{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T07:05:18Z","timestamp":1782457518357,"version":"3.54.5"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T00:00:00Z","timestamp":1729036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004844","name":"National Cheng Kung University Hospital","doi-asserted-by":"publisher","award":["NCKUH-11306002"],"award-info":[{"award-number":["NCKUH-11306002"]}],"id":[{"id":"10.13039\/501100004844","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004844","name":"National Cheng Kung University Hospital","doi-asserted-by":"publisher","award":["NCKUH-11308001"],"award-info":[{"award-number":["NCKUH-11308001"]}],"id":[{"id":"10.13039\/501100004844","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC111-2629-B-006-003-MY2"],"award-info":[{"award-number":["NSTC111-2629-B-006-003-MY2"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC112-2314-B-006-022-MY3"],"award-info":[{"award-number":["NSTC112-2314-B-006-022-MY3"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.ijid.2024.107273","type":"journal-article","created":{"date-parts":[[2024,10,22]],"date-time":"2024-10-22T07:28:09Z","timestamp":1729582089000},"page":"107273","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Asymptomatic enteric pathogen carriage and its association with proton pump inhibitors use in men who have sex with men in Taiwan, 2019-2022"],"prefix":"10.1016","volume":"149","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9391-1561","authenticated-orcid":false,"given":"Chin-Shiang","family":"Tsai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan-Yao","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Lin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szu-Ying","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-Jun","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Fang","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huey-Pin","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiun-Ling","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7497-149X","authenticated-orcid":false,"given":"Wen-Chien","family":"Ko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijid.2024.107273_bib0001","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1056\/NEJMra022710","article-title":"Amebiasis","volume":"348","author":"Haque","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijid.2024.107273_bib0002","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.actatropica.2013.12.025","article-title":"Sexual transmission of giardiasis: a neglected route of spread?","volume":"132","author":"Escobedo","year":"2014","journal-title":"Acta Trop"},{"key":"10.1016\/j.ijid.2024.107273_bib0003","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1086\/510591","article-title":"Another perfect storm: Shigella, men who have sex with men, and HIV","volume":"44","author":"Daskalakis","year":"2007","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijid.2024.107273_bib0004","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1136\/sextrans-2021-055274","article-title":"Shigella is common in symptomatic and asymptomatic men who have sex with men visiting a sexual health clinic in Amsterdam","volume":"98","author":"Braam","year":"2022","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ijid.2024.107273_bib0005","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1093\/cid\/ciz1060","article-title":"International spread of multidrug-resistant Campylobacter coli in men who have sex with men in Washington State and Qu\u00e9bec, 2015\u20132018","volume":"71","author":"Greninger","year":"2019","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijid.2024.107273_bib0006","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0008400","article-title":"Ongoing transmission of Entamoeba histolytica among newly diagnosed people living with HIV in Taiwan, 2009-2018","volume":"14","author":"Huang","year":"2020","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.ijid.2024.107273_bib0007","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1136\/sextrans-2016-053057","article-title":"Prevalence and characteristics of gastrointestinal infections in men who have sex with men diagnosed with rectal chlamydia infection in the UK: an \u2018unlinked anonymous\u2019 cross-sectional study","volume":"94","author":"Hughes","year":"2018","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ijid.2024.107273_bib0008","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1177\/09564624231168217","article-title":"British Association of Sexual Health and HIV (BASHH) United Kingdom national guideline for the management of sexually transmitted enteric infections 2023","volume":"34","author":"Richardson","year":"2023","journal-title":"Int J STD AIDS"},{"key":"10.1016\/j.ijid.2024.107273_bib0009","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.jinf.2022.10.033","article-title":"Prevalence and risk factors of bacterial enteric pathogens in men who have sex with men: a cross-sectional study at the UK's largest sexual health service","volume":"86","author":"Mitchell","year":"2023","journal-title":"J Infect"},{"key":"10.1016\/j.ijid.2024.107273_bib0010","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1136\/sextrans-2022-055583","article-title":"Factors associated with sexually transmitted Shigella in men who have sex with men: a systematic review","volume":"99","author":"Siddiq","year":"2023","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ijid.2024.107273_bib0011","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/S1473-3099(22)00813-1","article-title":"Sexually acquired enteric infections among men who have sex with men","volume":"23","author":"Chen","year":"2023","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ijid.2024.107273_bib0012","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/cid\/ciz783","article-title":"Gastroenteritis in men who have sex with men in Seattle, Washington, 2017\u20132018","volume":"71","author":"Newman","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijid.2024.107273_bib0013","doi-asserted-by":"crossref","first-page":"ofz326","DOI":"10.1093\/ofid\/ofz326","article-title":"Risk factors for asymptomatic enteric pathogen detection among men who have sex with men","volume":"6","author":"Williamson","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.ijid.2024.107273_bib0014","doi-asserted-by":"crossref","first-page":"ofab411","DOI":"10.1093\/ofid\/ofab411","article-title":"Prevalence of gastrointestinal pathogens detected by multiplex polymerase chain reaction in a prospective cohort of men who have sex with men taking human immunodeficiency virus preexposure prophylaxis\u2014New York City, 2019-2020","volume":"8","author":"Purpura","year":"2021","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.ijid.2024.107273_bib0015","doi-asserted-by":"crossref","DOI":"10.1136\/sextrans-2024-056183","article-title":"Estimated prevalence and associations of sexually transmissible bacterial enteric pathogens in asymptomatic men who have sex with men: a systematic review and meta-analysis","author":"Richardson","year":"2024","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ijid.2024.107273_bib0016","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1111\/j.1365-2036.2011.04874.x","article-title":"Systematic review: the use of proton pump inhibitors and increased susceptibility to enteric infection","volume":"34","author":"Bavishi","year":"2011","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.ijid.2024.107273_bib0017","doi-asserted-by":"crossref","first-page":"271","DOI":"10.7326\/0003-4819-78-2-271","article-title":"Influence of gastric acidity on bacterial and parasitic enteric infections: a perspective","volume":"78","author":"Giannella","year":"1973","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.ijid.2024.107273_bib0018","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1080\/22221751.2022.2031309","article-title":"Changing epidemiology of shigellosis in Taiwan, 2010-2019: an emerging threat to HIV-infected patients and men who have sex with men","volume":"11","author":"Tsai","year":"2022","journal-title":"Emerg Microbes Infect"},{"key":"10.1016\/j.ijid.2024.107273_bib0019","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.jmii.2023.01.007","article-title":"Characteristics of rectal chlamydia among men who have sex with men in southern Taiwan, 2020\u20132022: an emerging threat of rectal lymphogranuloma venereum L2b","volume":"56","author":"Tsai","year":"2023","journal-title":"J Microbiol Immunol Infect"},{"key":"10.1016\/j.ijid.2024.107273_bib0020","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1093\/infdis\/jix419","article-title":"Does active oral sex contribute to female infertility?","volume":"216","author":"Bavoil","year":"2017","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ijid.2024.107273_bib0021","doi-asserted-by":"crossref","first-page":"207","DOI":"10.5414\/CPP41207","article-title":"Trends in prescribing proton pump inhibitors in Taiwan: 1997-2000","volume":"41","author":"Chen","year":"2003","journal-title":"Int J Clin Pharmacol Ther"},{"key":"10.1016\/j.ijid.2024.107273_bib0022","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1007\/s00228-023-03534-z","article-title":"Proton pump inhibitor use: systematic review of global trends and practices","volume":"79","author":"Shanika","year":"2023","journal-title":"Eur J Clin Pharmacol"},{"key":"10.1016\/j.ijid.2024.107273_bib0023","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1017\/S0950268815002332","article-title":"Association between use of proton pump inhibitors and non-typhoidal salmonellosis identified following investigation into an outbreak of Salmonella mikawasima in the UK, 2013","volume":"144","author":"Freeman","year":"2016","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.ijid.2024.107273_bib0024","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1093\/cid\/ciu628","article-title":"Association between recent use of proton pump inhibitors and nontyphoid salmonellosis: a nested case-control study","volume":"59","author":"Wu","year":"2014","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijid.2024.107273_bib0025","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1136\/bmj.312.7028.414","article-title":"Omeprazole as a risk factor for Campylobacter gastroenteritis: case-control study","volume":"312","author":"Neal","year":"1996","journal-title":"BMJ"},{"key":"10.1016\/j.ijid.2024.107273_bib0026","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.4315\/0362-028X-64.8.1162","article-title":"The effect of temperature and low pH on survival of Shigella flexneri in broth","volume":"64","author":"Zaika","year":"2001","journal-title":"J Food Prot"},{"key":"10.1016\/j.ijid.2024.107273_bib0027","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/s40261-017-0519-y","article-title":"Acid-suppressive therapy and risk of infections: pros and cons","volume":"37","author":"Fisher","year":"2017","journal-title":"Clin Drug Investig"},{"key":"10.1016\/j.ijid.2024.107273_bib0028","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1007\/BF02349646","article-title":"Proton-pump inhibition and gastric giardiasis: a causal or casual association?","volume":"30","author":"Reynaert","year":"1995","journal-title":"J Gastroenterol"},{"key":"10.1016\/j.ijid.2024.107273_bib0029","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003489","article-title":"Host immune response to intestinal amebiasis","volume":"9","author":"Moonah","year":"2013","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.ijid.2024.107273_bib0030","doi-asserted-by":"crossref","first-page":"e102","DOI":"10.1002\/cpmc.102","article-title":"Giardia lamblia: laboratory maintenance, lifecycle induction, and infection of murine models","volume":"57","author":"Fink","year":"2020","journal-title":"Curr Protoc Microbiol"},{"key":"10.1016\/j.ijid.2024.107273_bib0031","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1038\/s41598-020-57612-8","article-title":"Long-term proton pump inhibitor administration caused physiological and microbiota changes in rats","volume":"10","author":"Yang","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijid.2024.107273_bib0032","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1136\/gut.33.5.617","article-title":"Effects of omeprazole on neutrophil chemotaxis, super oxide production, degranulation, and translocation of cytochrome b-245","volume":"33","author":"Wandall","year":"1992","journal-title":"Gut"},{"key":"10.1016\/j.ijid.2024.107273_bib0033","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0009849","article-title":"High prevalence of small intestine bacteria overgrowth and asymptomatic carriage of enteric pathogens in stunted children in Antananarivo, Madagascar","volume":"16","author":"Collard","year":"2022","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.ijid.2024.107273_bib0034","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s10508-011-9770-0","article-title":"Felching among men who engage in barebacking (unprotected anal sex)","volume":"41","author":"Klein","year":"2012","journal-title":"Arch Sex Behav"},{"key":"10.1016\/j.ijid.2024.107273_bib0035","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/QCO.0000000000000423","article-title":"Recent epidemiology of sexually transmissible enteric infections in men who have sex with men","volume":"31","author":"Mitchell","year":"2018","journal-title":"Curr Opin Infect Dis"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971224003448?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971224003448?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,9]],"date-time":"2025-01-09T11:35:17Z","timestamp":1736422517000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971224003448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":35,"alternative-id":["S1201971224003448"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2024.107273","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Asymptomatic enteric pathogen carriage and its association with proton pump inhibitors use in men who have sex with men in Taiwan, 2019-2022","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2024.107273","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}],"article-number":"107273"}}