{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T21:12:32Z","timestamp":1778101952695,"version":"3.51.4"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T00:00:00Z","timestamp":1774051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2025YFE0206700"],"award-info":[{"award-number":["2025YFE0206700"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013076","name":"National Major Science and Technology Projects of China","doi-asserted-by":"publisher","award":["2025ZD01907900"],"award-info":[{"award-number":["2025ZD01907900"]}],"id":[{"id":"10.13039\/501100013076","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"publisher","award":["25270G1001"],"award-info":[{"award-number":["25270G1001"]}],"id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.ijid.2026.108587","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T01:09:05Z","timestamp":1774487345000},"page":"108587","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Emergence of Rv0678 (mmpR5) mutations mediating resistance to bedaquiline and clofazimine in a liver transplant recipient with rifampicin-susceptible tuberculosis: A case report"],"prefix":"10.1016","volume":"167","author":[{"given":"Jin","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaomin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiuxin","family":"Qu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenjie","family":"Lai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuxiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuelin","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuihua","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mutong","family":"Fang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.ijid.2026.108587_bib0001","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.13259","article-title":"Mycobacterium tuberculosis after solid organ transplantation: a review of more than 2000 cases","volume":"32","author":"Abad","year":"2018","journal-title":"Clin Transplant"},{"issue":"4","key":"10.1016\/j.ijid.2026.108587_bib0002","doi-asserted-by":"crossref","DOI":"10.1111\/tid.14088","article-title":"Multi-drug resistant and rifampin-resistant tuberculosis in transplant recipients","volume":"25","author":"Abad","year":"2023","journal-title":"Transpl Infect Dis"},{"issue":"25","key":"10.1016\/j.ijid.2026.108587_bib0003","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1056\/NEJMoa2117166","article-title":"A 24-week, all-oral regimen for rifampin-resistant tuberculosis","volume":"387","author":"Nyang'wa","year":"2022","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijid.2026.108587_bib0004","unstructured":"WHO consolidated guidelines on tuberculosis: module 4: treatment and care. World Health Organization: geneva, 2025; ISBN:978-92-4-010814-1."},{"issue":"10","key":"10.1016\/j.ijid.2026.108587_bib0005","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/S1473-3099(25)00151-3","article-title":"Efficacy and safety of 8-week regimens for the treatment of rifampicin-susceptible pulmonary tuberculosis (TRUNCATE-TB): a prespecified exploratory analysis of a multi-arm, multi-stage, open-label, randomised controlled trial","volume":"25","author":"Paton","year":"2025","journal-title":"Lancet Infect Dis"},{"issue":"12","key":"10.1016\/j.ijid.2026.108587_bib0006","doi-asserted-by":"crossref","first-page":"e972","DOI":"10.1016\/S2666-5247(23)00172-6","article-title":"Bedaquiline resistance in patients with drug-resistant tuberculosis in Cape Town, South Africa: a retrospective longitudinal cohort study","volume":"4","author":"Derendinger","year":"2023","journal-title":"Lancet Microbe"},{"issue":"1","key":"10.1016\/j.ijid.2026.108587_bib0007","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1186\/s12879-025-11067-2","article-title":"Prevalence of bedaquiline resistance in patients with drug-resistant tuberculosis: a systematic review and meta-analysis","volume":"25","author":"Hu","year":"2025","journal-title":"BMC Infect Dis"},{"issue":"5","key":"10.1016\/j.ijid.2026.108587_bib0008","doi-asserted-by":"crossref","first-page":"e358","DOI":"10.1016\/S2666-5247(23)00002-2","article-title":"Bedaquiline and clofazimine resistance in Mycobacterium tuberculosis: an in-vitro and in-silico data analysis","volume":"4","author":"Sonnenkalb","year":"2023","journal-title":"Lancet Microbe"},{"issue":"1","key":"10.1016\/j.ijid.2026.108587_bib0009","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1093\/jac\/dkae405","article-title":"In vitro monitoring of drug resistance emergence during stepwise induction of bedaquiline and clofazimine, alone and in combination: a phenotypic and genotypic analysis","volume":"80","author":"Chen","year":"2025","journal-title":"J Antimicrob Chemother"},{"issue":"7","key":"10.1016\/j.ijid.2026.108587_bib0010","doi-asserted-by":"crossref","DOI":"10.1128\/aac.01532-22","article-title":"Bedquiline resistance mutations: correlations with drug exposures and impact on the proteome in M. tuberculosis","volume":"67","author":"Xu","year":"2023","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"10.1016\/j.ijid.2026.108587_bib0011","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00621-2021","article-title":"Emergence of bedaquiline resistance in a high tuberculosis burden country","volume":"59","author":"Chesov","year":"2022","journal-title":"Eur Respir J"},{"key":"10.1016\/j.ijid.2026.108587_bib0012","article-title":"Role of therapeutic drug monitoring in the treatment of multi-drug resistant tuberculosis","volume":"36","author":"Maranchick","year":"2024","journal-title":"J Clin Tuberc Other Mycobact Dis"},{"issue":"12","key":"10.1016\/j.ijid.2026.108587_bib0013","doi-asserted-by":"crossref","first-page":"e964","DOI":"10.1016\/S2666-5247(23)00321-X","article-title":"Emerging bedaquiline-resistant tuberculosis","volume":"4","author":"Lange","year":"2023","journal-title":"Lancet Microbe"},{"issue":"12","key":"10.1016\/j.ijid.2026.108587_bib0014","doi-asserted-by":"crossref","DOI":"10.1084\/jem.20250460","article-title":"Human CD4+ T cells recognize mycobacterium tuberculosis-infected macrophages amid broader responses","volume":"222","author":"Stetsenko","year":"2025","journal-title":"J Exp Med"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971226002225?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971226002225?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T20:27:05Z","timestamp":1778099225000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971226002225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":14,"alternative-id":["S1201971226002225"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2026.108587","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Emergence of Rv0678 (mmpR5) mutations mediating resistance to bedaquiline and clofazimine in a liver transplant recipient with rifampicin-susceptible tuberculosis: A case report","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2026.108587","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}],"article-number":"108587"}}