{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T12:38:47Z","timestamp":1793709527627,"version":"4.6.1"},"reference-count":24,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:00:00Z","timestamp":1790035200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijidonline.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Infectious Diseases"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.ijid.2026.109137","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:26:50Z","timestamp":1790206010000},"page":"109137","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Age- and site-dependent pathogens in spondylodiscitis: a study of 10,801 cases"],"prefix":"10.1016","volume":"173","author":[{"given":"Nicolas Heinz","family":"von der Hoeh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Ardelt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Max Joseph","family":"Scheyerer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Herren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sigmund","family":"Lang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.ijid.2026.109137_bib0001","doi-asserted-by":"crossref","DOI":"10.3390\/jcm12103373","article-title":"The epidemiology of spondylodiscitis in Germany: a descriptive report of incidence rates, pathogens, In-hospital mortality, and hospital stays between 2010 and 2020","volume":"12","author":"Lang","year":"2023","journal-title":"J Clin Med"},{"issue":"1","key":"10.1016\/j.ijid.2026.109137_bib0002","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-023-47341-z","article-title":"Epidemiological trends of pyogenic spondylodiscitis in Germany: an EANS spine Section study","volume":"13","author":"Kramer","year":"2023","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijid.2026.109137_bib0003","doi-asserted-by":"crossref","DOI":"10.3389\/fsurg.2024.1357318","article-title":"Midterm survival and risk factor analysis in patients with pyogenic vertebral osteomyelitis: a retrospective study of 155 cases","volume":"11","author":"Schindler","year":"2024","journal-title":"Front Surg"},{"issue":"5","key":"10.1016\/j.ijid.2026.109137_bib0004","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/j.spinee.2024.12.018","article-title":"Management of severe pyogenic spinal infections: the 2SICK study by the EANS spine section","volume":"25","author":"Kramer","year":"2025","journal-title":"Spine J"},{"issue":"2","key":"10.1016\/j.ijid.2026.109137_bib0005","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0211888","article-title":"Selection of an appropriate empiric antibiotic regimen in hematogenous vertebral osteomyelitis","volume":"14","author":"Park","year":"2019","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.ijid.2026.109137_bib0006","doi-asserted-by":"crossref","DOI":"10.1093\/cid\/civ633","article-title":"2015 Infectious Diseases Society of America (IDSA) clinical practice guidelines for the diagnosis and treatment of native vertebral osteomyelitis in adults","volume":"61","author":"Berbari","year":"2015","journal-title":"Clin Infect Dis"},{"issue":"9971","key":"10.1016\/j.ijid.2026.109137_bib0007","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1016\/S0140-6736(14)61233-2","article-title":"Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial","volume":"385","author":"Bernard","year":"2015","journal-title":"Lancet"},{"issue":"10","key":"10.1016\/j.ijid.2026.109137_bib0008","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1007\/s00256-018-3006-5","article-title":"Culture yield of repeat percutaneous image-guided biopsy after a negative initial biopsy in suspected spondylodiscitis: a systematic review","volume":"47","author":"Kasalak","year":"2018","journal-title":"Skeletal Radiol"},{"issue":"1","key":"10.1016\/j.ijid.2026.109137_bib0009","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1097\/CORR.0000000000001866","article-title":"Treatment guideline for patients with native culture-negative pyogenic vertebral osteomyelitis","volume":"480","author":"Lee","year":"2022","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.ijid.2026.109137_bib0010","first-page":"149","article-title":"Large increase of vertebral osteomyelitis in France: a 2010\u20132019 cross-sectional study","author":"Conan","year":"2021","journal-title":"Epidemiol Infect"},{"issue":"1 Suppl","key":"10.1016\/j.ijid.2026.109137_bib0011","doi-asserted-by":"crossref","first-page":"73S","DOI":"10.1177\/21925682221121300","article-title":"Spondylodiscitis in geriatric patients: what are the issues?","volume":"13","author":"Herren","year":"2023","journal-title":"Global Spine J"},{"issue":"11","key":"10.1016\/j.ijid.2026.109137_bib0012","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1056\/NEJMcp0910753","article-title":"Vertebral osteomyelitis","volume":"362","author":"Zimmerli","year":"2010","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.ijid.2026.109137_bib0013","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.semarthrit.2008.03.002","article-title":"Pyogenic vertebral osteomyelitis: a systematic review of clinical characteristics","volume":"39","author":"Mylona","year":"2009","journal-title":"Semin Arthritis Rheum"},{"issue":"7","key":"10.1016\/j.ijid.2026.109137_bib0014","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1007\/s00132-022-04240-x","article-title":"Aktuelle praxis der empirischen antibiotikatherapie bei spondylodiszitis","volume":"51","author":"Lang","year":"2022","journal-title":"Orthop\u00e4die (Heidelb)"},{"key":"10.1016\/j.ijid.2026.109137_bib0015","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.wneu.2020.10.004","article-title":"Revisiting the vertebral venous plexus\u2014a comprehensive review of the literature","volume":"145","author":"Carpenter","year":"2021","journal-title":"World Neurosurg"},{"issue":"1","key":"10.1016\/j.ijid.2026.109137_bib0016","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0030-5898(20)32045-9","article-title":"Microbiology and antimicrobial therapy of spinal infections","volume":"27","author":"Sapico","year":"1996","journal-title":"Orthop Clin North Am"},{"issue":"6","key":"10.1016\/j.ijid.2026.109137_bib0017","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofaa176","article-title":"Microbial etiology of pyogenic vertebral osteomyelitis according to patient characteristics","volume":"7","author":"Kim","year":"2020","journal-title":"Open Forum Infect Dis"},{"issue":"14","key":"10.1016\/j.ijid.2026.109137_bib0018","doi-asserted-by":"crossref","first-page":"4805","DOI":"10.3390\/jcm12144805","article-title":"Risk factors for the in-hospital mortality in pyogenic vertebral osteomyelitis: a cross-sectional study on 9753 patients","volume":"12","author":"Ziarko","year":"2023","journal-title":"J Clin Med"},{"key":"10.1016\/j.ijid.2026.109137_bib0019","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.ijid.2020.07.028","article-title":"Impact of the localization on disease course and clinical management in spondylodiscitis","volume":"99","author":"Stangenberg","year":"2020","journal-title":"Int J Infect Dis"},{"issue":"3","key":"10.1016\/j.ijid.2026.109137_bib0020","doi-asserted-by":"crossref","first-page":"660","DOI":"10.3390\/jcm11030660","article-title":"The Hamburg spondylodiscitis assessment score (HSAS) for immediate evaluation of mortality risk on hospital admission","volume":"11","author":"Heuer","year":"2022","journal-title":"J Clin Med"},{"issue":"4","key":"10.1016\/j.ijid.2026.109137_bib0021","doi-asserted-by":"crossref","first-page":"830","DOI":"10.3390\/microorganisms9040830","article-title":"Update on coagulase-negative Staphylococci\u2014what the clinician should know","volume":"9","author":"Michels","year":"2021","journal-title":"Microorganisms."},{"issue":"1","key":"10.1016\/j.ijid.2026.109137_bib0022","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1186\/s12879-017-2783-0","article-title":"Characteristics of spontaneous coagulase-negative staphylococcal spondylodiscitis: a retrospective comparative study versus Staphylococcus aureus spondylodiscitis","volume":"17","author":"Lopez","year":"2017","journal-title":"BMC Infect Dis"},{"issue":"11","key":"10.1016\/j.ijid.2026.109137_bib0023","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.3390\/antibiotics10111410","article-title":"Is there a difference in clinical features, microbiological epidemiology and effective empiric antimicrobial therapy comparing healthcare-associated and community-acquired vertebral osteomyelitis?","volume":"10","author":"Lang","year":"2021","journal-title":"Antibiotics (Basel)"},{"issue":"5","key":"10.1016\/j.ijid.2026.109137_bib0024","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1007\/s15010-021-01642-5","article-title":"Influence of microbiological diagnosis on the clinical course of spondylodiscitis","volume":"49","author":"Stangenberg","year":"2021","journal-title":"Infection"}],"container-title":["International Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971226007721?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1201971226007721?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T12:19:25Z","timestamp":1793708365000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1201971226007721"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":24,"alternative-id":["S1201971226007721"],"URL":"https:\/\/doi.org\/10.1016\/j.ijid.2026.109137","relation":{},"ISSN":["1201-9712"],"issn-type":[{"value":"1201-9712","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Age- and site-dependent pathogens in spondylodiscitis: a study of 10,801 cases","name":"articletitle","label":"Article Title"},{"value":"International Journal of Infectious Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijid.2026.109137","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}],"article-number":"109137"}}