{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T08:12:03Z","timestamp":1767859923496,"version":"3.49.0"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","obstetanesthesia.com","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Obstetric Anesthesia"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.ijoa.2016.09.001","type":"journal-article","created":{"date-parts":[[2016,9,13]],"date-time":"2016-09-13T01:47:40Z","timestamp":1473731260000},"page":"28-33","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Stimulation of contractions in pregnant human myometrium is associated with 5-HT3 receptors"],"prefix":"10.1016","volume":"28","author":[{"given":"H.","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Diao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Ni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q.","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.L.","family":"Wan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.S.","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X.M.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijoa.2016.09.001_b0005","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S0028-3908(99)00010-6","article-title":"A review of central 5-HT receptors and their function","volume":"38","author":"Barnes","year":"1999","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.ijoa.2016.09.001_b0010","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0091-3057(01)00746-8","article-title":"Molecular, pharmacological and functional diversity of 5-HT receptors","volume":"71","author":"Hoyer","year":"2002","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.ijoa.2016.09.001_b0015","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1136\/gut.2003.035568","article-title":"Pharmacology of serotonin: what a clinician should know","volume":"53","author":"De Ponti","year":"2004","journal-title":"Gut"},{"key":"10.1016\/j.ijoa.2016.09.001_b0020","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.cbpc.2014.05.006","article-title":"Serotonin regulates contractile activity of the uterus in non-pregnant rabbits","volume":"165","author":"Lychkova","year":"2014","journal-title":"Comp Biochem Physiol C Toxicol Pharmacol"},{"key":"10.1016\/j.ijoa.2016.09.001_b0025","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1093\/molehr\/gag061","article-title":"Investigation of the role of the serotonergic activity of certain subtype-selective \u03b11A antagonists in the relaxant effect on the pregnant rat uterus in vitro","volume":"9","author":"Miha\u00e1lyi","year":"2003","journal-title":"Molecular Human Reproduction"},{"key":"10.1016\/j.ijoa.2016.09.001_b0030","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1016\/S0022-3565(25)20915-6","article-title":"Role of 5-HT2 receptors in serotonin-induced contractions of nonvascular smooth muscle","volume":"232","author":"Cohen","year":"1985","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.ijoa.2016.09.001_b0035","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1113\/jphysiol.2007.129726","article-title":"Increased 5-HT contractile response in late pregnant rat myometrium is associated with a higher density of 5-HT2A receptors","volume":"581","author":"Minosyan","year":"2007","journal-title":"J Physiol"},{"key":"10.1016\/j.ijoa.2016.09.001_b0040","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1124\/jpet.108.143040","article-title":"Characterization of serotonin receptors in pregnant human myometrium","volume":"328","author":"Cordeaux","year":"2009","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.ijoa.2016.09.001_b0045","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1124\/jpet.105.100172","article-title":"Pharmacological evidence for a functional serotonin-2B receptor in a human uterine smooth muscle cell line","volume":"317","author":"Kelly","year":"2006","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.ijoa.2016.09.001_b0050","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.ejphar.2008.10.019","article-title":"Excitatory and inhibitory 5-hydroxytryptamine (5-HT) receptors expressed in the isolated porcine uterine muscles","volume":"600","author":"Nakamura","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.ijoa.2016.09.001_b0055","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S0014-2999(01)01504-7","article-title":"5-HT(7) receptor and beta(2)-adrenoceptor share in the inhibition of porcine uterine contractility in a muscle layer-dependent manner","volume":"433","author":"Kitazawa","year":"2001","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.ijoa.2016.09.001_b0060","first-page":"361","article-title":"Some studies on the 5-hydroxytryptamine receptors in the isolated rat uterus","volume":"31","author":"Ononiwu","year":"2002","journal-title":"Afr J Med Med Sci"},{"key":"10.1016\/j.ijoa.2016.09.001_b0065","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.ijoa.2014.11.003","article-title":"5-HT3 receptor antagonists do not alter spontaneous contraction of pregnant myometrium in vitro","volume":"24","author":"Lin","year":"2015","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.ijoa.2016.09.001_b0070","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.ijoa.2013.11.004","article-title":"Relaxant effects of metoclopramide and magnesium sulfate on isolated pregnant myometrium: an in vitro study","volume":"23","author":"Tang","year":"2014","journal-title":"Int J Obstet Anesth"},{"key":"10.1016\/j.ijoa.2016.09.001_b0075","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1097\/ALN.0b013e318297d347","article-title":"Oxytocin pretreatment attenuates oxytocin-induced contractions in human myometrium in vitro","volume":"119","author":"Balki","year":"2013","journal-title":"Anesthesiology"},{"key":"10.1016\/j.ijoa.2016.09.001_b0080","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0022-3565(24)37801-2","article-title":"Oxytocin inhibits the uptake of serotonin into uterine mast cells","volume":"287","author":"Rudolph","year":"1998","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.ijoa.2016.09.001_b0085","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.3748\/wjg.v10.i18.2723","article-title":"Ovarian hormone modulates 5-hydroxytryptamine 3 receptors mRNA expression in rat colon with restraint stress-induced bowel dysfunction","volume":"10","author":"Li","year":"2004","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.ijoa.2016.09.001_b0090","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/s00210-007-0173-7","article-title":"Demonstration of 5-HT(3) receptor function and expression in the mouse bladder","volume":"375","author":"Chetty","year":"2007","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.1016\/j.ijoa.2016.09.001_b0095","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1002\/jnr.20894","article-title":"Serotonin induces the increase in intracellular Ca2+ that enhances neurite outgrowth in PC12 cells via activation of 5-HT3 receptors and voltage-gated calcium channels","volume":"84","author":"Homma","year":"2006","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.ijoa.2016.09.001_b0100","doi-asserted-by":"crossref","first-page":"e104718","DOI":"10.1371\/journal.pone.0104718","article-title":"Serotonin 5-HT3 receptor-mediated vomiting occurs via the activation of Ca2+\/CaMKII-dependent ERK1\/2 signaling in the least shrew (Cryptotis parva)","volume":"9","author":"Zhong","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.ijoa.2016.09.001_b0105","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.tips.2012.12.002","article-title":"Recent developments in 5-HT3 receptor pharmacology","volume":"34","author":"Thompson","year":"2013","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.ijoa.2016.09.001_b0110","doi-asserted-by":"crossref","first-page":"5135","DOI":"10.3390\/molecules19045135","article-title":"The effect of DA-9701 on 5-hydroxytryptamine-induced contraction of feline esophageal smooth muscle cells","volume":"19","author":"Oh","year":"2014","journal-title":"Molecules"},{"key":"10.1016\/j.ijoa.2016.09.001_b0115","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0031-6997(25)06783-3","article-title":"International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin)","volume":"46","author":"Hoyer","year":"1994","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.ijoa.2016.09.001_b0120","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1124\/jpet.111.190769","article-title":"VUF10166, a novel compound with differing activities at 5-HT(3)A and 5-HT(3)AB receptors","volume":"341","author":"Thompson","year":"2012","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.ijoa.2016.09.001_b0125","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1016\/j.bpj.2009.12.4313","article-title":"Agonists and antagonists bind to an A-A interface in the heteromeric 5-HT3AB receptor","volume":"98","author":"Lochner","year":"2010","journal-title":"Biophys J"},{"key":"10.1016\/j.ijoa.2016.09.001_b0130","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0014-2999(88)90255-5","article-title":"Ergometrine\u2013a partial agonist at 5-HT receptors in the uterus isolated from the oestrogen-primed rat","volume":"158","author":"Hollingsworth","year":"1988","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.ijoa.2016.09.001_b0135","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1016\/S0149-2918(03)80128-5","article-title":"Effects of aprepitant on the pharmacokinetics of ondansetron and granisetron in healthy subjects","volume":"25","author":"Blum","year":"2003","journal-title":"Clinical therapeutics"}],"container-title":["International Journal of Obstetric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959289X16300711?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0959289X16300711?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T18:20:32Z","timestamp":1749579632000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0959289X16300711"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":27,"alternative-id":["S0959289X16300711"],"URL":"https:\/\/doi.org\/10.1016\/j.ijoa.2016.09.001","relation":{},"ISSN":["0959-289X"],"issn-type":[{"value":"0959-289X","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stimulation of contractions in pregnant human myometrium is associated with 5-HT3 receptors","name":"articletitle","label":"Article Title"},{"value":"International Journal of Obstetric Anesthesia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijoa.2016.09.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}