{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T17:59:16Z","timestamp":1772647156315,"version":"3.50.1"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100009530","name":"Assam University, Silchar","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Indian Journal of Medical Microbiology"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.ijmmb.2024.100535","type":"journal-article","created":{"date-parts":[[2024,2,14]],"date-time":"2024-02-14T21:11:45Z","timestamp":1707945105000},"page":"100535","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Molecular characterization of enteropathogenic Escherichia coli isolated from patients with gastroenteritis in a tertiary referral hospital of northeast India"],"prefix":"10.1016","volume":"47","author":[{"given":"Sayani","family":"Roy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barnamoy","family":"Bhattacharjee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0926-6636","authenticated-orcid":false,"given":"Pranab Behari","family":"Mazumder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohana","family":"Bhattacharjee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debadatta","family":"Dhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amitabha","family":"Bhattacharjee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijmmb.2024.100535_bib1","series-title":"Essentials of medical microbiology","author":"Sastry","year":"2018"},{"key":"10.1016\/j.ijmmb.2024.100535_bib2","series-title":"Koneman's color atlas and textbook of diagnostic microbiology","author":"Procop","year":"2020"},{"issue":"3","key":"10.1016\/j.ijmmb.2024.100535_bib3","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1172\/JCI116717","article-title":"Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection","volume":"92","author":"Donnenberg","year":"1993","journal-title":"J Clin Investig"},{"issue":"10","key":"10.1016\/j.ijmmb.2024.100535_bib4","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.3390\/antibiotics11101333","article-title":"Prevalence of multidrug-resistant diarrheagenic Escherichia coli in asia: a systematic review and meta-analysis","volume":"11","author":"Salleh","year":"2022","journal-title":"Antibiotics"},{"issue":"12","key":"10.1016\/j.ijmmb.2024.100535_bib5","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1586\/14787210.2014.976612","article-title":"Tackling antibiotic resistance in India","volume":"12","author":"Wattal","year":"2014","journal-title":"Expert Rev Anti Infect Ther"},{"key":"10.1016\/j.ijmmb.2024.100535_bib6","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1590\/S1517-83822005000400011","article-title":"Comparison of DNA-extraction methods and selective enrichment broths on the detection of Salmonella Typhimurium in swine feces by polymerase chain reaction (PCR)","volume":"36","author":"Freschi","year":"2005","journal-title":"Braz J Microbiol"},{"issue":"6","key":"10.1016\/j.ijmmb.2024.100535_bib7","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1128\/JCM.40.6.2009-2015.2002","article-title":"Antibiotic resistance, virulence gene, and molecular profiles of Shiga toxin-producing Escherichia coli isolates from diverse sources in Calcutta, India","volume":"40","author":"Khan","year":"2002","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijmmb.2024.100535_bib8","doi-asserted-by":"crossref","first-page":"386","DOI":"10.4103\/ijph.ijph_347_22","article-title":"Occurrence of atypical enteropathogenic Escherichia coli with multidrug-resistant trait in street food of Northeast India","volume":"66","author":"Roy","year":"2022","journal-title":"Indian J Publ Health"},{"issue":"3","key":"10.1016\/j.ijmmb.2024.100535_bib9","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1093\/jac\/dkp498","article-title":"Development of a set of multiplex PCR assays for the detection of genes encoding important \u03b2-lactamases in Enterobacteriaceae","volume":"65","author":"Dallenne","year":"2010","journal-title":"J Antimicrob Chemother"},{"issue":"4","key":"10.1016\/j.ijmmb.2024.100535_bib10","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1128\/AAC.01195-06","article-title":"Prevalence of plasmid-mediated quinolone resistance determinants QnrA, QnrB, and QnrS among clinical isolates of Enterobacter cloacae in a Taiwanese hospital","volume":"51","author":"Wu","year":"2007","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijmmb.2024.100535_bib11","article-title":"Occurrence of blaOXA-48 type carbapenemase in Escherichia coli with coexisting resistance determinants: a report from India","volume":"26","author":"Das","year":"2022","journal-title":"Gen Rep"},{"issue":"4","key":"10.1016\/j.ijmmb.2024.100535_bib12","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1128\/AAC.39.4.824","article-title":"Plasmid-mediated dissemination of the metallo-beta-lactamase gene blaIMP among clinically isolated strains of Serratia marcescens","volume":"39","author":"Ito","year":"1995","journal-title":"Antimicrob Agents Chemother"},{"issue":"12","key":"10.1016\/j.ijmmb.2024.100535_bib13","doi-asserted-by":"crossref","first-page":"5046","DOI":"10.1128\/AAC.00774-09","article-title":"Characterization of a new metallo-\u03b2-lactamase gene, bla NDM-1, and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India","volume":"53","author":"Yong","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"issue":"9","key":"10.1016\/j.ijmmb.2024.100535_bib14","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1128\/AAC.40.9.2080","article-title":"Characterization of IMI-1 beta-lactamase, a class A carbapenem-hydrolyzing enzyme from Enterobacter cloacae","volume":"40","author":"Rasmussen","year":"1996","journal-title":"Antimicrob Agents Chemother"},{"issue":"24","key":"10.1016\/j.ijmmb.2024.100535_bib15","doi-asserted-by":"crossref","first-page":"6823","DOI":"10.1093\/nar\/19.24.6823","article-title":"Distribution of repetitive DNA sequences in eubacteria and application to fingerprinting of bacterial genomes","volume":"19","author":"Versalovic","year":"1991","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.ijmmb.2024.100535_bib16","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.bjm.2016.10.015","article-title":"Diarrheagenic Escherichia coli","author":"Gomes","year":"2016","journal-title":"Braz J Microbiol"},{"issue":"3","key":"10.1016\/j.ijmmb.2024.100535_bib17","first-page":"400","article-title":"Molecular typing of enteropathogenic Escherichia coli from diarrheagenic stool samples","volume":"6","author":"Dhanashree","year":"2012","journal-title":"J Clin Diagn Res"},{"issue":"11","key":"10.1016\/j.ijmmb.2024.100535_bib18","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1086\/379666","article-title":"Atypical enteropathogenic Escherichia coli strains: phenotypic and genetic profiling reveals a strong association between enteroaggregative E. coli heat-stable enterotoxin and diarrhea","volume":"188","author":"Dulguer","year":"2003","journal-title":"J Infect Dis"},{"issue":"5","key":"10.1016\/j.ijmmb.2024.100535_bib19","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1086\/318821","article-title":"Phenotypic and Genotypic characteristics of Escherichia coli strains of non\u2013enteropathogenic E. coli (EPEC) serogroups that carry eae and lack the EPEC adherence factor and shiga toxin DNA probe sequences","volume":"183","author":"Vieira","year":"2001","journal-title":"J Infect Dis"},{"issue":"4","key":"10.1016\/j.ijmmb.2024.100535_bib20","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0890-8508(03)00046-X","article-title":"Subtyping intimin genes from enteropathogenic Escherichia coli associated with outbreaks and sporadic cases in the United Kingdom and Eire","volume":"17","author":"Jenkins","year":"2003","journal-title":"Mol Cell Probes"},{"issue":"5","key":"10.1016\/j.ijmmb.2024.100535_bib21","doi-asserted-by":"crossref","first-page":"508","DOI":"10.3201\/eid0805.010385","article-title":"Typical and atypical enteropathogenic Escherichia coli","volume":"8","author":"Trabulsi","year":"2002","journal-title":"Emerg Infect Dis"},{"issue":"11","key":"10.1016\/j.ijmmb.2024.100535_bib22","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1099\/jmm.0.45719-0","article-title":"Association of atypical enteropathogenic Escherichia coli (EPEC) with prolonged diarrhoea","volume":"53","author":"Afset","year":"2004","journal-title":"J Med Microbiol"},{"issue":"1","key":"10.1016\/j.ijmmb.2024.100535_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s41043-018-0147-z","article-title":"A study of virulence and antimicrobial resistance pattern in diarrhoeagenic Escherichia coli isolated from diarrhoeal stool specimens from children and adults in a tertiary hospital, Puducherry, India","volume":"37","author":"Natarajan","year":"2018","journal-title":"J Health Popul Nutr"},{"issue":"4","key":"10.1016\/j.ijmmb.2024.100535_bib24","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1128\/microbiolspec.EHEC-0024-2013","article-title":"Shiga toxin (Stx) classification, structure, and function","volume":"2","author":"Melton-Celsa","year":"2014","journal-title":"Microbiol Spectr"},{"issue":"1","key":"10.1016\/j.ijmmb.2024.100535_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0732-8893(01)00325-X","article-title":"Evaluation of the VTEC-Screen \u201cSeiken\u201d test for detection of different types of Shiga toxin (verotoxin)-producing Escherichia coli (STEC) in human stool samples","volume":"42","author":"Beutin","year":"2002","journal-title":"Diagn Microbiol Infect Dis"},{"issue":"1","key":"10.1016\/j.ijmmb.2024.100535_bib26","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1128\/JCM.40.1.271-274.2002","article-title":"Direct detection and characterization of shiga toxigenic Escherichia coli by multiplex PCR for stx1, stx2, eae, ehxA, and saa","volume":"40","author":"Paton","year":"2002","journal-title":"J Clin Microbiol"},{"issue":"1","key":"10.1016\/j.ijmmb.2024.100535_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2180-10-25","article-title":"Genetic elements associated with antimicrobial resistance in enteropathogenic Escherichia coli (EPEC) from Brazil","volume":"10","author":"Scaletsky","year":"2010","journal-title":"BMC Microbiol"},{"issue":"5839","key":"10.1016\/j.ijmmb.2024.100535_bib28","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1126\/science.1142284","article-title":"Adaptive mutations in bacteria: high rate and small effects","volume":"317","author":"Perfeito","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.ijmmb.2024.100535_bib29","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.ijmmb.2022.10.013","article-title":"Editorial: MDR pathogens in India are difficult to treat","volume":"41","author":"Wattal","year":"2023","journal-title":"Indian J Med Microbiol"},{"key":"10.1016\/j.ijmmb.2024.100535_bib30","article-title":"Molecular characterization and prevalence of virulence factor genes of Shiga toxin-producing Escherichia coli (STEC) isolated from diarrheic children","volume":"25","author":"Moeinirad","year":"2021","journal-title":"Gene Rep"},{"issue":"3","key":"10.1016\/j.ijmmb.2024.100535_bib31","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1128\/AAC.02909-15","article-title":"Plasmid-mediated quinolone resistance in different diarrheagenic Escherichia coli pathotypes responsible for complicated, noncomplicated, and traveler's diarrhea cases","volume":"60","author":"Herrera-Leon","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"10.1016\/j.ijmmb.2024.100535_bib32","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.1365-2036.2009.04028.x","article-title":"Systematic review: the epidemiology and clinical features of travellers' diarrhoea","volume":"30","author":"Dupont","year":"2009","journal-title":"Aliment Pharmacol Ther"},{"issue":"1","key":"10.1016\/j.ijmmb.2024.100535_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12941-017-0225-x","article-title":"Prevalence of multi drug resistant enteropathogenic and enteroinvasive Escherichia coli isolated from children with and without diarrhea in Northeast Indian population","volume":"16","author":"Chellapandi","year":"2017","journal-title":"Ann Clin Microbiol Antimicrob"},{"issue":"2","key":"10.1016\/j.ijmmb.2024.100535_bib34","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1016\/j.rvsc.2011.12.011","article-title":"Characterization of shiga toxin producing (STEC) and enteropathogenic Escherichia coli (EPEC) in raw yak (Poephagus grunniens) milk and milk products","volume":"93","author":"Bandyopadhyay","year":"2012","journal-title":"Res Vet Sci"}],"container-title":["Indian Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0255085724000100?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0255085724000100?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T19:21:42Z","timestamp":1759346502000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0255085724000100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":34,"alternative-id":["S0255085724000100"],"URL":"https:\/\/doi.org\/10.1016\/j.ijmmb.2024.100535","relation":{},"ISSN":["0255-0857"],"issn-type":[{"value":"0255-0857","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular characterization of enteropathogenic Escherichia coli isolated from patients with gastroenteritis in a tertiary referral hospital of northeast India","name":"articletitle","label":"Article Title"},{"value":"Indian Journal of Medical Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijmmb.2024.100535","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"100535"}}