{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:33:21Z","timestamp":1790858001512,"version":"4.1.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001732","name":"Danmarks Grundforskningsfond","doi-asserted-by":"publisher","award":["DNRF121"],"award-info":[{"award-number":["DNRF121"]}],"id":[{"id":"10.13039\/501100001732","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","ijoms.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Oral and Maxillofacial Surgery"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1016\/j.ijom.2025.10.002","type":"journal-article","created":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T01:41:37Z","timestamp":1761183697000},"page":"373-384","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Patient perceptions of recovery following surgical removal of an impacted mandibular third molar and application of advanced platelet-rich fibrin: a prospective randomized controlled clinical trial"],"prefix":"10.1016","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3726-4267","authenticated-orcid":false,"given":"T.","family":"Starch-Jensen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1331-129X","authenticated-orcid":false,"given":"R.","family":"Giordano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.M.","family":"Alsadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2644-4115","authenticated-orcid":false,"given":"N.H.","family":"Bruun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Arendt-Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijom.2025.10.002_bib1","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1007\/s11136-018-1889-1","article-title":"Third molar removal and its impact on quality of life: systematic review and meta-analysis","volume":"27","author":"Duarte-Rodrigues","year":"2018","journal-title":"Qual Life Res"},{"key":"10.1016\/j.ijom.2025.10.002_bib2","first-page":"e233","article-title":"Patient morbidity after impacted third molar extraction with different flap designs. A systematic review and meta-analysis","volume":"25","author":"Glera-Su\u00e1rez","year":"2020","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"10.1016\/j.ijom.2025.10.002_bib3","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/adj.12526","article-title":"Postoperative interventions to reduce inflammatory complications after third molar surgery: review of the current evidence","volume":"62","author":"Cho","year":"2017","journal-title":"Aust Dent J"},{"key":"10.1016\/j.ijom.2025.10.002_bib4","doi-asserted-by":"crossref","first-page":"2591","DOI":"10.1111\/bcp.15241","article-title":"Postoperative administration of ketorolac compared to other drugs for pain control after third molar surgery: a meta-analysis of double-blind, randomized, clinical trials","volume":"88","author":"Isiordia-Espinoza","year":"2022","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.ijom.2025.10.002_bib5","doi-asserted-by":"crossref","first-page":"239","DOI":"10.5005\/jp-journals-10024-1041","article-title":"Pain levels after third molar surgical removal: an evaluation of predictive variables","volume":"12","author":"Bortoluzzi","year":"2011","journal-title":"J Contemp Dent Pract"},{"key":"10.1016\/j.ijom.2025.10.002_bib6","doi-asserted-by":"crossref","first-page":"938","DOI":"10.4103\/2141-9248.144919","article-title":"Indications and risk factors for complications of lower third molar surgery in a Nigerian teaching hospital","volume":"4","author":"Osunde","year":"2014","journal-title":"Ann Med Health Sci Res"},{"key":"10.1016\/j.ijom.2025.10.002_bib7","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/j.joms.2003.04.001","article-title":"Types, frequencies, and risk factors for complications after third molar extraction","volume":"61","author":"Bui","year":"2003","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib8","doi-asserted-by":"crossref","first-page":"e376","DOI":"10.4317\/medoral.16.e376","article-title":"Factors associated with complications of removal of third molars: a transversal study","volume":"16","author":"Barbosa-Rebellato","year":"2011","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"10.1016\/j.ijom.2025.10.002_bib9","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/sj.bdj.4809930","article-title":"Changes in life quality following third molar surgery\u2014the immediate postoperative period","volume":"194","author":"McGrath","year":"2003","journal-title":"Br Dent J"},{"key":"10.1016\/j.ijom.2025.10.002_bib10","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1016\/j.joms.2006.05.030","article-title":"Dental anxiety before removal of a third molar and association with general trait anxiety","volume":"64","author":"Lago-M\u00e9ndez","year":"2006","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib11","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1016\/j.joms.2008.12.041","article-title":"Effect of third molar surgery on oral health-related quality of life in the first postoperative week using Dutch version of oral health impact profile-14","volume":"67","author":"van Wijk","year":"2009","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib12","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.joms.2016.09.023","article-title":"Does psychological profile influence third molar extraction and postoperative pain?","volume":"75","author":"Gonz\u00e1lez-Mart\u00ednez","year":"2017","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib13","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.jcms.2023.09.018","article-title":"Patient\u2019s perception of recovery following surgical removal of mandibular third molars. A prospective European multi-center study","volume":"51","author":"Starch-Jensen","year":"2023","journal-title":"J Craniomaxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib14","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/joor.12789","article-title":"Therapeutic efficacy of cryotherapy on facial swelling, pain, trismus and quality of life after surgical removal of mandibular third molars: a systematic review","volume":"46","author":"Larsen","year":"2019","journal-title":"J Oral Rehabil"},{"key":"10.1016\/j.ijom.2025.10.002_bib15","doi-asserted-by":"crossref","DOI":"10.5037\/jomr.2018.9201","article-title":"Different dosages of corticosteroid and routes of administration in mandibular third molar surgery: a systematic review","volume":"9","author":"Larsen","year":"2018","journal-title":"J Oral Maxillofac Res"},{"key":"10.1016\/j.ijom.2025.10.002_bib16","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1016\/j.jcms.2021.06.006","article-title":"Use of low-level laser therapy to reduce postoperative pain, edema, and trismus following third molar surgery: a systematic review and meta-analysis","volume":"49","author":"Duarte de Oliveira","year":"2021","journal-title":"J Craniomaxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib17","doi-asserted-by":"crossref","first-page":"5139","DOI":"10.1007\/s00784-021-04069-2","article-title":"Can Kinesio taping improve discomfort after mandibular third molar surgery? A systematic review and meta-analysis","volume":"25","author":"Wang","year":"2021","journal-title":"Clin Oral Investig"},{"key":"10.1016\/j.ijom.2025.10.002_bib18","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s10006-021-01025-y","article-title":"Does Kinesio taping reduce pain, swelling, and trismus after mandibular third molar surgery? A systematic review and meta-analysis","volume":"26","author":"Firoozi","year":"2022","journal-title":"Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib19","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.ijom.2018.07.016","article-title":"Acupuncture on anxiety and inflammatory events following surgery of mandibular third molars: a split-mouth, randomized, triple-blind clinical trial","volume":"48","author":"Armond","year":"2019","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib20","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1186\/2008-2231-21-59","article-title":"Effectiveness of green tea mouthwash in postoperative pain control following surgical removal of impacted third molars: double blind randomized clinical trial","volume":"21","author":"Eshghpour","year":"2013","journal-title":"Daru"},{"key":"10.1016\/j.ijom.2025.10.002_bib21","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/s00784-020-03522-y","article-title":"Postoperative effects of intra-alveolar application of 0.2% chlorhexidine or 1% hyaluronic acid bioadhesive gels after mandibular third molar extraction: a double-blind randomized controlled clinical trial","volume":"25","author":"Mu\u00f1oz-C\u00e1mara","year":"2021","journal-title":"Clin Oral Investig"},{"key":"10.1016\/j.ijom.2025.10.002_bib22","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1007\/s00784-017-2133-z","article-title":"Use of platelet-rich fibrin in regenerative dentistry: a systematic review","volume":"21","author":"Miron","year":"2017","journal-title":"Clin Oral Investig"},{"key":"10.1016\/j.ijom.2025.10.002_bib23","doi-asserted-by":"crossref","first-page":"482","DOI":"10.3390\/ijms25010482","article-title":"Biological and cellular properties of advanced platelet-rich fibrin (A-PRF) compared to other platelet concentrates: systematic review and meta-analysis","volume":"25","author":"Pereira","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.ijom.2025.10.002_bib24","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1016\/j.ijom.2021.11.014","article-title":"The use of advanced platelet-rich fibrin after surgical removal of mandibular third molars: a systematic review and meta-analysis","volume":"51","author":"Vitenson","year":"2022","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib25","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/j.joms.2022.03.011","article-title":"Do the new protocols of platelet-rich fibrin centrifugation allow better control of postoperative complications and healing after surgery of impacted lower third molar? A systematic review and meta-analysis","volume":"80","author":"Ramos","year":"2022","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib26","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.ijom.2020.08.014","article-title":"Effect of platelet-rich fibrin on the control of alveolar osteitis, pain, trismus, soft tissue healing, and swelling following mandibular third molar surgery: an updated systematic review and meta-analysis","volume":"50","author":"Zhu","year":"2021","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib27","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1186\/s12903-019-0824-3","article-title":"Impact of platelet-rich fibrin on mandibular third molar surgery recovery: a systematic review and meta-analysis","volume":"19","author":"Xiang","year":"2019","journal-title":"BMC Oral Health"},{"key":"10.1016\/j.ijom.2025.10.002_bib28","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1016\/j.ijom.2017.04.006","article-title":"Evaluation of postoperative complications after mandibular third molar surgery with the use of platelet-rich fibrin: a systematic review and meta-analysis","volume":"46","author":"Canellas","year":"2017","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib29","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1016\/j.joms.2021.07.006","article-title":"Application of platelet-rich fibrin derivatives for mandibular third molar extraction related post-operative sequelae: a systematic review and network meta-analysis","volume":"79","author":"Bao","year":"2021","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib30","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.joms.2007.09.011","article-title":"Evaluation of intraexaminer and interexaminer agreement on classifying lower third molars according to the systems of Pell and Gregory and of Winter","volume":"66","author":"Almendros-Marqu\u00e9s","year":"2008","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib31","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1111\/j.1600-0528.1997.tb00941.x","article-title":"Derivation and validation of a short-form oral health impact profile","volume":"25","author":"Slade","year":"1997","journal-title":"Commun Dent Oral Epidemiol"},{"key":"10.1016\/j.ijom.2025.10.002_bib32","first-page":"3","article-title":"Development and evaluation of the oral health impact profile","volume":"11","author":"Slade","year":"1994","journal-title":"Commun Dent Health"},{"key":"10.1016\/j.ijom.2025.10.002_bib33","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1016\/j.tripleo.2005.07.011","article-title":"Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part IV: clinical effects on tissue healing","volume":"101","author":"Choukroun","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.ijom.2025.10.002_bib34","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.tripleo.2005.07.012","article-title":"Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part V: histologic evaluations of PRF effects on bone allograft maturation in sinus lift","volume":"101","author":"Choukroun","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.ijom.2025.10.002_bib35","first-page":"121","article-title":"Effectiveness of soft laser treatment in periodontal surgery","volume":"43","author":"Masse","year":"1993","journal-title":"Int Dent J"},{"key":"10.1016\/j.ijom.2025.10.002_bib36","first-page":"e759","article-title":"Quality of life after upper third molar removal: a prospective longitudinal study","volume":"22","author":"Avellaneda-Gimeno","year":"2017","journal-title":"Med Oral Patol Oral Cir Bucal"},{"key":"10.1016\/j.ijom.2025.10.002_bib37","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1007\/s00784-016-1719-1","article-title":"Comparative release of growth factors from PRP, PRF, and advanced-PRF","volume":"20","author":"Kobayashi","year":"2016","journal-title":"Clin Oral Investig"},{"key":"10.1016\/j.ijom.2025.10.002_bib38","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.jcms.2020.01.016","article-title":"Preemptive use of oral nonsteroidal anti-inflammatory drugs for the relief of inflammatory events after surgical removal of lower third molars: a systematic review with meta-analysis of placebo-controlled randomized clinical trials","volume":"48","author":"Cetira Filho","year":"2020","journal-title":"J Craniomaxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib39","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.jormas.2020.02.004","article-title":"Evaluation of the effects of concentrated growth factors or advanced platelet rich-fibrin on postoperative pain, edema, and trismus following lower third molar removal: a randomized controlled clinical trial","volume":"121","author":"Torul","year":"2020","journal-title":"J Stomatol Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib40","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.joms.2024.02.003","article-title":"Effect of advanced platelet-rich fibrin (A-PRF) on postoperative level of pain and swelling following third molar surgery","volume":"82","author":"Praganta","year":"2024","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib41","article-title":"Effectiveness of advanced platelet-rich fibrin on postoperative sequelae for impacted mandibular third molar surgery: a prospective study","volume":"16","author":"Mathialagan Kalai Selvam","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.ijom.2025.10.002_bib42","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.5005\/jp-journals-10024-2666","article-title":"Effect of advanced platelet-rich fibrin on wound healing after third molar extraction: a split-mouth randomized double-blind study","volume":"20","author":"Zahid","year":"2019","journal-title":"J Contemp Dent Pract"},{"key":"10.1016\/j.ijom.2025.10.002_bib43","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jormas.2020.04.008","article-title":"Advanced-PRF: clinical evaluation in impacted mandibular third molar sockets","volume":"122","author":"Gupta","year":"2021","journal-title":"J Stomatol Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib44","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/j.joms.2024.02.014","article-title":"Do platelet-rich concentrates improve the adverse sequelae of impacted mandibular third molar removal?","volume":"82","author":"Yari","year":"2024","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.ijom.2025.10.002_bib45","doi-asserted-by":"crossref","DOI":"10.1155\/2023\/1883460","article-title":"The influence of the hyaluronic acid gel on the postoperative sequelae following surgical removal of the impacted mandibular third molar in comparison with the A-PRF: a randomized controlled trial","volume":"2023","author":"Al-Saadi","year":"2023","journal-title":"Int J Biomater"},{"key":"10.1016\/j.ijom.2025.10.002_bib46","doi-asserted-by":"crossref","first-page":"546","DOI":"10.4103\/njcp.njcp_473_18","article-title":"Comparison of the effect of advanced platelet-rich fibrin and leukocyte- and platelet-rich fibrin on outcomes after removal of impacted mandibular third molar: a randomized split-mouth study","volume":"22","author":"Caymaz","year":"2019","journal-title":"Niger J Clin Pract"},{"key":"10.1016\/j.ijom.2025.10.002_bib47","doi-asserted-by":"crossref","first-page":"126","DOI":"10.4236\/abb.2013.41A018","article-title":"Complications of venepuncture","volume":"4","author":"Buowari","year":"2013","journal-title":"Adv Biosci Biotechnol"}],"container-title":["International Journal of Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0901502725014699?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0901502725014699?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T10:24:23Z","timestamp":1773915863000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0901502725014699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["S0901502725014699"],"URL":"https:\/\/doi.org\/10.1016\/j.ijom.2025.10.002","relation":{},"ISSN":["0901-5027"],"issn-type":[{"value":"0901-5027","type":"print"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Patient perceptions of recovery following surgical removal of an impacted mandibular third molar and application of advanced platelet-rich fibrin: a prospective randomized controlled clinical trial","name":"articletitle","label":"Article Title"},{"value":"International Journal of Oral and Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijom.2025.10.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc. on behalf of International Association of Oral and Maxillofacial Surgeons.","name":"copyright","label":"Copyright"}]}}