{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T10:13:26Z","timestamp":1776334406252,"version":"3.51.2"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T00:00:00Z","timestamp":1700179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.ijid.2023.11.021","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T07:13:54Z","timestamp":1701069234000},"page":"13-20","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Previous immune checkpoint inhibitor therapy is associated with decreased COVID-19-related hospitalizations and complications in patients with cancer: Results of a propensity-matched analysis of the OnCovid registry"],"prefix":"10.1016","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5790-9288","authenticated-orcid":false,"given":"Anahita","family":"Mostaghim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5149-5467","authenticated-orcid":false,"given":"Samuel","family":"Minkove","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9838-1950","authenticated-orcid":false,"given":"Juan","family":"Aguilar-Company","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Ruiz-Camps","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simeon","family":"Eremiev-Eremiev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4751-3810","authenticated-orcid":false,"given":"Gino M.","family":"Dettorre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Fox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Tondini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1945-3512","authenticated-orcid":false,"given":"Joan","family":"Brunet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4011-9474","authenticated-orcid":false,"given":"MCarmen","family":"Carmona-Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1797-5296","authenticated-orcid":false,"given":"Matteo","family":"Lambertini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Bower","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Newsom-Davis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Sharkey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessia Dalla","family":"Pria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maura","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Plaja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramon","family":"Salazar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Sureda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleix","family":"Prat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3102-3534","authenticated-orcid":false,"given":"Vasiliki","family":"Michalarea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mieke","family":"Van Hemelrijck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ailsa","family":"Sita-Lumsden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexia","family":"Bertuzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenza","family":"Rimassa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Rossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1946-4967","authenticated-orcid":false,"given":"Gianpiero","family":"Rizzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Pedrazzoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7427-9142","authenticated-orcid":false,"given":"Alvin JX","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1356-959X","authenticated-orcid":false,"given":"Cian","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Belessiotis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos","family":"Diamantis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uma","family":"Mukherjee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fanny","family":"Pommeret","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0052-3103","authenticated-orcid":false,"given":"Annabelle","family":"Stoclin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clara","family":"Martinez-Vila","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Bruna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4681-0151","authenticated-orcid":false,"given":"Gianluca","family":"Gaidano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"D'Avanzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Gennari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janhavi","family":"Athale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Eichacker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David J.","family":"Pinato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7446-1702","authenticated-orcid":false,"given":"Parizad","family":"Torabi-Parizi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1209-5735","authenticated-orcid":false,"given":"Alessio","family":"Cortellini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijid.2023.11.021_bib0001","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.ccell.2015.03.001","article-title":"Immune checkpoint blockade: a common denominator approach to cancer therapy","volume":"27","author":"Topalian","year":"2015","journal-title":"Cancer Cell"},{"key":"10.1016\/j.ijid.2023.11.021_bib0002","doi-asserted-by":"crossref","first-page":"269","DOI":"10.2217\/imt-2020-0067","article-title":"Controversies about COVID-19 and anticancer treatment with immune checkpoint inhibitors","volume":"12","author":"Bersanelli","year":"2020","journal-title":"Immunotherapy"},{"key":"10.1016\/j.ijid.2023.11.021_bib0003","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1158\/2326-6066.CIR-21-0008","article-title":"At the crossroads: COVID-19 and immune-checkpoint blockade for cancer","volume":"9","author":"Garassino","year":"2021","journal-title":"Cancer Immunol Res"},{"key":"10.1016\/j.ijid.2023.11.021_bib0004","doi-asserted-by":"crossref","first-page":"351","DOI":"10.2217\/imt-2020-0077","article-title":"Do checkpoint inhibitors compromise the cancer patients' immunity and increase the vulnerability to COVID-19 infection?","volume":"12","author":"Kattan","year":"2020","journal-title":"Immunotherapy"},{"key":"10.1016\/j.ijid.2023.11.021_bib0005","doi-asserted-by":"crossref","first-page":"3383","DOI":"10.3390\/cancers12113383","article-title":"Cancer and immune checkpoint inhibitor treatment in the era of SARS-CoV-2 infection","volume":"12","author":"Gambichler","year":"2020","journal-title":"Cancers"},{"key":"10.1016\/j.ijid.2023.11.021_bib0006","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1084\/jem.20121015","article-title":"Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice","volume":"209","author":"Frebel","year":"2012","journal-title":"J Exp Med"},{"key":"10.1016\/j.ijid.2023.11.021_bib0007","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1093\/infdis\/jix191","article-title":"Clinical trial of the anti-PD-L1 antibody BMS-936559 in HIV-1 infected participants on suppressive antiretroviral therapy","volume":"215","author":"Gay","year":"2017","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ijid.2023.11.021_bib0008","doi-asserted-by":"crossref","first-page":"e2352","DOI":"10.1002\/rmv.2352","article-title":"Comprehensive adjusted outcome data are needed to assess the impact of immune checkpoint inhibitors in cancer patients with COVID-19: results of a systematic review and meta-analysis","volume":"32","author":"Minkove","year":"2022","journal-title":"Rev Med Virol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0009","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1200\/JCO.21.01074","article-title":"Outcomes of COVID-19 in patients with cancer: report from the national COVID cohort collaborative (N3C)","volume":"39","author":"Sharafeldin","year":"2021","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0010","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.0130","article-title":"Mortality among adults with cancer undergoing chemotherapy or immunotherapy and infected with COVID-19","volume":"5","author":"V\u00e1rnai","year":"2022","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.ijid.2023.11.021_bib0011","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1186\/s12885-022-09320-x","article-title":"The impact of anti-tumor approaches on the outcomes of cancer patients with COVID-19: a meta-analysis based on 52 cohorts incorporating 9231 participants","volume":"22","author":"Wu","year":"2022","journal-title":"BMC Cancer"},{"key":"10.1016\/j.ijid.2023.11.021_bib0012","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2022-005732","article-title":"Immune checkpoint inhibitor therapy and outcomes from SARS-CoV-2 infection in patients with cancer: a joint analysis of OnCovid and ESMO-CoCARE registries","volume":"10","author":"Cortellini","year":"2022","journal-title":"J Immunother Cancer"},{"key":"10.1016\/j.ijid.2023.11.021_bib0013","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ejca.2022.03.019","article-title":"Persistence of long-term COVID-19 sequelae in patients with cancer: an analysis from the OnCovid registry","volume":"170","author":"Cortellini","year":"2022","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ijid.2023.11.021_bib0014","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2020-002277","article-title":"Systemic pro-inflammatory response identifies patients with cancer with adverse outcomes from SARS-CoV-2 infection: the OnCovid inflammatory Score","volume":"9","author":"Dettorre","year":"2021","journal-title":"J Immunother Cancer"},{"key":"10.1016\/j.ijid.2023.11.021_bib0015","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1001\/jamaoncol.2021.6199","article-title":"Time-dependent COVID-19 mortality in patients with cancer: an updated analysis of the OnCovid Registry","volume":"8","author":"Pinato","year":"2022","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0016","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/S1470-2045(22)00273-X","article-title":"Outcomes of the SARS-CoV-2 omicron (B.1.1.529) variant outbreak among vaccinated and unvaccinated patients with cancer in Europe: results from the retrospective, multicentre, OnCovid registry study","volume":"23","author":"Pinato","year":"2022","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0017","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ejca.2022.04.036","article-title":"Vaccination against SARS-CoV-2 protects from morbidity, mortality and sequelae from COVID-19 in patients with cancer","volume":"171","author":"Pinato","year":"2022","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ijid.2023.11.021_bib0018","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1016\/S1470-2045(21)00573-8","article-title":"Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who recovered from SARS-CoV-2 infection: evidence from the OnCovid retrospective, multicentre registry study","volume":"22","author":"Pinato","year":"2021","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0019","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1158\/2159-8290.CD-20-0773","article-title":"Clinical portrait of the SARS-CoV-2 epidemic in European cancer patients","volume":"10","author":"Pinato","year":"2020","journal-title":"Cancer Discov"},{"key":"10.1016\/j.ijid.2023.11.021_bib0020","doi-asserted-by":"crossref","DOI":"10.1177\/17588359211053416","article-title":"COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry","volume":"13","author":"Garrig\u00f3s","year":"2021","journal-title":"Ther Adv Med Oncol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0021","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.ejca.2021.03.035","article-title":"Determinants of enhanced vulnerability to coronavirus disease 2019 in UK patients with cancer: a European study","volume":"150","author":"Pinato","year":"2021","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ijid.2023.11.021_bib0022","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/s12874-017-0338-0","article-title":"Double-adjustment in propensity score matching analysis: choosing a threshold for considering residual imbalance","volume":"17","author":"Nguyen","year":"2017","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0023","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1093\/oncolo\/oyab083","article-title":"Impact of immune checkpoint inhibitors on COVID-19 severity in patients with cancer","volume":"27","author":"Tan","year":"2022","journal-title":"Oncologist"},{"key":"10.1016\/j.ijid.2023.11.021_bib0024","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1001\/jamaoncol.2022.5357","article-title":"Interplay of immunosuppression and immunotherapy among patients with cancer and COVID-19","volume":"9","author":"Bakouny","year":"2023","journal-title":"JAMA Oncol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0025","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ijid.2022.08.007","article-title":"Pembrolizumab in combination with tocilizumab in high-risk hospitalized patients with COVID-19 (COPERNICO): a randomized proof-of-concept phase II study","volume":"123","author":"S\u00e1nchez-Conde","year":"2022","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.ijid.2023.11.021_bib0026","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1146\/annurev-pathol-042020-042741","article-title":"Immune checkpoint inhibitors for the treatment of cancer: clinical impact and mechanisms of response and resistance","volume":"16","author":"Bagchi","year":"2021","journal-title":"Annu Rev Pathol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0027","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/s41571-021-00552-7","article-title":"Enhancing immunotherapy in cancer by targeting emerging immunomodulatory pathways","volume":"19","author":"Kraehenbuehl","year":"2022","journal-title":"Nat Rev Clin Oncol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0028","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/S1470-2045(20)30314-4","article-title":"COVID-19 in patients with thoracic malignancies (TERAVOLT): first results of an international, registry-based, cohort study","volume":"21","author":"Garassino","year":"2020","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0029","series-title":"Treasure Island: StatPearls","article-title":"Emerging variants of SARS-CoV-2 and novel therapeutics against coronavirus (COVID-19)","author":"Aleem","year":"2022"},{"key":"10.1016\/j.ijid.2023.11.021_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2022.108565","article-title":"A review on evolution of emerging SARS-CoV-2 variants based on spike glycoprotein","volume":"105","author":"Ghosh","year":"2022","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.ijid.2023.11.021_bib0031","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2021-004157","article-title":"Impact of COVID-19 vaccination on the use of PD-1 inhibitor in treating patients with cancer: a real-world study","volume":"10","author":"Mei","year":"2022","journal-title":"J Immunother Cancer"},{"key":"10.1016\/j.ijid.2023.11.021_bib0032","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2020-004206","article-title":"Social media and vaccine hesitancy","volume":"5","author":"Wilson","year":"2020","journal-title":"BMJ Glob Health"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971223007828?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971223007828?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,2]],"date-time":"2024-06-02T08:01:26Z","timestamp":1717315286000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971223007828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":32,"alternative-id":["S1201971223007828"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2023.11.021","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Previous immune checkpoint inhibitor therapy is associated with decreased COVID-19-related hospitalizations and complications in patients with cancer: Results of a propensity-matched analysis of the OnCovid registry","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2023.11.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}]}}