{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T16:22:01Z","timestamp":1788538921560,"version":"build-2803163510"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2013,7,1]],"date-time":"2013-07-01T00:00:00Z","timestamp":1372636800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,1,5]],"date-time":"2015-01-05T00:00:00Z","timestamp":1420416000000},"content-version":"vor","delay-in-days":553,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>\n                      The goal of this study is to describe the experience with smear microscopy examination for acid-fast bacilli (AFB) of spontaneous sputum from children in a district hospital located in a rural zone of Ethiopia. All sputum reports of children were retrospectively reviewed from July 2007 until June 2012. During the period of study, 875 children less than 15 years old were screened and 48 (5.5%, 95% confidence interval [CI]: 4.1\u20137.3%) were diagnosed with pulmonary tuberculosis sputum smear positive. The mean age of the children with sputum positive for AFB was significantly higher than children with sputum negative for AFB (11.4 versus 10.4) (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      =0.001). Only 1 out of 47 (1.3%) children of 6 years or less had sputum positive for AFB. In 13- and 14-year-old children, 8.7% had sputum positive for AFB (20 of 229) (\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      = 0.03). Spontaneous sputum has a low diagnostic yield in childhood in low-income countries. Alternative methods should be implemented in rural areas to improve diagnosis of pulmonary TB, particularly in children less than 12 years old.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.ijmyco.2013.04.007","type":"journal-article","created":{"date-parts":[[2013,5,17]],"date-time":"2013-05-17T05:45:32Z","timestamp":1368769532000},"page":"171-173","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Evaluation of Ziehl\u2013Neelsen smear for diagnosis of pulmonary tuberculosis in childhood in a rural hospital in Ethiopia"],"prefix":"10.4103","volume":"2","author":[{"given":"Jos\u00e9 Manuel","family":"Ramos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"P\u00e9rez-Butrague\u00f1o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel","family":"Tisiano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tafese","family":"Yohannes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Reyes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"G\u00f3rgolas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R3-9-20260904","doi-asserted-by":"crossref","first-page":"579","DOI":"10.5588\/ijtld.11.0617","article-title":"Microscopy compared to culture for the diagnosis of tuberculosis in induced sputum samples: a systematic review","volume":"16","author":"Hepple","year":"2012","journal-title":"Int. J. Tuberc. Lung Dis"},{"key":"R4-9-20260904","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.prrv.2010.09.008","article-title":"New specimens and laboratory diagnostics for childhood pulmonary TB: progress and prospects","volume":"12","author":"Nicol","year":"2011","journal-title":"Paediatr. Respir. 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Tuberc. Lung Dis"},{"key":"R8-9-20260904","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/S0140-6736(05)17702-2","article-title":"Induced sputum versus gastric lavage for microbiological confirmation of pulmonary tuberculosis in infants and young children. A prospective study","volume":"365","author":"Zar","year":"2005","journal-title":"Lancet"},{"key":"R9-9-20260904","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1086\/516782","article-title":"Prospective study of sputum induction, gastric washing and broncoalveolar lavage for the diagnosis of pulmonary tuberculosis in patients who are unable to expectorate","volume":"44","author":"Brown","year":"2007","journal-title":"Clin. Infect. Dis"}],"container-title":["The International Journal of Mycobacteriology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S2212553113000344?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/api.elsevier.com\/content\/article\/PII:S2212553113000344?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ovid.com\/01929415-201302030-00009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T16:01:59Z","timestamp":1788537719000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01929415-201302030-00009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijmyco.2013.04.007","relation":{},"ISSN":["2212-5531","2212-554X"],"issn-type":[{"value":"2212-5531","type":"print"},{"value":"2212-554X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}