{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T08:39:23Z","timestamp":1792399163037,"version":"4.4.0"},"reference-count":10,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Indian Journal of Medical Microbiology"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.ijmmb.2026.101320","type":"journal-article","created":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T15:14:51Z","timestamp":1792077291000},"page":"101320","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["The diagnostic gap in hepatitis C confirmation and the predictive value of the anti-HCV signal-to-cutoff ratio: a real-world study"],"prefix":"10.1016","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4781-3802","authenticated-orcid":false,"given":"Mehmet","family":"Ceylan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8264-4372","authenticated-orcid":false,"given":"Cansel","family":"Da\u011fdelen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4876-8441","authenticated-orcid":false,"given":"Biray","family":"Do\u011fanay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1027-7578","authenticated-orcid":false,"given":"G\u00fcne\u015f","family":"\u015eenol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijmmb.2026.101320_bib1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1146\/annurev-med-050223-111239","article-title":"Global elimination of hepatitis C virus","volume":"76","author":"Fleurence","year":"2025","journal-title":"Annu Rev Med"},{"issue":"2","key":"10.1016\/j.ijmmb.2026.101320_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr6902a1","article-title":"CDC recommendations for hepatitis C screening among adults \u2014 united States, 2020","volume":"69","author":"Schillie","year":"2020","journal-title":"MMWR Recomm Rep (Morb Mortal Wkly Rep)"},{"issue":"3","key":"10.1016\/j.ijmmb.2026.101320_bib3","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1055\/s-0038-1666841","article-title":"The micro-elimination approach to eliminating hepatitis C: strategic and operational considerations","volume":"38","author":"Lazarus","year":"2018","journal-title":"Semin Liver Dis"},{"issue":"7","key":"10.1016\/j.ijmmb.2026.101320_bib4","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0101554","article-title":"The treatment cascade for chronic hepatitis C virus infection in the United States: a systematic review and meta-analysis","volume":"9","author":"Yehia","year":"2014","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.ijmmb.2026.101320_bib5","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1093\/cid\/ciad126","article-title":"Reflex hepatitis C virus viral load testing following an initial positive hepatitis C virus antibody test: a global systematic review and meta-analysis","volume":"77","author":"Tao","year":"2023","journal-title":"Clin Infect Dis"},{"issue":"4","key":"10.1016\/j.ijmmb.2026.101320_bib6","doi-asserted-by":"crossref","first-page":"302","DOI":"10.3904\/kjim.2009.24.4.302","article-title":"Significance of anti-HCV signal-to-cutoff ratio in predicting hepatitis C viremia","volume":"24","author":"Seo","year":"2009","journal-title":"Korean J Intern Med"},{"issue":"8","key":"10.1016\/j.ijmmb.2026.101320_bib7","doi-asserted-by":"crossref","DOI":"10.1590\/1806-9282.20240370","article-title":"The usefulness of anti-HCV signal to cut-off ratio in predicting hepatitis C viremia and the effect of genotype differences on signal to cut-off ratio","volume":"70","author":"Sar\u0131kaya","year":"2024","journal-title":"Rev Assoc Med Bras"},{"issue":"2","key":"10.1016\/j.ijmmb.2026.101320_bib8","doi-asserted-by":"crossref","first-page":"185","DOI":"10.4103\/0973-6247.154259","article-title":"Establishing a sample-to cut-off ratio for lab-diagnosis of hepatitis C virus in Indian context","volume":"9","author":"Tiwari","year":"2015","journal-title":"Asian J Transfus Sci"},{"issue":"Suppl 3","key":"10.1016\/j.ijmmb.2026.101320_bib9","doi-asserted-by":"crossref","first-page":"S357","DOI":"10.1093\/infdis\/jiad191","article-title":"Maximizing reflexive hepatitis C virus (HCV) RNA testing of HCV antibody-reactive samples within United States public health laboratories","volume":"229","author":"Johnson","year":"2024","journal-title":"J Infect Dis"},{"issue":"4","key":"10.1016\/j.ijmmb.2026.101320_bib10","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.ijmmb.2021.07.002","article-title":"Utility of hepatitis C virus core antigen testing for diagnosis and treatment monitoring in HCV infection: a study from India","volume":"39","author":"Kumbhar","year":"2021","journal-title":"Indian J Med Microbiol"}],"container-title":["Indian Journal of Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0255085726002793?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0255085726002793?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T07:43:01Z","timestamp":1792395781000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0255085726002793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":10,"alternative-id":["S0255085726002793"],"URL":"https:\/\/doi.org\/10.1016\/j.ijmmb.2026.101320","relation":{},"ISSN":["0255-0857"],"issn-type":[{"value":"0255-0857","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The diagnostic gap in hepatitis C confirmation and the predictive value of the anti-HCV signal-to-cutoff ratio: a real-world study","name":"articletitle","label":"Article Title"},{"value":"Indian Journal of Medical Microbiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijmmb.2026.101320","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"101320"}}