{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T13:10:52Z","timestamp":1760274652081,"version":"build-2065373602"},"reference-count":31,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["201808510166"],"award-info":[{"award-number":["201808510166"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijoms.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Oral and Maxillofacial Surgery"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.ijom.2022.02.004","type":"journal-article","created":{"date-parts":[[2022,2,24]],"date-time":"2022-02-24T23:24:39Z","timestamp":1645745079000},"page":"1205-1210","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Prevalence and characteristics of systemic conditions in patients undergoing orthognathic surgery: a retrospective study"],"prefix":"10.1016","volume":"51","author":[{"given":"J.","family":"Ver Berne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6309-3791","authenticated-orcid":false,"given":"E.","family":"Shaheen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Politis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Peeters","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3461-0363","authenticated-orcid":false,"given":"R.","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijom.2022.02.004_bib0005","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1089\/ten.teb.2016.0370","article-title":"Diabetes mellitus and bone regeneration: a systematic review and meta-analysis of animal studies","volume":"23","author":"Camargo","year":"2017","journal-title":"Tissue Eng Part B Rev"},{"key":"10.1016\/j.ijom.2022.02.004_bib0010","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3389\/fendo.2018.00006","article-title":"The impact of type 2 diabetes on bone fracture healing","volume":"9","author":"Marin","year":"2018","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.ijom.2022.02.004_bib0015","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1097\/MBC.0000000000000330","article-title":"Haemophilia A and B as a cause for secondary osteoporosis and increased fracture risk","volume":"26","author":"Anagnostis","year":"2015","journal-title":"Blood Coagul Fibrinolysis"},{"key":"10.1016\/j.ijom.2022.02.004_bib0020","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.1002\/art.23683","article-title":"Bone density, structure, and strength in juvenile idiopathic arthritis: importance of disease severity and muscle deficits","volume":"58","author":"Burnham","year":"2008","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.ijom.2022.02.004_bib0025","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.12998\/wjcc.v7.i15.1908","article-title":"Bone alterations in inflammatory bowel diseases","volume":"7","author":"Sgambato","year":"2019","journal-title":"World J Clin Cases"},{"key":"10.1016\/j.ijom.2022.02.004_bib0030","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.oooo.2015.03.004","article-title":"Bone mineral density and mandibular advancement as contributing factors for postoperative relapse after orthognathic surgery in patients with preoperative idiopathic condylar resorption: a prospective study with preliminary 1-year follow-up","volume":"120","author":"Yang","year":"2015","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.ijom.2022.02.004_bib0035","doi-asserted-by":"crossref","first-page":"e678","DOI":"10.1097\/SCS.0000000000003064","article-title":"Effect of osteoporosis on bone density of orthognathic osteotomy sites in maxillofacial region","volume":"27","author":"On","year":"2016","journal-title":"J Craniofac Surg"},{"key":"10.1016\/j.ijom.2022.02.004_bib0040","series-title":"Handbook of orthodontics","first-page":"147","author":"Moyers","year":"1988"},{"key":"10.1016\/j.ijom.2022.02.004_bib0045","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/nrrheum.2011.68","article-title":"Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions","volume":"7","author":"Mellins","year":"2011","journal-title":"Nat Rev Rheumatol"},{"key":"10.1016\/j.ijom.2022.02.004_bib0050","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1093\/ejo\/cjn085","article-title":"Variation in dentofacial morphology and occlusion in juvenile idiopathic arthritis subjects: a case\u2013control study","volume":"31","author":"Hu","year":"2009","journal-title":"Eur J Orthod"},{"key":"10.1016\/j.ijom.2022.02.004_bib0055","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s11102-016-0772-8","article-title":"Acromegaly: clinical features at diagnosis","volume":"20","author":"Vilar","year":"2017","journal-title":"Pituitary"},{"year":"2010","series-title":"Dorland\u2019s illustrated medical dictionary","author":"Dorland","key":"10.1016\/j.ijom.2022.02.004_bib0060"},{"year":"2018","series-title":"Chronische ziekten en aandoeningen","author":"Van Der Heyden","key":"10.1016\/j.ijom.2022.02.004_bib0065"},{"key":"10.1016\/j.ijom.2022.02.004_bib0070","doi-asserted-by":"crossref","first-page":"90","DOI":"10.4274\/balkanmedj.2017.0111","article-title":"Juvenile idiopathic arthritis","volume":"34","author":"Barut","year":"2017","journal-title":"Balkan Med J"},{"key":"10.1016\/j.ijom.2022.02.004_bib0075","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1086\/345996","article-title":"Connective tissue and its heritable disorders: molecular, genetic, and medical aspects","volume":"72","author":"Wilcox","year":"2003","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ijom.2022.02.004_bib0080","doi-asserted-by":"crossref","first-page":"31365","DOI":"10.1136\/bmjopen-2019-031365","article-title":"Diagnosed prevalence of Ehlers\u2013Danlos syndrome and hypermobility spectrum disorder in Wales, UK: a national electronic cohort study and case\u2013control comparison","volume":"9","author":"Demmler","year":"2019","journal-title":"BMJ Open"},{"key":"10.1016\/j.ijom.2022.02.004_bib0085","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1016\/S0140-6736(17)32448-0","article-title":"Worldwide incidence and prevalence of inflammatory bowel disease in the 21st century: a systematic review of population-based studies","volume":"390","author":"Ng","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.ijom.2022.02.004_bib0090","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s13023-020-1310-3","article-title":"Neurofibromatosis 1 French national guidelines based on an extensive literature review since 1966","volume":"15","author":"Bergqvist","year":"2020","journal-title":"Orphanet J Rare Dis"},{"key":"10.1016\/j.ijom.2022.02.004_bib0095","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.gde.2007.04.006","article-title":"Marfan syndrome: from molecular pathogenesis to clinical treatment","volume":"17","author":"Ramirez","year":"2007","journal-title":"Curr Opin Genet Dev"},{"key":"10.1016\/j.ijom.2022.02.004_bib0100","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.3389\/fphys.2017.01038","article-title":"Update on 13 syndromes affecting craniofacial and dental structures","volume":"8","author":"Bartzela","year":"2017","journal-title":"Front Physiol"},{"key":"10.1016\/j.ijom.2022.02.004_bib0105","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/s41574-019-0304-5","article-title":"Role of thyroid hormones in craniofacial development","volume":"16","author":"Leitch","year":"2020","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.ijom.2022.02.004_bib0110","doi-asserted-by":"crossref","first-page":"43220","DOI":"10.1038\/srep43220","article-title":"Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia","volume":"7","author":"Lee","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.ijom.2022.02.004_bib0115","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.ajhg.2012.02.005","article-title":"Bent bone dysplasia-FGFR2 type, a distinct skeletal disorder, has deficient canonical FGF signaling","volume":"90","author":"Merrill","year":"2012","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.ijom.2022.02.004_bib0120","doi-asserted-by":"crossref","first-page":"314","DOI":"10.2478\/v10039-012-0036-4","article-title":"Evidence that FGFR1 loss-of-function mutations may cause variable skeletal malformations in patients with Kallmann syndrome","volume":"57","author":"Jarzabek","year":"2012","journal-title":"Adv Med Sci"},{"key":"10.1016\/j.ijom.2022.02.004_bib0125","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1177\/0022034515581643","article-title":"Candidate gene analyses of skeletal variation in malocclusion","volume":"94","author":"Da Fontoura","year":"2015","journal-title":"J Dent Res"},{"key":"10.1016\/j.ijom.2022.02.004_bib0130","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.3390\/cells9112365","article-title":"Neurofibromin structure, functions and regulation","volume":"9","author":"Bergoug","year":"2020","journal-title":"Cells"},{"key":"10.1016\/j.ijom.2022.02.004_bib0135","doi-asserted-by":"crossref","first-page":"3910","DOI":"10.1093\/hmg\/ddr310","article-title":"Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I","volume":"20","author":"Wang","year":"2011","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.ijom.2022.02.004_bib0140","doi-asserted-by":"crossref","first-page":"4818","DOI":"10.1093\/hmg\/ddt333","article-title":"Hyperactive Ras\/MAPK signaling is critical for tibial nonunion fracture in neurofibromin-deficient mice","volume":"22","author":"Sharma","year":"2013","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.ijom.2022.02.004_bib0145","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1002\/ajmg.a.31754","article-title":"Associations of osseous abnormalities in neurofibromatosis","volume":"143","author":"Alwan","year":"2007","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.ijom.2022.02.004_bib0150","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/s00296-016-3625-x","article-title":"Bone mineral density is decreased in fibromyalgia syndrome: a systematic review and meta-analysis","volume":"37","author":"Upala","year":"2017","journal-title":"Rheumatol Int"},{"key":"10.1016\/j.ijom.2022.02.004_bib0155","first-page":"340","article-title":"Is the Behcet\u2019s disease a risk factor for osteoporosis and is relation to cytokines?","volume":"111","author":"Kirnap","year":"2010","journal-title":"Bratisl Lek Listy"}],"container-title":["International Journal of Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S090150272200039X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S090150272200039X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T12:36:53Z","timestamp":1760272613000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S090150272200039X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["S090150272200039X"],"URL":"https:\/\/doi.org\/10.1016\/j.ijom.2022.02.004","relation":{},"ISSN":["0901-5027"],"issn-type":[{"type":"print","value":"0901-5027"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevalence and characteristics of systemic conditions in patients undergoing orthognathic surgery: a retrospective study","name":"articletitle","label":"Article Title"},{"value":"International Journal of Oral and Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijom.2022.02.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}