{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T01:54:15Z","timestamp":1773280455744,"version":"3.50.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2009,7,1]],"date-time":"2009-07-01T00:00:00Z","timestamp":1246406400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Obstetric Anesthesia"],"published-print":{"date-parts":[[2009,7]]},"DOI":"10.1016\/j.ijoa.2008.10.002","type":"journal-article","created":{"date-parts":[[2009,2,2]],"date-time":"2009-02-02T10:03:43Z","timestamp":1233569023000},"page":"258-261","source":"Crossref","is-referenced-by-count":63,"title":["Intravenous dexmedetomidine as an adjunct for labor analgesia and cesarean delivery anesthesia in a parturient with a tethered spinal cord"],"prefix":"10.1016","volume":"18","author":[{"given":"A.","family":"Palanisamy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.J.","family":"Klickovich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ramsay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.W.","family":"Ouyang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.C.","family":"Tsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijoa.2008.10.002_bib1","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.ijoa.2007.01.010","article-title":"Intravenous patient-controlled analgesia for labour: a survey of UK practice","volume":"16","author":"Saravanakumar","year":"2007","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.ijoa.2008.10.002_bib2","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1213\/01.ANE.0000136850.08972.07","article-title":"A multicenter randomized controlled trial comparing patient-controlled epidural with intravenous analgesia for pain relief in labor","volume":"99","author":"Halpern","year":"2004","journal-title":"Anesth Analg"},{"key":"10.1016\/j.ijoa.2008.10.002_bib3","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/0002-9378(89)90474-2","article-title":"Intravenous clonidine hydrochloride toxicity in pregnant ewes","volume":"160","author":"Eisenach","year":"1989","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.ijoa.2008.10.002_bib4","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.nec.2007.04.001","article-title":"Tethered cord syndrome","volume":"18","author":"Agarwalla","year":"2007","journal-title":"Neurosurg Clin N Am"},{"key":"10.1016\/j.ijoa.2008.10.002_bib5","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0959-289X(98)90005-X","article-title":"Neonatal effects of patient-controlled analgesia using fentanyl in labor","volume":"7","author":"Morley-Forster","year":"1998","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.ijoa.2008.10.002_bib6","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/00075198-200108000-00002","article-title":"Dexmedetomidine","volume":"7","author":"Coursin","year":"2001","journal-title":"Curr Opin Crit Care"},{"key":"10.1016\/j.ijoa.2008.10.002_bib7","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/00001503-200008000-00007","article-title":"A-2 adrenoreceptor anesthesia: a new paradigm","volume":"13","author":"Scholz","year":"2000","journal-title":"Curr Opin Anaesthesiol"},{"key":"10.1016\/j.ijoa.2008.10.002_bib8","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1345\/aph.1H314","article-title":"Dexmedetomidine: An updated review","volume":"41","author":"Gerlach","year":"2007","journal-title":"Ann Pharmacother"},{"key":"10.1016\/j.ijoa.2008.10.002_bib9","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1053\/j.sane.2006.01.004","article-title":"Dexmedetomidine sedation for awake fiberoptic intubation","volume":"25","author":"Unfer","year":"2006","journal-title":"Semin Anesth Periop Med Pain"},{"key":"10.1016\/j.ijoa.2008.10.002_bib10","first-page":"212","article-title":"Dexmedetomidine in general anesthesia for surgical treatment of cerebral aneurysm in pregnant patient with specific hypertensive disease of pregnancy: case report","volume":"55","author":"Souza de","year":"2005","journal-title":"Rev Bras Anestesiol"},{"key":"10.1016\/j.ijoa.2008.10.002_bib11","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1399-6576.1997.tb04685.x","article-title":"Transfer of clonidine and dexmedetomidine across the isolated perfused human placenta","volume":"41","author":"Ala-Kokko","year":"1997","journal-title":"Acta Anaesthesiol Scand"},{"key":"10.1016\/j.ijoa.2008.10.002_bib12","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1474-8673.1986.tb00654.x","article-title":"Evidence for medetomidine as a selective and potent agonist at alpha 2-adrenoreceptors","volume":"6","author":"Savola","year":"1986","journal-title":"J Auton Pharmacol"},{"key":"10.1016\/j.ijoa.2008.10.002_bib13","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1097\/00000542-199406000-00023","article-title":"Pharmacokinetics and pharmacodynamics of intraspinal dexmedetomidine in sheep","volume":"80","author":"Eisenach","year":"1994","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ijoa.2008.10.002_bib14","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1093\/bja\/71.2.294","article-title":"IV clonidine for post-extradural shivering in parturients: a preliminary study","volume":"71","author":"Capogna","year":"1993","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.ijoa.2008.10.002_bib15","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/0885-3924(94)90186-4","article-title":"Effect of clonidine on postpartum shivering after epidural analgesia: a randomized, controlled, double-blind study","volume":"9","author":"Mercadante","year":"1994","journal-title":"J Pain Symptom Manage"},{"key":"10.1016\/j.ijoa.2008.10.002_bib16","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/j.joms.2006.05.020","article-title":"Dexmedetomidine versus midazolam in outpatient third molar surgery","volume":"64","author":"Ustun","year":"2006","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijoa.2008.10.002_bib17","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1097\/00000542-200411000-00005","article-title":"Dexmedetomidine pharmacodynamics: part I: crossover comparison of the respiratory effects of dexmedetomidine and remifentanil in healthy volunteers","volume":"101","author":"Hsu","year":"2004","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ijoa.2008.10.002_bib18","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.ijoa.2004.11.004","article-title":"The in vitro effects of clonidine and dexmedetomidine on human myometrium","volume":"14","author":"Sia","year":"2005","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.ijoa.2008.10.002_bib19","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1097\/00000542-199212000-00013","article-title":"Effects of intravenous dexmedetomidine in humans. I. Sedation, ventilation, and metabolic rate","volume":"77","author":"Belleville","year":"1992","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ijoa.2008.10.002_bib20","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1097\/00000542-199212000-00014","article-title":"Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes","volume":"77","author":"Bloor","year":"1992","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ijoa.2008.10.002_bib21","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1097\/00000542-200008000-00016","article-title":"The effects of increasing plasma concentrations of dexmedetomidine in humans","volume":"93","author":"Ebert","year":"2000","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ijoa.2008.10.002_bib22","unstructured":"Angst M S, Ramaswamy B, Davies M F, Maze M. Comparative analgesic and mental effects of increasing plasma concentrations of dexmedetomidine and alfentanil in humans."},{"key":"10.1016\/j.ijoa.2008.10.002_bib23","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.ijoa.2008.03.005","article-title":"Proposer. Remifentanil patient-controlled analgesia should be routinely available for use in labour","volume":"17","author":"Hill","year":"2008","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.ijoa.2008.10.002_bib24","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1007\/BF03022956","article-title":"Remifentanil patient-controlled analgesia for labour: optimizing drug delivery regimens","volume":"54","author":"Balki","year":"2007","journal-title":"Can J Anesth"},{"key":"10.1016\/j.ijoa.2008.10.002_bib25","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.ijoa.2008.03.006","article-title":"Opposer. Remifentanil patient-controlled analgesia should be routinely available for use in labour","volume":"17","author":"Van de Velde","year":"2008","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.ijoa.2008.10.002_bib26","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/BF03018845","article-title":"A comparison of patient-controlled analgesia fentanyl and alfentanil for labour analgesia","volume":"47","author":"Morley-Forster","year":"2000","journal-title":"Can J Anaesth"}],"container-title":["International Journal of Obstetric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959289X0800160X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959289X0800160X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,22]],"date-time":"2018-12-22T03:22:20Z","timestamp":1545448940000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959289X0800160X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,7]]}},"alternative-id":["S0959289X0800160X"],"URL":"https:\/\/doi.org\/10.1016\/j.ijoa.2008.10.002","relation":{},"ISSN":["0959-289X"],"issn-type":[{"value":"0959-289X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,7]]}}}