{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T11:10:14Z","timestamp":1793185814906,"version":"4.5.0"},"reference-count":117,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["DI 931\/3-1"],"award-info":[{"award-number":["DI 931\/3-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005687","name":"Goethe-Universit\u00e4t Frankfurt am Main","doi-asserted-by":"publisher","award":["EXC115"],"award-info":[{"award-number":["EXC115"]}],"id":[{"id":"10.13039\/501100005687","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004410","name":"European Molecular Biology Organization","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004410","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Medical Microbiology"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.ijmm.2017.11.003","type":"journal-article","created":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T16:01:32Z","timestamp":1509984092000},"page":"176-184","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"title":["Regulation of Salmonella-host cell interactions via the ubiquitin system"],"prefix":"10.1016","volume":"308","author":[{"given":"Lina","family":"Herhaus","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Dikic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijmm.2017.11.003_bib0005","doi-asserted-by":"crossref","first-page":"16948","DOI":"10.1021\/ja4099643","article-title":"Development of activity-based probes for ubiquitin and ubiquitin-like protein signaling pathways","author":"An","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0010","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/nrmicro3259","article-title":"Exploitation of the host ubiquitin system by human bacterial pathogens","author":"Ashida","year":"2014","journal-title":"Nat. Rev. Microbiol. (Nature Publishing Group)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0015","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.chom.2016.10.007","article-title":"The Salmonella effector SteD mediates MARCH8-dependent ubiquitination of MHC II molecules and inhibits T cell activation","volume":"20","author":"Bayer-Santos","year":"2016","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0020","doi-asserted-by":"crossref","first-page":"27587","DOI":"10.1074\/jbc.M109.010363","article-title":"Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin","author":"Bernal-Bayard","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0025","doi-asserted-by":"crossref","first-page":"16360","DOI":"10.1074\/jbc.M110.100669","article-title":"The Salmonella type III secretion effector, Salmonella leucine-rich repeat protein (SlrP), targets the human chaperone ERdj3","author":"Bernal-Bayard","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0030","doi-asserted-by":"crossref","first-page":"e1003518","DOI":"10.1371\/journal.ppat.1003518","article-title":"The Salmonella type III effector SspH2 specifically exploits the NLR co-chaperone activity of SGT1 to subvert immunity","volume":"9","author":"Bhavsar","year":"2013","journal-title":"PLoS Pathog."},{"issue":"1636\u20131649","key":"10.1016\/j.ijmm.2017.11.003_bib0035","first-page":"e1613","article-title":"Phosphoribosylation of ubiquitin promotes serine ubiquitination and impairs conventional ubiquitination","volume":"167","author":"Bhogaraju","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0040","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1080\/15548627.2016.1203490","article-title":"Unveiling ubiquitinome rearrangements induced by Salmonella infection","volume":"12","author":"Bionda","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0045","doi-asserted-by":"crossref","first-page":"11374","DOI":"10.1074\/jbc.M509157200","article-title":"Autophagy controls salmonella infection in response to damage to the Salmonella-containing vacuole","author":"Birmingham","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0050","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jcmgh.2017.05.002","article-title":"Bacterial autophagy: offense and defense at the host-pathogen interface","volume":"4","author":"Casanova","year":"2017","journal-title":"Cell Mol. Gastroenterol. Hepatol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0055","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1080\/15548627.2016.1191724","article-title":"Autophagy proteins are not universally required for phagosome maturation","volume":"12","author":"Cemma","year":"2016","journal-title":"Autophagy"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0060","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1152\/physrev.00002.2013","article-title":"Deubiquitylases from genes to organism","volume":"93","author":"Clague","year":"2013","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0065","first-page":"686","article-title":"Will the ubiquitin system furnish as many drug targets as protein kinases?","author":"Cohen","year":"2010","journal-title":"Cell (Elsevier Inc.)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0070","doi-asserted-by":"crossref","first-page":"2846","DOI":"10.4049\/jimmunol.169.6.2846","article-title":"Cutting edge: Salmonella AvrA effector inhibits the key proinflammatory, anti-apoptotic NF-kappa B pathway","volume":"169","author":"Collier-Hyams","year":"2002","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0075","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1128\/IAI.00985-06","article-title":"SseL is a salmonella-specific translocated effector integrated into the SsrB-controlled salmonella pathogenicity island 2 type III secretion system","volume":"75","author":"Coombes","year":"2007","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0080","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1016\/j.bbrc.2016.03.014","article-title":"Proteomic insight into the effects of the Salmonella ubiquitin ligase SlrP on host cells","volume":"472","author":"Cordero-Alba","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0085","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1038\/nri3532","article-title":"Autophagy in infection, inflammation and immunity","volume":"13","author":"Deretic","year":"2013","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0090","doi-asserted-by":"crossref","first-page":"e1000595","DOI":"10.1371\/journal.ppat.1000595","article-title":"Selective inhibition of type III secretion activated signaling by the Salmonella effector AvrA","volume":"5","author":"Du","year":"2009","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0095","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3389\/fimmu.2016.00081","article-title":"Modulation of host autophagy during bacterial infection: sabotaging host munitions for pathogen nutrition","volume":"7","author":"Escoll","year":"2016","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0100","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1099\/mic.0.058115-0","article-title":"Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectors","volume":"158","author":"Figueira","year":"2012","journal-title":"Microbiology"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0105","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/j.molcel.2016.04.015","article-title":"Global analysis of host and bacterial ubiquitinome in response to Salmonella typhimurium infection","volume":"62","author":"Fiskin","year":"2016","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0110","doi-asserted-by":"crossref","first-page":"14004","DOI":"10.1038\/ncomms14004","article-title":"Structural basis for the recognition and degradation of host TRIM proteins by Salmonella effector SopA","volume":"8","author":"Fiskin","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0115","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.chom.2016.11.002","article-title":"The ubiquitin ligase smurf1 functions in selective autophagy of mycobacterium tuberculosis and anti-tuberculous host defense","volume":"21","author":"Franco","year":"2017","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0120","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/nature05272","article-title":"Protein delivery into eukaryotic cells by type III secretion machines","author":"Gal\u00e1n","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0125","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.molcel.2014.03.009","article-title":"Autophagy in antimicrobial immunity","volume":"54","author":"Gomes","year":"2014","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0130","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1046\/j.1365-2958.1997.3101672.x","article-title":"Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution","volume":"23","author":"Hacker","year":"1997","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0135","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1111\/j.1462-5822.2005.00670.x","article-title":"A Salmonella type III secretion effector interacts with the mammalian serine\/threonine protein kinase PKN1","author":"Haraga","year":"2006","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0140","doi-asserted-by":"crossref","first-page":"9887","DOI":"10.1073\/pnas.94.18.9887","article-title":"A secreted Salmonella protein with homology to an avirulence determinant of plant pathogenic bacteria","volume":"94","author":"Hardt","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0145","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1016\/j.celrep.2016.11.005","article-title":"RNF166 determines recruitment of adaptor proteins during antibacterial autophagy","volume":"17","author":"Heath","year":"2016","journal-title":"Cell Rep."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmb.2017.08.012","article-title":"LC3-associated phagocytosis and inflammation","author":"Heckmann","year":"2017","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0155","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1046\/j.1365-2958.2000.01935.x","article-title":"Salmonella pathogenicity island 2","volume":"36","author":"Hensel","year":"2000","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0160","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.15252\/embr.201540891","article-title":"Expanding the ubiquitin code through post-translational modification","volume":"16","author":"Herhaus","year":"2015","journal-title":"EMBO Rep."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0165","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1016\/j.cellsig.2014.06.012","article-title":"The emerging roles of deubiquitylating enzymes (DUBs) in the TGFbeta and BMP pathways","volume":"26","author":"Herhaus","year":"2014","journal-title":"Cell. Signal."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0170","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1146\/annurev.biochem.67.1.425","article-title":"The ubiquitin system","volume":"67","author":"Hershko","year":"1998","journal-title":"Annu. Rev. Biochem"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0175","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1038\/nature07958","article-title":"Origin and function of ubiquitin-like proteins","volume":"458","author":"Hochstrasser","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0180","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1089\/154065803321537890","article-title":"Development of a high throughput time-resolved fluorescence resonance energy transfer assay for TRAF6 ubiquitin polymerization","author":"Hong","year":"2003","journal-title":"Assay Drug Dev. Technol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0185","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.chom.2012.10.019","article-title":"The LRR and RING domain protein LRSAM1 is an E3 ligase crucial for ubiquitin-dependent autophagy of intracellular salmonella typhimurium","author":"Huett","year":"2012","journal-title":"Cell Host Microbe (Elsevier Inc.)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0190","doi-asserted-by":"crossref","first-page":"e1004255","DOI":"10.1371\/journal.ppat.1004255","article-title":"Hell's BELs: bacterial E3 ligases that exploit the eukaryotic ubiquitin machinery","volume":"10","author":"Huibregtse","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0195","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1146\/annurev-biochem-051810-094654","article-title":"Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions","volume":"81","author":"Husnjak","year":"2012","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0200","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.chom.2008.02.016","article-title":"Salmonella AvrA coordinates suppression of host immune and apoptotic defenses via JNK pathway blockade","volume":"3","author":"Jones","year":"2008","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0205","doi-asserted-by":"crossref","first-page":"e1005552","DOI":"10.1371\/journal.ppat.1005552","article-title":"The Salmonella effector protein SopA modulates innate immune responses by targeting TRIM E3 ligase family members","author":"Kamanova","year":"2016","journal-title":"PLoS Pathog (Public Library of Science)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0210","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1073\/pnas.1611595114","article-title":"Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases","volume":"114","author":"Keszei","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0215","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1128\/MCB.01360-13","article-title":"Structure of an sspH1-PKN1 complex reveals the basis for host substrate recognition and mechanism of activation for a bacterial E3 ubiquitin ligase","author":"Keszei","year":"2014","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0220","first-page":"1312","article-title":"OTULIN antagonizes LUBAC signaling by specifically hydrolyzing met 1-linked polyubiquitin","author":"Keusekotten","year":"2013","journal-title":"Cell (Elsevier Inc.)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0225","doi-asserted-by":"crossref","first-page":"e84681","DOI":"10.1371\/journal.pone.0084681","article-title":"Quantitative assessment of cytosolic Salmonella in epithelial cells","volume":"9","author":"Knodler","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0230","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.mib.2014.10.010","article-title":"Salmonella enterica: living a double life in epithelial cells","volume":"23","author":"Knodler","year":"2015","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0235","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1038\/nrm2731","article-title":"Breaking the chains: structure and function of the deubiquitinases","volume":"10","author":"Komander","year":"2009","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0240","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/nrmicro3420","article-title":"Salmonellae interactions with host processes","author":"LaRock","year":"2015","journal-title":"Nat. Rev. Microbiol. (Nature Publishing Group)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0245","doi-asserted-by":"crossref","first-page":"5045","DOI":"10.4049\/jimmunol.180.7.5045","article-title":"Salmonella secreted factor L deubiquitinase of Salmonella typhimurium inhibits NF-kappaB, suppresses IkappaBalpha ubiquitination and modulates innate immune responses","volume":"180","author":"Le Negrate","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0250","doi-asserted-by":"crossref","first-page":"ra9","DOI":"10.1126\/scisignal.2003730","article-title":"Sterical hindrance promotes selectivity of the autophagy cargo receptor NDP52 for the danger receptor galectin-8 in antibacterial autophagy","volume":"6","author":"Li","year":"2013","journal-title":"Sci. Signal."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0255","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/nature08357","article-title":"Inhibitors selective for mycobacterial versus human proteasomes","volume":"461","author":"Lin","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0260","doi-asserted-by":"crossref","first-page":"26837","DOI":"10.1074\/jbc.M116.757393","article-title":"Salmonella enteritidis effector AvrA stabilizes intestinal tight junctions via the JNK pathway","volume":"291","author":"Lin","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0265","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1186\/1471-2180-10-326","article-title":"Eukaryotic signaling pathways targeted by Salmonella effector protein AvrA in intestinal infection in vivo","volume":"10","author":"Liu","year":"2010","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0270","first-page":"17023","volume":"vol. 2","author":"Liu","year":"2017"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0275","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.neo.2016.04.001","article-title":"Salmonella protein AvrA activates the STAT3 signaling pathway in colon cancer","volume":"18","author":"Lu","year":"2016","journal-title":"Neoplasia"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0280","doi-asserted-by":"crossref","first-page":"18940","DOI":"10.1038\/srep18940","article-title":"A generic platform for cellular screening against ubiquitin ligases","author":"Maculins","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0285","first-page":"1","article-title":"Bacteria-host relationship: ubiquitin ligases as weapons of invasion","author":"Maculins","year":"2016","journal-title":"Cell Res. (Nature Publishing Group)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0290","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3389\/fmicb.2011.00125","article-title":"Salmonella \u2013 at home in the host cell","volume":"2","author":"Malik-Kale","year":"2011","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0295","doi-asserted-by":"crossref","first-page":"e38732","DOI":"10.1371\/journal.pone.0038732","article-title":"The bimodal lifestyle of intracellular Salmonella in epithelial cells: replication in the cytosol obscures defects in vacuolar replication","volume":"7","author":"Malik-Kale","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0300","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/nature12566","article-title":"The ubiquitin ligase parkin mediates resistance to intracellular pathogens","volume":"501","author":"Manzanillo","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0305","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1038\/ncb3192","article-title":"Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins","volume":"17","author":"Martinez","year":"2015","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0310","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.molcel.2011.07.039","article-title":"Serine 403 phosphorylation of p62\/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins","author":"Matsumoto","year":"2011","journal-title":"Mol. Cell (Elsevier Inc.)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0315","doi-asserted-by":"crossref","first-page":"e1002743","DOI":"10.1371\/journal.ppat.1002743","article-title":"The Salmonella deubiquitinase SseL inhibits selective autophagy of cytosolic aggregates","volume":"8","author":"Mesquita","year":"2012","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0320","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.cell.2014.03.037","article-title":"Enhanced protein degradation by branched ubiquitin chains","volume":"157","author":"Meyer","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0325","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1111\/j.1365-2958.1995.tb02382.x","article-title":"A 40 kb chromosomal fragment encoding Salmonella typhimurium invasion genes is absent from the corresponding region of the Escherichia coli K-12 chromosome","volume":"15","author":"Mills","year":"1995","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0330","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1128\/CMR.00046-08","article-title":"Pathogen recognition and inflammatory signaling in innate immune defenses","volume":"22","author":"Mogensen","year":"2009","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0335","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.bbrc.2010.09.048","article-title":"The bacterial effector Cif interferes with SCF ubiquitin ligase function by inhibiting deneddylation of Cullin1","volume":"401","author":"Morikawa","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0340","doi-asserted-by":"crossref","first-page":"26987","DOI":"10.1074\/jbc.M111.223610","article-title":"p62 and NDP52 proteins target intracytosolic Shigella and Listeria to different autophagy pathways","volume":"286","author":"Mostowy","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0345","doi-asserted-by":"crossref","first-page":"4029","DOI":"10.1021\/acs.jproteome.5b00574","article-title":"Identification of Salmonella typhimurium deubiquitinase SseL substrates by immunoaffinity enrichment and quantitative proteomic analysis","volume":"14","author":"Nakayasu","year":"2015","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0350","doi-asserted-by":"crossref","first-page":"17063","DOI":"10.1038\/nmicrobiol.2017.63","article-title":"LUBAC-synthesized linear ubiquitin chains restrict cytosol-invading bacteria by activating autophagy and NF-kappaB","volume":"2","author":"Noad","year":"2017","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0355","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3389\/fmicb.2011.00143","article-title":"Interactions of bacterial proteins with host eukaryotic ubiquitin pathways","volume":"2","author":"Perrett","year":"2011","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0360","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.cub.2004.04.033","article-title":"Recognition of bacteria in the cytosol of mammalian cells by the ubiquitin system","author":"Perrin","year":"2004","journal-title":"Curr. Biol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0365","doi-asserted-by":"crossref","DOI":"10.15252\/embr.201643851","article-title":"Expanding the host cell ubiquitylation machinery targeting cytosolic Salmonella","author":"Polajnar","year":"2017","journal-title":"EMBO Rep."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0370","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.molcel.2016.06.015","article-title":"The molecular basis for ubiquitin and ubiquitin-like specificities in bacterial effector proteases","volume":"63","author":"Pruneda","year":"2016","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0375","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s40169-017-0154-5","article-title":"Autophagy and inflammation","volume":"6","author":"Qian","year":"2017","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0380","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1038\/nature17657","article-title":"Ubiquitination independent of E1 and E2 enzymes by bacterial effectors","volume":"533","author":"Qiu","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0385","doi-asserted-by":"crossref","first-page":"4864","DOI":"10.1073\/pnas.0811058106","article-title":"A family of Salmonella virulence factors functions as a distinct class of autoregulated E3 ubiquitin ligases","author":"Quezada","year":"2009","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0390","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1016\/j.cell.2009.03.007","article-title":"Specific recognition of linear ubiquitin chains by NEMO is important for NF-κB activation","author":"Rahighi","year":"2009","journal-title":"Cell (Elsevier Ltd)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0395","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.chom.2014.03.012","article-title":"Self and nonself: how autophagy targets mitochondria and bacteria","author":"Randow","year":"2014","journal-title":"Cell Host Microbe (Elsevier Inc.)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0400","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.ceb.2015.08.005","article-title":"Rho GTPase signalling in cell migration","volume":"36","author":"Ridley","year":"2015","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0405","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.chom.2007.02.002","article-title":"Type III secretion effectors of the IpaH family are E3 ubiquitin ligases","author":"Rohde","year":"2007","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0410","doi-asserted-by":"crossref","first-page":"e1203","DOI":"10.1038\/cddis.2014.113","article-title":"High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy","author":"Rossi","year":"2014","journal-title":"Cell Death Dis. (Nature Publishing Group)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0415","first-page":"85","article-title":"Tumor necrosis factor receptor-associated factor 6 (TRAF6) mediates ubiquitination-dependent STAT3 activation upon Salmonella enterica serovar typhimurium infection","author":"Ruan","year":"2017","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0420","doi-asserted-by":"crossref","first-page":"3502","DOI":"10.1073\/pnas.0610095104","article-title":"SseL, a Salmonella deubiquitinase required for macrophage killing and virulence","volume":"104","author":"Rytkonen","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0425","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.tibs.2015.05.002","article-title":"Layers of DUB regulation","volume":"40","author":"Sahtoe","year":"2015","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0430","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1038\/nature06421","article-title":"Toll-like receptor signalling in macrophages links the autophagy pathway to phagocytosis","volume":"450","author":"Sanjuan","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0435","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1038\/nsmb.1511","article-title":"Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases","author":"Singer","year":"2008","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0440","doi-asserted-by":"crossref","DOI":"10.1128\/mSystems.00032-15","article-title":"Identification of novel host interactors of effectors secreted by Salmonella and citrobacter","volume":"1","author":"Sontag","year":"2016","journal-title":"mSystems"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0445","first-page":"4883","article-title":"The ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and contributes to Salmonella resistance in mice","volume":"127","author":"Spinnenhirn","year":"2014","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0450","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1146\/annurev-biophys-051013-022958","article-title":"Structural and functional insights to ubiquitin-like protein conjugation","volume":"43","author":"Streich","year":"2014","journal-title":"Annu. Rev. Biophys."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0455","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.4161\/auto.21742","article-title":"The DUB-ious lack of ALIS in Salmonella infection: a Salmonella deubiquitinase regulates the autophagy of protein aggregates","volume":"8","author":"Thomas","year":"2012","journal-title":"Autophagy"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0460","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1038\/ni.1800","article-title":"The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria","volume":"10","author":"Thurston","year":"2009","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0465","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1038\/nature10744","article-title":"Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion","author":"Thurston","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0470","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/ncb1821","article-title":"Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation","volume":"11","author":"Tokunaga","year":"2009","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0475","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/ni.1823","article-title":"Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry","volume":"11","author":"Travassos","year":"2010","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0480","doi-asserted-by":"crossref","first-page":"e1005174","DOI":"10.1371\/journal.ppat.1005174","article-title":"The autophagy receptor TAX1BP1 and the molecular motor myosin VI are required for clearance of Salmonella typhimurium by autophagy","volume":"11","author":"Tumbarello","year":"2015","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0485","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1146\/annurev-biochem-093010-153308","article-title":"Ubiquitin-like proteins","volume":"81","author":"van der Veen","year":"2012","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0490","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.molcel.2012.08.024","article-title":"LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy","volume":"48","author":"von Muhlinen","year":"2012","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0495","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1146\/annurev-biochem-051910-094049","article-title":"The ubiquitin system, an immense realm","volume":"81","author":"Varshavsky","year":"2012","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0500","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.molcel.2012.06.017","article-title":"Fluorescence-based sensors to monitor localization and functions of linear and K63-linked ubiquitin chains in cells","author":"van Wijk","year":"2012","journal-title":"Mol. Cell (Elsevier Inc.)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0505","doi-asserted-by":"crossref","first-page":"17066","DOI":"10.1038\/nmicrobiol.2017.66","article-title":"Linear ubiquitination of cytosolic Salmonella typhimurium activates NF-kappaB and restricts bacterial proliferation","volume":"2","author":"van Wijk","year":"2017","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0510","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.chom.2015.02.008","article-title":"Autophagy receptor NDP52 regulates pathogen-containing autophagosome maturation","volume":"17","author":"Verlhac","year":"2015","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0515","first-page":"1","article-title":"InTRIMsic immunity: positive and negative regulation of immune signaling by tripartite motif proteins","author":"Versteeg","year":"2014","journal-title":"Cytokine Growth Factor Rev. (Elsevier Ltd)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0520","doi-asserted-by":"crossref","first-page":"21244","DOI":"10.1074\/jbc.R115.675165","article-title":"Regulating the regulators: recent revelations in the control of E3 ubiquitin ligases","volume":"290","author":"Vittal","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0525","series-title":"Salmonella (non-typhoidal)","author":"WHO","year":"2016"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0530","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1126\/science.1205405","article-title":"Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth","volume":"333","author":"Wild","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0535","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1046\/j.1462-5822.2000.00054.x","article-title":"The secreted effector protein of Salmonella dublin, SopA, is translocated into eukaryotic cells and influences the induction of enteritis","author":"Wood","year":"2000","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0540","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.immuni.2007.05.022","article-title":"Toll-like receptor 4 is a sensor for autophagy associated with innate immunity","volume":"27","author":"Xu","year":"2007","journal-title":"Immunity"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0545","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1038\/ncb0910-814","article-title":"Eaten alive: a history of macroautophagy","author":"Yang","year":"2010","journal-title":"Nat. Cell Biol. (Nature Publishing Group)"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0550","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/ncb3358","article-title":"The increasing complexity of the ubiquitin code","volume":"18","author":"Yau","year":"2016","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0555","doi-asserted-by":"crossref","first-page":"882","DOI":"10.2353\/ajpath.2007.070220","article-title":"Salmonella effector AvrA regulation of colonic epithelial cell inflammation by deubiquitination","volume":"171","author":"Ye","year":"2007","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0560","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1111\/j.1365-2958.2006.05407.x","article-title":"The inflammation-associated salmonella SopA is a HECT-like E3 ubiquitin ligase","author":"Zhang","year":"2006","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0565","doi-asserted-by":"crossref","first-page":"e972849","DOI":"10.4161\/21688362.2014.972849","article-title":"Bacterial protein AvrA stabilizes intestinal epithelial tight junctions via blockage of the C-Jun N-terminal kinase pathway","volume":"3","author":"Zhang","year":"2015","journal-title":"Tissue Barriers"},{"key":"10.1016\/j.ijmm.2017.11.003_bib0570","doi-asserted-by":"crossref","first-page":"5909","DOI":"10.4049\/jimmunol.0900441","article-title":"The adaptor protein p62\/SQSTM1 targets invading bacteria to the autophagy pathway","volume":"183","author":"Zheng","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0575","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/cmi.12384","article-title":"Diversity of bacterial manipulation of the host ubiquitin pathways","volume":"17","author":"Zhou","year":"2015","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0580","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1038\/nsmb.1517","article-title":"Structure of a Shigella effector reveals a new class of ubiquitin ligases","author":"Zhu","year":"2008","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.ijmm.2017.11.003_bib0585","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1042\/BJ20140587","article-title":"The structure of the Slrp\u2013Trx1 complex sheds light on the autoinhibition mechanism of the type III secretion system effectors of the NEL family","author":"Zouhir","year":"2014","journal-title":"Biochem. J."}],"container-title":["International Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1438422117302801?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1438422117302801?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T16:58:10Z","timestamp":1761411490000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1438422117302801"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":117,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["S1438422117302801"],"URL":"https:\/\/doi.org\/10.1016\/j.ijmm.2017.11.003","relation":{},"ISSN":["1438-4221"],"issn-type":[{"value":"1438-4221","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Regulation of Salmonella-host cell interactions via the ubiquitin system","name":"articletitle","label":"Article Title"},{"value":"International Journal of Medical Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijmm.2017.11.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}