{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T23:14:27Z","timestamp":1790205267305,"version":"4.1.0"},"reference-count":37,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,3,21]],"date-time":"2015-03-21T00:00:00Z","timestamp":1426896000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2015,4]]},"abstract":"\n Aims:<\/jats:title>\n The current study was designed to document medicinal plant species that are traditionally used to treat tuberculosis (TB) by Ghanaian communities.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n The medicinal plants used against TB or its signs and symptoms were selected using library and online published data searches. A guided questionnaire interview was also conducted with a botanist involved in plant collection at the Centre for Scientific Research into Plant Medicine (CSRPM) at Mampong. Data obtained were entered in Excel and summarized into means and frequencies using SPSS 12.0.1 for windows, and expressed as tables and bar graphs.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n A total of 15 medicinal plant species distributed between 13 genera and 13 families were documented. The following medicinal plant species were found to be used against TB in Greater Accra and Eastern parts of Ghana:\n Azadirachta indica<\/jats:italic>\n A. Juss. Stem bark (Meliaceae),\n Hygrophila auriculata<\/jats:italic>\n Heine, whole plant (Acanthaceae),\n Chenopodium ambrosioides<\/jats:italic>\n L. leaves (Amaranthaceae),\n Coix lacryma-jobi<\/jats:italic>\n L. glumes (Poaceae),\n Solanum torvum<\/jats:italic>\n Sw. unripe fruits (Solanaceae),\n Solanum torvum<\/jats:italic>\n Sw. leaves (Solanaceae),\n Bidens pilosa<\/jats:italic>\n L. whole plant (Asteraceae),\n Phyllanthus fraternus<\/jats:italic>\n G.L. Webster leaves (Phyllanthaceae),\n Dissotis rotundifolia<\/jats:italic>\n (Sm.) Triana, leaves (Melastomataceae),\n Cymbopogon giganteus<\/jats:italic>\n Chiov. Leaves (Poaceae),\n Cyperus articulatus<\/jats:italic>\n L. roots (Cyperaceae),\n Allium sativum<\/jats:italic>\n L. bulb (Amaryllidaceae),\n Zingiber officinale<\/jats:italic>\n Roscoe, rhizomes (Zingiberaceae),\n Allium cepa<\/jats:italic>\n L. bulbs (Amaryllidaceae),\n Allium cepa<\/jats:italic>\n L. leaves (Amaryllidaceae),\n Aloe vera var. barbadensis<\/jats:italic>\n aqueous extract from leaves (Xanthorrhoeaceae),\n Aloe vera var. barbadensis<\/jats:italic>\n organic extract from leaves (Xanthorrhoeaceae),\n Cocos nucifera<\/jats:italic>\n Linn, water (Arecaceae) and\n Cocos nucifera<\/jats:italic>\n Linn. Husk (Arecaceae).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n The collected plant species could be a source of a new class of drugs against TB. Bioactivity guided fractionation is recommended to identify lead compounds for antimycobacterial activity. The current paper documents for the first time medicinal plant species used by Ghanaian communities to treat TB. These results are a basis for selection of plants for further pharmacological, toxicological and phytochemical studies in developing new plant-based antimycobacterial drugs.<\/jats:p>\n <\/jats:sec>","DOI":"10.1016\/j.ijmyco.2015.02.003","type":"journal-article","created":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T03:48:58Z","timestamp":1428292138000},"page":"116-123","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":75,"title":["Medicinal plants used to treat TB in Ghana"],"prefix":"10.4103","volume":"4","author":[{"given":"Joseph Mwanzia","family":"Nguta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Regina","family":"Appiah-Opong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander K.","family":"Nyarko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothy","family":"Yeboah-Manu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phyllis G.A.","family":"Addo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-5-20260907","first-page":"1320","article-title":"Mechanisms of drug resistance in Mycobacterium tuberculosis","volume":"13","author":"Zhang","year":"2009","journal-title":"Int. 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