{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T07:31:24Z","timestamp":1777534284520,"version":"3.51.4"},"reference-count":41,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,9,1]],"date-time":"2013-09-01T00:00:00Z","timestamp":1377993600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Nursing Studies"],"published-print":{"date-parts":[[2013,9]]},"DOI":"10.1016\/j.ijnurstu.2012.11.023","type":"journal-article","created":{"date-parts":[[2012,12,14]],"date-time":"2012-12-14T13:30:41Z","timestamp":1355491841000},"page":"1283-1287","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Ethical and legal issues in pain research in cognitively impaired older adults"],"prefix":"10.1016","volume":"50","author":[{"given":"Todd B.","family":"Monroe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keela A.","family":"Herr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorraine C.","family":"Mion","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald L.","family":"Cowan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0005","series-title":"Involving People with Dementia in Research","author":"Alzheimer Europe","year":"2010"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0010","series-title":"Ethics of Dementia Research","author":"Alzheimer Europe","year":"2011"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0015","series-title":"Ethical Issues in Dementia Research","author":"Alzheimer's Association","year":"2007"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0020","series-title":"Alzheimer's Disease Facts and Figures","author":"Alzheimer's Association","year":"2011"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0025","series-title":"Ethical Principles for Pain-related Clinical Research","author":"American Pain Society","year":"2012"},{"issue":"25","key":"10.1016\/j.ijnurstu.2012.11.023_bib0030","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1056\/NEJM198812223192504","article-title":"Assessing patients\u2019 capacities to consent to treatment","volume":"319","author":"Appelbaum","year":"1988","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0035","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1097\/00002093-200304001-00003","article-title":"Surrogate decision-making and related issues","volume":"17","author":"Beck","year":"2003","journal-title":"Alzheimer Disease and Associated Disorders"},{"issue":"3","key":"10.1016\/j.ijnurstu.2012.11.023_bib0040","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/j.1526-4637.2011.01325.x","article-title":"The ethics of pain clinical trials on persons lacking judgment ability: much to improve","volume":"13","author":"Bellieni","year":"2012","journal-title":"Pain Medicine"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0045","series-title":"The Benefits of Varying Bath Water Temperatures","author":"Brann","year":"2012"},{"issue":"4","key":"10.1016\/j.ijnurstu.2012.11.023_bib0050","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1016\/S0885-3924(03)00097-6","article-title":"Assessing decision-making capacity in the setting of palliative care research","volume":"25","author":"Casarett","year":"2003","journal-title":"Journal of Pain and Symptom Management"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0055","first-page":"28003","article-title":"Common rule, Federal policy for the protection of human subjects; Notices and rules","volume":"56","author":"CFR","year":"1991","journal-title":"Federal Register"},{"issue":"1","key":"10.1016\/j.ijnurstu.2012.11.023_bib0060","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1136\/gut.13.1.24","article-title":"The relationship between the ingestion of hot coffee and intraoesophageal temperature","volume":"13","author":"De Jong","year":"1972","journal-title":"Gut"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0065","first-page":"661","article-title":"Dementia research: ethics and policy for the twenty-first century","volume":"35","author":"Dresser","year":"2000","journal-title":"Georgia Law Review"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0070","article-title":"On the need for improved protections of incapacitated and non-benefiting research subjects","author":"Eriksson","year":"2010","journal-title":"Bioethics"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0075","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"Mini-mental state: a practical method for grading the cogntive state of patietns for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"The Journal of Psychiatric Research"},{"issue":"1","key":"10.1016\/j.ijnurstu.2012.11.023_bib0080","first-page":"26","article-title":"Pain management and provider liability: no more excuses","volume":"29","author":"Furrow","year":"2001","journal-title":"The Journal of Law and Ethics"},{"issue":"6","key":"10.1016\/j.ijnurstu.2012.11.023_bib0085","article-title":"Clinical trial injuries: will your client lose his\/her medical practice?","volume":"22","author":"Goldfarb","year":"2005","journal-title":"Law Journal Newsletters"},{"issue":"3","key":"10.1016\/j.ijnurstu.2012.11.023_bib0090","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1111\/j.1526-4637.2009.00566.x","article-title":"Transforming long-term care pain management in North America: the policy\u2013clinical interface","volume":"10","author":"Hadjistavropoulos","year":"2009","journal-title":"Pain Medicine"},{"issue":"3, Supplement","key":"10.1016\/j.ijnurstu.2012.11.023_bib0095","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.jpain.2010.11.011","article-title":"Pain assessment strategies in older patients","volume":"12","author":"Herr","year":"2011","journal-title":"The Journal of Pain"},{"issue":"4","key":"10.1016\/j.ijnurstu.2012.11.023_bib0100","first-page":"46","article-title":"Assessment of pain in older adults with severe cognitive impairment","volume":"12","author":"Herr","year":"2004","journal-title":"Annals of Long Term Care"},{"issue":"3","key":"10.1016\/j.ijnurstu.2012.11.023_bib0105","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0749-0690(05)70080-X","article-title":"Assessment and measurement of pain in older adults","volume":"17","author":"Herr","year":"2001","journal-title":"Clinics in Geriatric Medicine"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0110","series-title":"Patients\u2019 Rights: From Alder Hey to the Nuremberg Code","author":"Hurren","year":"2003"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0115","series-title":"Ethical Guidelines for Pain Research in Humans","author":"International Association for the Study of Pain","year":"2012"},{"issue":"1","key":"10.1016\/j.ijnurstu.2012.11.023_bib0120","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1526-4637.2004.04013.x","article-title":"Of self-determination, care by proxy, and new techniques","volume":"5","author":"Jansen","year":"2004","journal-title":"Pain Medicine"},{"issue":"8","key":"10.1016\/j.ijnurstu.2012.11.023_bib0125","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1001\/archpsyc.64.8.966","article-title":"A new brief instrument for assessing decisional capactiy for clinical research","volume":"64","author":"Jeste","year":"2007","journal-title":"Archives of General Psychiatry"},{"issue":"4","key":"10.1016\/j.ijnurstu.2012.11.023_bib0130","doi-asserted-by":"crossref","first-page":"S14","DOI":"10.1016\/S0885-3924(03)00098-8","article-title":"Conducting research that involves subjects at the end of life who are unable to give consent","volume":"25","author":"Karlawish","year":"2003","journal-title":"Journal of Pain and Symptom Management"},{"issue":"14","key":"10.1016\/j.ijnurstu.2012.11.023_bib0135","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1056\/NEJMsb030172","article-title":"Research involving cognitively impaired adults","volume":"348","author":"Karlawish","year":"2003","journal-title":"New England Journal of Medicine"},{"issue":"2","key":"10.1016\/j.ijnurstu.2012.11.023_bib0140","doi-asserted-by":"crossref","first-page":"103","DOI":"10.3928\/19404921-20090401-08","article-title":"Considerations of informed consent and decision-making competence in older adults with cognitive impairment","volume":"2","author":"Mayo","year":"2009","journal-title":"Research in Gerontological Nursing"},{"issue":"4","key":"10.1016\/j.ijnurstu.2012.11.023_bib0145","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jpainsymman.2010.06.007","article-title":"A retrospective pilot study of African-American and Caucasian nursing home residents with dementia who died from cancer","volume":"40","author":"Monroe","year":"2010","journal-title":"Journal of Pain and Symptom Management"},{"issue":"9","key":"10.1016\/j.ijnurstu.2012.11.023_bib0150","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1111\/j.1365-2648.2011.05929.x","article-title":"Assessing advanced cancer pain in older adults with dementia at the end-of-life","volume":"68","author":"Monroe","year":"2012","journal-title":"Journal of Advanced Nursing"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0155","unstructured":"Monroe, T., Chin, L., Gore, J., Mion, L., Cowan, R., in press. Pain research in people with Alzheimer's disease: potential applications for psychophysical and neurophysiological studies. Journal of Geriatric Psychiatry and Neurology."},{"issue":"4","key":"10.1016\/j.ijnurstu.2012.11.023_bib0160","doi-asserted-by":"crossref","first-page":"m174","DOI":"10.1093\/geronj\/49.4.M174","article-title":"MDS cognitive performance scale","volume":"49","author":"Morris","year":"1994","journal-title":"Journal of Gerontology"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0165","series-title":"Research Involving Persons with Mental Disorders that May Affect Decisionmaking Capacity","author":"National Bioethics Advisory Commission","year":"1998"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0170","series-title":"Dementia: Ethical Issues","author":"Nuffield Council on Bioethics","year":"2009"},{"issue":"9","key":"10.1016\/j.ijnurstu.2012.11.023_bib0175","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1111\/j.1526-4637.2011.01211.x","article-title":"Improving the pharmacologic management of pain in older adults: identifying the research gaps and methods to address them","volume":"12","author":"Reid","year":"2011","journal-title":"Pain Medicine"},{"issue":"3","key":"10.1016\/j.ijnurstu.2012.11.023_bib0180","first-page":"63","article-title":"Thinking the unthinkable","volume":"18","author":"Rich","year":"2004","journal-title":"Journal of Pain and Palliative Care Pharmacotherapy"},{"issue":"20","key":"10.1016\/j.ijnurstu.2012.11.023_bib0185","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1056\/NEJM199711133372006","article-title":"Fifty years later: the significance of the Nuremberg Code","volume":"337","author":"Shuster","year":"1997","journal-title":"New England Journal of Medicine"},{"issue":"3","key":"10.1016\/j.ijnurstu.2012.11.023_bib0190","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1532-5415.2011.03847.x","article-title":"The disappearing subject: exclusion of people with cognitive impairment and dementia from geriatrics research","volume":"60","author":"Taylor","year":"2012","journal-title":"Journal of the American Geriatrics Society"},{"key":"10.1016\/j.ijnurstu.2012.11.023_bib0195","series-title":"The Belmont Report","author":"U.S. Department of Health and Human Services","year":"1979"},{"issue":"8","key":"10.1016\/j.ijnurstu.2012.11.023_bib0200","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1136\/jme.2005.014043","article-title":"Assessing research risks systematically: the net risks test","volume":"33","author":"Wendler","year":"2007","journal-title":"Journal of Medical Ethics"},{"issue":"23","key":"10.1016\/j.ijnurstu.2012.11.023_bib0205","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1001\/jama.284.23.3043","article-title":"World medical association declaration of Helsinki","volume":"284","author":"World Medical Association","year":"2000","journal-title":"Journal of the American Medical Association"}],"container-title":["International Journal of Nursing Studies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020748912004257?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020748912004257?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T13:27:30Z","timestamp":1758115650000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020748912004257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9]]},"references-count":41,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2013,9]]}},"alternative-id":["S0020748912004257"],"URL":"https:\/\/doi.org\/10.1016\/j.ijnurstu.2012.11.023","relation":{},"ISSN":["0020-7489"],"issn-type":[{"value":"0020-7489","type":"print"}],"subject":[],"published":{"date-parts":[[2013,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ethical and legal issues in pain research in cognitively impaired older adults","name":"articletitle","label":"Article Title"},{"value":"International Journal of Nursing Studies","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijnurstu.2012.11.023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}