{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:19:46Z","timestamp":1786990786958,"version":"build-2736575974"},"reference-count":35,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Indian Journal of Medical Microbiology"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.ijmmb.2022.07.013","type":"journal-article","created":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T08:56:59Z","timestamp":1660294619000},"page":"480-484","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Interpretation, pitfalls of biomarkers in diagnosis of invasive fungal diseases"],"prefix":"10.1016","volume":"40","author":[{"given":"Cornelia","family":"Lass-Florl","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Alastruey-Izquierdo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9582-9556","authenticated-orcid":false,"given":"Renu","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arunloke","family":"Chakroborti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijmmb.2022.07.013_bib1","first-page":"57","article-title":"Global and multi-national prevalence of fungal diseases\u2014estimate precision","volume":"3","author":"Bongomin","year":"2017","journal-title":"J\u00a0Fungi"},{"issue":"12","key":"10.1016\/j.ijmmb.2022.07.013_bib2","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1016\/j.jiph.2019.05.007","article-title":"Epidemiology and burden of invasive fungal infections in the countries of the Arab League","volume":"13","author":"Kmeid","year":"2020","journal-title":"J\u00a0Infect Public Health"},{"issue":"1","key":"10.1016\/j.ijmmb.2022.07.013_bib3","doi-asserted-by":"crossref","first-page":"18","DOI":"10.3109\/13693786.2011.602989","article-title":"Opportunistic fungal infections in the Asia-Pacific region","volume":"50","author":"Slavin","year":"2012","journal-title":"Med Mycol"},{"issue":"2","key":"10.1016\/j.ijmmb.2022.07.013_bib4","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s00134-014-3603-2","article-title":"Incidence, characteristics and outcome of ICU-acquired candidemia in India","volume":"41","author":"Chakrabarti","year":"2014","journal-title":"Intensive Care Med"},{"key":"10.1016\/j.ijmmb.2022.07.013_bib5","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jcrc.2019.02.005","article-title":"Epidemiology and clinical outcomes of invasive mould infections in Indian intensive care units (FISF study)","volume":"51","author":"Chakrabarti","year":"2019","journal-title":"J\u00a0Crit Care"},{"key":"10.1016\/j.ijmmb.2022.07.013_bib6","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s40121-020-00315-4","article-title":"Pulmonary aspergillosis: an evolving challenge for diagnosis and treatment","volume":"9","author":"Russo","year":"2020","journal-title":"Infect Dis Ther"},{"key":"10.1016\/j.ijmmb.2022.07.013_bib7","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.3389\/fmicb.2019.02903","article-title":"A\u00a0new age in molecular diagnostics for invasive fungal disease: are we ready?","volume":"10","author":"Kidd","year":"2020","journal-title":"Front Microbial"},{"issue":"1","key":"10.1016\/j.ijmmb.2022.07.013_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.37201\/req\/2260.2019","article-title":"Biomarkers of fungal infection: expert opinion on the current situations","volume":"33","author":"Bouza","year":"2020","journal-title":"Rev Espa\u00f1ola Quimioter"},{"issue":"6","key":"10.1016\/j.ijmmb.2022.07.013_bib9","doi-asserted-by":"crossref","first-page":"S381","DOI":"10.1086\/430920","article-title":"Design issues in studies evaluating diagnostic tests for aspergillosis","volume":"41","author":"Marr","year":"2005","journal-title":"Clin Infect Dis"},{"issue":"5","key":"10.1016\/j.ijmmb.2022.07.013_bib10","first-page":"38","article-title":"A\u00a0review of a diagnostic tool: galactomannan","volume":"2","author":"Avcu","year":"2018","journal-title":"J\u00a0Immunol Sci"},{"issue":"6","key":"10.1016\/j.ijmmb.2022.07.013_bib11","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1093\/cid\/ciz1008","article-title":"Revision and update of the consensus definitions of invasive fungal disease from the European organization for Research and treatment of cancer and the Mycoses study group education and Research Consortium","volume":"71","author":"Donnelly","year":"2020","journal-title":"Clin Infect Dis"},{"issue":"8","key":"10.1016\/j.ijmmb.2022.07.013_bib12","doi-asserted-by":"crossref","first-page":"e327","DOI":"10.1016\/S1470-2045(14)70017-8","article-title":"Fourth European Conference on Infections in Leukaemia (ECIL-4): guidelines for diagnosis, prevention, and treatment of invasive fungal diseases in paediatric patients with cancer or allogeneic haemopoietic stem-cell transplantation","volume":"15","author":"Groll","year":"2014","journal-title":"Lancet Oncol"},{"issue":"6","key":"10.1016\/j.ijmmb.2022.07.013_bib13","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.00053-20","article-title":"Evaluation of the performance of the IMMY sona Aspergillus galactomannan lateral flow assay when testing serum to aid in diagnosis of invasive aspergillosis","volume":"58","author":"White","year":"2020","journal-title":"J\u00a0Clin Microbiol"},{"issue":"1","key":"10.1016\/j.ijmmb.2022.07.013_bib14","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/myc.12704","article-title":"Clinical evaluation of the newly formatted lateral-flow device for invasive pulmonary aspergillosis","volume":"61","author":"Hoenigl","year":"2017","journal-title":"Mycoses"},{"issue":"7","key":"10.1016\/j.ijmmb.2022.07.013_bib15","doi-asserted-by":"crossref","DOI":"10.1128\/JCM.00136-19","article-title":"Evaluation of a novel Aspergillus antigen enzyme-linked immunosorbent assay","volume":"57","author":"Dichtl","year":"2019","journal-title":"J\u00a0Clin Microbiol"},{"issue":"4","key":"10.1016\/j.ijmmb.2022.07.013_bib16","first-page":"253","article-title":"Comparison of \u03b2-D-glucan and galactomannan in serum for detection of invasive aspergillosis: retrospective analysis with focus on early diagnosis","volume":"6","author":"Dichtl","year":"2020","journal-title":"J\u00a0Fungi"},{"key":"10.1016\/j.ijmmb.2022.07.013_bib17","doi-asserted-by":"crossref","first-page":"181","DOI":"10.5858\/arpa.2014-0230-RS","article-title":"Application of the 1,3-\u03b2-d-Glucan (Fungitell) assay in the diagnosis of invasive fungal infections","volume":"140","author":"Tran","year":"2016","journal-title":"Arch Pathol Lab Med"},{"issue":"6","key":"10.1016\/j.ijmmb.2022.07.013_bib18","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1093\/cid\/ciq206","article-title":"\u03b2-D-Glucan assay for the diagnosis of invasive fungal infections: a meta-analysis","volume":"52","author":"Karageorgopoulos","year":"2011","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.ijmmb.2022.07.013_bib19","doi-asserted-by":"crossref","first-page":"S102","DOI":"10.1093\/cid\/ciaa1943","article-title":"Assessment of the role of 1,3-\u03b2-d-Glucan testing for the diagnosis of invasive fungal infections in adults","volume":"72","author":"Lamoth","year":"2021","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijmmb.2022.07.013_bib20","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1093\/jpids\/pix054","article-title":"Role of molecular biomarkers in the diagnosis of invasive fungal diseases in children","volume":"6","author":"Huppler","year":"2017","journal-title":"J\u00a0Pediatric Infect Dis Soc"},{"issue":"3","key":"10.1016\/j.ijmmb.2022.07.013_bib21","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1586\/14737159.8.3.315","article-title":"Contribution of serum biomarkers to the diagnosis of invasive candidiasis","volume":"8","author":"La\u00edn","year":"2008","journal-title":"Expert Rev Mol Diagn"},{"issue":"6","key":"10.1016\/j.ijmmb.2022.07.013_bib22","doi-asserted-by":"crossref","first-page":"R222","DOI":"10.1186\/cc9365","article-title":"The use of mannan antigen and anti-mannan antibodies in the diagnosis of invasive candidiasis: recommendations from the Third European Conference on Infections in Leukemia","volume":"14","author":"Mikulska","year":"2010","journal-title":"Crit Care"},{"issue":"7","key":"10.1016\/j.ijmmb.2022.07.013_bib23","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1093\/cid\/ciaa1243","article-title":"Cryptococcal antigen in serum and cerebrospinal fluid for detecting cryptococcal meningitis in adults living with human immunodeficiency virus: systematic review and meta-analysis of diagnostic test accuracy studies","volume":"72","author":"Temfack","year":"2020","journal-title":"Clin Infect Dis"},{"issue":"1","key":"10.1016\/j.ijmmb.2022.07.013_bib24","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3201\/eid2001.130906","article-title":"Multisite validation of cryptococcal antigen lateral flow assay and quantification by laser thermal contrast","volume":"20","author":"Boulware","year":"2014","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.ijmmb.2022.07.013_bib25","doi-asserted-by":"crossref","first-page":"409","DOI":"10.3389\/fmicb.2018.00409","article-title":"Cryptococcal antigen screening in asymptomatic HIV-infected antiretroviral na\u00efve patients in Cameroon and evaluation of the new semi-quantitative biosynex CryptoPS test","volume":"9","author":"Temfack","year":"2018","journal-title":"Front Microbiol"},{"issue":"3","key":"10.1016\/j.ijmmb.2022.07.013_bib26","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1517\/17530059.2012.681300","article-title":"CrAg lateral flow assay for cryptococcosis","volume":"6","author":"Kozel","year":"2012","journal-title":"Expert Opin Med Diagn"},{"issue":"8","key":"10.1016\/j.ijmmb.2022.07.013_bib27","doi-asserted-by":"crossref","first-page":"2472","DOI":"10.1128\/JCM.00751-17","article-title":"Low Cryptococcus antigen titers as determined by lateral flow assay should Be interpreted cautiously in patients without prior diagnosis of cryptococcal infection","volume":"55","author":"Dubbels","year":"2017","journal-title":"J\u00a0Clin Microbiol"},{"issue":"8","key":"10.1016\/j.ijmmb.2022.07.013_bib28","first-page":"636","article-title":"Rapid genomic diagnosis of fungal infections in the age of next-generation sequencing","volume":"7","author":"Tsang","year":"2021","journal-title":"J\u00a0Fungi"},{"issue":"2","key":"10.1016\/j.ijmmb.2022.07.013_bib29","first-page":"132","article-title":"Evaluation of three commercial PCR assays for the detection of azole-resistant Aspergillus fumigatus from respiratory samples of immunocompromised patients","volume":"7","author":"Scharmann","year":"2021","journal-title":"J\u00a0Fungi"},{"key":"10.1016\/j.ijmmb.2022.07.013_bib30","first-page":"18","article-title":"Blood Aspergillus PCR: the good, the bad, and the ugly","volume":"6","author":"Egger","year":"2020","journal-title":"J\u00a0Fungi"},{"issue":"1","key":"10.1016\/j.ijmmb.2022.07.013_bib31","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.diagmicrobio.2016.10.005","article-title":"Evaluation of a new commercial real-time PCR assay for diagnosis of Pneumocystis jirovecii pneumonia and identification of dihydropteroate synthase (DHPS) mutations","volume":"87","author":"Montesinos","year":"2017","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"3","key":"10.1016\/j.ijmmb.2022.07.013_bib32","first-page":"178","article-title":"T2Candida for the diagnosis and management of invasive Candida infections","volume":"7","author":"Monday","year":"2021","journal-title":"J\u00a0Fungi (Basel)"},{"key":"10.1016\/j.ijmmb.2022.07.013_bib33","doi-asserted-by":"crossref","DOI":"10.1093\/jac\/dky050","article-title":"T2 magnetic resonance for the diagnosis of bloodstream infections: charting a path forward","volume":"73","author":"Clancy","year":"2018","journal-title":"J\u00a0Antimicrob Chemother"},{"issue":"6","key":"10.1016\/j.ijmmb.2022.07.013_bib34","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1093\/cid\/ciu959","article-title":"T2 magnetic resonance assay for the rapid diagnosis of candidemia in whole blood: a clinical trial","volume":"60","author":"Mylonakis","year":"2015","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijmmb.2022.07.013_bib35","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2021.709315","article-title":"Genetic susceptibility to fungal infections and links to human ancestry","volume":"12","author":"Naik","year":"2021","journal-title":"Front Genet"}],"container-title":["Indian Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0255085722001360?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0255085722001360?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T19:19:27Z","timestamp":1759346367000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0255085722001360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S0255085722001360"],"URL":"https:\/\/doi.org\/10.1016\/j.ijmmb.2022.07.013","relation":{},"ISSN":["0255-0857"],"issn-type":[{"value":"0255-0857","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Interpretation, pitfalls of biomarkers in diagnosis of invasive fungal diseases","name":"articletitle","label":"Article Title"},{"value":"Indian Journal of Medical Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijmmb.2022.07.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}