{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T10:30:57Z","timestamp":1758191457613,"version":"3.44.0"},"reference-count":109,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001825","name":"Danish Agency for Science and Higher Education","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001825","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000268","name":"Biotechnology and Biological Sciences Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001734","name":"K\u00f8benhavns Universitet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001734","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal for Parasitology"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.ijpara.2012.02.010","type":"journal-article","created":{"date-parts":[[2012,3,20]],"date-time":"2012-03-20T17:31:27Z","timestamp":1332264687000},"page":"383-391","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Detection of a quantitative trait locus associated with resistance to Ascaris suum infection in pigs"],"prefix":"10.1016","volume":"42","author":[{"given":"Per","family":"Skallerup","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Nejsum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claus B.","family":"J\u00f8rgensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harald H.H.","family":"G\u00f6ring","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Karlskov-Mortensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan L.","family":"Archibald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merete","family":"Fredholm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stig M.","family":"Thamsborg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpara.2012.02.010_b0005","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.1365-2249.2009.03948.x","article-title":"Association between total immunoglobulin E and antibody responses to naturally acquired Ascaris lumbricoides infection and polymorphisms of immune system-related LIG4, TNFSF13B and IRS2 genes","volume":"157","author":"Acevedo","year":"2009","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0010","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1186\/1471-2148-8-226","article-title":"Identification and characterization of novel human tissue-specific RFX transcription factors","volume":"8","author":"Aftab","year":"2008","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0015","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1086\/301844","article-title":"Multipoint quantitative-trait linkage analysis in general pedigrees","volume":"62","author":"Almasy","year":"1998","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ijpara.2012.02.010_b0020","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1016\/0035-9203(85)90128-2","article-title":"Hookworm burdens and faecal egg counts: an analysis of the biological basis of variation","volume":"79","author":"Anderson","year":"1985","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpara.2012.02.010_b0025","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1186\/1471-2164-11-438","article-title":"Pig genome sequence \u2013 analysis and publication strategy","volume":"11","author":"Archibald","year":"2010","journal-title":"BMC Genomics"},{"key":"10.1016\/j.ijpara.2012.02.010_b0030","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1084\/jem.190.7.953","article-title":"Tumor necrosis factor alpha is a critical component of interleukin 13-mediated protective T helper cell type 2 responses during helminth infection","volume":"190","author":"Artis","year":"1999","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ijpara.2012.02.010_b0035","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/0035-9203(90)90037-F","article-title":"Implications of faecal egg count variation when using the kato-katz method to assess Schistosoma mansoni infections","volume":"84","author":"Barreto","year":"1990","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpara.2012.02.010_b0040","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1079\/JOH2003174","article-title":"Chasing the genes that control resistance to gastrointestinal nematodes","volume":"77","author":"Behnke","year":"2003","journal-title":"J. Helminthol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0045","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/S0140-6736(06)68653-4","article-title":"Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm","volume":"367","author":"Bethony","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.ijpara.2012.02.010_b0050","doi-asserted-by":"crossref","first-page":"336","DOI":"10.4269\/ajtmh.2002.67.336","article-title":"Additive host genetic factors influence fecal egg excretion rates during Schistosoma mansoni infection in a rural area in Brazil","volume":"67","author":"Bethony","year":"2002","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"Pt 4","key":"10.1016\/j.ijpara.2012.02.010_b0055","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1017\/S0031182099006526","article-title":"The use of a gamma-type function to assess the relationship between the number of adult Teladorsagia circumcincta and total egg output","volume":"121","author":"Bishop","year":"2000","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2012.02.010_b0060","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1128\/CMR.00048-08","article-title":"HLA and infectious diseases","volume":"22","author":"Blackwell","year":"2009","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.ijpara.2012.02.010_b0065","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.1086\/652784","article-title":"Changes in plasma cytokines after treatment of Ascaris lumbricoides infection in individuals with HIV-1 infection","volume":"201","author":"Blish","year":"2010","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2012.02.010_b0070","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1111\/j.1469-1809.1986.tb01037.x","article-title":"The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods","volume":"50","author":"Boerwinkle","year":"1986","journal-title":"Ann. Hum. Genet."},{"issue":"Suppl.","key":"10.1016\/j.ijpara.2012.02.010_b0075","doi-asserted-by":"crossref","first-page":"S97","DOI":"10.1017\/S003118200000648X","article-title":"Animal models of intestinal nematode infections of humans","volume":"121","author":"Boes","year":"2000","journal-title":"Parasitology"},{"issue":"Pt 6","key":"10.1016\/j.ijpara.2012.02.010_b0080","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1017\/S0031182098003382","article-title":"Distribution of Ascaris suum in experimentally and naturally infected pigs and comparison with Ascaris lumbricoides infections in humans","volume":"117","author":"Boes","year":"1998","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2012.02.010_b0085","first-page":"314","article-title":"Construction of a genetic linkage map in man using restriction fragment length polymorphisms","volume":"32","author":"Botstein","year":"1980","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ijpara.2012.02.010_b0090","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1017\/S0031182008004976","article-title":"Heritability of human hookworm infection in Papua New Guinea","volume":"135","author":"Breitling","year":"2008","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2012.02.010_b0095","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1098\/rstb.1988.0100","article-title":"Population ecology of intestinal helminth infections in human communities","volume":"321","author":"Bundy","year":"1988","journal-title":"Philos. Trans. R. Soc. Lond. B. Biol. Sci."},{"key":"10.1016\/j.ijpara.2012.02.010_b0100","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1017\/S0950268800061719","article-title":"Predisposition to Trichuris trichiura infection in humans","volume":"98","author":"Bundy","year":"1987","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.ijpara.2012.02.010_b0105","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1086\/315830","article-title":"Human infection with Ascaris lumbricoides is associated with a polarized cytokine response","volume":"182","author":"Cooper","year":"2000","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2012.02.010_b0110","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1186\/1471-2164-10-96","article-title":"Mapping QTL influencing gastrointestinal nematode burden in Dutch Holstein\u2013Friesian dairy cattle","volume":"10","author":"Coppieters","year":"2009","journal-title":"BMC Genomics"},{"key":"10.1016\/j.ijpara.2012.02.010_b0115","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1086\/605844","article-title":"Heritable factors play a major role in determining host responses to Wuchereria bancrofti infection in an isolated south pacific island population","volume":"200","author":"Cuenco","year":"2009","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2012.02.010_b0120","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1128\/IAI.73.2.1116-1128.2005","article-title":"Localized multigene expression patterns support an evolving Th1\/Th2-like paradigm in response to infections with Toxoplasma gondii and Ascaris suum","volume":"73","author":"Dawson","year":"2005","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2012.02.010_b0125","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.micinf.2010.09.012","article-title":"Ascaris and ascariasis","volume":"13","author":"Dold","year":"2011","journal-title":"Microbes Infect."},{"key":"10.1016\/j.ijpara.2012.02.010_b0130","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1017\/S003118201000020X","article-title":"Detection of quantitative trait loci for internal parasite resistance in sheep. I. Linkage analysis in a Romney x Merino sheep backcross population","volume":"137","author":"Dominik","year":"2010","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2012.02.010_b0135","doi-asserted-by":"crossref","first-page":"689","DOI":"10.2307\/3277198","article-title":"Morphogenesis and migration of Ascaris suum larvae developing to fourth stage in swine","volume":"55","author":"Douvres","year":"1969","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0140","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0304-4017(92)90017-4","article-title":"Resistance to Ascaris suum in parasite naive and naturally exposed growers, finishers and sows","volume":"41","author":"Eriksen","year":"1992","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0145","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/BF00931733","article-title":"Response to repeated inoculations with Ascaris suum eggs in pigs during the fattening period. I. Studies on worm population kinetics","volume":"78","author":"Eriksen","year":"1992","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.ijpara.2012.02.010_b0150","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1101\/gr.086660.108","article-title":"Genetic architecture of quantitative traits in mice, flies, and humans","volume":"19","author":"Flint","year":"2009","journal-title":"Genome Res."},{"key":"10.1016\/j.ijpara.2012.02.010_b0155","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1021\/bi6023868","article-title":"Characterization of the RFX complex and the RFX5(L66A) mutant: implications for the regulation of MHC class II gene expression","volume":"46","author":"Garvie","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.ijpara.2012.02.010_b0160","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1365-2052.2007.01634.x","article-title":"Mapping of quantitative trait loci controlling tick [Riphicephalus (Boophilus) microplus] resistance on bovine chromosomes 5, 7 and 14","volume":"38","author":"Gasparin","year":"2007","journal-title":"Anim. Genet."},{"key":"10.1016\/j.ijpara.2012.02.010_b0165","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0304-4017(01)00587-8","article-title":"Genetic differences of Ascaridia galli egg output in laying hens following a single dose infection","volume":"103","author":"Gauly","year":"2002","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0170","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.vetpar.2008.02.019","article-title":"Comparative experimental Haemonchus contortus infection of two sheep breeds native to the Canary Islands","volume":"153","author":"Gonzalez","year":"2008","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0175","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1297-9686-41-46","article-title":"Quantitative trait loci for resistance to trichostrongylid infection in Spanish Churra sheep","volume":"41","author":"Gutierrez-Gil","year":"2009","journal-title":"Genet. Sel. Evol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0180","doi-asserted-by":"crossref","first-page":"220","DOI":"10.2527\/jas1985.601220x","article-title":"Influence of an experimental infection of Ascaris suum on performance of pigs","volume":"60","author":"Hale","year":"1985","journal-title":"J. Anim. Sci."},{"issue":"Suppl. 1","key":"10.1016\/j.ijpara.2012.02.010_b0185","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1111\/j.1740-8709.2007.00127.x","article-title":"A review and meta-analysis of the impact of intestinal worms on child growth and nutrition","volume":"4","author":"Hall","year":"2008","journal-title":"Matern. Child. Nutr."},{"key":"10.1016\/j.ijpara.2012.02.010_b0190","doi-asserted-by":"crossref","first-page":"7443","DOI":"10.1073\/pnas.1232392100","article-title":"Mapping of quantitative trait loci controlling trypanotolerance in a cross of tolerant West African N\u2019Dama and susceptible East African Boran cattle","volume":"100","author":"Hanotte","year":"2003","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ijpara.2012.02.010_b0195","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0304-4017(99)00007-2","article-title":"Concurrent Ascaris suum and Oesophagostomum dentatum infections in pigs","volume":"82","author":"Helwigh","year":"1999","journal-title":"Vet. Parasitol."},{"issue":"Pt 2","key":"10.1016\/j.ijpara.2012.02.010_b0200","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1017\/S003118200005873X","article-title":"The epidemiology of Ascaris lumbricoides and other soil-transmitted helminths in primary school children from ile-ife, Nigeria","volume":"99","author":"Holland","year":"1989","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2012.02.010_b0205","doi-asserted-by":"crossref","first-page":"915","DOI":"10.2307\/3283330","article-title":"A possible genetic factor influencing protection from infection with Ascaris lumbricoides in Nigerian children","volume":"78","author":"Holland","year":"1992","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0210","doi-asserted-by":"crossref","first-page":"517","DOI":"10.2307\/3279335","article-title":"Differential responses of duroc, hampshire, and crossbred pigs to a superimposed experimental infection with the intestinal threadworm, Strongyloides ransomi","volume":"61","author":"Johnson","year":"1975","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0215","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.vetpar.2010.11.007","article-title":"Genetic resistance to natural helminth infections in two chicken layer lines","volume":"176","author":"Kaufmann","year":"2011","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0220","series-title":"Hookworm Disease: Current Status and New Directions","first-page":"177","article-title":"Predisposition to helminth infection","author":"Keymer","year":"1990"},{"key":"10.1016\/j.ijpara.2012.02.010_b0225","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1128\/IAI.69.2.838-844.2001","article-title":"Critical role for signal transducer and activator of transcription factor 6 in mediating intestinal muscle hypercontractility and worm expulsion in Trichinella spiralis-infected mice","volume":"69","author":"Khan","year":"2001","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ijpara.2012.02.010_b0230","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.vetpar.2011.04.029","article-title":"Meta-analysis of the effects of endoparasites on pig performance","volume":"181","author":"Kipper","year":"2011","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0235","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.prevetmed.2011.01.009","article-title":"Does meatiness of pigs depend on the level of gastro-intestinal parasites infection?","volume":"99","author":"Knecht","year":"2011","journal-title":"Prev. Vet. Med."},{"key":"10.1016\/j.ijpara.2012.02.010_b0240","doi-asserted-by":"crossref","first-page":"2714","DOI":"10.1016\/j.molimm.2009.05.016","article-title":"The roles of eotaxin and the STAT6 signalling pathway in eosinophil recruitment and host resistance to the nematodes Nippostrongylus brasiliensis and Heligmosomoides bakeri","volume":"46","author":"Knott","year":"2009","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0245","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.ijpara.2006.04.008","article-title":"A time course study of immunological responses in Trichuris suis infected pigs demonstrates induction of a local type 2 response associated with worm burden","volume":"36","author":"Kringel","year":"2006","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0250","series-title":"The Genetics of the Pig","first-page":"426","article-title":"Pig as a model for biomedical sciences","author":"Kuzmuk","year":"2011"},{"key":"10.1016\/j.ijpara.2012.02.010_b0255","doi-asserted-by":"crossref","first-page":"101848","DOI":"10.1155\/2011\/101848","article-title":"The influence of MHC and immunoglobulins A and E on host resistance to gastrointestinal nematodes in sheep","volume":"2011","author":"Lee","year":"2011","journal-title":"J. Parasitol. Res."},{"key":"10.1016\/j.ijpara.2012.02.010_b0260","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1017\/S0031182005008978","article-title":"The development of a mouse model to explore resistance and susceptibility to early Ascaris suum infection","volume":"132","author":"Lewis","year":"2006","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2012.02.010_b0265","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/sj.ejhg.5200243","article-title":"Full results of the genome-wide scan which localises a locus controlling the intensity of infection by Schistosoma mansoni on chromosome 5q31\u2013q33","volume":"7","author":"Marquet","year":"1999","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.ijpara.2012.02.010_b0270","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.vetpar.2009.09.037","article-title":"Genetic factors of sheep affecting gastrointestinal parasite infections in the Distrito Federal, Brazil","volume":"166","author":"McManus","year":"2009","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0275","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1093\/nar\/16.3.1215","article-title":"A simple salting out procedure for extracting DNA from human nucleated cells","volume":"16","author":"Miller","year":"1988","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ijpara.2012.02.010_b0280","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1126\/science.285.5425.260","article-title":"BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator","volume":"285","author":"Moore","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.ijpara.2012.02.010_b0285","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0304-4017(96)01128-4","article-title":"Resistance of four sheep breeds to natural and subsequent artificial Haemonchus contortus infection","volume":"69","author":"Mugambi","year":"1997","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0290","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1017\/S0031182008005349","article-title":"The dynamics of genetically marked Ascaris suum infections in pigs","volume":"136","author":"Nejsum","year":"2009","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2012.02.010_b0295","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/hdy.2008.131","article-title":"High heritability for Ascaris and Trichuris infection levels in pigs","volume":"102","author":"Nejsum","year":"2009","journal-title":"Heredity"},{"key":"10.1016\/j.ijpara.2012.02.010_b0300","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1645\/GE-1987.1","article-title":"Population dynamics of Ascaris suum in trickle-infected pigs","volume":"95","author":"Nejsum","year":"2009","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0305","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1007\/s11250-010-9732-x","article-title":"Prevalence of gastrointestinal nematodes in growing pigs in Kabale District in Uganda","volume":"43","author":"Nissen","year":"2011","journal-title":"Trop. Anim. Health Prod."},{"key":"10.1016\/j.ijpara.2012.02.010_b0310","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/j.bbrc.2008.05.073","article-title":"An RNA biding protein, Y14 interacts with and modulates STAT3 activation","volume":"372","author":"Ohbayashi","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ijpara.2012.02.010_b0315","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1186\/BF03547520","article-title":"Embryonation and infectivity of Ascaris suum eggs. A comparison of eggs collected from worm uteri with eggs isolated from pig faeces","volume":"31","author":"Oksanen","year":"1990","journal-title":"Acta Vet. Scand."},{"key":"10.1016\/j.ijpara.2012.02.010_b0320","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.immuni.2008.03.004","article-title":"The biological functions of T helper 17 cell effector cytokines in inflammation","volume":"28","author":"Ouyang","year":"2008","journal-title":"Immunity"},{"key":"10.1016\/j.ijpara.2012.02.010_b0325","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/sj.gene.6364030","article-title":"An asthma-associated genetic variant of STAT6 predicts low burden of Ascaris worm infestation","volume":"5","author":"Peisong","year":"2004","journal-title":"Genes Immun."},{"issue":"Pt 6","key":"10.1016\/j.ijpara.2012.02.010_b0330","first-page":"545","article-title":"Ascaris, people and pigs in a rural community of Jiangxi province, China","volume":"113","author":"Peng","year":"1996","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2012.02.010_b0335","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1017\/S0031182000079920","article-title":"Frequency distributions of parasites in a population of three-spined sticklebacks, Gasterosteus aculeatus L., with particular reference to the negative binomial distribution","volume":"63","author":"Pennycuick","year":"1971","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2012.02.010_b0340","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1053\/jcpa.2000.0455","article-title":"Immunohistochemical characterization of hepatic lesions associated with migrating larvae of Ascaris suum in pigs","volume":"124","author":"Perez","year":"2001","journal-title":"J. Comp. Pathol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0345","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.ijpara.2009.08.002","article-title":"Human helminth co-infection: no evidence of common genetic control of hookworm and Schistosoma mansoni infection intensity in a Brazilian community","volume":"40","author":"Pullan","year":"2010","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0350","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","article-title":"PLINK: a tool set for whole-genome association and population-based linkage analyses","volume":"81","author":"Purcell","year":"2007","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ijpara.2012.02.010_b0355","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1016\/S0020-7519(03)00175-9","article-title":"Genetics of susceptibility to human helminth infection","volume":"33","author":"Quinnell","year":"2003","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0360","doi-asserted-by":"crossref","first-page":"e6524","DOI":"10.1371\/journal.pone.0006524","article-title":"Design of a high density SNP genotyping assay in the pig using SNPs identified and characterized by next generation sequencing technology","volume":"4","author":"Ramos","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpara.2012.02.010_b0365","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1007\/s004390050947","article-title":"Association of polymorphisms in the beta2-adrenoreceptor gene with higher levels of parasitic infection","volume":"104","author":"Ramsay","year":"1999","journal-title":"Hum. Genet."},{"key":"10.1016\/j.ijpara.2012.02.010_b0370","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.ygeno.2007.01.011","article-title":"Mapping of quantitative trait loci affecting resistance\/susceptibility to Sarcocystis miescheriana in swine","volume":"89","author":"Reiner","year":"2007","journal-title":"Genomics"},{"key":"10.1016\/j.ijpara.2012.02.010_b0375","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1126\/science.273.5281.1516","article-title":"The future of genetic studies of complex human diseases","volume":"273","author":"Risch","year":"1996","journal-title":"Science"},{"key":"10.1016\/j.ijpara.2012.02.010_b0380","article-title":"The large roundworm of pigs, Ascaris lumbricoides L., 1758. Its life history in Queensland, economic importance and control. Animal Health Station, Yeerongpilly, Queensland, Australia","volume":"81","author":"Roberts","year":"1934","journal-title":"Bulletin"},{"key":"10.1016\/j.ijpara.2012.02.010_b0385","doi-asserted-by":"crossref","first-page":"e432","DOI":"10.1111\/j.1365-2567.2008.02995.x","article-title":"Major histocompatibility complex (MHC) class II but not MHC class I molecules are required for efficient control of Strongyloides venezuelensis infection in mice","volume":"128","author":"Rodrigues","year":"2009","journal-title":"Immunology"},{"issue":"Pt 4","key":"10.1016\/j.ijpara.2012.02.010_b0390","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1017\/S0031182097001480","article-title":"Experimental Ascaris suum infection in the pig: worm population kinetics following single inoculations with three doses of infective eggs","volume":"115","author":"Roepstorff","year":"1997","journal-title":"Parasitology"},{"unstructured":"Roepstorff, A., Nansen, P., 1998. Epidemiology, diagnosis and control of helminth parasites of swine. Food and Agriculture Organization (FAO), Rome.","key":"10.1016\/j.ijpara.2012.02.010_b0395"},{"key":"10.1016\/j.ijpara.2012.02.010_b0400","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0304-4017(97)00223-9","article-title":"Intestinal parasites in swine in the Nordic countries: prevalence and geographical distribution","volume":"76","author":"Roepstorff","year":"1998","journal-title":"Vet. Parasitol."},{"issue":"Suppl. 16","key":"10.1016\/j.ijpara.2012.02.010_b0405","first-page":"1","article-title":"Studies on the aetiology and pathogenesis of white spots in the liver of pigs","volume":"7","author":"Roneus","year":"1966","journal-title":"Acta Vet. Scand."},{"key":"10.1016\/j.ijpara.2012.02.010_b0410","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.vetpar.2009.10.022","article-title":"Evaluation of three Pakistani sheep breeds for their natural resistance to artificial infection of Haemonchus contortus","volume":"168","author":"Saddiqi","year":"2010","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0415","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1126\/science.4012307","article-title":"Predisposition to hookworm infection in humans","volume":"228","author":"Schad","year":"1985","journal-title":"Science"},{"key":"10.1016\/j.ijpara.2012.02.010_b0420","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.meegid.2010.03.012","article-title":"Functional associations of similar MHC alleles and shared parasite species in two sympatric lemurs","volume":"10","author":"Schwensow","year":"2010","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0425","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.vetpar.2009.03.052","article-title":"A Th2 type of immune response is associated with increased resistance to Haemonchus contortus in naturally infected Gulf Coast Native lambs","volume":"163","author":"Shakya","year":"2009","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0430","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1186\/BF03548483","article-title":"Use of an agar-gel technique for large scale application to recover Ascaris suum larvae from intestinal contents of pigs","volume":"38","author":"Slotved","year":"1997","journal-title":"Acta Vet. Scand."},{"key":"10.1016\/j.ijpara.2012.02.010_b0435","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.livsci.2011.10.009","article-title":"Preliminary association of microsatellite heterozygosity with footrot in domestic sheep","volume":"143","author":"Smith","year":"2012","journal-title":"Livestock Sci."},{"key":"10.1016\/j.ijpara.2012.02.010_b0440","first-page":"58","article-title":"The effect of experimental infections with ascarids on the growth of pigs","volume":"14","author":"Spindler","year":"1947","journal-title":"Proc. Helminthol. Soc. Wash."},{"key":"10.1016\/j.ijpara.2012.02.010_b0445","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1111\/j.1365-3024.2009.01105.x","article-title":"Genetic variation in resistance to mixed, predominantly Teladorsagia circumcincta nematode infections of sheep: from heritabilities to gene identification","volume":"31","author":"Stear","year":"2009","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0450","doi-asserted-by":"crossref","first-page":"5161","DOI":"10.1016\/j.vaccine.2009.05.075","article-title":"Ascaris suum infection negatively affects the response to a Mycoplasma hyopneumoniae vaccination and subsequent challenge infection in pigs","volume":"27","author":"Steenhard","year":"2009","journal-title":"Vaccine"},{"key":"10.1016\/j.ijpara.2012.02.010_b0455","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.immuni.2010.12.013","article-title":"The transcription factor STAT3 is required for T helper 2 cell development","volume":"34","author":"Stritesky","year":"2011","journal-title":"Immunity"},{"key":"10.1016\/j.ijpara.2012.02.010_b0460","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.cell.2008.03.026","article-title":"TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis","volume":"133","author":"Sun","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.ijpara.2012.02.010_b0465","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.imlet.2011.01.002","article-title":"The MHC, disease and selection","volume":"137","author":"Trowsdale","year":"2011","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.ijpara.2012.02.010_b0470","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/S0749-0720(15)31218-4","article-title":"The epidemiology and control of swine parasites. Immunity and vaccines","volume":"2","author":"Urban","year":"1986","journal-title":"Vet. Clin. North Am. Food Anim. Pract."},{"key":"10.1016\/j.ijpara.2012.02.010_b0475","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/0014-4894(88)90051-3","article-title":"Ascaris suum: development of intestinal immunity to infective second-stage larvae in swine","volume":"66","author":"Urban","year":"1988","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0480","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S1074-7613(00)80477-X","article-title":"IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis","volume":"8","author":"Urban","year":"1998","journal-title":"Immunity"},{"key":"10.1016\/j.ijpara.2012.02.010_b0485","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.vetpar.2008.10.042","article-title":"Strain difference in susceptibility to Trichinella spiralis infection between dark agouti and albino oxford rats","volume":"159","author":"Vasilev","year":"2009","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0490","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1017\/S0031182000047156","article-title":"Genetic control of immune responses to parasites: selection for responsiveness and non-responsiveness to Trichuris muris in random-bred mice","volume":"71","author":"Wakelin","year":"1975","journal-title":"Parasitology"},{"issue":"3","key":"10.1016\/j.ijpara.2012.02.010_b0495","first-page":"CD006419","article-title":"Deworming helminth co-infected individuals for delaying HIV disease progression","author":"Walson","year":"2009","journal-title":"Cochrane Database Syst. Rev."},{"key":"10.1016\/j.ijpara.2012.02.010_b0500","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1126\/science.280.5366.1077","article-title":"Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome","volume":"280","author":"Wang","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.ijpara.2012.02.010_b0505","first-page":"388","article-title":"Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction","volume":"44","author":"Weber","year":"1989","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.ijpara.2012.02.010_b0510","doi-asserted-by":"crossref","first-page":"921","DOI":"10.4269\/ajtmh.1999.60.921","article-title":"Genetic analysis of susceptibility to infection with Ascaris lumbricoides","volume":"60","author":"Williams-Blangero","year":"1999","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpara.2012.02.010_b0515","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/gepi.0187","article-title":"Genetic component to susceptibility to Trichuris trichiura: evidence from two Asian populations","volume":"22","author":"Williams-Blangero","year":"2002","journal-title":"Genet. Epidemiol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0520","doi-asserted-by":"crossref","first-page":"5533","DOI":"10.1073\/pnas.082115999","article-title":"Genes on chromosomes 1 and 13 have significant effects on Ascaris infection","volume":"99","author":"Williams-Blangero","year":"2002","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ijpara.2012.02.010_b0525","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1086\/524060","article-title":"Localization of multiple quantitative trait loci influencing susceptibility to infection with Ascaris lumbricoides","volume":"197","author":"Williams-Blangero","year":"2008","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2012.02.010_b0530","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1086\/533493","article-title":"Two quantitative trait loci influence whipworm (Trichuris trichiura) infection in a Nepalese population","volume":"197","author":"Williams-Blangero","year":"2008","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2012.02.010_b0535","doi-asserted-by":"crossref","first-page":"3055","DOI":"10.1167\/iovs.09-4652","article-title":"Association of POAG risk factors and the Thr377Met MYOC mutation in an isolated Greek population","volume":"51","author":"Wirtz","year":"2010","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.ijpara.2012.02.010_b0540","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/76889","article-title":"Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity","volume":"1","author":"Yan","year":"2000","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.ijpara.2012.02.010_b0545","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0304-4017(99)00226-5","article-title":"Heritability of gastrointestinal nematode faecal egg counts in West African village N\u2019Dama cattle and its relation to age","volume":"89","author":"Zinsstag","year":"2000","journal-title":"Vet. Parasitol."}],"container-title":["International Journal for Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751912000513?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751912000513?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T13:59:41Z","timestamp":1758117581000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020751912000513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":109,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S0020751912000513"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpara.2012.02.010","relation":{},"ISSN":["0020-7519"],"issn-type":[{"type":"print","value":"0020-7519"}],"subject":[],"published":{"date-parts":[[2012,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Detection of a quantitative trait locus associated with resistance to Ascaris suum infection in pigs","name":"articletitle","label":"Article Title"},{"value":"International Journal for Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpara.2012.02.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}