{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T19:27:25Z","timestamp":1790796445850,"version":"4.1.0"},"reference-count":59,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T00:00:00Z","timestamp":1430438400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"name":"INCT"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal for Parasitology"],"published-print":{"date-parts":[[2015,5]]},"DOI":"10.1016\/j.ijpara.2014.12.008","type":"journal-article","created":{"date-parts":[[2015,4,6]],"date-time":"2015-04-06T07:23:10Z","timestamp":1428304990000},"page":"385-391","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Revealing praziquantel molecular targets using mass spectrometry imaging: an expeditious approach applied to Schistosoma mansoni"],"prefix":"10.1016","volume":"45","author":[{"given":"M\u00f4nica Siqueira","family":"Ferreira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosimeire Nunes","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diogo Noin","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cibele Zanardi","family":"Esteves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silmara Marques","family":"Allegretti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo Ramos","family":"Catharino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpara.2014.12.008_b0005","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1046\/j.1365-3024.1996.d01-6.x","article-title":"The tegument of Schistosoma mansoni: functional and immunological features","volume":"18","author":"Abath","year":"1996","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0010","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/356604a0","article-title":"Tumour necrosis factor \u03b1 restores granulomas and induces parasite egg-laying in schistosome-infected SCID mice","author":"Amiri","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.ijpara.2014.12.008_b0015","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0163-7258(85)90020-8","article-title":"Praziquantel: mechanisms of anti-schistosomal activity","volume":"29","author":"Andrews","year":"1985","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.ijpara.2014.12.008_b0020","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1042\/bj3030341","article-title":"Evidence against involvement of the acid lysosomal sphingomyelinase in the tumor-necrosis-factor-and interleukin-1-induced sphingomyelin cycle and cell proliferation in human fibroblasts","volume":"303","author":"Andrieu","year":"1994","journal-title":"Biochem. J."},{"key":"10.1016\/j.ijpara.2014.12.008_b0025","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/BF00927527","article-title":"Light and electron microscopic studies on the effect of praziquantel on Schistosoma mansoni, Dicrocoelium dendriticum, and Fasciola hepatica (Trematoda) in vitro","volume":"63","author":"Becker","year":"1980","journal-title":"Z. Parasitenkd."},{"key":"10.1016\/j.ijpara.2014.12.008_b0030","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1002\/j.1460-2075.1995.tb07099.x","article-title":"Tumor necrosis factor (TNF)-alpha activates c-raf-1 kinase via the p55 TNF receptor engaging neutral sphingomyelinase","volume":"14","author":"Belka","year":"1995","journal-title":"EMBO J."},{"key":"10.1016\/j.ijpara.2014.12.008_b0035","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1139\/o59-099","article-title":"A rapid method of total lipid extraction and purification","volume":"37","author":"Bligh","year":"1959","journal-title":"Can. J. Biochem. Phys."},{"key":"10.1016\/j.ijpara.2014.12.008_b0040","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0166-6851(98)00103-0","article-title":"Ether lipids and their possible physiological function in adult Schistosoma mansoni","volume":"96","author":"Brouwers","year":"1998","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0045","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1038\/nmeth1094","article-title":"MALDI imaging mass spectrometry: molecular snapshots of biochemical systems","volume":"4","author":"Cornett","year":"2007","journal-title":"Nat. Methods"},{"key":"10.1016\/j.ijpara.2014.12.008_b0300","doi-asserted-by":"crossref","first-page":"PL289","DOI":"10.1016\/S0024-3205(97)00144-6","article-title":"Praziquantel has no direct effect on (Na+\/K+)-ATPases and (Ca2+\/Mg2+) ATPases of Schistosoma mansoni","volume":"60","author":"Cunha","year":"1997","journal-title":"Life Sci."},{"key":"10.1016\/j.ijpara.2014.12.008_b0055","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/0169-4758(92)90070-I","article-title":"Praziquantel: the enigmatic antiparasitic","volume":"8","author":"Day","year":"1992","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.ijpara.2014.12.008_b0060","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.3390\/ma6031000","article-title":"Cosmetic analysis using matrix-assisted laser desorption\/ionization mass spectrometry imaging (MALDI-MSI)","volume":"6","author":"de Oliveira","year":"2013","journal-title":"Materials"},{"key":"10.1016\/j.ijpara.2014.12.008_b0065","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1097\/QCO.0b013e328318978f","article-title":"Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis","volume":"21","author":"Doenhoff","year":"2008","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.ijpara.2014.12.008_b0070","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1111\/j.1432-1033.1991.tb15776.x","article-title":"Phosphatidylinositol-specific phospholipase C induces biosynthesis of acetylcholinesterase via diacylglycerol in Schistosoma mansoni","volume":"195","author":"Espinoza","year":"1991","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.ijpara.2014.12.008_b0075","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.pt.2003.09.005","article-title":"Drugs for the control of parasitic diseases: current status and development in schistosomiasis","volume":"19","author":"Fenwick","year":"2003","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0080","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.aca.2013.11.033","article-title":"Lipid characterization of embryo zones by silica plate laser desorption ionization mass spectrometry imaging (SP-LDI-MSI)","volume":"807","author":"Ferreira","year":"2014","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.ijpara.2014.12.008_b0085","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1002\/jms.3308","article-title":"Mass spectrometry imaging: a new vision in differentiating Schistosoma mansoni strains","volume":"49","author":"Ferreira","year":"2014","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.ijpara.2014.12.008_b0090","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1093\/glycob\/cws004","article-title":"Structural characterization of Schistosoma mansoni adult worm glycosphingolipids reveals pronounced differences with those of cercariae","volume":"22","author":"Frank","year":"2012","journal-title":"Glycobiology"},{"key":"10.1016\/j.ijpara.2014.12.008_b0305","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/0169-4758(91)90139-F","article-title":"Role of lipids in Schistosoma mansoni","volume":"7","author":"Fried","year":"1991","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.ijpara.2014.12.008_b0100","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0169-4758(91)90192-Q","article-title":"Unique roles for lipids in Schistosoma mansoni","volume":"7","author":"Furlong","year":"1991","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.ijpara.2014.12.008_b0105","doi-asserted-by":"crossref","first-page":"253","DOI":"10.2307\/3282452","article-title":"Schistosoma mansoni: correlations between mouse strain, skin eicosanoid production, and cercarial skin penetration","volume":"73","author":"Fusco","year":"1988","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0110","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1046\/j.1365-3024.1996.d01-66.x","article-title":"Is the induction of apoptosis the mechanism of the protective effects of TNF-\u03b1 in helminth infection?","volume":"18","author":"Garside","year":"1996","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0115","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1007\/BF00389899","article-title":"Praziquantel, a new broad-spectrum antischistosomal agent","volume":"52","author":"G\u00f6nnert","year":"1977","journal-title":"Z. Parasitenkd."},{"key":"10.1016\/j.ijpara.2014.12.008_b0120","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1111\/pim.1993.15.10.553","article-title":"Is tumour necrosis factor alpha the molecular basis of concomitant immunity in schistosomiasis?","volume":"15","author":"Hagan","year":"1993","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0125","doi-asserted-by":"crossref","first-page":"3125","DOI":"10.1016\/S0021-9258(17)41834-5","article-title":"The sphingomyelin cycle and the second messenger function of ceramide","volume":"269","author":"Hannun","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijpara.2014.12.008_b0130","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0166-6851(88)90119-3","article-title":"Influence of praziquantel and Ca2+ on the bilayer-isotropic-hexagonal transition of model membranes","volume":"29","author":"Harder","year":"1988","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0135","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0020-7519(73)90004-0","article-title":"Schistosoma mansoni: changes in the outer membrane of the tegument during development from cercaria to adult worm","volume":"3","author":"Hockley","year":"1973","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0140","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.molmed.2004.03.002","article-title":"Schistosome transcriptomes: new insights into the parasite and schistosomiasis","volume":"10","author":"Hu","year":"2004","journal-title":"Trends Mol. Med."},{"key":"10.1016\/j.ijpara.2014.12.008_b0145","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0092-8674(94)90147-3","article-title":"The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling","volume":"77","author":"Kolesnick","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.ijpara.2014.12.008_b0150","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1017\/S0031182000077763","article-title":"Effects of culture and praziquantel on membrane fluidity parameters of adult Schistosoma mansoni","volume":"109","author":"Lima","year":"1994","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2014.12.008_b0155","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.parint.2004.01.009","article-title":"Schistosoma mansoni genome project: an update","volume":"53","author":"LoVerde","year":"2004","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.ijpara.2014.12.008_b0160","doi-asserted-by":"crossref","first-page":"e54269","DOI":"10.1371\/journal.pone.0054269","article-title":"Irradiated riboflavin diminishes the aggressiveness of melanoma in vitro and in vivo","volume":"8","author":"Machado","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpara.2014.12.008_b0165","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0022-2275(20)38834-9","article-title":"Sphingomyelin and ceramide-phosphoethanolamine synthesis by microsomes and plasma membranes from rat liver and brain","volume":"27","author":"Malgat","year":"1986","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.ijpara.2014.12.008_b0170","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1017\/S0031182000085516","article-title":"Disguise as an evasive stratagem of parasitic organisms","volume":"88","author":"McLaren","year":"1984","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2014.12.008_b0175","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0378-4347(00)00397-2","article-title":"Capillary electrophoresis\u2013mass spectrometry, liquid chromatography\u2013mass spectrometry and nanoelectrospray-mass spectrometry of praziquantel metabolites","volume":"748","author":"Meier","year":"2000","journal-title":"J. Chrom. B Biomed. Sci. Appl."},{"key":"10.1016\/j.ijpara.2014.12.008_b0180","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0731-7085(01)00417-4","article-title":"Investigation of praziquantel metabolism in isolated rat hepatocytes","volume":"26","author":"Meier","year":"2001","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.ijpara.2014.12.008_b0185","doi-asserted-by":"crossref","first-page":"1769","DOI":"10.1126\/science.8456305","article-title":"Programmed cell death induced by ceramide","volume":"259","author":"Obeid","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.ijpara.2014.12.008_b0190","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2307\/3274166","article-title":"An efficient method for exposure of mice to cercariae of Schistosoma mansoni","volume":"38","author":"Olivier","year":"1952","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0195","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/BF00507974","article-title":"A benzodiazepine derivative and praziquantel: effects on musculature of Schistosoma mansoni and Schistosoma japonicum","volume":"304","author":"Pax","year":"1978","journal-title":"Naunyn Schmiedebergs Arch Pharmacol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0200","doi-asserted-by":"crossref","first-page":"201","DOI":"10.4269\/ajtmh.1962.11.201","article-title":"New approach to the screening of drugs in experimental schistosomiasis mansoni in mice","volume":"11","author":"Pellegrino","year":"1962","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpara.2014.12.008_b0205","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.ijpara.2003.12.003","article-title":"Sex-and stage-related sensitivity of Schistosoma mansoni to in vivo and in vitro praziquantel treatment","volume":"34","author":"Pica-Mattoccia","year":"2004","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0210","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.actatropica.2009.04.011","article-title":"Effect of praziquantel treatment on the expression of matrix metalloproteinases in relation to tissue resorption during fibrosis in hamsters with acute and chronic Opisthorchis viverrini infection","volume":"111","author":"Pinlaor","year":"2009","journal-title":"Acta Trop."},{"key":"10.1016\/j.ijpara.2014.12.008_b0215","doi-asserted-by":"crossref","first-page":"14572","DOI":"10.1016\/S0021-9258(18)82367-5","article-title":"Sphingomyelinase and ceramide activate mitogen-activated protein kinase in myeloid HL-60 cells","volume":"268","author":"Raines","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijpara.2014.12.008_b0220","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/0169-4758(96)80640-5","article-title":"Praziquantel: an urgent and exciting challenge","volume":"12","author":"Redman","year":"1996","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.ijpara.2014.12.008_b0225","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0166-6851(97)00151-5","article-title":"Interconversion of sphingomyelin and ceramide in adult Schistosoma mansoni","volume":"90","author":"Redman","year":"1997","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0230","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.aca.2014.01.050","article-title":"In situ assessment of atorvastatin impurity using MALDI mass spectrometry imaging (MALDI-MSI)","volume":"818","author":"Rodrigues","year":"2014","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.ijpara.2014.12.008_b0235","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/0014-4894(86)90184-0","article-title":"Schistosoma mansoni: chemotherapy of infections of different ages","volume":"61","author":"Sabah","year":"1986","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0240","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/0014-4894(77)90056-X","article-title":"Schistosoma mansoni. In vitro stimulation of vitelline cell development by extracts of male worms","volume":"42","author":"Shaw","year":"1977","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0245","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1017\/S0031182000082251","article-title":"Lipid fractions in adult Schistosoma mansoni","volume":"59","author":"Smith","year":"1969","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2014.12.008_b0250","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1517\/17460441.2.4.503","article-title":"Autoradiography: high-resolution molecular imaging in pharmaceutical discovery and development","volume":"2","author":"Solon","year":"2007","journal-title":"Expert Opin. Drug Discov."},{"key":"10.1016\/j.ijpara.2014.12.008_b0255","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/j.ijantimicag.2006.12.018","article-title":"Praziquantel binds Schistosoma mansoni adult worm actin","volume":"29","author":"Tallima","year":"2007","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.ijpara.2014.12.008_b0260","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/S0968-0004(96)10056-6","article-title":"Sphingomyelin breakdown and cell fate","volume":"21","author":"Testi","year":"1996","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.ijpara.2014.12.008_b0265","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.ijantimicag.2007.05.004","article-title":"Is actin the praziquantel receptor?","volume":"30","author":"Troiani","year":"2007","journal-title":"Int. J. Antimicrob. Agents"},{"key":"10.1016\/j.ijpara.2014.12.008_b0270","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1002\/rcm.4420","article-title":"Comprehensive mass spectrometry based metabolic profiling of blood plasma reveals potent discriminatory classifiers of pancreatic cancer","volume":"24","author":"Urayama","year":"2010","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.ijpara.2014.12.008_b0275","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1021\/pr050036w","article-title":"Mass spectrometric analysis of the Schistosoma mansoni tegumental sub-proteome","volume":"4","author":"van Balkom","year":"2005","journal-title":"J. Prot. Res."},{"key":"10.1016\/j.ijpara.2014.12.008_b0280","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/BF00389901","article-title":"A comparison of the susceptibility to praziquantel of Schistosoma haematobium, S. japonicum, S. mansoni, S. intercalatum and S. mattheei in hamsters","volume":"52","author":"Webbe","year":"1977","journal-title":"Z. Parasitenkd."},{"key":"10.1016\/j.ijpara.2014.12.008_b0285","doi-asserted-by":"crossref","first-page":"358","DOI":"10.4269\/ajtmh.1992.46.358","article-title":"Developmental expression of protein kinase C activity in Schistosoma mansoni","volume":"46","author":"Wiest","year":"1992","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpara.2014.12.008_b0290","doi-asserted-by":"crossref","first-page":"e1003254","DOI":"10.1371\/journal.ppat.1003254","article-title":"Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII","volume":"9","author":"You","year":"2013","journal-title":"PLoS Pathol."},{"key":"10.1016\/j.ijpara.2014.12.008_b0295","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/0166-6851(82)90018-4","article-title":"Major phospholipids and phosphatidylcholine synthesis in adult Schistosoma mansoni","volume":"5","author":"Young","year":"1982","journal-title":"Mol. Biochem. Parasitol."}],"container-title":["International Journal for Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751915000491?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751915000491?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T11:34:32Z","timestamp":1651664072000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020751915000491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5]]},"references-count":59,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,5]]}},"alternative-id":["S0020751915000491"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpara.2014.12.008","relation":{},"ISSN":["0020-7519"],"issn-type":[{"value":"0020-7519","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Revealing praziquantel molecular targets using mass spectrometry imaging: an expeditious approach applied to Schistosoma mansoni","name":"articletitle","label":"Article Title"},{"value":"International Journal for Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpara.2014.12.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}