{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T14:01:12Z","timestamp":1778162472954,"version":"3.51.4"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T00:00:00Z","timestamp":1762992000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004337","name":"Roche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004337","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.ijid.2025.108228","type":"journal-article","created":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T08:45:58Z","timestamp":1763628358000},"page":"108228","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Evaluation of Mycoplasma genitalium positivity and co-infection with Chlamydia trachomatis and\/or Neisseria gonorrhoeae at various care sites across the United States"],"prefix":"10.1016","volume":"162","author":[{"given":"Rebecca","family":"Lillis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodney","family":"Arcenas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christy M.","family":"Boraas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven E.","family":"Chavoustie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"LaShonda","family":"Crane","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"d\u2019Empaire","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron C.","family":"Ermel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenn","family":"Harnett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Hinestrosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stacey","family":"House","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony","family":"Mills","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"Poblete","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Van Der Pol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijid.2025.108228_bib0001","doi-asserted-by":"crossref","first-page":"e02124","DOI":"10.1128\/JCM.02124-19","article-title":"Mycoplasma genitalium detection in urogenital specimens from symptomatic and asymptomatic men and women by use of the Cobas TV\/MG test","volume":"58","author":"Van Der Pol","year":"2020","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijid.2025.108228_bib0002","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/S1473-3099(18)30506-1","article-title":"Mycoplasma genitalium: a potential new superbug","volume":"18","author":"Kirby","year":"2018","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ijid.2025.108228_bib0003","doi-asserted-by":"crossref","first-page":"2901","DOI":"10.1093\/jac\/dkac281","article-title":"Challenges of in vitro propagation and antimicrobial susceptibility testing of Mycoplasma genitalium","volume":"77","author":"Pitt","year":"2022","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijid.2025.108228_bib0004","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1136\/sextrans-2013-051467","article-title":"Association between Mycoplasma genitalium infection and HIV acquisition among female sex workers in Uganda: evidence from a nested case-control study","volume":"90","author":"Vandepitte","year":"2014","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ijid.2025.108228_bib0005","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1097\/QAD.0b013e328323da3e","article-title":"Association of Mycoplasma genitalium and HIV infection: a systematic review and meta-analysis","volume":"23","author":"Napierala Mavedzenge","year":"2009","journal-title":"AIDS"},{"key":"10.1016\/j.ijid.2025.108228_bib0006","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1093\/cid\/ciad405","article-title":"Mycoplasma genitalium in the US (MyGeniUS): surveillance data from sexual health clinics in 4 US regions","volume":"77","author":"Manhart","year":"2023","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijid.2025.108228_bib0007","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr7004a1","article-title":"Sexually transmitted infections treatment guidelines, 2021","volume":"70","author":"Workowski","year":"2021","journal-title":"MMWR Recomm Rep"},{"key":"10.1016\/j.ijid.2025.108228_bib0008","doi-asserted-by":"crossref","first-page":"548","DOI":"10.2471\/BLT.18.228486","article-title":"Chlamydia, gonorrhoea, trichomoniasis and syphilis: global prevalence and incidence estimates, 2016","volume":"97","author":"Rowley","year":"2019","journal-title":"Bull World Health Organ"},{"key":"10.1016\/j.ijid.2025.108228_bib0009","doi-asserted-by":"crossref","first-page":"e235","DOI":"10.1016\/S1473-3099(17)30310-9","article-title":"Sexually transmitted infections: challenges ahead","volume":"17","author":"Unemo","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.ijid.2025.108228_bib0010","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/jdv.16913","article-title":"Sexual behaviour, STI knowledge and Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) prevalence in an asymptomatic cohort in Ruhr-area, Germany: PreYoungGo study","volume":"35","author":"Skaletz-Rorowski","year":"2021","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.ijid.2025.108228_bib0011","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1097\/OLQ.0000000000001493","article-title":"Frequency and correlates of Mycoplasma genitalium antimicrobial resistance mutations and their association with treatment outcomes: findings from a national sentinel surveillance pilot in England","volume":"48","author":"Fifer","year":"2021","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ijid.2025.108228_bib0012","doi-asserted-by":"crossref","DOI":"10.3201\/eid2808.220094","article-title":"Weighing potential benefits and harms of Mycoplasma genitalium testing and treatment approaches","volume":"28","author":"Manhart","year":"2022","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.ijid.2025.108228_bib0013","series-title":"Antibiotic threats in the United States","year":"2019"},{"key":"10.1016\/j.ijid.2025.108228_bib0014","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1136\/sextrans-2017-053384","article-title":"Prevalence of Mycoplasma genitalium in different population groups: systematic review and meta-analysis","volume":"94","author":"Baumann","year":"2018","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.ijid.2025.108228_bib0015","doi-asserted-by":"crossref","first-page":"477","DOI":"10.14745\/ccdr.v49i1112a03","article-title":"Mycoplasma genitalium infection among gay, bisexual and other men who have sex with men in Montr\u00e9al, Canada","volume":"49","author":"L\u00ea","year":"2023","journal-title":"Can Commun Dis Rep"},{"key":"10.1016\/j.ijid.2025.108228_bib0016","doi-asserted-by":"crossref","first-page":"e160","DOI":"10.1097\/OLQ.0000000000001394","article-title":"Prevalence of urogenital Mycoplasma genitalium infection, United States, 2017 to 2018","volume":"48","author":"Torrone","year":"2021","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ijid.2025.108228_bib0017","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1177\/0956462416630675","article-title":"Prevalence of Mycoplasma genitalium in men with urethritis and in high risk asymptomatic males in Tel Aviv: a prospective study","volume":"28","author":"Gottesman","year":"2017","journal-title":"Int J STD AIDS"},{"key":"10.1016\/j.ijid.2025.108228_bib0018","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.eimc.2017.01.006","article-title":"Mycoplasma genitalium in Spain: prevalence of genital infection and frequency of resistance to macrolides","volume":"36","author":"Asenjo","year":"2018","journal-title":"Enferm Infecc Microbiol Clin (Engl Ed)"},{"key":"10.1016\/j.ijid.2025.108228_bib0019","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/OLQ.0000000000000540","article-title":"Quantitative real-time polymerase chain reaction for the diagnosis of Mycoplasma genitalium infection in South African men with and without symptoms of urethritis","volume":"44","author":"le Roux","year":"2017","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ijid.2025.108228_bib0020","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.diagmicrobio.2015.03.016","article-title":"Detection of Mycoplasma genitalium from male primary urine specimens: an epidemiologic dichotomy with Trichomonas vaginalis","volume":"82","author":"Napierala","year":"2015","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.ijid.2025.108228_bib0021","doi-asserted-by":"crossref","first-page":"122.e1","DOI":"10.1016\/j.cmi.2016.10.028","article-title":"Mycoplasma genitalium and Trichomonas vaginalis in France: a point prevalence study in people screened for sexually transmitted diseases","volume":"23","author":"Pereyre","year":"2017","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.ijid.2025.108228_bib0022","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1080\/23744235.2017.1366044","article-title":"Prevalence of Mycoplasma genitalium and other sexually transmitted infections causing urethritis among high-risk heterosexual male patients in Estonia","volume":"50","author":"Tjagur","year":"2018","journal-title":"Infect Dis (Lond)"},{"key":"10.1016\/j.ijid.2025.108228_bib0023","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.cmi.2017.09.006","article-title":"Clinical and analytical evaluation of the new Aptima Mycoplasma genitalium assay, with data on M. genitalium prevalence and antimicrobial resistance in M. genitalium in Denmark, Norway and Sweden in 2016","volume":"24","author":"Unemo","year":"2018","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.ijid.2025.108228_bib0024","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1111\/jdv.17972","article-title":"2021 European guideline on the management of Mycoplasma genitalium infections","volume":"36","author":"Jensen","year":"2022","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.ijid.2025.108228_bib0025","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1177\/0956462419825948","article-title":"British Association for Sexual Health and HIV national guideline for the management of infection with Mycoplasma genitalium (2018)","volume":"30","author":"Soni","year":"2019","journal-title":"Int J STD AIDS"},{"key":"10.1016\/j.ijid.2025.108228_bib0026","series-title":"Mycoplasma genitalium: a review of current issues and challenges","author":"Manhart","year":"2017"},{"key":"10.1016\/j.ijid.2025.108228_bib0027","article-title":"Assessing the clinical impact and resource use of a 30-minute chlamydia and gonorrhoea point-of-care test at three sexual health services","volume":"8","author":"Huntington","year":"2021","journal-title":"Ther Adv Infect Dis"},{"key":"10.1016\/j.ijid.2025.108228_bib0028","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1038\/s41598-017-01422-y","article-title":"Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India","volume":"7","author":"Sonkar","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijid.2025.108228_bib0029","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1111\/tmi.12742","article-title":"Evaluation of syndromic management guidelines for treatment of sexually transmitted infections in South African women","volume":"21","author":"van der Eem","year":"2016","journal-title":"Trop Med Int Health"},{"issue":"Suppl 6","key":"10.1016\/j.ijid.2025.108228_bib0030","article-title":"Diagnosing sexually transmitted infections in resource-constrained settings: challenges and ways forward","volume":"22","author":"Wi","year":"2019","journal-title":"J Int AIDS Soc"},{"key":"10.1016\/j.ijid.2025.108228_bib0031","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1097\/OLQ.0000000000001586","article-title":"Clinical integration of a highly accurate polymerase chain reaction point-of-care test can inform immediate treatment decisions for chlamydia, gonorrhea, and trichomonas","volume":"49","author":"Dawkins","year":"2022","journal-title":"Sex Transm Dis"},{"key":"10.1016\/j.ijid.2025.108228_bib0032","first-page":"e00706","article-title":"Sensitivity and specificity of the Cobas Liat CT\/NG\/MG nucleic acid test in a clinical laboratory setting and point-of-care location","author":"Van Der Pol","year":"2025","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijid.2025.108228_bib0033","series-title":"ICH harmonised guideline. Integrated addendum to ICH E6(R1): guideline for good clinical practice E6(R2)","year":"2016"},{"key":"10.1016\/j.ijid.2025.108228_sbref0034","series-title":"Guidance for industry and Food and Drug Administration staff","article-title":"Recommendations for Clinical Laboratory Improvement Amendments of 1988 (CLIA) waiver applications for manufacturers of in vitro diagnostic devices","year":"2020"},{"key":"10.1016\/j.ijid.2025.108228_sbref0035","series-title":"Guidance for Industry and FDA staff","article-title":"Statistical guidance on reporting results from studies evaluating diagnostic tests","year":"2007"},{"key":"10.1016\/j.ijid.2025.108228_bib0036","doi-asserted-by":"crossref","first-page":"e01125","DOI":"10.1128\/JCM.01125-19","article-title":"Molecular testing for Mycoplasma genitalium in the United States: results from the AMES prospective multicenter clinical study","volume":"57","author":"Gaydos","year":"2019","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijid.2025.108228_bib0037","unstructured":"National Institutes of Health. Vaginitis, https:\/\/www.nichd.nih.gov\/health\/topics\/factsheets\/vaginitis [accessed August 2025]."},{"key":"10.1016\/j.ijid.2025.108228_bib0038","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-16302-8","article-title":"Should we screen for the sexually-transmitted infection Mycoplasma genitalium? Evidence synthesis using a transmission-dynamic model","volume":"7","author":"Birger","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijid.2025.108228_bib0039","doi-asserted-by":"crossref","first-page":"S277","DOI":"10.2105\/AJPH.2018.304751","article-title":"Using sexual orientation and gender identity to monitor disparities in HIV, sexually transmitted infections, and viral hepatitis","volume":"108","author":"Shover","year":"2018","journal-title":"Am J Public Health"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971225004503?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971225004503?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T00:33:00Z","timestamp":1773880380000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971225004503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":39,"alternative-id":["S1201971225004503"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2025.108228","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of Mycoplasma genitalium positivity and co-infection with Chlamydia trachomatis and\/or Neisseria gonorrhoeae at various care sites across the United States","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2025.108228","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}],"article-number":"108228"}}