{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T00:46:26Z","timestamp":1781484386204,"version":"3.54.1"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Indian Journal of Medical Microbiology"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.ijmmb.2026.101073","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:29:44Z","timestamp":1770078584000},"page":"101073","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Comparative evaluation of practical in-vitro methods for testing synergy between ceftazidime-avibactam and aztreonam against metallo-\u03b2-lactamase and serine carbapenemase-producing Enterobacterales species"],"prefix":"10.1016","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2504-0941","authenticated-orcid":false,"given":"Neha Sunil","family":"Bawankar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0545-7373","authenticated-orcid":false,"given":"Samrin Ejaz Hussain","family":"Sayed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swati M.","family":"Bhise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5367-1137","authenticated-orcid":false,"given":"Rajni","family":"Gaind","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijmmb.2026.101073_bib1","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.3390\/healthcare11131946","article-title":"Antimicrobial resistance: a growing serious threat for global public health","volume":"11","author":"Salam","year":"2023","journal-title":"Healthcare"},{"key":"10.1016\/j.ijmmb.2026.101073_bib2","doi-asserted-by":"crossref","first-page":"74","DOI":"10.3389\/fmed.2019.00074","article-title":"Treatment of infections due to MDR gram-negative bacteria","volume":"6","author":"Bassetti","year":"2019","journal-title":"Front Med"},{"key":"10.1016\/j.ijmmb.2026.101073_bib3","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.jgar.2022.01.025","article-title":"A practical laboratory method to determine ceftazidime-avibactam-aztreonam synergy in patients with New Delhi metallo-beta-lactamase (NDM)-producing Enterobacterales infection","volume":"29","author":"Rawson","year":"2022","journal-title":"J Glob Antimicrob Resist"},{"key":"10.1016\/j.ijmmb.2026.101073_bib4","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.3390\/antibiotics12071134","article-title":"Efficacy of novel combinations of antibiotics against multidrug-resistant-new Delhi Metallo-\u03b2-Lactamase-Producing strains of Enterobacterales","volume":"12","author":"Khalid","year":"2023","journal-title":"Antibiot (Basel)"},{"key":"10.1016\/j.ijmmb.2026.101073_bib5","doi-asserted-by":"crossref","DOI":"10.1128\/aac.00751-22","article-title":"Ceftazidime-Avibactam plus aztreonam for the treatment of infections by VIM-Type-Producing gram-negative bacteria","volume":"66","author":"Sempere","year":"2022","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijmmb.2026.101073_bib6","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.jgar.2023.08.010","article-title":"In vitro effectiveness of ceftazidime-avibactam in combination with aztreonam on carbapenemase-producing Enterobacterales","volume":"35","author":"Romina","year":"2023","journal-title":"J Glob Antimicrob Resist"},{"key":"10.1016\/j.ijmmb.2026.101073_bib7","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1038\/s41429-022-00537-3","article-title":"In-vitro susceptibility testing methods for the combination of ceftazidime-avibactam with aztreonam in metallobeta-lactamase producing organisms: role of combination drugs in antibiotic resistance era","volume":"75","author":"Sreenivasan","year":"2022","journal-title":"J Antibiot"},{"key":"10.1016\/j.ijmmb.2026.101073_bib8","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1093\/cid\/ciaa586","article-title":"Efficacy of ceftazidime-avibactam plus aztreonam in patients with blood stream infections caused by MBL-producing Enterobacterales","volume":"72","author":"Falcone","year":"2021","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijmmb.2026.101073_bib9","first-page":"134","article-title":"Detection of Metallo beta-lactamase (MBL) producing Pseudomonas aeruginosa in a tertiary care Hospital, ghanpur, Medchal, India","volume":"17","author":"Radhika","year":"2022","journal-title":"Maedica (Bucur)"},{"key":"10.1016\/j.ijmmb.2026.101073_bib10","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.3201\/eid2710.211265","article-title":"New Delhi Metallo-\u03b2-Lactamase-Producing Enterobacterales bacteria, Switzerland, 2019-2020","volume":"27","author":"Findlay","year":"2021","journal-title":"Emerg Infect Dis"},{"issue":"10","key":"10.1016\/j.ijmmb.2026.101073_bib11","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1089\/mdr.2024.0059","article-title":"Characterization of the chromosomally Located Metallo-\u03b2-Lactamase Genes bla IMP-45 and bla VIM-2 in a Carbapenem-Resistant Pseudomonas aeruginosa Clinical Isolate","volume":"30","author":"Ma","year":"2024","journal-title":"Microb Drug Resist"},{"key":"10.1016\/j.ijmmb.2026.101073_bib12","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1186\/s12866-016-0763-y","article-title":"Risk factors for fecal carriage of carbapenemase producing Enterobacteriaceae among intensive care unit patients from a tertiary care center in India","volume":"16","author":"Mittal","year":"2016","journal-title":"BMC Microbiol"},{"issue":"2","key":"10.1016\/j.ijmmb.2026.101073_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0247418","article-title":"Molecular characterization and antibiotic resistance of Acinetobacter baumannii in cerebrospinal fluid and blood","volume":"16","author":"Shi","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.ijmmb.2026.101073_bib14","article-title":"Evaluation of a simple method for testing aztreonam and ceftazidime-avibactam synergy in new Delhi Metallo-\u03b2-Lactamase-Producing Enterobacterales","volume":"19","author":"Khan","year":"2024","journal-title":"PLoS One"},{"key":"10.1016\/j.ijmmb.2026.101073_bib15","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.3390\/antibiotics10081012","article-title":"The revival of aztreonam in combination with avibactam against Metallo-\u03b2-Lactamase-Producing Gram-Negatives: a systematic review of In vitro studies and clinical cases","volume":"10","author":"Mauri","year":"2021","journal-title":"Antibiot (Basel)"},{"key":"10.1016\/j.ijmmb.2026.101073_bib16","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s12941-023-00573-3","article-title":"Ceftazidime-Avibactam plus aztreonam synergistic combination tested against carbapenem-resistant Enterobacterales characterized phenotypically and genotypically: a glimmer of hope","volume":"22","author":"Taha","year":"2023","journal-title":"Ann Clin Microbiol Antimicrob"},{"key":"10.1016\/j.ijmmb.2026.101073_bib17","article-title":"Is the Ceftazidime-avibactam plus aztreonam combination a solution for infections caused by metallo-\u03b2-lactamase producing carbapenem-resistant Enterobacterales? A call for further investigation","volume":"114","author":"Bawankar","year":"2025","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.ijmmb.2026.101073_bib18","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.00779-19","article-title":"Evaluation of the synergy of ceftazidime-avibactam in combination with meropenem, amikacin, aztreonam, colistin, or fosfomycin against well-characterized multidrug-resistant Klebsiella pneumoniae and Pseudomonas aeruginosa","volume":"63","author":"Mikhail","year":"2019","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.ijmmb.2026.101073_bib19","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.ijmmb.2021.12.006","article-title":"Susceptibility testing for aztreonam plus ceftazidime\/avibactam combination: a general guidance for clinical microbiology laboratories in India","volume":"40","author":"Bakthavatchalam","year":"2022","journal-title":"Indian J Med Microbiol"},{"key":"10.1016\/j.ijmmb.2026.101073_bib20","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.01647-22","article-title":"Multicenter evaluation of an MIC-Based Aztreonam and ceftazidime-avibactam broth disk elution Test","volume":"61","author":"Harris","year":"2023","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.ijmmb.2026.101073_bib21","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1080\/23744235.2020.1788224","article-title":"Phenotypic synergy testing of ceftazidime-avibactam with aztreonam in a university hospital having high number of metallobetalactamase producing bacteria","volume":"52","author":"Sahu","year":"2020","journal-title":"Infect Dis (Lond)"}],"container-title":["Indian Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0255085726000319?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0255085726000319?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T17:39:04Z","timestamp":1773682744000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0255085726000319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":21,"alternative-id":["S0255085726000319"],"URL":"https:\/\/doi.org\/10.1016\/j.ijmmb.2026.101073","relation":{},"ISSN":["0255-0857"],"issn-type":[{"value":"0255-0857","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparative evaluation of practical in-vitro methods for testing synergy between ceftazidime-avibactam and aztreonam against metallo-\u03b2-lactamase and serine carbapenemase-producing Enterobacterales species","name":"articletitle","label":"Article Title"},{"value":"Indian Journal of Medical Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijmmb.2026.101073","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101073"}}