{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T14:56:12Z","timestamp":1788533772078,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T00:00:00Z","timestamp":1715817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["TMA2015SF-998- MaReCa"],"award-info":[{"award-number":["TMA2015SF-998- MaReCa"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006338","name":"Vlaamse Interuniversitaire Raad","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022083","name":"VLIRUOS","doi-asserted-by":"publisher","award":["TZ2017TEA451A102"],"award-info":[{"award-number":["TZ2017TEA451A102"]}],"id":[{"id":"10.13039\/501100022083","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.ijid.2024.107102","type":"journal-article","created":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T13:51:49Z","timestamp":1718286709000},"page":"107102","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Lack of selection of antimalarial drug resistance markers after intermittent preventive treatment of schoolchildren (IPTsc) against malaria in northeastern Tanzania"],"prefix":"10.1016","volume":"146","author":[{"given":"Frederik","family":"Von Wowern","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geofrey","family":"Makenga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Wellmann Thomsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Wellmann Thomsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0040-7041","authenticated-orcid":false,"given":"Emma","family":"Filtenborg Hocke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vito","family":"Baraka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin H.","family":"Opot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel T.R.","family":"Minja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.A.","family":"Lusingu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5006-6364","authenticated-orcid":false,"given":"Jean-Pierre","family":"Van-geertruyden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6484-1165","authenticated-orcid":false,"given":"Helle","family":"Hansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3835-3333","authenticated-orcid":false,"given":"Michael","family":"Alifrangis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijid.2024.107102_bib0001","unstructured":"WHO World Malaria Report. 2022. https:\/\/www.who.int\/teams\/global-malaria-programme\/reports\/world-malaria-report-2022 [accessed 30 June 2024]."},{"issue":"11","key":"10.1016\/j.ijid.2024.107102_bib0002","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1111\/tmi.12374","article-title":"Malaria in school-age children in Africa: an increasingly important challenge","volume":"19","author":"Nankabirwa","year":"2014","journal-title":"Trop Med Int Health"},{"issue":"5","key":"10.1016\/j.ijid.2024.107102_bib0003","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0268654","article-title":"Attributable risk factors for asymptomatic malaria and anaemia and their association with cognitive and psychomotor functions in schoolchildren of north-eastern Tanzania","volume":"17","author":"Makenga","year":"2022","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.ijid.2024.107102_bib0004","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.4269\/ajtmh.12-0633","article-title":"Asymptomatic Plasmodium Infection and Cognition among Primary Schoolchildren in a High Malaria Transmission Setting in Uganda","volume":"88","author":"Nankabirwa","year":"2013","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.ijid.2024.107102_bib0005","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1186\/s12936-015-0988-5","article-title":"Efficacy and safety of intermittent preventive treatment for malaria in schoolchildren: a systematic review","volume":"14","author":"Matangila","year":"2015","journal-title":"Malar J"},{"issue":"10","key":"10.1016\/j.ijid.2024.107102_bib0006","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1093\/cid\/ciu150","article-title":"Impact of intermittent preventive treatment with dihydroartemisinin-piperaquine on malaria in Ugandan schoolchildren: a randomized, placebo-controlled trial","volume":"58","author":"Nankabirwa","year":"2014","journal-title":"Clin Infect Dis"},{"issue":"8","key":"10.1016\/j.ijid.2024.107102_bib0007","doi-asserted-by":"crossref","first-page":"e1277","DOI":"10.1016\/S2214-109X(23)00204-8","article-title":"Effectiveness and safety of intermittent preventive treatment with dihydroartemisinin-piperaquine or artesunate-amodiaquine for reducing malaria and related morbidities in schoolchildren in Tanzania: a randomised controlled trial","volume":"11","author":"Makenga","year":"2023","journal-title":"Lancet Glob Health"},{"issue":"5","key":"10.1016\/j.ijid.2024.107102_bib0008","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jiph.2022.03.015","article-title":"Molecular surveillance of chloroquine-resistant Plasmodium falciparum in sub-Saharan African countries after withdrawal of chloroquine for treatment of uncomplicated malaria: A systematic review","volume":"15","author":"Njiro","year":"2022","journal-title":"J Infect Public Health"},{"issue":"10","key":"10.1016\/j.ijid.2024.107102_bib0009","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1038\/s41591-020-1005-2","article-title":"Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda","volume":"26","author":"Uwimana","year":"2020","journal-title":"Nat Med"},{"issue":"13","key":"10.1016\/j.ijid.2024.107102_bib0010","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1056\/NEJMoa2101746","article-title":"Evidence of Artemisinin-Resistant Malaria in Africa","volume":"385","author":"Balikagala","year":"2021","journal-title":"N Engl J Med"},{"issue":"3","key":"10.1016\/j.ijid.2024.107102_bib0011","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S1473-3099(22)00593-X","article-title":"Prevalence of Plasmodium falciparum haplotypes associated with resistance to sulfadoxine-pyrimethamine and amodiaquine before and after upscaling of seasonal malaria chemoprevention in seven African countries: a genomic surveillance study","volume":"23","author":"Beshir","year":"2023","journal-title":"Lancet Infect Dis"},{"issue":"5","key":"10.1016\/j.ijid.2024.107102_bib0012","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1056\/NEJMoa1314981","article-title":"Spread of artemisinin resistance in Plasmodium falciparum malaria","volume":"371","author":"Ashley","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijid.2024.107102_bib0013","doi-asserted-by":"crossref","first-page":"11553","DOI":"10.1038\/ncomms11553","article-title":"Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies","volume":"7","author":"Veiga","year":"2016","journal-title":"Nat Commun"},{"issue":"5","key":"10.1016\/j.ijid.2024.107102_bib0014","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2018-000999","article-title":"Emerging implications of policies on malaria treatment: genetic changes in the Pfmdr-1 gene affecting susceptibility to artemether-lumefantrine and artesunate-amodiaquine in Africa","volume":"3","author":"Okell","year":"2018","journal-title":"BMJ Glob Health"},{"issue":"2","key":"10.1016\/j.ijid.2024.107102_bib0015","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/S1473-3099(16)30409-1","article-title":"Genetic markers associated with dihydroartemisinin-piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype-phenotype association study","volume":"17","author":"Amato","year":"2017","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"10.1016\/j.ijid.2024.107102_bib0016","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S1473-3099(15)00487-9","article-title":"Dihydroartemisinin-piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study","volume":"16","author":"Amaratunga","year":"2016","journal-title":"Lancet Infect Dis"},{"issue":"2","key":"10.1016\/j.ijid.2024.107102_bib0017","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S1473-3099(16)30415-7","article-title":"A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study","volume":"17","author":"Witkowski","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ijid.2024.107102_bib0018","doi-asserted-by":"crossref","DOI":"10.1016\/j.conctc.2020.100546","volume":"17","author":"Makenga","year":"2020","journal-title":"Contemp Clin Trials Commun"},{"issue":"3","key":"10.1016\/j.ijid.2024.107102_bib0019","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001788","article-title":"Ultra-sensitive detection of Plasmodium falciparum by amplification of multi-copy subtelomeric targets","volume":"12","author":"Hofmann","year":"2015","journal-title":"PLoS Med"},{"issue":"1","key":"10.1016\/j.ijid.2024.107102_bib0020","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1186\/s12936-019-2894-8","article-title":"Proof of concept: used malaria rapid diagnostic tests applied for parallel sequencing for surveillance of molecular markers of anti-malarial resistance in Bissau, Guinea-Bissau during 2014-2017","volume":"18","author":"Nag","year":"2019","journal-title":"Malar J"},{"key":"10.1016\/j.ijid.2024.107102_bib0021","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1038\/s41467-018-04104-z","article-title":"Plasmepsin II\u2013III copy number accounts for bimodal piperaquine resistance among Cambodian Plasmodium falciparum","volume":"9","author":"Bopp","year":"2018","journal-title":"Nat Commun"},{"issue":"8","key":"10.1016\/j.ijid.2024.107102_bib0022","doi-asserted-by":"crossref","first-page":"2946","DOI":"10.1128\/JCM.00276-11","article-title":"Development of a highly sensitive genus-specific quantitative reverse transcriptase real-time PCR assay for detection and quantitation of plasmodium by amplifying RNA and DNA of the 18S rRNA genes","volume":"49","author":"Kamau","year":"2011","journal-title":"J Clin Microbiol"},{"issue":"3","key":"10.1016\/j.ijid.2024.107102_bib0023","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1128\/AAC.00875-06","article-title":"Amodiaquine and artemether-lumefantrine select distinct alleles of the Plasmodium falciparum mdr1 gene in Tanzanian children treated for uncomplicated malaria","volume":"51","author":"Humphreys","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"10.1016\/j.ijid.2024.107102_bib0024","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/s12936-019-2730-1","article-title":"Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria and prevalence of Pfk13 and Pfmdr1 polymorphisms after a decade of using artemisinin-based combination therapy in mainland Tanzania","volume":"18","author":"Ishengoma","year":"2019","journal-title":"Malar J"},{"issue":"10","key":"10.1016\/j.ijid.2024.107102_bib0025","doi-asserted-by":"crossref","first-page":"5649","DOI":"10.1128\/AAC.00920-16","article-title":"Intermittent Preventive Treatment with Dihydroartemisinin-Piperaquine in Ugandan Schoolchildren Selects for Plasmodium falciparum Transporter Polymorphisms That Modify Drug Sensitivity","volume":"60","author":"Nankabirwa","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"issue":"1","key":"10.1016\/j.ijid.2024.107102_bib0026","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/s12936-022-04115-8","article-title":"Malaria chemoprevention and drug resistance: a review of the literature and policy implications","volume":"21","author":"Plowe","year":"2022","journal-title":"Malar J"},{"key":"10.1016\/j.ijid.2024.107102_bib0027","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ijid.2023.11.026","article-title":"Identification of the PfK13 mutations R561H and P441L in Democratic Republic of Congo (DRC)","volume":"139","author":"Mesia Kahunu","year":"2024","journal-title":"Int J Infect Dis"},{"issue":"1","key":"10.1016\/j.ijid.2024.107102_bib0028","doi-asserted-by":"crossref","first-page":"3500","DOI":"10.1038\/s41598-020-60549-7","article-title":"Detection of mutations associated with artemisinin resistance at k13-propeller gene and a near complete return of chloroquine susceptible falciparum malaria in Southeast of Tanzania","volume":"10","author":"Bwire","year":"2020","journal-title":"Sci Rep"},{"issue":"7","key":"10.1016\/j.ijid.2024.107102_bib0029","doi-asserted-by":"crossref","first-page":"3615","DOI":"10.1128\/AAC.06350-11","article-title":"Pfmdr1 Amplification Is Related to Increased Plasmodium falciparum In Vitro Sensitivity to the Bisquinoline Piperaquine","volume":"56","author":"Veiga","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijid.2024.107102_bib0030","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1186\/s12936-020-03249-x","article-title":"Development of copy number assays for detection and surveillance of piperaquine resistance associated plasmepsin 2\/3 copy number variation in Plasmodium falciparum","volume":"19","author":"Ansbro","year":"2020","journal-title":"Malar J"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971224001735?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971224001735?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T15:44:48Z","timestamp":1728315888000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971224001735"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":30,"alternative-id":["S1201971224001735"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2024.107102","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lack of selection of antimalarial drug resistance markers after intermittent preventive treatment of schoolchildren (IPTsc) against malaria in northeastern Tanzania","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2024.107102","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}],"article-number":"107102"}}