{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T03:35:59Z","timestamp":1773027359779,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2008,4,1]],"date-time":"2008-04-01T00:00:00Z","timestamp":1207008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal for Parasitology"],"published-print":{"date-parts":[[2008,4]]},"DOI":"10.1016\/j.ijpara.2007.09.001","type":"journal-article","created":{"date-parts":[[2007,9,13]],"date-time":"2007-09-13T12:24:22Z","timestamp":1189686262000},"page":"493-502","source":"Crossref","is-referenced-by-count":61,"title":["CsCF-6, a novel cathepsin F-like cysteine protease for nutrient uptake of Clonorchis sinensis"],"prefix":"10.1016","volume":"38","author":[{"given":"Byoung-Kuk","family":"Na","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung-Mi","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woon-Mok","family":"Sohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpara.2007.09.001_bib1","doi-asserted-by":"crossref","first-page":"e14","DOI":"10.1371\/journal.pmed.0040014","article-title":"Schistosomiasis mansoni: novel chemotherapy using a cysteine protease inhibitor","volume":"4","author":"Abdulla","year":"2007","journal-title":"PLoS Med."},{"key":"10.1016\/j.ijpara.2007.09.001_bib2","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1128\/CMR.17.3.540-552.2004","article-title":"Clonorchiasis and cholangiocarcinoma: etiologic relationship and imaging diagnosis","volume":"17","author":"Choi","year":"2004","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.ijpara.2007.09.001_bib3","doi-asserted-by":"crossref","first-page":"5066","DOI":"10.1128\/IAI.64.12.5066-5074.1996","article-title":"Induction of protective immunity in cattle against infection with Fasciola hepatica by vaccination with cathepsin L proteinases and with hemoglobin","volume":"64","author":"Dalton","year":"1996","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2007.09.001_bib4","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1016\/S0020-7519(03)00171-1","article-title":"Fasciola hepatica cathepsin L-like proteases: biology, function, and potential in the development of first generation liver fluke vaccines","volume":"33","author":"Dalton","year":"2003","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2007.09.001_bib5","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0378-1119(00)00196-7","article-title":"Mouse cathepsin F: cDNA cloning, genomic organization and chromosomal assignment of the gene","volume":"251","author":"Deussing","year":"2000","journal-title":"Gene"},{"key":"10.1016\/j.ijpara.2007.09.001_bib6","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1017\/S0031182003004335","article-title":"A cathepsin F of adult Clonorchis sinensis and its phylogenetic conservation in trematodes","volume":"128","author":"Kang","year":"2004","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2007.09.001_bib7","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1016\/j.vaccine.2005.11.062","article-title":"Vaccination with DNA encoding cysteine proteinase confers protective immune response to rats infected with Clonorchis sinensis","volume":"24","author":"Lee","year":"2006","journal-title":"Vaccine"},{"key":"10.1016\/j.ijpara.2007.09.001_bib8","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1007\/s00436-004-1097-5","article-title":"The involvement of the cysteine proteases of Clonorchis sinensis metacercariae in excystment","volume":"93","author":"Li","year":"2004","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.ijpara.2007.09.001_bib9","doi-asserted-by":"crossref","first-page":"93","DOI":"10.4269\/ajtmh.2006.75.93","article-title":"Clonorchis sinensis infection and increasing risk of cholangiocarcinoma in the Republic of Korea","volume":"75","author":"Lim","year":"2006","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpara.2007.09.001_bib10","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1086\/386346","article-title":"Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms","volume":"189","author":"Loukas","year":"2004","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2007.09.001_bib11","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S1473-3099(04)01252-6","article-title":"Clonorchiasis: a key foodborne zoonosis in china","volume":"5","author":"Lun","year":"2005","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ijpara.2007.09.001_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.molbiopara.2004.02.010","article-title":"Molecular cloning and analysis of stage and tissue-specific expression of cathepsin B encoding genes from Fasciola gigantica","volume":"136","author":"Meemon","year":"2004","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2007.09.001_bib13","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1645\/0022-3395(2002)088[1000:EOCPOC]2.0.CO;2","article-title":"Expression of cysteine proteinase of Clonorchis sinensis and its use in serodiagnosis of clonorchiasis","volume":"88","author":"Na","year":"2002","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2007.09.001_bib14","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1042\/bj20031487","article-title":"Identification and biochemical characterization of vivapains, cysteine proteases of the malaria parasite Plasmodium vivax","volume":"378","author":"Na","year":"2004","journal-title":"Biochem. J."},{"key":"10.1016\/j.ijpara.2007.09.001_bib15","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1111\/j.1462-5822.2006.00685.x","article-title":"Critical roles for excretory-secretory cysteine proteases during tissue invasion of Paragonimus westermani newly excysted metacercariae","volume":"8","author":"Na","year":"2006","journal-title":"Cell Microbiol."},{"key":"10.1016\/j.ijpara.2007.09.001_bib16","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1128\/CDLI.11.2.411-416.2004","article-title":"Molecular expression of acysteine proteinase of Clonorchis sinensis and its application to an enzyme-linked immunosorbent assay for immunodiagnosis of clonorchiasis","volume":"11","author":"Nagano","year":"2004","journal-title":"Clin. Diagn. Lab. Immunol."},{"key":"10.1016\/j.ijpara.2007.09.001_bib17","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1006\/bbrc.1999.0461","article-title":"Full-length cDNA of human cathepsin F predicts the presence of a cystatin domain at the N-terminus of the cysteine protease zymogen","volume":"257","author":"N\u00e4gler","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ijpara.2007.09.001_bib18","doi-asserted-by":"crossref","first-page":"211","DOI":"10.3347\/kjp.1995.33.3.211","article-title":"Cytotoxicity of a cysteine proteinase of adult Clonorchis sinensis","volume":"33","author":"Park","year":"1995","journal-title":"Korean J. Parasitol."},{"key":"10.1016\/j.ijpara.2007.09.001_bib19","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1645\/0022-3395(2001)087[1454:CALSEO]2.0.CO;2","article-title":"Characterization and large-scale expression of the recombinant cysteine proteinase from adult Clonorchis sinensis","volume":"87","author":"Park","year":"2001","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2007.09.001_bib20","doi-asserted-by":"crossref","first-page":"1954","DOI":"10.1128\/IAI.67.4.1954-1961.1999","article-title":"Vaccination with cathepsin L proteinases and with leucine aminopeptidase induces high levels of protection against fascioliasis in sheep","volume":"67","author":"Piacenza","year":"1999","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2007.09.001_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0166-6851(01)00438-8","article-title":"Cysteine proteases of parasitic organisms","volume":"120","author":"Sajid","year":"2002","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2007.09.001_bib22","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/0305-0491(90)90129-H","article-title":"Clonorchis sinensis: purification and characterization of a cysteine proteinase from adult worms","volume":"97","author":"Song","year":"1990","journal-title":"Comp. Biochem. Physiol. B"},{"key":"10.1016\/j.ijpara.2007.09.001_bib23","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0305-0491(91)90018-9","article-title":"Cysteine proteinase activity in various developmental stages of Clonorchis sinensis: a comparative analysis","volume":"99","author":"Song","year":"1991","journal-title":"Comp. Biochem. Physiol. B"},{"key":"10.1016\/j.ijpara.2007.09.001_bib24","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0065-308X(08)60243-2","article-title":"Helminth proteinases and their associated genes","volume":"43","author":"Tort","year":"1999","journal-title":"Adv. Parasitol."}],"container-title":["International Journal for Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751907002998?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751907002998?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,26]],"date-time":"2020-04-26T13:38:22Z","timestamp":1587908302000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020751907002998"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,4]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["S0020751907002998"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpara.2007.09.001","relation":{},"ISSN":["0020-7519"],"issn-type":[{"value":"0020-7519","type":"print"}],"subject":[],"published":{"date-parts":[[2008,4]]}}}