{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T22:12:38Z","timestamp":1791843158898,"version":"4.3.4"},"reference-count":36,"publisher":"Elsevier BV","issue":"8-9","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal for Parasitology"],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1016\/j.ijpara.2007.11.005","type":"journal-article","created":{"date-parts":[[2007,11,27]],"date-time":"2007-11-27T14:20:11Z","timestamp":1196173211000},"page":"1051-1055","source":"Crossref","is-referenced-by-count":43,"title":["Fecundity of Cryptosporidium parvum is correlated with intracellular levels of the viral symbiont CPV"],"prefix":"10.1016","volume":"38","author":[{"given":"M.C.","family":"Jenkins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Higgins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.E.","family":"Abrahante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.E.","family":"Kniel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"O\u2019Brien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Trout","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.A.","family":"Lancto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.S.","family":"Abrahamsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Fayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpara.2007.11.005_bib1","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/S0040816602000757","article-title":"Visualization of new virus-like particles in Trichomonas vaginalis","volume":"34","author":"Benchimol","year":"2002","journal-title":"Tissue Cell"},{"key":"10.1016\/j.ijpara.2007.11.005_bib2","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1111\/j.1574-6968.2002.tb11391.x","article-title":"Trichomonas vaginalis: observation of coexistence of multiple viruses in the same isolate","volume":"15","author":"Benchimol","year":"2002","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.ijpara.2007.11.005_bib3","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S1383-5769(02)00016-8","article-title":"Virus in Trichomonas -- an ultrastructural study","volume":"51","author":"Benchimol","year":"2002","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.ijpara.2007.11.005_bib4","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1006\/viro.1999.0129","article-title":"The complete cDNA sequence of a type II Trichomonas vaginalis virus","volume":"267","author":"Bessarab","year":"2000","journal-title":"Virology"},{"key":"10.1016\/j.ijpara.2007.11.005_bib5","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S1016-8478(23)13392-9","article-title":"Generation of the short RNA transcript in Leishmaniavirus correlates with the growth of its parasite host, Leishmania","volume":"8","author":"Chung","year":"1998","journal-title":"Mol. Cell"},{"key":"10.1016\/j.ijpara.2007.11.005_bib6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/0166-6851(87)90190-3","article-title":"Occurrence and transfection of a Giardia virus","volume":"23","author":"De Jonckheere","year":"1987","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib7","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1016\/S0020-7519(01)00241-7","article-title":"Eimeria necatrix virus: intracellular localisation of viral particles and proteins","volume":"31","author":"del Cacho","year":"2001","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib8","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1006\/meth.2001.1261","article-title":"An overview of quantitative PCR: applications to quantify cytokine gene expression","volume":"25","author":"Giulietti","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.ijpara.2007.11.005_bib9","doi-asserted-by":"crossref","first-page":"182","DOI":"10.2307\/3284557","article-title":"Development and application of an improved semi-quantitative technique for detecting low level Cryptosporidium parvum infections in mouse tissue using polymerase chain reaction","volume":"84","author":"Jenkins","year":"1998","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib10","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0167-7012(00)00198-6","article-title":"Estimating viability of Cryptosporidium parvum oocysts using reverse transcriptase-polymerase chain reaction (RT-PCR) directed at mRNA encoding amyloglucosidase","volume":"43","author":"Jenkins","year":"2000","journal-title":"J. Microbiol. Methods"},{"key":"10.1016\/j.ijpara.2007.11.005_bib11","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0166-6851(91)90037-7","article-title":"A putative RNA virus in Babesia bovis","volume":"45","author":"Johnston","year":"1991","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib12","doi-asserted-by":"crossref","first-page":"7108","DOI":"10.1128\/JVI.68.11.7108-7114.1994","article-title":"Unique double-stranded RNAs associated with the Trichomonas vaginalis virus are synthesized by viral RNA-dependent RNA polymerase","volume":"68","author":"Khoshnan","year":"1994","journal-title":"J. Virol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib13","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1046\/j.1365-2958.1997.5721933.x","article-title":"Virus-like, double-stranded RNAs in the parasitic protozoan Cryptosporidium parvum","volume":"26","author":"Khramtsov","year":"1997","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib14","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1645\/0022-3395(2000)086[0275:PODSRI]2.0.CO;2","article-title":"Presence of double-stranded RNAs in human and calf isolates of Cryptosporidium parvum","volume":"86","author":"Khramtsov","year":"2000","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib15","doi-asserted-by":"crossref","first-page":"505","DOI":"10.4269\/ajtmh.1987.36.505","article-title":"Purification of Cryptosporidium oocysts and sporozoites by cesium chloride and Percoll gradients","volume":"36","author":"Kilani","year":"1987","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpara.2007.11.005_bib16","doi-asserted-by":"crossref","first-page":"208","DOI":"10.2307\/3285621","article-title":"RNA-dependent RNA polymerase activity associated with Eimeria necatrix virus particles containing either double-stranded or single-stranded RNA","volume":"85","author":"Lee","year":"1999","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib17","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0166-6851(88)90003-5","article-title":"Purification and characterization of the Giardia lamblia double-stranded RNA virus","volume":"28","author":"Miller","year":"1988","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib18","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/0014-4894(88)90056-2","article-title":"Identification of Giardia lamblia isolates susceptible and resistant to infection by the double-stranded RNA virus","volume":"66","author":"Miller","year":"1988","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib19","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1645\/GE-1020R.1","article-title":"A rapid method for producing highly purified Cryptosporidium parvum oocysts","volume":"93","author":"O\u2019Brien","year":"2007","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib20","first-page":"517","article-title":"Cryptosporidium virulence determinants \u2013 are we there yet? Int","volume":"32","author":"Okhuysen","year":"2002","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib21","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1086\/315033","article-title":"Virulence of three distinct Cryptosporidium parvum isolates for healthy adults","volume":"180","author":"Okhuysen","year":"1999","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2007.11.005_bib22","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/0166-6851(89)90168-0","article-title":"Identification of virus-like particles in Eimeria stiedae","volume":"36","author":"Revets","year":"1989","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib23","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1006\/viro.1996.0446","article-title":"Genomic organization and sequence conservation in type I Trichomonas vaginalis viruses","volume":"222","author":"Su","year":"1996","journal-title":"Virology"},{"key":"10.1016\/j.ijpara.2007.11.005_bib24","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1006\/expr.1993.1033","article-title":"The divergence of Trichomonas vaginalis virus RNAs among various isolates of Trichomonas vaginalis","volume":"76","author":"Tai","year":"1993","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib25","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1006\/viro.1996.0039","article-title":"Separation and characterization of two related giardiaviruses in the parasitic protozoan Giardia lamblia","volume":"216","author":"Tai","year":"1996","journal-title":"Virology"},{"key":"10.1016\/j.ijpara.2007.11.005_bib26","doi-asserted-by":"crossref","first-page":"9572","DOI":"10.1073\/pnas.85.24.9572","article-title":"LR1: a candidate RNA virus of Leishmania","volume":"85","author":"Tarr","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ijpara.2007.11.005_bib27","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/0272-4332.00014","article-title":"Cryptosporidium dose response studies: variation between isolates","volume":"22","author":"Teunis","year":"2002","journal-title":"Risk Anal."},{"key":"10.1016\/j.ijpara.2007.11.005_bib28","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0166-6851(86)90132-5","article-title":"Discovery of a specific double-stranded RNA virus in Giardia lamblia","volume":"21","author":"Wang","year":"1986","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib29","doi-asserted-by":"crossref","first-page":"7956","DOI":"10.1073\/pnas.83.20.7956","article-title":"The double-stranded RNA in Trichomonas vaginalis may originate from virus-like particles","volume":"83","author":"Wang","year":"1986","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ijpara.2007.11.005_bib30","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/0169-4758(91)90198-W","article-title":"Viruses of parasitic protozoa","volume":"7","author":"Wang","year":"1991","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.ijpara.2007.11.005_bib31","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1084\/jem.166.1.142","article-title":"Trichomonas vaginalis phenotypic variation occurs only among trichomonads infected with the double-stranded RNA virus","volume":"166","author":"Wang","year":"1987","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ijpara.2007.11.005_bib32","doi-asserted-by":"crossref","first-page":"8595","DOI":"10.1073\/pnas.90.18.8595","article-title":"Giardiavirus double-stranded RNA genome encodes a capsid polypeptide and a gag-pol-like fusion protein by a translation frameshift","volume":"90","author":"Wang","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ijpara.2007.11.005_bib33","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1136\/jcp.56.7.542","article-title":"Double stranded RNA virus in South African Trichomonas vaginalis isolates","volume":"56","author":"Weber","year":"2003","journal-title":"J. Clin. Pathol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib34","doi-asserted-by":"crossref","first-page":"3712","DOI":"10.1128\/JVI.64.8.3712-3715.1990","article-title":"RNA polymerase activity is associated with viral particles isolated from Leishmania braziliensis subsp. guyanensis","volume":"64","author":"Widmer","year":"1990","journal-title":"J. Virol."},{"key":"10.1016\/j.ijpara.2007.11.005_bib35","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3201\/eid0701.010121","article-title":"Tracking Cryptosporidium parvum by sequence analysis of small double-stranded RNA","volume":"7","author":"Xiao","year":"2001","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ijpara.2007.11.005_bib36","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1080\/00034980057464","article-title":"Phylogenetic analysis of the 5\u2032 subterminal region of isolates of Leishmania RNA virus-1","volume":"94","author":"Zamora","year":"2000","journal-title":"Ann. Trop. Med. Parasitol."}],"container-title":["International Journal for Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751907003967?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751907003967?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T19:14:43Z","timestamp":1708370083000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020751907003967"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":36,"journal-issue":{"issue":"8-9","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["S0020751907003967"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpara.2007.11.005","relation":{},"ISSN":["0020-7519"],"issn-type":[{"value":"0020-7519","type":"print"}],"subject":[],"published":{"date-parts":[[2008,7]]}}}