{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T02:03:27Z","timestamp":1774317807035,"version":"3.50.1"},"reference-count":11,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:00:00Z","timestamp":1740096000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.ijid.2025.107861","type":"journal-article","created":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T23:25:01Z","timestamp":1740871501000},"page":"107861","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Innovative approach for the clinical development of a Chlamydia trachomatis vaccine through a human challenge model in women"],"prefix":"10.1016","volume":"154","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8654-6634","authenticated-orcid":false,"given":"Craig R.","family":"Cohen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijid.2025.107861_bib0001","doi-asserted-by":"crossref","DOI":"10.1093\/femspd\/ftae017","article-title":"Advances in vaccine development for Chlamydia trachomatis","volume":"82","author":"Poston","year":"2024","journal-title":"Pathog Dis"},{"key":"10.1016\/j.ijid.2025.107861_bib0002","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1136\/sti.75.1.21","article-title":"Pathogenesis of Chlamydia induced pelvic inflammatory disease","volume":"75","author":"Cohen","year":"1999","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ijid.2025.107861_bib0003","doi-asserted-by":"crossref","unstructured":"den Heijer CDJ, Hoebe CJPA, Driessen JHM, Wolffs P, van den Broek IVF, Hoenderboom BM, et al. Chlamydia trachomatis and the risk of pelvic inflammatory disease, ectopic pregnancy, and female infertility: a retrospective cohort study among primary care patients. Clin Infect Dis 2019;69:1517\u201325. https:\/\/doi.org\/10.1093\/cid\/ciz429. Erratum in: Clin Infect Dis 2020;70:2459. https:\/\/doi.org\/10.1093\/cid\/ciz897.","DOI":"10.1093\/cid\/ciz897"},{"key":"10.1016\/j.ijid.2025.107861_bib0004","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1086\/599095","article-title":"Frequency and magnitude of Chlamydia trachomatis elementary body- and heat shock protein 60-stimulated interferon gamma responses in peripheral blood mononuclear cells and endometrial biopsy samples from women with high exposure to infection","volume":"199","author":"Ondondo","year":"2009","journal-title":"J Infect Dis"},{"key":"10.1016\/j.ijid.2025.107861_bib0005","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/S1473-3099(19)30279-8","article-title":"Safety and immunogenicity of the chlamydia vaccine candidate CTH522 adjuvanted with CAF01 liposomes or aluminium hydroxide: a first-in-human, randomised, double-blind, placebo-controlled, phase 1 trial","volume":"19","author":"Abraham","year":"2019","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ijid.2025.107861_bib0006","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/S1473-3099(24)00147-6","article-title":"An investigation of trachoma vaccine regimens by the chlamydia vaccine CTH522 administered with cationic liposomes in healthy adults (CHLM-02): a phase 1, double-blind trial","volume":"24","author":"Pollock","year":"2024","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ijid.2025.107861_bib0007","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/S1473-3099(19)30290-7","article-title":"First genital chlamydia vaccine enters in-human clinical trial","volume":"19","author":"Poston","year":"2019","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ijid.2025.107861_bib0008","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.contraception.2015.01.004","article-title":"Pathogenesis of fallopian tube damage caused by Chlamydia trachomatis infections","volume":"92","author":"Hafner","year":"2015","journal-title":"Contraception"},{"key":"10.1016\/j.ijid.2025.107861_bib0009","first-page":"438","article-title":"Immunogenetic correlates for Chlamydia trachomatis-associated tubal infertility","volume":"101","author":"Cohen","year":"2003","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ijid.2025.107861_bib0010","doi-asserted-by":"crossref","first-page":"123","DOI":"10.3389\/fmicb.2011.00123","article-title":"Experimental gonococcal infection in male volunteers: cumulative experience with Neisseria gonorrhoeae Strains FA1090 and MS11mkC","volume":"2","author":"Hobbs","year":"2011","journal-title":"Front Microbiol"},{"key":"10.1016\/j.ijid.2025.107861_bib0011","doi-asserted-by":"crossref","DOI":"10.1128\/cmr.00008-21","article-title":"Controlled human infection models to accelerate vaccine development","volume":"35","author":"Choy","year":"2022","journal-title":"Clin Microbiol Rev"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971225000840?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971225000840?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T10:24:55Z","timestamp":1746786295000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971225000840"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":11,"alternative-id":["S1201971225000840"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2025.107861","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Innovative approach for the clinical development of a Chlamydia trachomatis vaccine through a human challenge model in women","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2025.107861","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}],"article-number":"107861"}}