{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T03:47:24Z","timestamp":1784605644173,"version":"3.55.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T00:00:00Z","timestamp":1769558400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["LX22NPO5103"],"award-info":[{"award-number":["LX22NPO5103"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003243","name":"Ministry of Health of the Czech Republic","doi-asserted-by":"publisher","award":["NU21-05-00278"],"award-info":[{"award-number":["NU21-05-00278"]}],"id":[{"id":"10.13039\/501100003243","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.ijid.2026.108444","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:11:29Z","timestamp":1770077489000},"page":"108444","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Clonal relatedness and emerging linezolid resistance in Clostridioides difficile ribotypes 001 and 176 in the Czech Republic"],"prefix":"10.1016","volume":"165","author":[{"given":"Marie","family":"Brajerova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pete","family":"Kinross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elka","family":"Nycova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivana","family":"Vitkov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magda","family":"Balejova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Geigerova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasa","family":"Bartonikova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Tejkalova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Havlinova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iva","family":"Vagnerova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuzana","family":"Kadleckova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lenka","family":"Ryskova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Jezek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Zamazalova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denisa","family":"Vesela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Kucharova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marketa","family":"Skruzna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Curdova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonin","family":"Melichar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Simeckova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"Czy\u017eov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliska","family":"Miskova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tereza","family":"Prokopova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otakar","family":"Nyc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavel","family":"Drevinek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4511-9430","authenticated-orcid":false,"given":"Marcela","family":"Krutova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijid.2026.108444_bib0001","doi-asserted-by":"crossref","DOI":"10.1038\/nrdp.2016.20","article-title":"Clostridium difficile infection","volume":"2","author":"Smits","year":"2016","journal-title":"Nat Rev Dis Primers"},{"issue":"4","key":"10.1016\/j.ijid.2026.108444_bib0002","doi-asserted-by":"crossref","first-page":"dlae112","DOI":"10.1093\/jacamr\/dlae112","article-title":"Antimicrobial susceptibility in Clostridioides difficile varies according to European region and isolate source","volume":"6","author":"Freeman","year":"2024","journal-title":"JAC Antimicrob Resist"},{"issue":"2","key":"10.1016\/j.ijid.2026.108444_bib0003","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/S1473-3099(16)30397-8","article-title":"Effect of a national 4C antibiotic stewardship intervention on the clinical and molecular epidemiology of Clostridium difficile infections in a region of Scotland: a non-linear time-series analysis","volume":"17","author":"Lawes","year":"2017","journal-title":"Lancet Infect Dis"},{"issue":"3","key":"10.1016\/j.ijid.2026.108444_bib0004","doi-asserted-by":"crossref","first-page":"49","DOI":"10.36290\/far.2021.017","article-title":"Anal\u00fdza spot\u0159eby antibiotik v \u010cesk\u00e9 republice a jej\u00ed z\u00e1v\u011bry pro klinickou praxi","volume":"35","author":"Domeck\u00fd","year":"2021","journal-title":"Klin Farmakol Farm"},{"key":"10.1016\/j.ijid.2026.108444_bib0005","series-title":"Antimicrobial consumption in the EU\/EEA (ESAC-Net)\u2014Annual Epidemiological Report 2022","year":"2023"},{"key":"10.1016\/j.ijid.2026.108444_bib0006","series-title":"European Surveillance of Clostridioides (Clostridium) difficile infections. Surveillance protocol version 2.4","year":"2019"},{"issue":"11","key":"10.1016\/j.ijid.2026.108444_bib0007","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1007\/s10096-017-3055-z","article-title":"Increasing incidence of Clostridium difficile ribotype 001 associated with severe course of the infection and previous fluoroquinolone use in the Czech Republic, 2015","volume":"36","author":"Krutova","year":"2017","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"1","key":"10.1016\/j.ijid.2026.108444_bib0008","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/s13756-020-00765-y","article-title":"The association of a reduced susceptibility to moxifloxacin in causative Clostridium (Clostridioides) difficile strain with the clinical outcome of patients","volume":"9","author":"Krutova","year":"2020","journal-title":"Antimicrob Resist Infect Control"},{"key":"10.1016\/j.ijid.2026.108444_bib0009","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.anaerobe.2019.01.005","article-title":"Clostridium difficile isolates derived from Czech horses are resistant to enrofloxacin; cluster to clades 1 and 5 and ribotype 033 predominates","volume":"56","author":"Kecerova","year":"2019","journal-title":"Anaerobe"},{"issue":"6","key":"10.1016\/j.ijid.2026.108444_bib0010","doi-asserted-by":"crossref","first-page":"901","DOI":"10.3390\/microorganisms8060901","article-title":"The colonisation of calves in Czech large-scale dairy farms by clonally-related Clostridioides difficile of the sequence type 11 represented by ribotypes 033 and 126","volume":"8","author":"Masarikova","year":"2020","journal-title":"Microorganisms"},{"issue":"4","key":"10.1016\/j.ijid.2026.108444_bib0011","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00806-22","article-title":"Detection of plasmid-mediated resistance to metronidazole in Clostridioides difficile from river water","volume":"10","author":"Cizek","year":"2022","journal-title":"Microbiol Spectr"},{"issue":"2","key":"10.1016\/j.ijid.2026.108444_bib0012","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0118150","article-title":"Development and validation of an internationally-standardized, high-resolution capillary gel-based electrophoresis PCR-ribotyping protocol for Clostridium difficile","volume":"10","author":"Fawley","year":"2015","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.ijid.2026.108444_bib0013","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1111\/j.1469-0691.2008.02092.x","article-title":"New multiplex PCR method for the detection of Clostridium difficile toxin A (tcdA) and toxin B (tcdB) and the binary toxin (cdtA\/cdtB) genes applied to a Danish strain collection","volume":"14","author":"Persson","year":"2008","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.ijid.2026.108444_bib0014","doi-asserted-by":"crossref","first-page":"8365","DOI":"10.1038\/srep08365","article-title":"RASTtk: a modular and extensible implementation of the RAST algorithm for building custom annotation pipelines and annotating batches of genomes","volume":"5","author":"Brettin","year":"2015","journal-title":"Sci Rep"},{"issue":"4","key":"10.1016\/j.ijid.2026.108444_bib0015","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1128\/JCM.06094-11","article-title":"Multilocus sequence typing of total-genome-sequenced bacteria","volume":"50","author":"Larsen","year":"2012","journal-title":"J Clin Microbiol"},{"issue":"8","key":"10.1016\/j.ijid.2026.108444_bib0016","article-title":"A publicly accessible database for Clostridioides difficile genome sequences supports tracing of transmission chains and epidemics","volume":"6","author":"Frentrup","year":"2020","journal-title":"Microb Genom"},{"issue":"2","key":"10.1016\/j.ijid.2026.108444_bib0017","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.01737-21","article-title":"Comparison of whole-genome sequence-based methods and PCR ribotyping for subtyping of Clostridioides difficile","volume":"60","author":"Baktash","year":"2022","journal-title":"J Clin Microbiol"},{"issue":"12","key":"10.1016\/j.ijid.2026.108444_bib0018","doi-asserted-by":"crossref","first-page":"3491","DOI":"10.1093\/jac\/dkaa345","article-title":"ResFinder 4.0 for predictions of phenotypes from genotypes","volume":"75","author":"Bortolaia","year":"2020","journal-title":"J Antimicrob Chemother"},{"issue":"11","key":"10.1016\/j.ijid.2026.108444_bib0019","doi-asserted-by":"crossref","first-page":"3418","DOI":"10.1128\/AAC.46.11.3418-3421.2002","article-title":"gyrA and gyrB mutations are implicated in cross-resistance to ciprofloxacin and moxifloxacin in Clostridium difficile","volume":"46","author":"Dridi","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"issue":"8","key":"10.1016\/j.ijid.2026.108444_bib0020","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1128\/AAC.00342-08","article-title":"Rifampin and rifaximin resistance in clinical isolates of Clostridium difficile","volume":"52","author":"O'Connor","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"10.1016\/j.ijid.2026.108444_bib0021","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.00243-23","article-title":"Penicillin binding protein substitutions cooccur with fluoroquinolone resistance in epidemic lineages of multidrug-resistant Clostridioides difficile","volume":"14","author":"Dingle","year":"2023","journal-title":"mBio"},{"issue":"1","key":"10.1016\/j.ijid.2026.108444_bib0022","doi-asserted-by":"crossref","first-page":"4130","DOI":"10.1038\/s41467-023-39429-x","article-title":"Decoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile","volume":"14","author":"Olaitan","year":"2023","journal-title":"Nat Commun"},{"key":"10.1016\/j.ijid.2026.108444_bib0023","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1186\/s13059-015-0849-0","article-title":"Circlator: automated circularization of genome assemblies using long sequencing reads","volume":"16","author":"Hunt","year":"2015","journal-title":"Genome Biol"},{"issue":"7","key":"10.1016\/j.ijid.2026.108444_bib0024","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1093\/bioinformatics\/btr039","article-title":"Easyfig: a genome comparison visualizer","volume":"27","author":"Sullivan","year":"2011","journal-title":"Bioinformatics"},{"issue":"3","key":"10.1016\/j.ijid.2026.108444_bib0025","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.plasmid.2008.08.001","article-title":"Revised nomenclature for transposable genetic elements","volume":"60","author":"Roberts","year":"2008","journal-title":"Plasmid"},{"key":"10.1016\/j.ijid.2026.108444_bib0026","unstructured":"European Committee on. Antimicrobial Susceptibility Testing (EUCAST), version 13.1, http:\/\/www.eucast.org\/."},{"key":"10.1016\/j.ijid.2026.108444_bib0027","unstructured":"Clinical and Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing. 33rd edn; M100. 2023."},{"issue":"1","key":"10.1016\/j.ijid.2026.108444_bib0028","doi-asserted-by":"crossref","DOI":"10.1080\/22221751.2025.2482698","article-title":"Genomic islands and molecular mechanisms relating to drug-resistance in Clostridioides (Clostridium) difficile PCR ribotype 176","volume":"14","author":"Krutova","year":"2025","journal-title":"Emerg Microbes Infect"},{"issue":"1","key":"10.1016\/j.ijid.2026.108444_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijantimicag.2023.106824","article-title":"Clostridioides difficile infections were predominantly driven by fluoroquinolone-resistant Clostridioides difficile ribotypes 176 and 001 in Slovakia in 2018-2019","volume":"62","author":"Plankaova","year":"2023","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.ijid.2026.108444_bib0030","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.jgar.2021.07.010","article-title":"Detection of cfr(B)-carrying clinical Enterococcus faecium in China","volume":"26","author":"Cui","year":"2021","journal-title":"J Glob Antimicrob Resist"},{"key":"10.1016\/j.ijid.2026.108444_sbref0031","series-title":"Clostridioides (Clostridium) difficile infections\u2014Annual Epidemiological Report for 2016\u20132017","year":"2022"},{"issue":"3","key":"10.1016\/j.ijid.2026.108444_bib0032","doi-asserted-by":"crossref","first-page":"299","DOI":"10.3390\/antibiotics10030299","article-title":"Mortality following Clostridioides difficile infection in Europe: a retrospective multicenter case-control study","volume":"10","author":"Czepiel","year":"2021","journal-title":"Antibiotics"},{"issue":"12","key":"10.1016\/j.ijid.2026.108444_bib0033","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/S1473-3099(14)70991-0","article-title":"Underdiagnosis of Clostridium difficile across Europe: the European, multicentre, prospective, biannual, point-prevalence study of Clostridium difficile infection in hospitalised patients with diarrhoea (EUCLID)","volume":"14","author":"Davies","year":"2014","journal-title":"Lancet Infect Dis"},{"issue":"7","key":"10.1016\/j.ijid.2026.108444_bib0034","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1093\/cid\/ciy252","article-title":"Two distinct patterns of Clostridium difficile diversity across Europe indicating contrasting routes of spread","volume":"67","author":"Eyre","year":"2018","journal-title":"Clin Infect Dis."},{"issue":"8","key":"10.1016\/j.ijid.2026.108444_bib0035","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1007\/s10096-015-2407-9","article-title":"The emergence of Clostridium difficile PCR-ribotype 001 in Slovakia","volume":"34","author":"Nyc","year":"2015","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.ijid.2026.108444_bib0036","doi-asserted-by":"crossref","DOI":"10.1016\/j.anaerobe.2022.102548","article-title":"Implementation of a Clostridioides difficile sentinel surveillance system in Germany: first insights for 2019-2021","volume":"77","author":"Abdrabou","year":"2022","journal-title":"Anaerobe"},{"key":"10.1016\/j.ijid.2026.108444_bib0037","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2025.1644051","article-title":"Dominance of toxigenic Clostridioides difficile strains and the appearance of the emerging PCR ribotype 955 in hospitals in Silesia, Poland","volume":"16","author":"Szarek","year":"2025","journal-title":"Front Microbiol."},{"issue":"21","key":"10.1016\/j.ijid.2026.108444_bib0038","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2025.30.21.2400675","article-title":"Newly emerging metronidazole-resistant Clostridioides difficile PCR ribotype 955 identified in Poland, 2021 to 2023 but not in Czechia, 2012 to 2023 and Slovakia, 2015 to 2023","volume":"30","author":"Zikova","year":"2025","journal-title":"Euro Surveill"},{"issue":"1","key":"10.1016\/j.ijid.2026.108444_bib0039","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/ng.2478","article-title":"Emergence and global spread of epidemic healthcare-associated Clostridium difficile","volume":"45","author":"He","year":"2013","journal-title":"Nat Genet"},{"issue":"12","key":"10.1016\/j.ijid.2026.108444_bib0040","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1007\/s10096-021-04311-5","article-title":"Antimicrobial resistance in Clostridioides difficile","volume":"40","author":"O'Grady","year":"2021","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.ijid.2026.108444_bib0041","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.drup.2018.10.002","article-title":"Update on prevalence and mechanisms of resistance to linezolid, tigecycline and daptomycin in enterococci in Europe: towards a common nomenclature","volume":"40","author":"Bender","year":"2018","journal-title":"Drug Resist Updat"},{"issue":"5","key":"10.1016\/j.ijid.2026.108444_bib0042","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.01576-23","article-title":"Closing the gap: Oxford Nanopore Technologies R10 sequencing allows comparable results to Illumina sequencing for SNP-based outbreak investigation of bacterial pathogens","volume":"62","author":"Bogaerts","year":"2024","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijid.2026.108444_bib0043","doi-asserted-by":"crossref","DOI":"10.1016\/j.anaerobe.2022.102518","article-title":"Clostridioides difficile infection (CDI) during the COVID-19 pandemic","volume":"74","author":"Spigaglia","year":"2022","journal-title":"Anaerobe"},{"key":"10.1016\/j.ijid.2026.108444_bib0044","article-title":"Comparison of trends in Clostridioides difficile infections in hospitalised patients during the first and second waves of the COVID-19 pandemic: a retrospective sentinel surveillance study","volume":"19","author":"Vendrik","year":"2022","journal-title":"Lancet Reg Health Eur"},{"issue":"8","key":"10.1016\/j.ijid.2026.108444_bib0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0023014","article-title":"Genetic organisation, mobility and predicted functions of genes on integrated, mobile genetic elements in sequenced strains of Clostridium difficile","volume":"6","author":"Brouwer","year":"2011","journal-title":"PLoS One"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971226000792?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971226000792?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T04:20:10Z","timestamp":1777609210000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971226000792"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":45,"alternative-id":["S1201971226000792"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2026.108444","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clonal relatedness and emerging linezolid resistance in Clostridioides difficile ribotypes 001 and 176 in the Czech Republic","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2026.108444","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}],"article-number":"108444"}}