{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T14:44:04Z","timestamp":1791125044827,"version":"4.1.0"},"reference-count":13,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T00:00:00Z","timestamp":1757980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82372168"],"award-info":[{"award-number":["82372168"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32470145"],"award-info":[{"award-number":["32470145"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFC2701800"],"award-info":[{"award-number":["2021YFC2701800"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["23ZR1461600"],"award-info":[{"award-number":["23ZR1461600"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["ZD2021CY001"],"award-info":[{"award-number":["ZD2021CY001"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.ijid.2025.108075","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T01:37:11Z","timestamp":1758591431000},"page":"108075","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Personalized aerosolized bacteriophage treatment of a pulmonary infection due to carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae in an infant"],"prefix":"10.1016","volume":"160","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1431-9787","authenticated-orcid":false,"given":"Huiyuan","family":"Yan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nannan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlan","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjie","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengjun","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianfang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanqing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leiyan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiming","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yixue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caiyan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weili","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoping","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gangfeng","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.ijid.2025.108075_bib0001","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/S1473-3099(25)00118-5","article-title":"The WHO Bacterial Priority Pathogens List 2024: a prioritisation study to guide research, development, and public health strategies against antimicrobial resistance","volume":"25","author":"Sati","year":"2025","journal-title":"Lancet Infect Dis"},{"issue":"12","key":"10.1016\/j.ijid.2025.108075_bib0002","doi-asserted-by":"crossref","first-page":"5255","DOI":"10.1007\/s00431-024-05752-8","article-title":"Risk factors for multidrug-resistant bacteria in critically ill children and MDR score development","volume":"183","author":"Gonz\u00e1lez-Anleo","year":"2024","journal-title":"Eur J Pediatr"},{"issue":"4","key":"10.1016\/j.ijid.2025.108075_bib0003","doi-asserted-by":"crossref","first-page":"349","DOI":"10.23736\/S0026-4946.17.04284-0","article-title":"Ventilator associated pneumonia due to carbapenem resistant microorganisms in children","volume":"71","author":"Kara","year":"2019","journal-title":"Minerva Pediatr"},{"issue":"6","key":"10.1016\/j.ijid.2025.108075_bib0004","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1038\/s41564-024-01705-x","article-title":"Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multicentre, multinational, retrospective observational study","volume":"9","author":"Pirnay","year":"2024","journal-title":"Nat Microbiol"},{"issue":"1","key":"10.1016\/j.ijid.2025.108075_bib0005","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1080\/22221751.2021.1902754","article-title":"Pre-optimized phage therapy on secondary Acinetobacter baumannii infection in four critical COVID-19 patients","volume":"10","author":"Wu","year":"2021","journal-title":"Emerg Microbes Infect"},{"issue":"9","key":"10.1016\/j.ijid.2025.108075_bib0006","doi-asserted-by":"crossref","DOI":"10.15252\/emmm.202113936","article-title":"Bacterial lysis, autophagy and innate immune responses during adjunctive phage therapy in a child","volume":"13","author":"Khatami","year":"2021","journal-title":"EMBO Mol Med"},{"issue":"1","key":"10.1016\/j.ijid.2025.108075_bib0007","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/s44259-024-00045-4","article-title":"Phage therapy could be key to conquering persistent bacterial lung infections in children","volume":"2","author":"Sithu Shein","year":"2024","journal-title":"NPJ Antimicrob Resist"},{"key":"10.1016\/j.ijid.2025.108075_bib0008","first-page":"70","article-title":"The potential of bacteriophage therapy in the treatment of paediatric respiratory infections","volume":"44","author":"Jones","year":"2022","journal-title":"Paediatr Respir Rev"},{"key":"10.1016\/j.ijid.2025.108075_bib0009","article-title":"Phage therapy for extensively drug resistant Acinetobacter baumannii infection: case report and in vivo evaluation of the distribution of phage and the impact on gut microbiome","volume":"11","author":"Qu","year":"2024","journal-title":"Front Med (Lausanne)"},{"issue":"166","key":"10.1016\/j.ijid.2025.108075_bib0010","doi-asserted-by":"crossref","DOI":"10.1183\/16000617.0121-2022","article-title":"Phage therapy for pulmonary infections: lessons from clinical experiences and key considerations","volume":"31","author":"Mitropoulou","year":"2022","journal-title":"Eur Respir Rev"},{"issue":"2","key":"10.1016\/j.ijid.2025.108075_bib0011","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/s41575-021-00536-z","article-title":"Bacteriophages and their potential for treatment of gastrointestinal diseases","volume":"19","author":"Duan","year":"2022","journal-title":"Nat Rev Gastroenterol Hepatol"},{"issue":"12","key":"10.1016\/j.ijid.2025.108075_bib0012","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2022-065401","article-title":"Standardised treatment and monitoring protocol to assess safety and tolerability of bacteriophage therapy for adult and paediatric patients (STAMP study): protocol for an open-label, single-arm trial","volume":"12","author":"Khatami","year":"2022","journal-title":"BMJ Open"},{"issue":"9","key":"10.1016\/j.ijid.2025.108075_bib0013","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1164\/rccm.201904-0839LE","article-title":"Bacteriophage therapy of ventilator-associated pneumonia and empyema caused by Pseudomonas aeruginosa","volume":"200","author":"Maddocks","year":"2019","journal-title":"Am J Respir Crit Care Med"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971225002978?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971225002978?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T14:52:42Z","timestamp":1773154362000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971225002978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":13,"alternative-id":["S1201971225002978"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2025.108075","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Personalized aerosolized bacteriophage treatment of a pulmonary infection due to carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae in an infant","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2025.108075","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}],"article-number":"108075"}}