411","article-title":"Tuberculosis in antiretroviral treatment services in resource-limited settings: addressing the challenges of screening and diagnosis","volume":"204","author":"Lawn","year":"2011","journal-title":"J Infect Dis"},{"issue":"9","key":"10.1016\/j.ijid.2022.03.035_bib0021","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1097\/QAD.0000000000001827","article-title":"HIV-2 continues to decrease, whereas HIV-1 is stabilizing in Guinea-Bissau","volume":"32","author":"Olesen","year":"2018","journal-title":"Aids"},{"issue":"7","key":"10.1016\/j.ijid.2022.03.035_bib0022","doi-asserted-by":"crossref","first-page":"e39966","DOI":"10.1371\/journal.pone.0039966","article-title":"The diagnostic accuracy of urine-based Xpert MTB\/RIF in HIV-infected hospitalized patients who are smear-negative or sputum scarce","volume":"7","author":"Peter","year":"2012","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.ijid.2022.03.035_bib0023","doi-asserted-by":"crossref","first-page":"825","DOI":"10.3109\/00365548.2013.826876","article-title":"TBscore II: refining and validating a simple clinical score for treatment monitoring of patients with pulmonary tuberculosis","volume":"45","author":"Rudolf","year":"2013","journal-title":"Scand J Infect Dis"},{"issue":"1","key":"10.1016\/j.ijid.2022.03.035_bib0024","doi-asserted-by":"crossref","first-page":"978","DOI":"10.4102\/sajhivmed.v20i1.978","article-title":"False rifampicin resistant results using Xpert MTB\/RIF on urine samples in hospitalised HIV-infected patients","volume":"20","author":"Schutz","year":"2019","journal-title":"South Afr J HIV Med"},{"issue":"Suppl 3","key":"10.1016\/j.ijid.2022.03.035_bib0025","doi-asserted-by":"crossref","first-page":"S223","DOI":"10.1086\/651495","article-title":"HIV infection-related tuberculosis: clinical manifestations and treatment","volume":"50","author":"Sterling","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijid.2022.03.035_bib0026","unstructured":"SSI2018. SSI, Tuberkulosebek\u00e6mpelse i Danmark et nationalt tuberkuloseprogram 2018, TB guideline, 2018, https:\/\/www.ssi.dk\/-\/media\/arkiv\/indhold\/dk-dansk\/sygdomsleksikon\/tb-guideline_dk_2018.pdf?la=da (accessed 06.08.2021)."},{"key":"10.1016\/j.ijid.2022.03.035_bib0027","unstructured":"UNAIDS 2019a. Tuberculosis and HIV- Progress towards the 2020 target, https:\/\/www.unaids.org\/en\/resources\/documents\/2019\/tuberculosis-and-hiv-progress-towards-the-2020-target (accessed 20.07.21)."},{"key":"10.1016\/j.ijid.2022.03.035_bib0028","unstructured":"UNAIDS 2019b. Guinea-Bissau, https:\/\/www.unaids.org\/en\/regionscountries\/countries\/guinea-bissau (accessed 15.07.2021)"},{"key":"10.1016\/j.ijid.2022.03.035_bib0029","unstructured":"UNAIDS 2020. Global HIV and AIDS statistics - 2020 fact sheet https:\/\/www.unaids.org\/sites\/default\/files\/media_asset\/UNAIDS_FactSheet_en.pdf. (accessed 01.07.2021)."},{"key":"10.1016\/j.ijid.2022.03.035_bib0030","unstructured":"WHO 2010. Guidelines for intensified tuberculosis case-finding and isoniazid preventive therapy for people living with HIV in resource-constrained settings, http:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/44472\/9789241500708_eng.pdf;jsessionid=9A04B22D2BF378C9987F90B1FE7823AB?sequence=1, WHO Global TB Programme, 2010 (accessed 05.07.21)."},{"key":"10.1016\/j.ijid.2022.03.035_bib0031","unstructured":"WHO 2013a. Systematic screening for active tuberculosis, Principles and recommendation, https:\/\/www.who.int\/tb\/publications\/Final_TB_Screening_guidelines.pdf, WHO, 2013 (accessed 15.07.21)."},{"key":"10.1016\/j.ijid.2022.03.035_bib0032","unstructured":"WHO 2020. Global Tuberculosis Report 2020, World Health Organization. https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/336069\/9789240013131-eng.pdf (accessed 15.07.21)."}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971222001746?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971222001746?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T08:10:39Z","timestamp":1761120639000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971222001746"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":32,"alternative-id":["S1201971222001746"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2022.03.035","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Xpert MTB\/RIF on urine samples to increase diagnosis of TB in people living with HIV in Guinea-Bissau","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2022.03.035","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}]}}