{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T18:57:21Z","timestamp":1781463441924,"version":"3.54.1"},"reference-count":18,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T00:00:00Z","timestamp":1775779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.ijid.2026.108707","type":"journal-article","created":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T17:38:33Z","timestamp":1776015513000},"page":"108707","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Attenuated clinical presentation but severe laboratory evolution: a longitudinal analysis of dengue infection in older adults hospitalized in Northern Vietnam"],"prefix":"10.1016","volume":"168","author":[{"given":"Dang Thi","family":"Bich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tran Thi","family":"Hoan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1957-8529","authenticated-orcid":false,"given":"Le Xuan","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nguyen Kim","family":"Thu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.ijid.2026.108707_bib0001","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1016\/S1473-3099(20)30601-0","article-title":"Risk predictors of progression to severe disease during the febrile phase of dengue: a systematic review and meta-analysis","volume":"21","author":"Sangkaew","year":"2021","journal-title":"Lancet Infect Dis"},{"issue":"8","key":"10.1016\/j.ijid.2026.108707_bib0002","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0011537","article-title":"Direct and indirect effects of age on dengue severity: the mediating role of secondary infection","volume":"17","author":"Annan","year":"2023","journal-title":"PLOS Negl Trop Dis"},{"issue":"8","key":"10.1016\/j.ijid.2026.108707_bib0003","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.3201\/eid2908.230014","article-title":"Advanced age and increased risk for severe outcomes of dengue infection, Taiwan, 2014\u20132015","volume":"29","author":"Huang","year":"2023","journal-title":"Emerg Infect Dis"},{"issue":"8","key":"10.1016\/j.ijid.2026.108707_bib0004","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1080\/14787210.2017.1358610","article-title":"Dengue in the elderly: a review","volume":"15","author":"Lin","year":"2017","journal-title":"Expert Rev Anti-infect Ther"},{"issue":"4","key":"10.1016\/j.ijid.2026.108707_bib0005","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0002777","article-title":"Challenges in dengue fever in the elderly: atypical presentation and risk of severe dengue and hospita-acquired infection","volume":"8","author":"Rowe","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"issue":"1","key":"10.1016\/j.ijid.2026.108707_bib0006","doi-asserted-by":"crossref","DOI":"10.1038\/srep39872","article-title":"Diabetes, cardiac disorders and asthma as risk factors for severe organ involvement among adult dengue patients: a matched case-control study","volume":"7","author":"Pang","year":"2017","journal-title":"Sci Rep"},{"issue":"9","key":"10.1016\/j.ijid.2026.108707_bib0007","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1093\/trstmh\/traa043","article-title":"Prevalence and clinical manifestations of dengue in older patients in Bangkok hospital for tropical diseases, Thailand","volume":"114","author":"Chhong","year":"2020","journal-title":"Trans R Soc Trop Med Hyg"},{"issue":"37","key":"10.1016\/j.ijid.2026.108707_bib0008","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000007878","article-title":"Predicting the mortality in geriatric patients with dengue fever","volume":"96","author":"Huang","year":"2017","journal-title":"Medicine"},{"issue":"6","key":"10.1016\/j.ijid.2026.108707_bib0009","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0008199","article-title":"Multivariate time-series analysis of biomarkers from a dengue cohort offers new approaches for diagnosis and prognosis","volume":"14","author":"Vasey","year":"2020","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.ijid.2026.108707_bib0010","article-title":"Dengue viremia kinetics and effects on platelet count and clinical outcomes: an analysis of 2340 patients from Vietnam","volume":"13","author":"Vuong","year":"2024","journal-title":"Life"},{"issue":"6","key":"10.1016\/j.ijid.2026.108707_bib0011","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.4269\/ajtmh.14-0472","article-title":"Dengue in adults admitted to a referral hospital in Hanoi, Vietnam","volume":"92","author":"Taylor","year":"2015","journal-title":"Am J Trop Med Hyg"},{"issue":"1","key":"10.1016\/j.ijid.2026.108707_bib0012","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofae753","article-title":"Epidemiology and genotype dynamics of dengue in hospitalized patients in Northern Vietnam between 2020 and 2022","volume":"12","author":"Anh","year":"2025","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.ijid.2026.108707_bib0013","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2025.1600999","article-title":"Dysregulated immune cell responses in severe dengue pathogenesis","volume":"16","author":"Yoo","year":"2025","journal-title":"Front Immunol"},{"issue":"1","key":"10.1016\/j.ijid.2026.108707_bib0014","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.bjid.2012.08.020","article-title":"Comparison of clinical and laboratory characteristics between children and adults with dengue","volume":"17","author":"de Souza","year":"2013","journal-title":"Braz J Infect Dis"},{"issue":"4","key":"10.1016\/j.ijid.2026.108707_bib0015","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s40264-023-01390-5","article-title":"Drug-induced liver injury in the elderly: consensus statements and recommendations from the IQ-DILI initiative","volume":"47","author":"Cohen","year":"2024","journal-title":"Drug Saf"},{"issue":"1","key":"10.1016\/j.ijid.2026.108707_bib0016","doi-asserted-by":"crossref","DOI":"10.5501\/wjv.v13.i1.91457","article-title":"Dengue induced acute liver failure: a meta summary of case reports","volume":"13","author":"Juneja","year":"2024","journal-title":"World J Virol"},{"issue":"4","key":"10.1016\/j.ijid.2026.108707_bib0017","doi-asserted-by":"crossref","DOI":"10.1002\/rmv.2564","article-title":"Liver involvement in dengue: a systematic review","volume":"34","author":"Campana","year":"2024","journal-title":"Rev Med Virol"},{"issue":"4","key":"10.1016\/j.ijid.2026.108707_bib0018","doi-asserted-by":"crossref","first-page":"537","DOI":"10.3390\/medicina60040537","article-title":"Frailty in older adults with dengue fever","volume":"60","author":"Hu","year":"2024","journal-title":"Medicina"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971226003425?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971226003425?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T18:20:43Z","timestamp":1781461243000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971226003425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":18,"alternative-id":["S1201971226003425"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2026.108707","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Attenuated clinical presentation but severe laboratory evolution: a longitudinal analysis of dengue infection in older adults hospitalized in Northern Vietnam","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2026.108707","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}],"article-number":"108707"}}