{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T11:20:37Z","timestamp":1770376837892,"version":"3.49.0"},"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["222574\/Z\/21\/Z"],"award-info":[{"award-number":["222574\/Z\/21\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Medical Microbiology"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.ijmm.2025.151665","type":"journal-article","created":{"date-parts":[[2025,7,16]],"date-time":"2025-07-16T07:38:32Z","timestamp":1752651512000},"page":"151665","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Drug resistance of Mycobacterium tuberculosis in West Java, Indonesia"],"prefix":"10.1016","volume":"320","author":[{"given":"Ariel","family":"Pradipta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David Virya","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ihsan","family":"Fauzan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adhityo","family":"Wicaksono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basti","family":"Andriyoko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rifky Waluyajati","family":"Rachman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gusti Ayu Prani","family":"Pradani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azzania","family":"Fibriani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anuraj H.","family":"Shankar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.ijmm.2025.151665_bib1","first-page":"1128","article-title":"Thin-layer-agar-based direct phenotypic drug susceptibility testing on sputum in Eswatini rapidly detects Mycobacterium tuberculosis growth and rifampicin resistance otherwise missed by WHO-endorsed diagnostic tests","volume":"65","author":"Ardizzoni","year":"2021","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijmm.2025.151665_bib2","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1093\/bioinformatics\/btr174","article-title":"BamTools: a C++ API and toolkit for analyzing and managing BAM files","volume":"27","author":"Barnett","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ijmm.2025.151665_bib3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1186\/s12859-015-0603-3","article-title":"PhyTB: phylogenetic tree visualisation and sample positioning for M. tuberculosis","volume":"16","author":"Benavente","year":"2015","journal-title":"BMC Bioinforma."},{"key":"10.1016\/j.ijmm.2025.151665_bib4","doi-asserted-by":"crossref","first-page":"e00815","DOI":"10.1128\/jcm.00815-24","article-title":"Nanopore-based targeted sequencing test for direct tuberculosis identification, genotyping, and detection of drug resistance mutations: a side-by-side comparison of targeted next-generation sequencing technologies","volume":"62","author":"Cabibbe","year":"2024","journal-title":"J. Clin. Microbiol"},{"key":"10.1016\/j.ijmm.2025.151665_bib5","doi-asserted-by":"crossref","DOI":"10.1093\/gigascience\/giab008","article-title":"Twelve years of SAMtools and BCFtools","volume":"10","author":"Danecek","year":"2021","journal-title":"GigaScience"},{"key":"10.1016\/j.ijmm.2025.151665_bib6","doi-asserted-by":"crossref","DOI":"10.1093\/bioinformatics\/btad311","article-title":"NanoPack2: population-scale evaluation of long-read sequencing data","volume":"39","author":"De Coster","year":"2023","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ijmm.2025.151665_bib7","unstructured":"Global Programme on Tuberculosis and Lung Health (GTB) - WHO, 2023. Use of targeted next-generation sequencing to detect drug-resistant tuberculosis: rapid communication, July 2023. \u3008https:\/\/www.who.int\/publications\/i\/item\/9789240076372\u3009. Last accessed: May 2, 2025."},{"key":"10.1016\/j.ijmm.2025.151665_bib8","unstructured":"Global Programme on Tuberculosis and Lung Health (GTB) - WHO, 2024. WHO consolidated guidelines on tuberculosis: module 3: diagnosis: rapid diagnostics for tuberculosis detection, 3rd ed. \u3008https:\/\/www.who.int\/publications\/i\/item\/9789240089488\u3009. Last accessed: May 2, 2025."},{"key":"10.1016\/j.ijmm.2025.151665_bib9","unstructured":"Indonesian Ministry of Health. 2021. Petunjuk Teknis dan Pemantapan Mutu: Pemeriksaan Biakan, Identifikasi, dan Uji Kepekaan Mycobacterium Tuberculosis Complex terhadap Obat anti Tuberkulosis Pada Media Padat dan Media Cair (in Indonesian). Indonesian Ministry of Health, Jakarta."},{"key":"10.1016\/j.ijmm.2025.151665_bib10","unstructured":"Indonesian Ministry of Health. 2024. Petunjuk Teknis: Penatalaksanaan Tuberkulosis Resistan Obat di Indonesia (in Indonesian). Indonesian Ministry of Health, Jakarta."},{"key":"10.1016\/j.ijmm.2025.151665_bib11","article-title":"Evaluation of diagnostic methods and rifampicin resistance in pulmonary tuberculosis: a hospital-based study","volume":"16","author":"Joshi","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.ijmm.2025.151665_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.tube.2021.102051","article-title":"Targeted next generation sequencing directly from sputum for comprehensive genetic information on drug resistant Mycobacterium tuberculosis","volume":"127","author":"Kambli","year":"2021","journal-title":"Tuberculosis"},{"key":"10.1016\/j.ijmm.2025.151665_bib13","article-title":"Management of drug-resistant tuberculosis in Indonesia: a four-year cascade of care analysis","volume":"22","author":"Lestari","year":"2024","journal-title":"Lancet Reg. Health Southeast Asia"},{"key":"10.1016\/j.ijmm.2025.151665_bib14","first-page":"15","article-title":"Methods for evaluating the accuracy of diagnostic tests","volume":"3","author":"Lim","year":"2021","journal-title":"Cardiovasc Prev. Pharm."},{"key":"10.1016\/j.ijmm.2025.151665_bib15","article-title":"Characteristics and treatment outcomes of patients with MDR and XDR tuberculosis in a TB referral hospital in Beijing: a 13-year experience","volume":"6","author":"Liu","year":"2011","journal-title":"PloS One"},{"key":"10.1016\/j.ijmm.2025.151665_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijmmb.2023.100399","article-title":"Molecular analysis of rpoB gene mutation in MTB detected isolates in a tertiary care centre (AGMC) of North-East, India","volume":"45","author":"Majumdar","year":"2023","journal-title":"Ind. J. Med Microbiol"},{"key":"10.1016\/j.ijmm.2025.151665_bib17","doi-asserted-by":"crossref","first-page":"2277","DOI":"10.3390\/microorganisms11092277","article-title":"Tackling drug-resistant tuberculosis: new challenges from the old pathogen Mycobacterium tuberculosis","volume":"11","author":"Mancuso","year":"2023","journal-title":"Microorganisms"},{"key":"10.1016\/j.ijmm.2025.151665_bib18","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1056\/NEJMra2308181","article-title":"HIV-associated tuberculosis","volume":"391","author":"Meintjes","year":"2024","journal-title":"N. Eng. J. Med"},{"key":"10.1016\/j.ijmm.2025.151665_bib19","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1080\/23744235.2021.1992005","article-title":"Evaluation of the GeneXpert MTB\/RIF assay performance in sputum samples with various characteristics from presumed pulmonary tuberculosis patients in Shiselweni region, Eswatini","volume":"54","author":"Mulengwa","year":"2022","journal-title":"Infect. Dis."},{"key":"10.1016\/j.ijmm.2025.151665_bib20","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2023.1206056","article-title":"Direct detection of drug-resistant Mycobacterium tuberculosis using targeted next generation sequencing","volume":"11","author":"Murphy","year":"2023","journal-title":"Front Public Health"},{"key":"10.1016\/j.ijmm.2025.151665_bib21","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3390\/pathogens13010027","article-title":"Rapid diagnosis of drug-resistant tuberculosis\u2013opportunities and challenges","volume":"13","author":"Naidoo","year":"2023","journal-title":"Pathogens"},{"key":"10.1016\/j.ijmm.2025.151665_bib22","article-title":"Evaluation of diagnostic performance of line probe assay on smear-negative samples of pulmonary tuberculosis","volume":"16","author":"Nandwani","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.ijmm.2025.151665_bib23","unstructured":"NTEP, 2023. CBNAAT Assay Limitations. \u3008https:\/\/ntep.in\/node\/1444\/CP-cbnaat-assay-limitations\u3009 (Last accessed: May 5, 2025)."},{"key":"10.1016\/j.ijmm.2025.151665_bib24","doi-asserted-by":"crossref","first-page":"3601","DOI":"10.1093\/bioinformatics\/bty387","article-title":"Indexed variation graphs for efficient and accurate resistome profiling","volume":"34","author":"Rowe","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ijmm.2025.151665_bib25","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1128\/JCM.03005-13","article-title":"Comparison of Xpert MTB\/RIF with line probe assay for detection of rifampin-monoresistant Mycobacterium tuberculosis","volume":"52","author":"Rufai","year":"2014","journal-title":"J. Clin. Microbiol"},{"key":"10.1016\/j.ijmm.2025.151665_bib26","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1007\/s12070-018-1364-x","article-title":"CBNAAT: a boon for early diagnosis of tuberculosis-head and neck","volume":"70","author":"Sachdeva","year":"2018","journal-title":"Indian J. Otolaryngol. Head. Neck Surg."},{"key":"10.1016\/j.ijmm.2025.151665_bib27","first-page":"99","article-title":"Performance of Xpert\u00ae MTB\/RIF in detecting Multidrug-Resistance Tuberculosis in West Java, Indonesia","volume":"52","author":"Sahiratmadja","year":"2020","journal-title":"Maj. Kedokt. Bdg"},{"key":"10.1016\/j.ijmm.2025.151665_bib28","series-title":"Diagnostic Testing Accuracy: Sensitivity, Specificity, Predictive Values and Likelihood Ratios","author":"Shreffler","year":"2023"},{"key":"10.1016\/j.ijmm.2025.151665_bib29","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.02236-24","article-title":"Discordance in genotypic and phenotypic drug susceptibility results: time to reconsider critical concentration of rifampicin","volume":"13","author":"Shrivas","year":"2025","journal-title":"Microbiol Spectr."},{"key":"10.1016\/j.ijmm.2025.151665_bib30","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0182988","article-title":"Diagnostic utility of a line probe assay for multidrug resistant-TB in smear-negative pulmonary tuberculosis","volume":"12","author":"Singh","year":"2017","journal-title":"PloS One"},{"key":"10.1016\/j.ijmm.2025.151665_bib31","doi-asserted-by":"crossref","DOI":"10.52225\/narra.v3i3.407","article-title":"Profile and risk factors of pre-XDR-TB and XDR-TB patients in a national reference hospital for Sumatra region of Indonesia","volume":"3","author":"Sinulingga","year":"2023","journal-title":"Narra J."},{"key":"10.1016\/j.ijmm.2025.151665_bib32","doi-asserted-by":"crossref","DOI":"10.1080\/22221751.2024.2392656","article-title":"Targeted next-generation sequencing of Mycobacterium tuberculosis from patient samples: lessons learned from high drug-resistant burden clinical settings in Bangladesh","volume":"13","author":"Uddin","year":"2024","journal-title":"Emerg. Microbes Infect."},{"key":"10.1016\/j.ijmm.2025.151665_bib33","unstructured":"WHO. (2022). Line probe assays for detection of drug-resistant tuberculosis: interpretation and reporting manual for laboratory staff and clinicians. World Health Organization. \u3008https:\/\/apps.who.int\/iris\/bitstream\/handle\/10665\/354240\/9789240046665-eng.pdf\u3009 (last accessed Feb 5, 2025)."},{"key":"10.1016\/j.ijmm.2025.151665_bib34","unstructured":"WHO. 2024a. Tuberculosis profile. \u3008https:\/\/worldhealthorg.shinyapps.io\/tb_profiles\u3009 (last accessed Feb 5, 2025)."},{"key":"10.1016\/j.ijmm.2025.151665_bib35","unstructured":"WHO. 2024b. Indonesia. \u3008https:\/\/data.who.int\/countries\/360\u3009 (last accessed Feb 5, 2025)."},{"key":"10.1016\/j.ijmm.2025.151665_bib36","unstructured":"WHO. 2025. World health statistics 2025 - Monitoring health for the SDGs, Sustainable Development Goals. \u3008https:\/\/www.who.int\/publications\/i\/item\/9789240110496\u3009 (last accessed June 25, 2025)."},{"issue":"11","key":"10.1016\/j.ijmm.2025.151665_bib37","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1002\/phar.1482","article-title":"Bedaquiline: a novel antitubercular agent for the treatment of multidrug-resistant tuberculosis","volume":"34","author":"Worley","year":"2014","journal-title":"Pharm. J. Hum. Pharm. Drug Ther."},{"key":"10.1016\/j.ijmm.2025.151665_bib38","article-title":"Targeted next-generation sequencing - a promising approach in the diagnosis of Mycobacterium tuberculosis and drug resistance","author":"Wu","year":"2024","journal-title":"Infection"},{"key":"10.1016\/j.ijmm.2025.151665_bib39","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.ijid.2022.04.061","article-title":"Prediction of Mycobacterium tuberculosis drug resistance by nucleotide MALDI-TOF-MS","volume":"121","author":"Wu","year":"2022","journal-title":"Int J. Infect. Dis."},{"key":"10.1016\/j.ijmm.2025.151665_bib40","article-title":"Diagnostic value of tNGS vs Xpert MTB\/RIF in childhood TB","volume":"10","author":"Zheng","year":"2024","journal-title":"Heliyon"}],"container-title":["International Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1438422125000219?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1438422125000219?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T19:59:12Z","timestamp":1770321552000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1438422125000219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":40,"alternative-id":["S1438422125000219"],"URL":"https:\/\/doi.org\/10.1016\/j.ijmm.2025.151665","relation":{},"ISSN":["1438-4221"],"issn-type":[{"value":"1438-4221","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Drug resistance of Mycobacterium tuberculosis in West Java, Indonesia","name":"articletitle","label":"Article Title"},{"value":"International Journal of Medical Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijmm.2025.151665","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}],"article-number":"151665"}}