{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:28:25Z","timestamp":1786728505112,"version":"build-2736575974"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T00:00:00Z","timestamp":1558915200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"CSF"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2020,9]]},"abstract":"\n Objectives:<\/jats:title>\n Group B streptococcus (GBS) infection is a serious disease that continues to cause high morbidity and mortality. It is one of the leading cause of sepsis; particularly meningitis, in infants and young children all around the world. In this study, we aim to identify the incidence of GBS sepsis in Omani infants less than 3 months of age who were born at Royal Hospital and who presented with clinical sepsis and positive culture. In addition, we aim to describe the clinical presentation and complications noted on admission and then on follow-up visit.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n This is an observational retrospective chart review study. It included all Omani infants (0\u20133 months) who were diagnosed to have GBS sepsis\/meningitis from 2006 to 2016 at the Royal Hospital, Muscat, Sultanate of Oman.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n There were 83,000 live births in the Royal Hospital over a period of 10 years. Thirty-eight babies had culture proven GBS infection, with an overall incidence rate of neonatal GBS of 0.46 per 1000 live births with 95% confidence intervals. There were no significant variations in the annual rates of infection during the study period, ranging from around 1\u20137 cases per year. Additional 5 cases of GBS sepsis presented to Royal Hospital are either through Emergency Department or as referrals from other hospitals, giving us a total of 43 cases of proven GBS infections. Out of the 43 cases, 8 were born prematurely (19%), either before (<34 weeks, n = 2) or during (34\u201336 weeks, n = 6). Term babies were 35 out of 43 with percentage of 81% of the total. Three died, resulting in a case mortality of 7.0%.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Our GBS incidence is comparable to that of screened population internationally. At the time being, with the best available results, maternal screening might not seem cost effective in our current settings. A cost effective study is required before implemented a national screening programme in the Country. However, this research will definitely help in the process of any future plans of implantation of new guidelines, as it can be used as leading point for future prospective studies.<\/jats:p>\n <\/jats:sec>","DOI":"10.1016\/j.ijpam.2019.05.002","type":"journal-article","created":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T02:24:54Z","timestamp":1559096694000},"page":"136-139","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Incidence and outcome of group B streptococcal invasive disease in Omani infants"],"prefix":"10.4103","volume":"7","author":[{"given":"Eman AL.","family":"Masroori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wafa Bani","family":"Uraba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hilal Al","family":"Hashami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-8-20240319","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.clp.2014.10.004","article-title":"Bacterial meningitis in the infant","volume":"42","author":"Ku","year":"2015","journal-title":"Clin Perinatol"},{"key":"R5-8-20240319","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.ijid.2016.12.006","article-title":"Culture-proven early-onset neonatal sepsis in Arab states in the Gulf region: two-year prospective study","volume":"55","author":"Hammoud","year":"2017","journal-title":"Int J Infect Dis"},{"key":"R7-8-20240319","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/jp.2008.115","article-title":"Continued early onset group B streptococcal infections in the era of intrapartum prophylaxis","volume":"29","author":"Pulver","year":"2008","journal-title":"J Perinatol"},{"key":"R8-8-20240319","doi-asserted-by":"crossref","first-page":"D20","DOI":"10.1016\/j.vaccine.2012.11.056","article-title":"VeraniIntrapartum antibiotic prophylaxis for the prevention of perinatal group B streptococcal disease: experience in the United States and implications for a potential group B streptococcal vaccine","volume":"31","author":"Schrag","year":"2013","journal-title":"Vaccine"},{"key":"R9-8-20240319","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/j.1651-2227.1979.tb08218.x","article-title":"GROUP B streptococcal colonization OF pregnant women and their neonates epidemiological study and controlled trial of prophylactic treatment of the newborn","volume":"68","author":"Gerard","year":"1979","journal-title":"Acta P\u00e6diatrica"},{"key":"R10-8-20240319","doi-asserted-by":"crossref","first-page":"e8","DOI":"10.1542\/peds.2011-3453","article-title":"Long-term outcomes of group B streptococcal meningitis","volume":"130","author":"Libster","year":"2012","journal-title":"Pediatrics"}],"container-title":["International Journal of Pediatrics and Adolescent Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352646719300018?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2352646719300018?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijpam.2019.05.002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:27:57Z","timestamp":1786724877000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.1016\/j.ijpam.2019.05.002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.1016\/j.ijpam.2019.05.002","relation":{},"ISSN":["2352-6467"],"issn-type":[{"value":"2352-6467","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Incidence and outcome of group B streptococcal invasive disease in Omani infants","name":"articletitle","label":"Article Title"},{"value":"International Journal of Pediatrics and Adolescent Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpam.2019.05.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Publishing services provided by Elsevier B.V. on behalf of King Faisal Specialist Hospital & Research Centre (General Organization), Saudi Arabia.","name":"copyright","label":"Copyright"}]}}