{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T13:47:56Z","timestamp":1781876876883,"version":"3.54.5"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,3,1]],"date-time":"2016-03-01T00:00:00Z","timestamp":1456790400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Nursing Studies"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1016\/j.ijnurstu.2015.10.012","type":"journal-article","created":{"date-parts":[[2015,11,18]],"date-time":"2015-11-18T21:48:21Z","timestamp":1447883301000},"page":"39-49","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"special_numbering":"C","title":["Direct and indirect costs and resource use in dementia care: A cross-sectional study in patients living at home"],"prefix":"10.1016","volume":"55","author":[{"given":"Marta","family":"Farr\u00e9","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep Maria","family":"Haro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belchin","family":"Kostov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carme","family":"Alvira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ester","family":"Risco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susana","family":"Miguel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ester","family":"Cabrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adelaida","family":"Zabalegui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0245","article-title":"The association between positive\u2013negative reactions of informal caregivers of people with dementia and health outcomes in eight European countries: a cross-sectional study","author":"Alvira","year":"2014","journal-title":"J. Adv. Nurs."},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0135","series-title":"Policy in Practice","author":"Alzheimer Europe","year":"2010"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0020","series-title":"Alzheimer 2010: Evoluci\u00f3n humana, Evoluci\u00f3n del Alzheimer","first-page":"83","article-title":"Situaci\u00f3n de la asistencia a pacientes con enfermedad de Alzheimer grave","author":"Ant\u00f3n Jim\u00e9nez","year":"2010"},{"issue":"5","key":"10.1016\/j.ijnurstu.2015.10.012_bib0160","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"J. Chron. Dis."},{"issue":"2","key":"10.1016\/j.ijnurstu.2015.10.012_bib0025","doi-asserted-by":"crossref","first-page":"601","DOI":"10.3233\/JAD-2010-1258","article-title":"Prospective one-year cost-of-illness study in a cohort of patients with dementia of Alzheimer's disease type in Spain: the ECO study","volume":"19","author":"Coduras","year":"2010","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0285","series-title":"Enfermedad de Alzheimer y otras Demencias","first-page":"101","article-title":"La familia y los cuidados informales en la demencia. Diferencias entre c\u00f3nyuges e hijos cuidadores","author":"Conde-Sala","year":"2010"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0235","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/852368","article-title":"Comparison of informal care time and costs in different age-related N dementias: a review","author":"Costa","year":"2013","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0070","article-title":"Relationship between global severity of patients with Alzheimer's disease and costs of care in Spain; results from the co-dependence study in Spain","author":"Darb\u00e0","year":"2014","journal-title":"Eur. J. Health Econ."},{"issue":"11","key":"10.1016\/j.ijnurstu.2015.10.012_bib0260","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/j.jamda.2014.06.015","article-title":"Associated factors with antipsychotic use in long-term institutional care in eight European countries: results from the RightTimePlaceCare study","volume":"15","author":"De Mauleon","year":"2014","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0095","series-title":"Methods for the Economic Evaluation of Health Care Programmes","author":"Drummond","year":"2005"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0215","series-title":"Ellviva","year":"2012"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0190","series-title":"Eurostat Database","year":"2013"},{"issue":"5","key":"10.1016\/j.ijnurstu.2015.10.012_bib0110","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1002\/gps.1984","article-title":"Alzheimer's disease in real life \u2013 the dementia career's survey","volume":"23","author":"Georges","year":"2008","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"9","key":"10.1016\/j.ijnurstu.2015.10.012_bib0280","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1001\/archinternmed.2009.43","article-title":"Syncope and its consequences in patients with dementia receiving cholinesterase inhibitors: a population-based Cohort study","volume":"169","author":"Gill","year":"2009","journal-title":"Arch. Intern. Med."},{"issue":"8","key":"10.1016\/j.ijnurstu.2015.10.012_bib0085","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1007\/s12603-010-0311-7","article-title":"Differences in resource use and costs of dementia care between European countries: baseline data from the ICTUS study","volume":"14","author":"Gustavsson","year":"2010","journal-title":"J. Nutr. Health Aging"},{"issue":"3","key":"10.1016\/j.ijnurstu.2015.10.012_bib0195","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.jalz.2010.09.001","article-title":"Predictors of costs of care in Alzheimer's disease: a multinational sample of 1222 patients","volume":"7","author":"Gustavsson","year":"2011","journal-title":"Alzheimer's Dement."},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0265","first-page":"14","article-title":"Donepezil for the treatment of agitation in Alzheimer's disease","volume":"357","author":"Howard","year":"2008","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.ijnurstu.2015.10.012_bib0010","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1056\/NEJMc1305541","article-title":"Monetary cost of dementia in the United States","volume":"369","author":"Hurd","year":"2013","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.ijnurstu.2015.10.012_bib0060","doi-asserted-by":"crossref","first-page":"391","DOI":"10.2165\/00019053-200927050-00004","article-title":"The cost of dementia in Europe: a review of the evidence, and methodological considerations","volume":"27","author":"Jonsson","year":"2009","journal-title":"Pharmacoeconomics"},{"issue":"5","key":"10.1016\/j.ijnurstu.2015.10.012_bib0065","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1002\/gps.1489","article-title":"Determinants of costs of care for patients with Alzheimer's disease","volume":"21","author":"J\u00f6nsson","year":"2006","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"1","key":"10.1016\/j.ijnurstu.2015.10.012_bib0115","first-page":"29","article-title":"The cost of informal care associated to incapacitating neurological disease having high prevalence in Spain","volume":"23","author":"Jorgensen","year":"2008","journal-title":"Neurologia"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0150","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1093\/geront\/10.1_Part_1.20","article-title":"Progress in development of the index of ADL","volume":"10","author":"Katz","year":"1970","journal-title":"Gerontologist"},{"issue":"2","key":"10.1016\/j.ijnurstu.2015.10.012_bib0165","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1176\/jnp.12.2.233","article-title":"Validation of the NPI-Q, a brief clinical form of the Neuropsychiatric Inventory","volume":"12","author":"Kaufer","year":"2000","journal-title":"J. Neuropsychiatry Clin. Neurosci."},{"issue":"6","key":"10.1016\/j.ijnurstu.2015.10.012_bib0275","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/gps.3864","article-title":"Dementia care costs and outcomes: a systematic review","volume":"28","author":"Knapp","year":"2013","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"5","key":"10.1016\/j.ijnurstu.2015.10.012_bib0175","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1111\/j.1600-0447.2011.01741.x","article-title":"Net costs of dementia by disease stage","volume":"124","author":"Leicht","year":"2011","journal-title":"Acta Psychiatr. Scand."},{"issue":"7","key":"10.1016\/j.ijnurstu.2015.10.012_bib0225","doi-asserted-by":"crossref","first-page":"e70018","DOI":"10.1371\/journal.pone.0070018","article-title":"Predictors of costs in dementia in a longitudinal perspective","volume":"8","author":"Leicht","year":"2013","journal-title":"PLoS ONE"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0045","series-title":"Gesti\u00f3n y Asistencia en demencias","article-title":"Gesti\u00f3n de costes en una Unidad de Demencia","author":"Lema","year":"2005"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0140","unstructured":"LEY 39\/2006, de 14 de diciembre, de Promoci\u00f3n de la Autonom\u00eda Personal y Atenci\u00f3n a las personas en situaci\u00f3n de dependencia, BOE 39\/2006. Sect. n\u00fam. 299."},{"issue":"12","key":"10.1016\/j.ijnurstu.2015.10.012_bib0055","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1212\/01.wnl.0000249311.80411.93","article-title":"Social-economic costs and quality of life of Alzheimer disease in the Canary Islands, Spain","volume":"67","author":"Lopez-Bastida","year":"2006","journal-title":"Neurology"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0015","series-title":"Enfermedad de Alzheimer y otras demencias","first-page":"29","article-title":"La demencia: concepto y epidemiolog\u00eda","author":"L\u00f3pez-Pousa","year":"2010"},{"issue":"20","key":"10.1016\/j.ijnurstu.2015.10.012_bib0105","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/S0025-7753(04)74381-X","article-title":"An\u00e1lisis de los costes de la enfermedad de Alzheimer en funci\u00f3n del deterioro cognitivo y funcional","volume":"122","author":"L\u00f3pez-Pousa","year":"2004","journal-title":"Med. Clin. (Barc.)"},{"issue":"4","key":"10.1016\/j.ijnurstu.2015.10.012_bib0240","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1177\/1533317511407481","article-title":"A review of the methods used to estimate the cost of Alzheimer's disease in the United States","volume":"26","author":"Mauskopf","year":"2011","journal-title":"Am. J. Alzheimer's Dis. Other Demen."},{"issue":"7","key":"10.1016\/j.ijnurstu.2015.10.012_bib0255","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1007\/s40266-013-0083-y","article-title":"Patterns and determinants of dementia pharmacotherapy in a population-based cohort of home care clients","volume":"30","author":"Maxwell","year":"2013","journal-title":"Drugs Aging"},{"issue":"7","key":"10.1016\/j.ijnurstu.2015.10.012_bib0210","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1002\/hec.1513","article-title":"The value of informal care a further investigation of the feasibility of contingent valuation in informal caregivers","volume":"19","author":"Meijer","year":"2010","journal-title":"Health Econ."},{"issue":"4","key":"10.1016\/j.ijnurstu.2015.10.012_bib0185","doi-asserted-by":"crossref","first-page":"358","DOI":"10.2174\/156720510791162430","article-title":"Cross sectional observational study on the societal costs of Alzheimer's disease","volume":"7","author":"Mesterton","year":"2010","journal-title":"Curr. Alzheimer Res."},{"issue":"1","key":"10.1016\/j.ijnurstu.2015.10.012_bib0145","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1176\/ajp.148.1.102","article-title":"Reliability of a standardized Mini-Mental State Examination compared with the traditional Mini-Mental State Examination","volume":"148","author":"Molloy","year":"1991","journal-title":"Am. J. Psychiatry"},{"issue":"3","key":"10.1016\/j.ijnurstu.2015.10.012_bib0250","doi-asserted-by":"crossref","first-page":"227","DOI":"10.2165\/00019053-200523030-00004","article-title":"The economic impact of neuropsychiatric symptoms in Alzheimer's disease: can drugs ease the burden?","volume":"23","author":"Murman","year":"2005","journal-title":"Pharmacoeconomics"},{"issue":"7","key":"10.1016\/j.ijnurstu.2015.10.012_bib0155","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1002\/gps.1724","article-title":"Time use and costs of institutionalised elderly persons with or without dementia: results from the Nordanstig cohort in the Kungsholmen Project\u2014a population based study in Sweden","volume":"22","author":"Nordberg","year":"2007","journal-title":"Int. J. Geriatr. Psychiatry"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0130","series-title":"El Sistema Nacional de Salud","author":"OCU","year":"2011"},{"issue":"3","key":"10.1016\/j.ijnurstu.2015.10.012_bib0005","first-page":"83","article-title":"Estimacion de los Costes de los cuidados informales asociados a enfermedades neurol\u00f3gicas de alta prevalencia en Espa\u00f1a","volume":"4","author":"Oliva","year":"2007","journal-title":"Pharmacoeconomics"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0230","article-title":"Economic valuation and determinants of informal care to people with Alzheimer's disease","author":"Pe\u00f1a-Longobardo","year":"2014","journal-title":"Eur. J. Health Econ."},{"issue":"5","key":"10.1016\/j.ijnurstu.2015.10.012_bib0270","doi-asserted-by":"crossref","first-page":"370","DOI":"10.7326\/0003-4819-148-5-200803040-00008","article-title":"Current pharmacologic treatment of dementia: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians","volume":"148","author":"Qaseem","year":"2008","journal-title":"Ann. Intern. Med."},{"issue":"4","key":"10.1016\/j.ijnurstu.2015.10.012_bib0090","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1600-0447.2009.01461.x","article-title":"Cost-of-illness studies of dementia: a systematic review focusing on stage dependency of costs","volume":"121","author":"Quentin","year":"2010","journal-title":"Acta Psychiatr. Scand."},{"issue":"3","key":"10.1016\/j.ijnurstu.2015.10.012_bib0180","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.jval.2012.02.003","article-title":"Exploring the relationship between Alzheimer's Disease Severity and Longitudinal Costs","volume":"15","author":"Rapp","year":"2012","journal-title":"Value Health"},{"issue":"February (2)","key":"10.1016\/j.ijnurstu.2015.10.012_bib0295","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/gps.4198","article-title":"The main cost drivers in dementia: a systematic review","volume":"30","author":"Schaller","year":"2015","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"6","key":"10.1016\/j.ijnurstu.2015.10.012_bib0290","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.jval.2011.04.005","article-title":"Costs of care for dementia patients in community setting: an analysis for mild and moderate disease stage","volume":"14","author":"Schwarzkopf","year":"2011","journal-title":"Value Health"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0125","series-title":"Anuario de Estad\u00edsticas Laborales","author":"Sistema Europeo de Estad\u00edsticas Integradas de Protecci\u00f3n Social (SEEPROS)","year":"2007"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0205","series-title":"Costs and Prices of Healthcare Services in The Netherlands: A Micro Costing Approach based on Case-vignettes","author":"Tan","year":"2006"},{"issue":"1","key":"10.1016\/j.ijnurstu.2015.10.012_bib0075","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1080\/13607860701366038","article-title":"The balance of care: reconfiguring services for older people with mental health problems","volume":"12","author":"Tucker","year":"2008","journal-title":"Aging Ment. Health"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0035","doi-asserted-by":"crossref","first-page":"201","DOI":"10.33588\/rn.5104.2010117","article-title":"Valor econ\u00f3mico anual de la asistencia informal en la enfermedad de Alzheimer","volume":"51","author":"Turr\u00f3-Garriga","year":"2010","journal-title":"Rev. Neurol."},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0080","first-page":"12","article-title":"A European study investigating patterns of transition from home care towards institutional dementia care: the protocol of a RightTimePlaceCare study","author":"Verbeek","year":"2012","journal-title":"BMC Med."},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0030","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/gps.1652","article-title":"Access to diagnostic evaluation and treatment for dementia in Europe","volume":"22","author":"Waldemar","year":"2007","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"1","key":"10.1016\/j.ijnurstu.2015.10.012_bib0170","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.archger.2006.03.001","article-title":"Validity of assessments of time \u2013 comparisons of direct observations and estimates of time by the use of the RUD (Resource Utilization in Dementia)-instrument","volume":"44","author":"Wimo","year":"2007","journal-title":"Arch. Gerontol. Geriatr."},{"issue":"5","key":"10.1016\/j.ijnurstu.2015.10.012_bib0100","doi-asserted-by":"crossref","first-page":"327","DOI":"10.2165\/00019053-200321050-00004","article-title":"Resource utilisation and cost analysis of memantine in patients with moderate to severe Alzheimer's disease","volume":"21","author":"Wimo","year":"2003","journal-title":"Pharmacoeconomics"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0040","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1002\/gps.2610","article-title":"The economic impact of dementia in Europe in 2008 cost estimates from the Eurocode project","volume":"26","author":"Wimo","year":"2011","journal-title":"Int. J. Geriatr. Psychiatry"},{"issue":"2","key":"10.1016\/j.ijnurstu.2015.10.012_bib0120","doi-asserted-by":"crossref","first-page":"385","DOI":"10.3233\/JAD-122392","article-title":"The GERAS Study: a prospective observational study of costs and resource. use in community dwellers with Alzheimer's disease in three European. Countries \u2013 study design and baseline findings","volume":"36","author":"Wimo","year":"2013","journal-title":"J. Alzheimer's Dis."},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0220","series-title":"Policy: World Medical Association Declaration of Helsinki. Ethical Principles for Medical Research Involving Human Subjects","author":"World Medical Association","year":"2008"},{"key":"10.1016\/j.ijnurstu.2015.10.012_bib0200","article-title":"Costs of care for people with dementia just before and after nursing home placement: primary data from 8 European countries","author":"W\u00fcbker","year":"2014","journal-title":"Eur. J. Health Econ."},{"issue":"2","key":"10.1016\/j.ijnurstu.2015.10.012_bib0050","doi-asserted-by":"crossref","first-page":"143","DOI":"10.2147\/ciia.2006.1.2.143","article-title":"Economic considerations in the management of Alzheimer's disease","volume":"1","author":"Zhu","year":"2006","journal-title":"Clin. Interv. Aging"}],"container-title":["International Journal of Nursing Studies"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020748915003296?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020748915003296?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T13:31:25Z","timestamp":1758115885000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020748915003296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3]]},"references-count":59,"alternative-id":["S0020748915003296"],"URL":"https:\/\/doi.org\/10.1016\/j.ijnurstu.2015.10.012","relation":{},"ISSN":["0020-7489"],"issn-type":[{"value":"0020-7489","type":"print"}],"subject":[],"published":{"date-parts":[[2016,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Direct and indirect costs and resource use in dementia care: A cross-sectional study in patients living at home","name":"articletitle","label":"Article Title"},{"value":"International Journal of Nursing Studies","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijnurstu.2015.10.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}