{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T12:15:12Z","timestamp":1779279312305,"version":"3.51.4"},"reference-count":71,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal for Parasitology"],"published-print":{"date-parts":[[2006,5]]},"DOI":"10.1016\/j.ijpara.2006.01.013","type":"journal-article","created":{"date-parts":[[2006,3,7]],"date-time":"2006-03-07T12:09:30Z","timestamp":1141733370000},"page":"607-614","source":"Crossref","is-referenced-by-count":78,"title":["Microbial translocation of the blood\u2013brain barrier"],"prefix":"10.1016","volume":"36","author":[{"given":"Kwang Sik","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpara.2006.01.013_bib1","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1160\/TH05-01-0053","article-title":"Role of human brain microvascular endothelial cells during CNS infection: significance of indoleamine 2,3-dioxygenase in antimicrobial defense and immunoregulation","volume":"94","author":"Adam","year":"2005","journal-title":"Thrombo Haemost."},{"key":"10.1016\/j.ijpara.2006.01.013_bib2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.micpath.2003.07.001","article-title":"Acanthamoeba interactions with human brain microvascular endothelial cells","volume":"35","author":"Alsam","year":"2003","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.ijpara.2006.01.013_bib3","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1046\/j.1365-2958.2000.01840.x","article-title":"Identification of E. coli KI genes contributing to human brain microvascular endothelia cell invasion by differential fluorescence induction","volume":"36","author":"Badger","year":"2000","journal-title":"Mol. Micro."},{"key":"10.1016\/j.ijpara.2006.01.013_bib4","doi-asserted-by":"crossref","first-page":"5056","DOI":"10.1128\/IAI.68.9.5056-5061.2000","article-title":"Application of signature-tagged mutagenesis for the identification of E. coli K1 genes that contribute to invasion of the blood\u2013brain barrier","volume":"68","author":"Badger","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib5","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1542\/peds.76.6.901","article-title":"Routine quantitative blood cultures in children with Haemophilus influenzae or Streptococcus pneumoniae bacteremia","volume":"76","author":"Bell","year":"1985","journal-title":"Pediatrics"},{"key":"10.1016\/j.ijpara.2006.01.013_bib6","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1093\/emboj\/19.7.1458","article-title":"gC1q-R\/p32, a C1q-binding protein is a receptor for the In1B invasion protein of Listeria monocytogenes","volume":"19","author":"Braun","year":"2000","journal-title":"Eur. Mol. Biol. Org. J."},{"key":"10.1016\/j.ijpara.2006.01.013_bib7","doi-asserted-by":"crossref","first-page":"4985","DOI":"10.1128\/IAI.72.9.4985-4995.2004","article-title":"Cryptococcal yeast cells invade the central nervous system via transcellular penetration of the blood-brain barrier","volume":"72","author":"Chang","year":"2004","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib8","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0002-9440(10)62265-1","article-title":"Capsule structure changes associated with Cryptococcus neoformans crossing of the blood\u2013brain barrier","volume":"166","author":"Charlier","year":"2005","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib9","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1258\/095646204322637263","article-title":"Aetiology of meningitis in HIV-infected patients in a referral hospital in Phnom Penh, Cambodia","volume":"15","author":"Chin","year":"2004","journal-title":"Int. J. STD AIDS"},{"key":"10.1016\/j.ijpara.2006.01.013_bib10","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1086\/341564","article-title":"Pathogenesis of cerebral Cryptococcus neoformans infection after fungemia","volume":"4","author":"Chretien","year":"2002","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2006.01.013_bib11","doi-asserted-by":"crossref","first-page":"16857","DOI":"10.1074\/jbc.M301028200","article-title":"37kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake","volume":"278","author":"Chung","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijpara.2006.01.013_bib71","doi-asserted-by":"crossref","unstructured":"Conatamin, S., Galmiche, A., Doye, A., Flatau, G., Benmerah, A., Boquet, P., 2000. The p21 Rho-activating toxin cytotoxic necrotizing factor 1 is endocytosed by a clathrin-independent mechanism and enters the cytosol by an acidic-dependent membrane translocation. Mol. Biol. Cell. 11, 1775\u20131787.","DOI":"10.1091\/mbc.11.5.1775"},{"key":"10.1016\/j.ijpara.2006.01.013_bib12","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1126\/science.1090124","article-title":"Bacterial invasion: the paradigms of enteroinvasive pathogens","volume":"304","author":"Cossart","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.ijpara.2006.01.013_bib13","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1086\/322986","article-title":"Differential role of cytosolic phospholipase A2 in the invasion of brain microvascular endothelial cells by Escherichia coli and Listeria monocytogenes","volume":"184","author":"Das","year":"2001","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2006.01.013_bib14","doi-asserted-by":"crossref","first-page":"6527","DOI":"10.1128\/IAI.69.10.6527-6531.2001","article-title":"Restriction of toxoplasma gondii growth in human brain microvascular endothelial cells by activation of indolamine 2, 3-dioxygenase","volume":"69","author":"Daubener","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib15","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/S0022-3476(74)80308-2","article-title":"Neonatal Escherichia coli septicemia\u2014bacterial counts in blood","volume":"85","author":"Dietzman","year":"1974","journal-title":"J. Pediatr."},{"key":"10.1016\/j.ijpara.2006.01.013_bib16","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1128\/CMR.17.2.323-347.2004","article-title":"Invasion of the central nervous system by intracellular bacteria","volume":"17","author":"Drevets","year":"2004","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.ijpara.2006.01.013_bib17","series-title":"Principles and Practice of Infectious Disease","first-page":"2289","article-title":"Candida species","author":"Edwards","year":"1995"},{"key":"10.1016\/j.ijpara.2006.01.013_bib18","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1128\/IAI.27.3.1023-1032.1980","article-title":"Production of bacteremia and meningitis in infant rats with group B Streptococcal serotypes","volume":"27","author":"Ferrieri","year":"1980","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib19","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1086\/313910","article-title":"Bacterial meningitis in Malawian adults: pneumococcal disease is common, severe, and seasonal","author":"Gordon","year":"2000","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.ijpara.2006.01.013_bib20","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1645\/GE-287R","article-title":"African trypanosome interactions with an in vitro model of the human blood\u2013brain barrier","volume":"90","author":"Grab","year":"2004","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib21","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1128\/IAI.73.2.1014-1022.2005","article-title":"Borrelia burgdorferi, host-derived proteases, and the blood\u2013brain barrier","volume":"73","author":"Grab","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib22","doi-asserted-by":"crossref","first-page":"5260","DOI":"10.1128\/IAI.66.11.5260-5267.1998","article-title":"Interaction of Listeria monocytogenes with human brain microvascular endothelial cells: InlB-dependent invasion, long-term intracellular growth and spread from macrophages to endothelial cells","volume":"66","author":"Greiffenberg","year":"1998","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib23","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1097\/00002030-200007070-00013","article-title":"Impact of HIV infection on meningitis in Harare, Zimbabwe: a prospective study of 406 predominantly adult patients","volume":"14","author":"Hakim","year":"2000","journal-title":"AIDS"},{"key":"10.1016\/j.ijpara.2006.01.013_bib24","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1016\/S0140-6736(00)03493-0","article-title":"Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection","volume":"356","author":"Hernandez-Pando","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.ijpara.2006.01.013_bib25","doi-asserted-by":"crossref","first-page":"5062","DOI":"10.1128\/IAI.68.9.5062-5067.2000","article-title":"E. coli K1 aslA contributed to invasion of brain microvascular endothelial cells in vitro and in vivo","volume":"68","author":"Hoffman","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib26","doi-asserted-by":"crossref","first-page":"4470","DOI":"10.1128\/IAI.63.11.4470-4475.1995","article-title":"E. coli invasion of brain microvascular endothelial cells in vitro and in vivo: molecular cloning and characterization of E. coli invasion gene ibe10","volume":"63","author":"Huang","year":"1995","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib27","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1086\/319290","article-title":"Further characterization of Escherichia coli brain endothelial cell invasion gene ibeA by deletion, complementation and protein expression","volume":"183","author":"Huang","year":"2001","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2006.01.013_bib28","unstructured":"Jain, S.K., Paul-Satyaseela, M., Lamichhane, G., Kim, K.S., Bishai, W.R., in press. Mycobacterium tuberculosis invasion and traversal across an in vitro human blood\u2013brain barrier as a pathogenic mechanism for CNS tuberculosis. J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2006.01.013_bib29","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1111\/j.1462-5822.2004.00444.x","article-title":"Listeria monocytogenes-infected bone marrow myeloid cells promote bacterial invasion of the central nervous system","volume":"7","author":"Join-Lambert","year":"2005","journal-title":"Cell Microbiol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib30","doi-asserted-by":"crossref","first-page":"4536","DOI":"10.1128\/IAI.69.7.4536-4544.2001","article-title":"Traversal of C. albicans across human blood\u2013brain barrier in vitro","volume":"69","author":"Jong","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib31","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1099\/jmm.0.05060-0","article-title":"Binding of Candida albicans enolase to human plasmin(ogen) results in enhanced invasion of brain microvascular endothelial cells","volume":"52","author":"Jong","year":"2003","journal-title":"J. Med. Microbiol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib32","doi-asserted-by":"crossref","first-page":"15607","DOI":"10.1074\/jbc.M112224200","article-title":"Cytotoxic necrotizing factor 1 contributes to Escherichia coli K1 invasion of the central nervous system","volume":"277","author":"Khan","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijpara.2006.01.013_bib33","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0882-4010(03)00090-1","article-title":"Outer membrane protein A and cytotoxic necrotizing factor-1 use diverse signaling mechanisms for Escherichia coli K1 invasion of human brain microvascular endothelial cells","volume":"35","author":"Khan","year":"2003","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.ijpara.2006.01.013_bib34","doi-asserted-by":"crossref","first-page":"5217","DOI":"10.1128\/IAI.69.9.5217-5222.2001","article-title":"E. coli translocation at the blood\u2013brain barrier","volume":"69","author":"Kim","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib35","doi-asserted-by":"crossref","first-page":"S220","DOI":"10.1086\/344284","article-title":"Strategy of E. coli for crossing the blood\u2013brain barrier","volume":"186","author":"Kim","year":"2002","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2006.01.013_bib36","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nrn1103","article-title":"Neurological diseases: pathogenesis of bacterial meningitis: from bacteremia to neuronal injury","volume":"4","author":"Kim","year":"2003","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.ijpara.2006.01.013_bib37","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1172\/JCI115965","article-title":"The K1 capsule is the critical determinant in the development of Escherichia coli meningitis in the rat","volume":"90","author":"Kim","year":"1992","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ijpara.2006.01.013_bib38","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1046\/j.1462-5822.2003.t01-1-00271.x","article-title":"The K1 capsule modulates trafficking of E. coli-containing vacuoles and enhances intracellular bacterial survival in human brain microvascular endothelial cells","volume":"5","author":"Kim","year":"2003","journal-title":"Cell Microbiol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib39","doi-asserted-by":"crossref","first-page":"C31","DOI":"10.1152\/ajpcell.00157.2003","article-title":"Protease-activated receptors of human brain microvascular endothelial cells: expression and differential Ca2+ signaling induced by thrombin and protease-activated receptor-1 activating peptide","volume":"286","author":"Kim","year":"2004","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib40","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.ijmm.2005.07.004","article-title":"Invasion processes of pathogenic Escherichia coli","volume":"295","author":"Kim","year":"2005","journal-title":"Int. J. Med. Microbial."},{"key":"10.1016\/j.ijpara.2006.01.013_bib41","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1074\/jbc.M410176200","article-title":"67-kDa Laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells","volume":"280","author":"Kim","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijpara.2006.01.013_bib42","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1038\/35085062","article-title":"Pathogenic trickery: deception of host cell processes","volume":"2","author":"Knodler","year":"2001","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib43","doi-asserted-by":"crossref","first-page":"7318","DOI":"10.1128\/IAI.69.12.7318-7325.2001","article-title":"Streptococcus pneumoniae causes experimental meningitis following intranasal and otitis media infections via a nonhematogenous route","volume":"69","author":"Marra","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib44","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1093\/infdis\/135.2.303","article-title":"Haemophilus influenzae meningitis in infant rats: role of bacteremia in pathogenesis of age-dependent inflammatory, responses in cerebrospinal fluid","volume":"135","author":"Moxon","year":"1977","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2006.01.013_bib45","doi-asserted-by":"crossref","first-page":"5775","DOI":"10.1128\/IAI.67.11.5775-5783.1999","article-title":"Outer membrane A promoted cytoskeletal rearrangement of brain microvascular endothelial cells is required for E. coli invasion","volume":"67","author":"Nemani","year":"1999","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib46","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1128\/IAI.67.3.1131-1138.1999","article-title":"Identification and characterization of a novel Ibe10 binding protein contributing to E. coli invasion of brain microvascular endothelial cells","volume":"67","author":"Nemani","year":"1999","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib47","doi-asserted-by":"crossref","unstructured":"Nikolskaia, O.V., Kim, Y.V., Kovbasnjuk, O., Kim, K.J., Grab, D.J., this issue. Entry of Trypanosoma brucei gambiense into microvascular entothelial cells of the human blood\u2013brain barrier. Int. J. Parasitol. 36.","DOI":"10.1016\/j.ijpara.2006.01.011"},{"key":"10.1016\/j.ijpara.2006.01.013_bib48","doi-asserted-by":"crossref","first-page":"5074","DOI":"10.1128\/IAI.65.12.5074-5081.1997","article-title":"Invasion of brain microvascular endothelial cells by group B Streptococci","volume":"65","author":"Nizet","year":"1997","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib49","doi-asserted-by":"crossref","first-page":"7768","DOI":"10.1128\/JVI.79.12.7768-7776.2005","article-title":"Indoleamine 2, 3-dioxygenase (IDO) mediates cell type specific anti-measles virus activity of interferon-\u03b3","volume":"79","author":"Obojes","year":"2005","journal-title":"J. Virol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib50","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1016\/S0002-9440(10)63734-0","article-title":"Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion","volume":"164","author":"Olszewski","year":"2004","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib51","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0891-5520(02)00036-3","article-title":"Cryptococcus","volume":"4","author":"Perfect","year":"2002","journal-title":"Infect. Dis. Clin. North Am."},{"key":"10.1016\/j.ijpara.2006.01.013_bib52","doi-asserted-by":"crossref","first-page":"6423","DOI":"10.1128\/IAI.68.11.6423-6430.2000","article-title":"Involvement of focal adhesion kinases in Escherichia coli invasion of human brain microvascular endothelial cells","volume":"68","author":"Reddy","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib53","doi-asserted-by":"crossref","first-page":"36769","DOI":"10.1074\/jbc.M007382200","article-title":"Phosphatidylinositol 3-kinase activation and interaction with focal adhesion kinase in E coli K1 invasion of human brain microvascular endothelial cells","volume":"275","author":"Reddy","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijpara.2006.01.013_bib54","first-page":"5","article-title":"The pathogenesis of tuberculous meningitis","volume":"52","author":"Rich","year":"1933","journal-title":"Bull. Johns Hopkins Hosp."},{"key":"10.1016\/j.ijpara.2006.01.013_bib55","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1172\/JCI2406","article-title":"Pneumococcal trafficking across the blood\u2013brain barrier. Molecular analysis of a novel bi-directional pathway","volume":"102","author":"Ring","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ijpara.2006.01.013_bib56","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1146\/annurev.neuro.22.1.11","article-title":"The cell biology of the blood\u2013brain barrier","volume":"22","author":"Rubin","year":"1999","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.ijpara.2006.01.013_bib57","doi-asserted-by":"crossref","first-page":"5360","DOI":"10.1021\/bi035517c","article-title":"Cell-cell junctions of dermal microvascular endothelial cells contain tight and adherens junction proteins in spatial proximity","volume":"43","author":"Ruffer","year":"2004","journal-title":"Biochemistry"},{"key":"10.1016\/j.ijpara.2006.01.013_bib58","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0732-8893(00)00140-1","article-title":"The central nervous system and infection by Candida species","volume":"37","author":"Sanchez-Portocarrero","year":"2000","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.ijpara.2006.01.013_bib59","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0092-8674(00)00141-0","article-title":"InIB-dependent internalization of Listeria is mediated by the Met receptor tyrosine kinase","volume":"103","author":"Shen","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.ijpara.2006.01.013_bib60","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1111\/j.1462-5822.2004.00422.x","article-title":"Interaction of Neisseria meningitidis with human brain microvascular endothelial cells: role of MAP-and tyrosine kinases in invasion and inflammatory cytokine release","volume":"6","author":"Sokolova","year":"2004","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib61","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0165-5728(97)00036-2","article-title":"Selective expression of adhesion molecules on human brain microvascular endothelial cells","volume":"76","author":"Stins","year":"1997","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib62","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1006\/mpat.2000.0406","article-title":"Bacterial invasion and transcytosis in transfected human brain microvascular endothelial cells","volume":"30","author":"Stins","year":"2001","journal-title":"Microb. Pathog."},{"key":"10.1016\/j.ijpara.2006.01.013_bib63","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1542\/peds.69.6.699","article-title":"Relationship between the magnitude of bacteremia in children and the clinical disease","volume":"69","author":"Sullivan","year":"1982","journal-title":"Pediatrics"},{"key":"10.1016\/j.ijpara.2006.01.013_bib64","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.1128\/IAI.73.5.2923-2931.2005","article-title":"Escherichia coli K1 RS218 interacts with human brain microvascular endothelial cells via type 1 fimbria phase-on bacteria","volume":"73","author":"Teng","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib65","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1046\/j.1365-2958.2002.03222.x","article-title":"Fibronectin mediates Opc-dependent internalization of Neisseria meningitidis in human brain microvascular endothelial cells","volume":"46","author":"Unkmeir","year":"2002","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.ijpara.2006.01.013_bib66","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1203\/00006450-200205000-00003","article-title":"Role of OmpA and IbeB in Escherichia coli invasion of brain microvascular endothelial cells in vitro and in vivo","volume":"51","author":"Wang","year":"2002","journal-title":"Ped. Res."},{"key":"10.1016\/j.ijpara.2006.01.013_bib67","doi-asserted-by":"crossref","first-page":"4751","DOI":"10.1128\/IAI.67.9.4751-4756.1999","article-title":"The gene locus yijP contributes to E. coli K1 invasion of brain microvascular endothelial cells","volume":"67","author":"Wang","year":"1999","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib68","series-title":"World Health Report: Changing History","year":"2004"},{"key":"10.1016\/j.ijpara.2006.01.013_bib69","doi-asserted-by":"crossref","first-page":"2979","DOI":"10.1128\/IAI.68.5.2979-2984.2000","article-title":"Invasion of the brain and chronic central nervous system infection after systemic Mycobacterium avium complex infection in mice","volume":"68","author":"Wu","year":"2000","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2006.01.013_bib70","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.femsim.2004.09.001","article-title":"Current concepts on E. coli K1 translocation of the blood\u2013brain barrier","volume":"42","author":"Xie","year":"2004","journal-title":"FEMS Immunol. Med. Microbiol."}],"container-title":["International Journal for Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002075190600035X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002075190600035X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T17:47:15Z","timestamp":1683395235000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002075190600035X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5]]},"references-count":71,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["S002075190600035X"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpara.2006.01.013","relation":{},"ISSN":["0020-7519"],"issn-type":[{"value":"0020-7519","type":"print"}],"subject":[],"published":{"date-parts":[[2006,5]]}}}