{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T07:11:58Z","timestamp":1780384318251,"version":"3.54.1"},"reference-count":104,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T00:00:00Z","timestamp":1705881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Medical Microbiology"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.ijmm.2024.151609","type":"journal-article","created":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T03:01:51Z","timestamp":1706065311000},"page":"151609","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Characteristics of two zoonotic swine influenza A(H1N1) viruses isolated in Germany from diseased patients"],"prefix":"10.1016","volume":"314","author":[{"given":"Alla","family":"Heider","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Wedde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viola","family":"Weinheimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"D\u00f6llinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masyar","family":"Monazahian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"D\u00fcrrwald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thorsten","family":"Wolff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brunhilde","family":"Schweiger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijmm.2024.151609_bib1","doi-asserted-by":"crossref","DOI":"10.2807\/ese.14.07.19120-en","article-title":"Human case of swine influenza A (H1N1), Aragon, Spain, November 2008","volume":"14","author":"Adiego Sancho","year":"2009","journal-title":"Eur. Surveill."},{"key":"10.1016\/j.ijmm.2024.151609_bib2","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a038737","article-title":"Swine influenza a viruses and the tangled relationship with humans","volume":"11","author":"Anderson","year":"2021","journal-title":"Cold Spring Harb. Perspect. Med"},{"key":"10.1016\/j.ijmm.2024.151609_bib3","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/irv.12386","article-title":"Susceptibility of swine to H5 and H7 low pathogenic avian influenza viruses","volume":"10","author":"Balzli","year":"2016","journal-title":"Influenza Other Respir. Virus"},{"key":"10.1016\/j.ijmm.2024.151609_bib4","doi-asserted-by":"crossref","first-page":"6883","DOI":"10.1073\/pnas.111165798","article-title":"Pattern of mutation in the genome of influenza A virus on adaptation to increased virulence in the mouse lung: identification of functional themes","volume":"98","author":"Brown","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ijmm.2024.151609_bib5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0378-1135(00)00164-4","article-title":"The epidemiology and evolution of influenza viruses in pigs","volume":"74","author":"Brown","year":"2000","journal-title":"Vet. Microbiol"},{"key":"10.1016\/j.ijmm.2024.151609_bib6","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1136\/vr.136.13.328","article-title":"Disease outbreaks in pigs in Great Britain due to an influenza A virus of H1N2 subtype","volume":"136","author":"Brown","year":"1995","journal-title":"Vet. Rec."},{"issue":"Pt 12","key":"10.1016\/j.ijmm.2024.151609_bib7","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1099\/0022-1317-79-12-2947","article-title":"Multiple genetic reassortment of avian and human influenza A viruses in European pigs, resulting in the emergence of an H1N2 virus of novel genotype","volume":"79","author":"Brown","year":"1998","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib8","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1051\/vetres\/2010046","article-title":"Experimental infection with H1N1 European swine influenza virus protects pigs from an infection with the 2009 pandemic H1N1 human influenza virus","volume":"41","author":"Busquets","year":"2010","journal-title":"Vet. Res"},{"key":"10.1016\/j.ijmm.2024.151609_bib9","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1006\/viro.1997.8514","article-title":"Continued evolution of H1N1 and H3N2 influenza viruses in pigs in Italy","volume":"232","author":"Campitelli","year":"1997","journal-title":"Virology"},{"key":"10.1016\/j.ijmm.2024.151609_bib10","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1111\/irv.12221","article-title":"Modified vaccinia virus Ankara expressing the hemagglutinin of pandemic (H1N1) 2009 virus induces cross-protective immunity against Eurasian 'avian-like' H1N1 swine viruses in mice","volume":"8","author":"Castrucci","year":"2014","journal-title":"Influenza Other Respir. Virus"},{"key":"10.1016\/j.ijmm.2024.151609_bib11","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1006\/viro.1993.1155","article-title":"Genetic reassortment between avian and human influenza A viruses in Italian pigs","volume":"193","author":"Castrucci","year":"1993","journal-title":"Virology"},{"key":"10.1016\/j.ijmm.2024.151609_bib12","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/0092-8674(82)90135-0","article-title":"The antigenic structure of the influenza virus A\/PR\/8\/34 hemagglutinin (H1 subtype)","volume":"31","author":"Caton","year":"1982","journal-title":"Cell"},{"key":"10.1016\/j.ijmm.2024.151609_bib13","unstructured":"CDC, 2011. Limited Human-to-Human Transmission of Novel Influenza A (H3N2) Virus \u2014 Iowa, 60(47)."},{"key":"10.1016\/j.ijmm.2024.151609_bib14","unstructured":"CDC,2012. H3N2v Update: New Cases Reported, Limited Person-to-Person Transmission Detected (Illinois, Maryland, Michigan, Minnesota, Ohio, Pennsylvania, Wisconsin)."},{"key":"10.1016\/j.ijmm.2024.151609_bib15","doi-asserted-by":"crossref","DOI":"10.1186\/1465-9921-6-135","article-title":"Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells","volume":"6","author":"Chan","year":"2005","journal-title":"Respir. Res"},{"key":"10.1016\/j.ijmm.2024.151609_bib16","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1016\/S0140-6736(02)11772-7","article-title":"Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?","volume":"360","author":"Cheung","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.ijmm.2024.151609_bib17","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1006\/viro.1994.1553","article-title":"Infection of children with avian-human reassortant influenza virus from pigs in Europe","volume":"204","author":"Claas","year":"1994","journal-title":"Virology"},{"key":"10.1016\/j.ijmm.2024.151609_bib18","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1371\/journal.ppat.0030141","article-title":"A single mutation in the PB1-F2 of H5N1 (HK\/97) and 1918 influenza A viruses contributes to increased virulence","volume":"3","author":"Conenello","year":"2007","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijmm.2024.151609_bib19","doi-asserted-by":"crossref","first-page":"8735","DOI":"10.1128\/JVI.00422-14","article-title":"PB2 mutations D701N and S714R promote adaptation of an influenza H5N1 virus to a mammalian host","volume":"88","author":"Czudai-Matwich","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib20","doi-asserted-by":"crossref","first-page":"11667","DOI":"10.1128\/JVI.01142-06","article-title":"Double-stranded RNA binding of influenza B virus nonstructural NS1 protein inhibits protein kinase R but is not essential to antagonize production of alpha\/beta interferon","volume":"80","author":"Dauber","year":"2006","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib21","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1750-2659.2010.00164.x","article-title":"Cross-protection between antigenically distinct H1N1 swine influenza viruses from Europe and North America","volume":"5","author":"De Vleeschauwer","year":"2011","journal-title":"Influenza Other Respir. Virus"},{"key":"10.1016\/j.ijmm.2024.151609_bib22","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3201\/eid2601.191144","article-title":"Locally acquired human infection with swine-origin influenza A(H3N2) variant virus, Australia, 2018","volume":"26","author":"Deng","year":"2020","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ijmm.2024.151609_bib23","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.01581","article-title":"Influenza A virus cell entry, replication, virion assembly and movement","volume":"9","author":"Dou","year":"2018","journal-title":"Front Immunol."},{"key":"10.1016\/j.ijmm.2024.151609_bib24","doi-asserted-by":"crossref","first-page":"5485","DOI":"10.1128\/JVI.02565-08","article-title":"Different evolutionary trajectories of European avian-like and classical swine H1N1 influenza A viruses","volume":"83","author":"Dunham","year":"2009","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib25","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.3201\/eid1606.100138","article-title":"Swine influenza A vaccines, pandemic (H1N1) 2009 virus, and cross-reactivity","volume":"16","author":"D\u00fcrrwald","year":"2010","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ijmm.2024.151609_bib26","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES.2020.25.42.2001638","article-title":"Zoonotic infection with swine A\/H1(av)N1 influenza virus in a child, Germany, June 2020.","volume":"25","author":"D\u00fcrrwald","year":"2020","journal-title":"Eur. Surveill."},{"key":"10.1016\/j.ijmm.2024.151609_bib27","doi-asserted-by":"crossref","DOI":"10.2807\/1560-7917.ES2014.19.18.20793","article-title":"Influenza at the animal-human interface: a review of the literature for virological evidence of human infection with swine or avian influenza viruses other than A(H5N1)","volume":"19","author":"Freidl","year":"2014","journal-title":"Eur. Surveill."},{"key":"10.1016\/j.ijmm.2024.151609_bib28","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.coi.2011.07.016","article-title":"The pathogenesis of influenza virus infections: the contributions of virus and host factors","volume":"23","author":"Fukuyama","year":"2011","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.ijmm.2024.151609_bib29","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1126\/science.1093155","article-title":"The structure and receptor binding properties of the 1918 influenza hemagglutinin","volume":"303","author":"Gamblin","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.ijmm.2024.151609_bib30","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1126\/science.1176225","article-title":"Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans","volume":"325","author":"Garten","year":"2009","journal-title":"Science"},{"issue":"Suppl","key":"10.1016\/j.ijmm.2024.151609_bib31","doi-asserted-by":"crossref","first-page":"S356","DOI":"10.1093\/infdis\/136.Supplement_3.S356","article-title":"Swine influenza A at Fort Dix, New Jersey (January-February 1976). I. Case finding and clinical study of cases","volume":"136","author":"Gaydos","year":"1977","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijmm.2024.151609_bib32","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.3201\/eid1312.061323","article-title":"Swine workers and swine influenza virus infections","volume":"13","author":"Gray","year":"2007","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ijmm.2024.151609_bib33","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1007\/s00705-002-0953-9","article-title":"Human infection by a swine influenza A (H1N1) virus in Switzerland","volume":"148","author":"Gregory","year":"2003","journal-title":"Arch. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib34","doi-asserted-by":"crossref","DOI":"10.3390\/v15091959","article-title":"Fitness determinants of Influenza A Viruses","volume":"15","author":"Griffin","year":"2023","journal-title":"Viruses"},{"key":"10.1016\/j.ijmm.2024.151609_bib35","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.meegid.2010.12.001","article-title":"The role of swine as \"mixing vessel\" for interspecies transmission of the influenza A subtype H1N1: a simultaneous Bayesian inference of phylogeny and ancestral hosts","volume":"11","author":"Hass","year":"2011","journal-title":"Infect. Genet Evol."},{"key":"10.1016\/j.ijmm.2024.151609_bib36","doi-asserted-by":"crossref","DOI":"10.1186\/s40813-022-00274-x","article-title":"Are pigs overestimated as a source of zoonotic influenza viruses?","volume":"8","author":"Hennig","year":"2022","journal-title":"Porc. Health Manag"},{"key":"10.1016\/j.ijmm.2024.151609_bib37","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1126\/science.1213362","article-title":"Airborne transmission of influenza A\/H5N1 virus between ferrets","volume":"336","author":"Herfst","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.ijmm.2024.151609_bib38","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0042-6822(78)90217-9","article-title":"The prevalence of influenza viruses in swine and the antigenic and genetic relatedness of influenza viruses from man and swine","volume":"84","author":"Hinshaw","year":"1978","journal-title":"Virology"},{"key":"10.1016\/j.ijmm.2024.151609_bib39","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0008553","article-title":"Predicting the antigenic structure of the pandemic (H1N1) 2009 influenza virus hemagglutinin","volume":"5","author":"Igarashi","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.ijmm.2024.151609_bib40","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1038\/nature10831","article-title":"Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA\/H1N1 virus in ferrets","volume":"486","author":"Imai","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2024.151609_bib41","doi-asserted-by":"crossref","first-page":"7367","DOI":"10.1128\/JVI.72.9.7367-7373.1998","article-title":"Molecular basis for the generation in pigs of influenza A viruses with pandemic potential","volume":"72","author":"Ito","year":"1998","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib42","doi-asserted-by":"crossref","first-page":"4381","DOI":"10.1073\/pnas.0800482105","article-title":"A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity","volume":"105","author":"Jackson","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ijmm.2024.151609_bib43","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1038\/nm1477","article-title":"Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia","volume":"12","author":"de Jong","year":"2006","journal-title":"Nat. Med"},{"key":"10.1016\/j.ijmm.2024.151609_bib44","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0168-1702(00)00154-4","article-title":"Genetic characterization of H3N2 influenza viruses isolated from pigs in North America, 1977-1999: evidence for wholly human and reassortant virus genotypes","volume":"68","author":"Karasin","year":"2000","journal-title":"Virus Res"},{"key":"10.1016\/j.ijmm.2024.151609_bib45","doi-asserted-by":"crossref","DOI":"10.1186\/1743-422X-7-365","article-title":"Characterization of influenza virus sialic acid receptors in minor poultry species","volume":"7","author":"Kimble","year":"2010","journal-title":"Virol. J."},{"key":"10.1016\/j.ijmm.2024.151609_bib46","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1038\/nature05495","article-title":"Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus","volume":"445","author":"Kobasa","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2024.151609_bib47","first-page":"468","article-title":"A practical method for field diagnosis of swine disease","volume":"14","author":"Koen","year":"1918","journal-title":"Am. J. Vet. Med."},{"key":"10.1016\/j.ijmm.2024.151609_bib48","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00430-013-0309-y","article-title":"Prevalence of antibodies to European porcine influenza viruses in humans living in high pig density areas of Germany","volume":"203","author":"Krumbholz","year":"2014","journal-title":"Med. Microbiol. Immunol."},{"key":"10.1016\/j.ijmm.2024.151609_bib49","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1099\/vir.0.068569-0","article-title":"Origin of the European avian-like swine influenza viruses","volume":"95","author":"Krumbholz","year":"2014","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib50","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1002\/jmv.21869","article-title":"Prevalence of antibodies to swine influenza viruses in humans with occupational exposure to pigs, Thuringia, Germany, 2008-2009","volume":"82","author":"Krumbholz","year":"2010","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib51","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.virusres.2007.08.012","article-title":"Evolutionary analyses of European H1N2 swine influenza A virus by placing timestamps on the multiple reassortment events","volume":"131","author":"Lam","year":"2008","journal-title":"Virus Res"},{"key":"10.1016\/j.ijmm.2024.151609_bib52","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1007\/s00705-013-1950-x","article-title":"Circulation of classical swine influenza virus in Europe between the wars?","volume":"159","author":"Lange","year":"2014","journal-title":"Arch. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib53","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.cell.2014.02.040","article-title":"Identification, characterization, and natural selection of mutations driving airborne transmission of A\/H5N1 virus","volume":"157","author":"Linster","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.ijmm.2024.151609_bib54","doi-asserted-by":"crossref","first-page":"12069","DOI":"10.1128\/JVI.01639-10","article-title":"Altered receptor specificity and cell tropism of D222G hemagglutinin mutants isolated from fatal cases of pandemic A(H1N1) 2009 influenza virus","volume":"84","author":"Liu","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib55","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/nature16474","article-title":"Species difference in ANP32A underlies influenza A virus polymerase host restriction","volume":"529","author":"Long","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2024.151609_bib56","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1111\/zph.12948","article-title":"Evidence of influenza A infection and risk of transmission between pigs and farmworkers","volume":"69","author":"Lopez-Moreno","year":"2022","journal-title":"Zoonoses Public Health"},{"key":"10.1016\/j.ijmm.2024.151609_bib57","doi-asserted-by":"crossref","first-page":"8502","DOI":"10.1128\/JVI.74.18.8502-8512.2000","article-title":"Early alterations of the receptor-binding properties of H1, H2, and H3 avian influenza virus hemagglutinins after their introduction into mammals","volume":"74","author":"Matrosovich","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib58","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1743-422X-3-63","article-title":"New low-viscosity overlay medium for viral plaque assays","volume":"3","author":"Matrosovich","year":"2006","journal-title":"Virol. J."},{"key":"10.1016\/j.ijmm.2024.151609_bib59","doi-asserted-by":"crossref","first-page":"12364","DOI":"10.1128\/JVI.01381-14","article-title":"Epitope mapping of the hemagglutinin molecule of A\/(H1N1)pdm09 influenza virus by using monoclonal antibody escape mutants","volume":"88","author":"Matsuzaki","year":"2014","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib60","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1007\/s11262-011-0571-2","article-title":"Comparison of two H1N2 swine influenza A viruses from disease outbreaks in pigs in Sweden during 2009 and 2010","volume":"42","author":"Metreveli","year":"2011","journal-title":"Virus Genes"},{"key":"10.1016\/j.ijmm.2024.151609_bib61","unstructured":"Murphy, B.,\u00a01996. Fields Virology. Orthomyxoviruses. Lippincott-Raven Philadelphia, PA."},{"key":"10.1016\/j.ijmm.2024.151609_bib62","doi-asserted-by":"crossref","first-page":"1084-8","DOI":"10.1086\/512813","article-title":"Cases of swine influenza in humans: a review of the literature","volume":"44","author":"Myers","year":"2007","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.ijmm.2024.151609_bib63","doi-asserted-by":"crossref","DOI":"10.1186\/1746-6148-6-4","article-title":"Comparative distribution of human and avian type sialic acid influenza receptors in the pig","volume":"6","author":"Nelli","year":"2010","journal-title":"BMC Vet. Res"},{"key":"10.1016\/j.ijmm.2024.151609_bib64","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1038\/nature08157","article-title":"Emergence and pandemic potential of swine-origin H1N1 influenza virus","volume":"459","author":"Neumann","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2024.151609_bib65","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2017.01080","article-title":"Identification of Rare PB2-D701N Mutation from a patient with severe influenza: contribution of the PB2-D701N mutation to the pathogenicity of human influenza","volume":"8","author":"Nieto","year":"2017","journal-title":"Front Microbiol"},{"key":"10.1016\/j.ijmm.2024.151609_bib66","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.3201\/eid1207.060268","article-title":"Triple reassortant H3N2 influenza A viruses, Canada, 2005","volume":"12","author":"Olsen","year":"2006","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ijmm.2024.151609_bib67","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1128\/JVI.01619-09","article-title":"Pandemic H1N1 2009 influenza A virus induces weak cytokine responses in human macrophages and dendritic cells and is highly sensitive to the antiviral actions of interferons","volume":"84","author":"Osterlund","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib68","doi-asserted-by":"crossref","first-page":"4596","DOI":"10.1128\/JVI.00029-11","article-title":"Impact of amino acid mutations in PB2, PB1-F2, and NS1 on the replication and pathogenicity of pandemic (H1N1) 2009 influenza viruses","volume":"85","author":"Ozawa","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib69","doi-asserted-by":"crossref","first-page":"939","DOI":"10.3201\/eid2703.201863","article-title":"Human Infection with Eurasian avian-like swine influenza A(H1N1) Virus, the Netherlands, September 2019","volume":"27","author":"Parys","year":"2021","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ijmm.2024.151609_bib70","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00132-20","article-title":"Swine ANP32A supports avian influenza virus polymerase","volume":"94","author":"Peacock","year":"2020","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib71","first-page":"75","article-title":"Evidence for the natural transmission of influenza A virus from wild ducts to swine and its potential importance for man","volume":"59","author":"Pensaert","year":"1981","journal-title":"Bull. World Health Organ"},{"key":"10.1016\/j.ijmm.2024.151609_bib72","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1000115","article-title":"H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice","volume":"4","author":"Perrone","year":"2008","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijmm.2024.151609_bib73","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1073\/pnas.96.4.1651","article-title":"Origin and evolution of the 1918 \"Spanish\" influenza virus hemagglutinin gene","volume":"96","author":"Reid","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ijmm.2024.151609_bib74","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1128\/JCM.37.4.937-943.1999","article-title":"Detection of antibody to avian influenza A (H5N1) virus in human serum by using a combination of serologic assays","volume":"37","author":"Rowe","year":"1999","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijmm.2024.151609_bib75","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/BF01719674","article-title":"Source for influenza pandemics","volume":"10","author":"Scholtissek","year":"1994","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.ijmm.2024.151609_bib76","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/0042-6822(83)90194-0","article-title":"Genetic relatedness of hemagglutinins of the H1 subtype of influenza A viruses isolated from swine and birds","volume":"129","author":"Scholtissek","year":"1983","journal-title":"Virology"},{"issue":"25","key":"10.1016\/j.ijmm.2024.151609_bib77","doi-asserted-by":"crossref","first-page":"2616","DOI":"10.1056\/NEJMoa0903812","article-title":"Triple-reassortant swine influenza A (H1) in humans in the United States, 2005-2009","volume":"360","author":"Shinde","year":"2009","journal-title":"N. Engl. J. Med"},{"key":"10.1016\/j.ijmm.2024.151609_bib78","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/440435a","article-title":"Avian flu: influenza virus receptors in the human airway","volume":"440","author":"Shinya","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.ijmm.2024.151609_bib79","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1084\/jem.54.3.373","article-title":"Swine influenza: III. Filtration experiments and etiology","volume":"54","author":"Shope","year":"1931","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ijmm.2024.151609_bib80","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1146\/annurev.biochem.69.1.531","article-title":"Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin","volume":"69","author":"Skehel","year":"2000","journal-title":"Annu Rev. Biochem"},{"key":"10.1016\/j.ijmm.2024.151609_bib81","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1056\/NEJM197603252941308","article-title":"Isolation of swine influenza virus from autopsy lung tissue of man","volume":"294","author":"Smith","year":"1976","journal-title":"N. Engl. J. Med"},{"key":"10.1016\/j.ijmm.2024.151609_bib82","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/S0140-6736(00)78541-2","article-title":"A virus obtained from influenza patients","volume":"222","author":"Smith","year":"1933","journal-title":"Lancet"},{"key":"10.1016\/j.ijmm.2024.151609_bib83","doi-asserted-by":"crossref","DOI":"10.3390\/v12010055","article-title":"Identification, genetic analysis, and pathogenicity of classical swine H1N1 and Human-Swine Reassortant H1N1 Influenza Viruses from Pigs in China","volume":"12","author":"Song","year":"2020","journal-title":"Viruses"},{"key":"10.1016\/j.ijmm.2024.151609_bib84","doi-asserted-by":"crossref","first-page":"226","DOI":"10.2183\/pjab.88.226","article-title":"Molecular basis of the structure and function of H1 hemagglutinin of influenza virus","volume":"88","author":"Sriwilaijaroen","year":"2012","journal-title":"Proc. Jpn. Acad. Ser. B Phys. Biol. Sci."},{"key":"10.1016\/j.ijmm.2024.151609_bib85","doi-asserted-by":"crossref","first-page":"17204","DOI":"10.1073\/pnas.1921186117","article-title":"Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection","volume":"117","author":"Sun","year":"2020","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ijmm.2024.151609_bib86","article-title":"Glycosylation site alteration in the evolution of influenza A (H1N1) viruses","volume":"6","author":"Sun","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ijmm.2024.151609_bib87","doi-asserted-by":"crossref","DOI":"10.1128\/mSphere.01043-20","article-title":"Next-generation sequencing analysis of the within-host genetic diversity of influenza A(H1N1)pdm09 viruses in the upper and lower respiratory tracts of patients with severe influenza","volume":"6","author":"Takayama","year":"2021","journal-title":"mSphere"},{"key":"10.1016\/j.ijmm.2024.151609_bib88","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1111\/j.1750-2659.2010.00175.x","article-title":"Transmission of influenza A viruses between pigs and people, Iowa, 2002-2004","volume":"4","author":"Terebuh","year":"2010","journal-title":"Influenza Other Respir. Virus"},{"key":"10.1016\/j.ijmm.2024.151609_bib89","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1164\/ajrccm\/152.4_Pt_2.S25","article-title":"Interspecies transmission of influenza viruses","volume":"152","author":"Webster","year":"1995","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1016\/j.ijmm.2024.151609_bib90","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0057059","article-title":"Predominance of HA-222D\/G polymorphism in influenza A(H1N1)pdm09 viruses associated with fatal and severe outcomes recently circulating in Germany","volume":"8","author":"Wedde","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ijmm.2024.151609_bib91","unstructured":"WHO, 2011. Report prepared for the WHO annual consultation on the composition of influenza vaccine for the Northern Hemisphere 14th - 17th February 2011. WHO Collaborating Centre for Reference and Research on Influenza National Institute for Medical Research, London."},{"key":"10.1016\/j.ijmm.2024.151609_bib92","first-page":"142","article-title":"Antigenic and genetic characteristics of zoonotic influenza viruses and development of candidate vaccine viruses for pandemic preparedness","volume":"93","author":"WHO","year":"2018","journal-title":"Wkly. Epidemiol. Rec."},{"key":"10.1016\/j.ijmm.2024.151609_bib93","doi-asserted-by":"crossref","first-page":"Rrn1152","DOI":"10.1371\/currents.RRN1152","article-title":"Structure and receptor binding properties of a pandemic H1N1 virus hemagglutinin","volume":"2","author":"Yang","year":"2010","journal-title":"PLoS Curr."},{"key":"10.1016\/j.ijmm.2024.151609_bib94","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1099\/vir.0.82378-0","article-title":"Prevalence of PB1-F2 of influenza A viruses","volume":"88","author":"Zell","year":"2007","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib95","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1099\/vir.0.83338-0","article-title":"Novel reassortant of swine influenza H1N2 virus in Germany","volume":"89","author":"Zell","year":"2008","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib96","doi-asserted-by":"crossref","DOI":"10.3390\/v12070762","article-title":"Cocirculation of Swine H1N1 Influenza A Virus Lineages in Germany","volume":"12","author":"Zell","year":"2020","journal-title":"Viruses"},{"key":"10.1016\/j.ijmm.2024.151609_bib97","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s00705-019-04457-w","article-title":"Displacement of the Gent\/1999 human-like swine H1N2 influenza A virus lineage by novel H1N2 reassortants in Germany","volume":"165","author":"Zell","year":"2020","journal-title":"Arch. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib98","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-71275-5","article-title":"Novel reassortant swine H3N2 influenza A viruses in Germany","volume":"10","author":"Zell","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ijmm.2024.151609_bib99","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2301926120","article-title":"The genomic landscape of swine influenza A viruses in Southeast Asia","volume":"120","author":"Zeller","year":"2023","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.ijmm.2024.151609_bib100","doi-asserted-by":"crossref","first-page":"12439","DOI":"10.1128\/JVI.01134-07","article-title":"Highly pathogenic avian influenza H5N1 viruses elicit an attenuated type I interferon response in polarized human bronchial epithelial cells","volume":"81","author":"Zeng","year":"2007","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib101","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1008330","article-title":"A unique feature of swine ANP32A provides susceptibility to avian influenza virus infection in pigs","volume":"16","author":"Zhang","year":"2020","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijmm.2024.151609_bib102","doi-asserted-by":"crossref","first-page":"8851","DOI":"10.1128\/JVI.73.10.8851-8856.1999","article-title":"Genetic reassortment of avian, swine, and human influenza A viruses in American pigs","volume":"73","author":"Zhou","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.ijmm.2024.151609_bib103","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1097\/PCC.0b013e318166fbb5","article-title":"Effects of oxygen concentration and exposure time on cultured human airway epithelial cells","volume":"9","author":"Zhu","year":"2008","journal-title":"Pedia Crit. Care Med"},{"key":"10.1016\/j.ijmm.2024.151609_bib104","doi-asserted-by":"crossref","first-page":"10708","DOI":"10.1128\/JVI.00610-10","article-title":"Virulence determinants of avian H5N1 influenza A virus in mammalian and avian hosts: role of the C-terminal ESEV motif in the viral NS1 protein","volume":"84","author":"Zielecki","year":"2010","journal-title":"J. Virol."}],"container-title":["International Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1438422124000134?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1438422124000134?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T12:18:53Z","timestamp":1718367533000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1438422124000134"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":104,"alternative-id":["S1438422124000134"],"URL":"https:\/\/doi.org\/10.1016\/j.ijmm.2024.151609","relation":{},"ISSN":["1438-4221"],"issn-type":[{"value":"1438-4221","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characteristics of two zoonotic swine influenza A(H1N1) viruses isolated in Germany from diseased patients","name":"articletitle","label":"Article Title"},{"value":"International Journal of Medical Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijmm.2024.151609","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"151609"}}