{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T04:05:22Z","timestamp":1793419522912,"version":"4.5.0"},"reference-count":60,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,3,7]],"date-time":"2020-03-07T00:00:00Z","timestamp":1583539200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Medical Microbiology"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.ijmm.2020.151416","type":"journal-article","created":{"date-parts":[[2020,3,9]],"date-time":"2020-03-09T12:52:45Z","timestamp":1583758365000},"page":"151416","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["The Treponema pallidum outer membrane protein Tp92 activates endothelial cells via the chemerin\/CMKLR1 pathway"],"prefix":"10.1016","volume":"310","author":[{"given":"Rui-Li","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian-Qiu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijmm.2020.151416_bib0005","doi-asserted-by":"crossref","first-page":"12313","DOI":"10.1074\/jbc.M114.629188","article-title":"Bipartite topology of Treponema pallidum repeat proteins C\/D and I: couter membrane insertion, trimerization, and porin function require a C-terminal \u03b2-barrel domain","volume":"290","author":"Anand","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijmm.2020.151416_bib0010","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.cytogfr.2011.11.004","article-title":"Chemerin and its receptors in leukocyte trafficking, inflammation and metabolism","volume":"22","author":"Bondue","year":"2011","journal-title":"Cytokine Growth Factor Rev."},{"key":"10.1016\/j.ijmm.2020.151416_bib0015","doi-asserted-by":"crossref","first-page":"105","DOI":"10.3390\/pathogens2010105","article-title":"The significance of matrix metalloproteinases in parasitic infections involving the central nervous system","volume":"2","author":"Bruschi","year":"2013","journal-title":"Pathogens"},{"key":"10.1016\/j.ijmm.2020.151416_bib0020","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1111\/1556-4029.13709","article-title":"Syphilis-cardiovascular manifestations of the great imitator","volume":"63","author":"Byard","year":"2018","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.ijmm.2020.151416_bib0025","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1086\/315399","article-title":"Opsonic potential, protective capacity, and sequence conservation of the Treponema pallidum subspecies pallidum Tp92","volume":"181","author":"Cameron","year":"2000","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijmm.2020.151416_bib0030","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1084\/jem.20071601","article-title":"Synthetic chemerin-derived peptides suppress inflammation through ChemR23","volume":"205","author":"Cash","year":"2008","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ijmm.2020.151416_bib0035","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1097\/IGC.0000000000000053","article-title":"RhoC mediates invasion and migration of CaSki cells through the Rho-associated serine-threonine protein kinase 1 signaling pathway","volume":"24","author":"Chen","year":"2014","journal-title":"Int. J. Gynecol. Cancer"},{"key":"10.1016\/j.ijmm.2020.151416_bib0040","doi-asserted-by":"crossref","first-page":"5178","DOI":"10.1128\/IAI.00834-10","article-title":"Surface immunolabeling and consensus computational framework to identify candidate rare outer membrane proteins of Treponema pallidum","volume":"8","author":"Cox","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijmm.2020.151416_bib0045","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1111\/j.1365-2958.2011.07662.x","article-title":"TP0326, a Treponema pallidum \u03b2-barrel assembly machinery A (BamA) orthologue and rare outer membrane protein","volume":"80","author":"Desrosiers","year":"2011","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0050","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.2169\/internalmedicine.50.5025","article-title":"Elevated serum chemerin levels are associated with the presence of coronary artery disease in patients with metabolic syndrome","volume":"50","author":"Dong","year":"2011","journal-title":"Intern. Med."},{"key":"10.1016\/j.ijmm.2020.151416_bib0055","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.tem.2010.08.001","article-title":"Chemerin: at the crossroads of inflammation and obesity","volume":"21","author":"Ernst","year":"2010","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.ijmm.2020.151416_bib0060","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.phrs.2015.07.018","article-title":"Chemerin: a comprehensive review elucidating the need for cardiovascular research","volume":"99","author":"Ferland","year":"2015","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.ijmm.2020.151416_bib0065","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0378-1119(95)00049-C","article-title":"The sequencing of the 80-kDa D15 protective surface antigen of Haemophilus influenzae","volume":"156","author":"Flack","year":"1995","journal-title":"Gene"},{"key":"10.1016\/j.ijmm.2020.151416_bib0070","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1111\/j.1365-2958.2005.04906.x","article-title":"Molecular architecture and function of the Omp85 family of proteins","volume":"58","author":"Gentle","year":"2005","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0075","doi-asserted-by":"crossref","first-page":"353","DOI":"10.3389\/fimmu.2017.00353","article-title":"Antimicrobial and attractant roles for chemerin in the oral cavity during inflammatory gum disease","volume":"8","author":"Godlewska","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0080","doi-asserted-by":"crossref","first-page":"28175","DOI":"10.1074\/jbc.M700793200","article-title":"Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism","volume":"282","author":"Goralski","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijmm.2020.151416_bib0085","doi-asserted-by":"crossref","first-page":"6717","DOI":"10.4049\/jimmunol.0803435","article-title":"Chemokine-like receptor-1 expression by central nervous system infiltrating leukocytes and involvement in a model of autoimmune demyelinating disease","volume":"183","author":"Graham","year":"2009","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0090","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1189\/jlb.0508322","article-title":"Role of neutrophil proteinase 3 and mast cell chymase in chemerin proteolytic regulation","volume":"84","author":"Guillabert","year":"2008","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0095","doi-asserted-by":"crossref","first-page":"3728","DOI":"10.4049\/jimmunol.0902154","article-title":"Chemerin contributes to inflammation by promoting macrophage adhesion to VCAM-1 and fibronectin through clustering of VLA-4 and VLA-5","volume":"185","author":"Hart","year":"2010","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0100","doi-asserted-by":"crossref","first-page":"2428","DOI":"10.1128\/IAI.01128-07","article-title":"Highly conserved surface protein of oral spirochetes as adherins and potent inducers of proinflammatory and osteoclastogenic factors","volume":"76","author":"Jun","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijmm.2020.151416_bib0105","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1124\/pr.116.013177","article-title":"International union of basic and clinical pharmacology CIII: chemerin receptors CMKLR1(Chemerin1) and GPR1 (Chemerin2) nomenclature, pharmacology, and function","volume":"70","author":"Kennedy","year":"2018","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ijmm.2020.151416_bib0110","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1471-2261-14-56","article-title":"Chemerin and CMKLR1 expression in human arteries and periadventitial fat: a possible role for local chemerin in atherosclerosis?","volume":"14","author":"Kostopoulos","year":"2014","journal-title":"BMC Cardiovasc. Disord."},{"key":"10.1016\/j.ijmm.2020.151416_bib0115","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jss.2004.12.023","article-title":"Effects of adipocyte-derived cytokines on endothelial functions: implication of vascular disease","volume":"126","author":"Kougias","year":"2005","journal-title":"J. Surg. Res."},{"key":"10.1016\/j.ijmm.2020.151416_bib0120","doi-asserted-by":"crossref","first-page":"e01006","DOI":"10.1128\/mBio.01006-18","article-title":"Sequence variation of rare outer membrane protein \u03b2-Barrel domains in clinical strains provides insights into the evolution of Treponema pallidum subsp. pallidum, the syphilis spirochete","volume":"9","author":"Kumar","year":"2018","journal-title":"MBio"},{"key":"10.1016\/j.ijmm.2020.151416_bib0125","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1177\/2042018816637312","article-title":"Serum chemerin and high-sensitivity C reactive protein as markers of subclinical atherosclerosisin Egyptian patients with type 2 diabetes","volume":"7","author":"Lachine","year":"2016","journal-title":"Ther. Adv. Endocrinol. Metab."},{"key":"10.1016\/j.ijmm.2020.151416_bib0130","doi-asserted-by":"crossref","first-page":"623","DOI":"10.3349\/ymj.2000.41.5.623","article-title":"Virulent Treponema pallidum 47 kDa antigen regulates the expression of cell adhesion molecules and binding of T-lymphocytes to cultured human dermal microvascular endothelial cells","volume":"41","author":"Lee","year":"2000","journal-title":"Yonsei Med. J."},{"key":"10.1016\/j.ijmm.2020.151416_bib0135","first-page":"539","article-title":"Elevated serum chemerin levels are associated with the presence of coronary artery disease in patients with type 2 diabetes","volume":"58","author":"Lin","year":"2012","journal-title":"Clin. Lab."},{"key":"10.1016\/j.ijmm.2020.151416_bib0140","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.micpath.2017.06.046","article-title":"A preliminary study on the proinflammatory mechanisms of Treponema pallidum outer membrane protein Tp92 in human macrophages and HMEC-1 cells","volume":"110","author":"Luo","year":"2017","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.ijmm.2020.151416_bib0145","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/978-1-4939-2871-2_6","article-title":"Treponema pallidum in gel microdroplets: a method for topological analysis of BamA (TP0326) and localization of rare outer membrane proteins","volume":"1329","author":"Luthra","year":"2015","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0150","doi-asserted-by":"crossref","first-page":"G1","DOI":"10.1152\/ajpgi.90730.2008","article-title":"Epithelial cells in fetal intestine produce chemerin to recruit macrophages","volume":"297","author":"Maheshwari","year":"2009","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0155","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1006\/mpat.1998.0206","article-title":"Omp85 proteins of Neisseria gonorrhoeae and Neisseria meningitidis are similar to Haemophilus influenzae D-15-Ag and Pasteurella multocida Oma87","volume":"25","author":"Manning","year":"1998","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.ijmm.2020.151416_bib0160","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.tcm.2008.11.004","article-title":"Monocyte-endothelial cell interactions in the development of atherosclerosis","volume":"18","author":"Mestas","year":"2008","journal-title":"Trends Cardiovasc. Med."},{"key":"10.1016\/j.ijmm.2020.151416_bib0165","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0378-1135(99)00190-X","article-title":"Overexpression and immunogenicity of the Oma87 outer membrane protein of Pasteurella multocida","volume":"72","author":"Mitchison","year":"2000","journal-title":"Vet. Microbiol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0170","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1359\/jbmr.091106","article-title":"Role of chemerin\/CMKLR1 signaling in adipogenesis and osteoblastogenesis of bone marrow stem cells","volume":"25","author":"Muruganandan","year":"2010","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.ijmm.2020.151416_bib0175","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1161\/HYPERTENSIONAHA.115.05616","article-title":"Chemerin regulates crosstalk between adipocytes and vascular cells through Nox","volume":"66","author":"Neves","year":"2015","journal-title":"Hypertension"},{"key":"10.1016\/j.ijmm.2020.151416_bib0180","doi-asserted-by":"crossref","first-page":"46945","DOI":"10.1038\/srep46945","article-title":"Corrigendum: treponema pallidum (syphilis) antigen TpF1 induces angiogenesis through the activation of the IL-8 pathway","volume":"8","author":"Pozzobon","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ijmm.2020.151416_bib0185","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.4049\/jimmunol.1501113","article-title":"Pro- and anti-inflammatory role of ChemR23 signaling in pollutant-induced inflammatory lung responses","volume":"196","author":"Provoost","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0190","first-page":"1","article-title":"The Treponema pallidum outer membrane","volume":"415","author":"Radolf","year":"2018","journal-title":"Curr. Top. Microbiol. Immunol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0195","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/nrmicro.2016.141","article-title":"Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen","volume":"14","author":"Radolf","year":"2016","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0200","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/jmi.12025","article-title":"RhoA, RhoB and RhoC have different roles in cancer cell migration","volume":"251","author":"Ridley","year":"2013","journal-title":"J. Microsc."},{"key":"10.1016\/j.ijmm.2020.151416_bib0205","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.aai8629","article-title":"RhoB controls the Rab11-mediated recycling and surface reappearance of LFA-1 in migrating T lymphocytes","volume":"10","author":"Samuelsson","year":"2017","journal-title":"Sci. Signal."},{"key":"10.1016\/j.ijmm.2020.151416_bib0210","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.imbio.2007.11.003","article-title":"Immune responses induced by spirochetal outer membrane lipoproteins and glycolipids","volume":"213","author":"Schr\u00f6der","year":"2008","journal-title":"Immunobiology."},{"key":"10.1016\/j.ijmm.2020.151416_bib0215","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S1369-5274(00)00158-2","article-title":"Chlamydia outer membrane protein discovery using genomics","volume":"4","author":"Stephens","year":"2001","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0220","doi-asserted-by":"crossref","first-page":"110","DOI":"10.5604\/01.3001.0010.3795","article-title":"The role of chemerin in human disease","volume":"71","author":"Stojek","year":"2017","journal-title":"Postepy. Hig. Med. Dosw (Online)"},{"key":"10.1016\/j.ijmm.2020.151416_bib0225","doi-asserted-by":"crossref","first-page":"844","DOI":"10.5604\/17322693.1214137","article-title":"Role of omentin and chemerin in metabolic syndrome and tumor diseases","volume":"70","author":"Szyd\u0142o","year":"2016","journal-title":"Postepy. Hig. Med. Dosw (Online)"},{"key":"10.1016\/j.ijmm.2020.151416_bib0230","doi-asserted-by":"crossref","first-page":"2587","DOI":"10.1099\/mic.0.042689-0","article-title":"Assembly of outer membrane proterns in bacteria and mitochondria","volume":"156","author":"Tommassen","year":"2010","journal-title":"Microbiology"},{"key":"10.1016\/j.ijmm.2020.151416_bib0235","doi-asserted-by":"crossref","first-page":"3668","DOI":"10.1128\/JCM.41.8.3668-3674.2003","article-title":"Serodiagnosis of syphilis: antibodies to recombinant Tp0453, Tp92, and Gpd proteins are sensitive and specific indicators of infection by Treponema pallidum","volume":"41","author":"Van Voorhis","year":"2003","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0240","doi-asserted-by":"crossref","first-page":"28599","DOI":"10.1074\/jbc.M109.047282","article-title":"Regulation of immature dendritic cell migration by RhoA guanine nucleotid e exchange factor Arhgef","volume":"284","author":"Wang","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijmm.2020.151416_bib0245","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1161\/ATVBAHA.113.301476","article-title":"Chemerin connects fat to arterial contraction","volume":"33","author":"Watts","year":"2013","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0250","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1111\/j.1574-6976.1998.tb00373.x","article-title":"The genome of Treponema pallidum: new light on the agent of syphilis","volume":"22","author":"Weinstock","year":"1998","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.ijmm.2020.151416_bib0255","first-page":"3096","article-title":"Effects of chemerin\/CMKLR1 in obesity-induced hypertension and potential mechanism","volume":"9","author":"Weng","year":"2017","journal-title":"Am. J. Transl. Res."},{"key":"10.1016\/j.ijmm.2020.151416_bib0260","series-title":"Chlamydia trachomatis, neisseria gonorrhoeae, syphilis and trichomonas vaginalis. Methods and results used by WHO to generate 2005 estimates","article-title":"Prevalence and incidence of selected sexually transmitted infections","author":"World Health Organization","year":"2011"},{"key":"10.1016\/j.ijmm.2020.151416_bib0265","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s11684-017-0577-9","article-title":"Role of chemerin\/CMKLR1 in the maintenance of early pregnancy","volume":"12","author":"Yang","year":"2018","journal-title":"Front. Med."},{"key":"10.1016\/j.ijmm.2020.151416_bib0270","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1084\/jem.20081736","article-title":"Chemerin reveals its chimeric nature","volume":"205","author":"Yoshimura","year":"2008","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ijmm.2020.151416_bib0275","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.yexcr.2010.10.023","article-title":"Chemokine-like receptor 1 (CMKLR1) and chemokine (C-C motif) receptor-like 2 (CCRL2); two multifunctional receptors with unusual properties","volume":"317","author":"Yoshimura","year":"2011","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.ijmm.2020.151416_bib0280","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1084\/jem.20080300","article-title":"Mast cell-expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis","volume":"205","author":"Zabel","year":"2008","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ijmm.2020.151416_bib0285","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1042\/CS20080196","article-title":"Role of TNF-alpha in vascular dysfunction","volume":"116","author":"Zhang","year":"2009","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.ijmm.2020.151416_bib0290","article-title":"Recombinant treponema pallidum protein Tp0965 activates endothelial cells and increases the permeability of endothelial cell monolayer","volume":"9","author":"Zhang","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ijmm.2020.151416_bib0295","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.intimp.2015.02.028","article-title":"Tp17 member protein of treponema pallidum activates endothelial cell in vitro","volume":"25","author":"Zhang","year":"2015","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.ijmm.2020.151416_bib0300","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.4161\/hv.7.10.16541","article-title":"Enhanced immune response and protective efficacy of a Treponema pallidum Tp92 DNA vaccine vectored by chitosan nanoparticles and adjuvanted with IL-2","volume":"7","author":"Zhao","year":"2011","journal-title":"Hum. Vaccin."}],"container-title":["International Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1438422120300266?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1438422120300266?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T16:58:45Z","timestamp":1761411525000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1438422120300266"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":60,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,4]]}},"alternative-id":["S1438422120300266"],"URL":"https:\/\/doi.org\/10.1016\/j.ijmm.2020.151416","relation":{},"ISSN":["1438-4221"],"issn-type":[{"value":"1438-4221","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Treponema pallidum outer membrane protein Tp92 activates endothelial cells via the chemerin\/CMKLR1 pathway","name":"articletitle","label":"Article Title"},{"value":"International Journal of Medical Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijmm.2020.151416","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"151416"}}