{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T09:57:09Z","timestamp":1786615029186,"version":"build-2736575974"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T00:00:00Z","timestamp":1752537600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005366","name":"University of Oslo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005366","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.ijid.2025.107989","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:38:54Z","timestamp":1752712734000},"page":"107989","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["A case of fatal hemorrhagic fever associated with tick-borne encephalitis virus infection"],"prefix":"10.1016","volume":"159","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7916-0717","authenticated-orcid":false,"given":"Aleksander Rygh","family":"Holten","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas Wigmostad","family":"Bjerkhaug","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urusha","family":"Maharjan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rikard","family":"Rykkvin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thijs","family":"Hagen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00f8rre","family":"Fevang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Else","family":"Quist-Paulsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liv","family":"Hesstvedt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanne Regine","family":"Hognestad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian","family":"Alfsnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c5shild Kristine","family":"Andreassen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oona","family":"Dunlop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijid.2025.107989_bib0001","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.virol.2006.09.015","article-title":"Genetic characterization of tick-borne flaviviruses: new insights into evolution, pathogenetic determinants and taxonomy","volume":"361","author":"Grard","year":"2007","journal-title":"Virology"},{"key":"10.1016\/j.ijid.2025.107989_bib0002","unstructured":"European Centre for Disease Prevention and Control. Tick-borne encephalitis - Annual Epidemiological Report for 2022. Stokholm: European Centre for Disease Prevention and Control, 2024."},{"key":"10.1016\/j.ijid.2025.107989_bib0003","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.3201\/eid1012.040598","article-title":"First human cases of tickborne encephalitis","volume":"10","author":"Skarpaas","year":"2004","journal-title":"Norway. Emerg Infect Dis"},{"key":"10.1016\/j.ijid.2025.107989_bib0004","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ejim.2019.01.004","article-title":"Tick-borne encephalitis in Europe: a brief update on epidemiology, diagnosis, prevention, and treatment","volume":"62","author":"Riccardi","year":"2019","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.ijid.2025.107989_bib0005","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1007\/s10096-024-04855-2","article-title":"Clinical characteristics and factors affecting disease severity in hospitalized tick-borne encephalitis patients in Norway from 2018 to 2022","volume":"43","author":"Skudal","year":"2024","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.ijid.2025.107989_bib0006","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1093\/molbev\/msu300","article-title":"IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies","volume":"32","author":"Nguyen","year":"2015","journal-title":"Mol Biol Evol"},{"key":"10.1016\/j.ijid.2025.107989_bib0007","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1099\/vir.0.035766-0","article-title":"Rate of evolution and molecular epidemiology of tick-borne encephalitis virus in Europe, including two isolations from the same focus 44 years apart","volume":"93","author":"Uzc\u00e1tegui","year":"2012","journal-title":"J Gen Virol"},{"key":"10.1016\/j.ijid.2025.107989_bib0008","doi-asserted-by":"crossref","DOI":"10.1038\/srep39265","article-title":"The role of the poly(A) tract in the replication and virulence of tick-borne encephalitis virus","volume":"6","author":"Asghar","year":"2016","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijid.2025.107989_bib0009","first-page":"743","article-title":"Tick-borne encephalitis with hemorrhagic syndrome, Novosibirsk region","volume":"9","author":"Ternovoi","year":"2003","journal-title":"Russia, 1999. Emerg Infect Dis"},{"key":"10.1016\/j.ijid.2025.107989_bib0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.ttbdis.2023.102273","article-title":"A fatal case of tick-borne encephalitis in an immunocompromised patient: case report from Northeastern Poland and review of literature","volume":"15","author":"Czarnowska","year":"2024","journal-title":"Ticks Tick Borne Dis"},{"key":"10.1016\/j.ijid.2025.107989_bib0011","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s10875-024-01718-5","article-title":"Severe tick-borne encephalitis (TBE) in a patient with X-linked agammaglobulinemia; treatment with TBE virus IgG positive plasma, clinical outcome and T cell responses","volume":"44","author":"Hedin","year":"2024","journal-title":"J Clin Immunol"},{"key":"10.1016\/j.ijid.2025.107989_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.jinf.2025.106481","article-title":"Detection of tick-borne encephalitis virus RNA in patient samples at different stages of infection","volume":"90","author":"Kriha","year":"2025","journal-title":"J Infect"},{"key":"10.1016\/j.ijid.2025.107989_bib0013","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1016\/j.ttbdis.2016.07.002","article-title":"Detection of Rickettsia helvetica in Ixodes ricinus infesting wild and domestic animals and in a botfly larva (Cephenemyia stimulator) infesting roe deer in Germany","volume":"7","author":"Scheid","year":"2016","journal-title":"Ticks Tick Borne Dis"},{"key":"10.1016\/j.ijid.2025.107989_bib0014","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/jvec.12225","article-title":"Detection of Lyme disease and anaplasmosis pathogens via PCR in Pennsylvania deer ked","volume":"41","author":"Buss","year":"2016","journal-title":"J Vector Ecol"},{"issue":"4","key":"10.1016\/j.ijid.2025.107989_bib16","doi-asserted-by":"crossref","first-page":"102501","DOI":"10.1016\/j.ttbdis.2025.102501","article-title":"Novel variants of tick-borne encephalitis virus from patient and tick samples in Norway","volume":"16","author":"Maharjan","year":"2025","journal-title":"Ticks Tick Borne Dis"},{"key":"10.1016\/j.ijid.2025.107989_bib0015","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1080\/00365540600868297","article-title":"TBE in Aland Islands 1959\u20132005: Kumlinge disease","volume":"38","author":"Wahlberg","year":"2006","journal-title":"Scand J Infect Dis"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971225002139?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971225002139?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T21:31:37Z","timestamp":1761427897000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971225002139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":16,"alternative-id":["S1201971225002139"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2025.107989","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A case of fatal hemorrhagic fever associated with tick-borne encephalitis virus infection","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2025.107989","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}],"article-number":"107989"}}