{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T11:06:14Z","timestamp":1786791974697,"version":"build-2736575974"},"reference-count":61,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Victoria Life Sciences Computation Initiative","award":["VR0007"],"award-info":[{"award-number":["VR0007"]}]},{"DOI":"10.13039\/501100001782","name":"The University of Melbourne","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001782","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal for Parasitology"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.ijpara.2015.01.007","type":"journal-article","created":{"date-parts":[[2015,3,5]],"date-time":"2015-03-05T04:55:45Z","timestamp":1425531345000},"page":"333-343","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":119,"title":["Low cost whole-organism screening of compounds for anthelmintic activity"],"prefix":"10.1016","volume":"45","author":[{"given":"Sarah","family":"Preston","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul","family":"Jabbar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron","family":"Nowell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anja","family":"Joachim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e4rbel","family":"Ruttkowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Baell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Cardno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasi K.","family":"Korhonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Piedrafita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan R.E.","family":"Ansell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron R.","family":"Jex","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Hofmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin B.","family":"Gasser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpara.2015.01.007_b0005","doi-asserted-by":"crossref","first-page":"4428","DOI":"10.1016\/j.bmcl.2008.06.048","article-title":"Biphenyl amide p38 kinase inhibitors 3: improvement of cellular and in vivo activity","volume":"18","author":"Angell","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ijpara.2015.01.007_b0010","doi-asserted-by":"crossref","first-page":"4433","DOI":"10.1016\/j.bmcl.2008.06.028","article-title":"Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes","volume":"18","author":"Angell","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ijpara.2015.01.007_b0015","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.bmcl.2007.10.043","article-title":"Biphenyl amide p38 kinase inhibitors 2: optimisation and SAR","volume":"18","author":"Angell","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ijpara.2015.01.007_b0020","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.bmcl.2007.10.076","article-title":"Biphenyl amide p38 kinase inhibitors 1: discovery and binding mode","volume":"18","author":"Angell","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ijpara.2015.01.007_b0025","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1006\/mcbr.2001.0300","article-title":"Isolation and characterization of pmk-(1\u20133): three p38 homologs in Caenorhabditis elegans","volume":"4","author":"Berman","year":"2001","journal-title":"Mol. Cell. Biol. Res. Commun."},{"key":"10.1016\/j.ijpara.2015.01.007_b0030","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.pt.2006.11.004","article-title":"New anthelmintics for livestock: the time is right","volume":"23","author":"Besier","year":"2007","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0035","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.exppara.2011.02.016","article-title":"Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication","volume":"128","author":"Brumlik","year":"2011","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0040","first-page":"226","article-title":"Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: applications in the search for new anthelmintics","volume":"4","author":"Buckingham","year":"2014","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0045","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1126\/science.6308762","article-title":"Ivermectin: a potent new anthelmintic agent","volume":"221","author":"Campbell","year":"1983","journal-title":"Science"},{"key":"10.1016\/j.ijpara.2015.01.007_b0050","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.biotechadv.2011.08.016","article-title":"Key strongylid nematodes of animals \u2013 impact of next-generation transcriptomics on systems biology and biotechnology","volume":"30","author":"Cantacessi","year":"2012","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.ijpara.2015.01.007_b0055","doi-asserted-by":"crossref","first-page":"5428","DOI":"10.1016\/j.bmcl.2008.09.040","article-title":"The identification of pyrazolo[1,5-\u03b1]pyridines as potent p38 kinase inhibitors","volume":"18","author":"Cheung","year":"2008","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ijpara.2015.01.007_b0060","doi-asserted-by":"crossref","first-page":"e804","DOI":"10.1371\/journal.pntd.0000804","article-title":"Identification of attractive drug targets in neglected-disease pathogens using an in silico approach","volume":"4","author":"Crowther","year":"2010","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.ijpara.2015.01.007_b0065","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1042\/BJ20100323","article-title":"Mechanisms and functions of p38 MAPK signalling","volume":"429","author":"Cuadrado","year":"2010","journal-title":"Biochem. J."},{"key":"10.1016\/j.ijpara.2015.01.007_b0070","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.vetpar.2010.08.020","article-title":"Standardization of the larval migration inhibition test for the detection of resistance to ivermectin in gastro intestinal nematodes of ruminants","volume":"174","author":"Demeler","year":"2010","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0075","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0304-4017(86)90034-8","article-title":"An egg-hatch assay for resistance to levamisole in trichostrongyloid nematode parasites","volume":"19","author":"Dobson","year":"1986","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0080","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1186\/1471-2164-11-222","article-title":"Drug target prediction and prioritization: using orthology to predict essentiality in parasite genomes","volume":"11","author":"Doyle","year":"2010","journal-title":"BMC Genomics"},{"key":"10.1016\/j.ijpara.2015.01.007_b0085","doi-asserted-by":"crossref","first-page":"e60618","DOI":"10.1371\/journal.pone.0060618","article-title":"Drug target prediction and repositioning using an integrated network-based approach","volume":"8","author":"Emig","year":"2013","journal-title":"PLoS ONE"},{"issue":"12","key":"10.1016\/j.ijpara.2015.01.007_b0090","first-page":"9","article-title":"New advancement in anthelmintic drugs in veterinary medicine","volume":"29","author":"Epe","year":"2013","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0095","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.pt.2012.02.006","article-title":"A new approach for anthelmintic discovery for humans","volume":"28","author":"Geary","year":"2012","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0100","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1016\/j.bcp.2008.08.020","article-title":"Characterization and inhibition of a p38-like mitogen-activated protein kinase (MAPK) from Echinococcus multilocularis: antiparasitic activities of p38 MAPK inhibitors","volume":"76","author":"Gelmedin","year":"2008","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0105","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1039\/C3MD00255A","article-title":"Discovery of acrylonitrile-based small molecules active against Haemonchus contortus","volume":"5","author":"Gordon","year":"2014","journal-title":"Med. Chem. Commun."},{"key":"10.1016\/j.ijpara.2015.01.007_b0110","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1007\/s004360100479","article-title":"Activity of the cyclic depsipeptide emodepside (BAY 44\u20134400) against larval and adult stages of nematodes in rodents and the influence on worm survival","volume":"87","author":"Harder","year":"2001","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.ijpara.2015.01.007_b0115","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1016\/j.lfs.2006.08.010","article-title":"Anthelmintic resistance: the state of play revisited","volume":"79","author":"Jabbar","year":"2006","journal-title":"Life Sci."},{"key":"10.1016\/j.ijpara.2015.01.007_b0120","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/nature10553","article-title":"Ascaris suum draft genome","volume":"479","author":"Jex","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.ijpara.2015.01.007_b0125","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/ng.3012","article-title":"Genome and transcriptome of the porcine whipworm Trichuris suis","volume":"46","author":"Jex","year":"2014","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ijpara.2015.01.007_b0130","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1007\/s00436-008-1080-7","article-title":"Identification of the amino-acetonitrile derivative monepantel (AAD 1566) as a new anthelmintic drug development candidate","volume":"103","author":"Kaminsky","year":"2008","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.ijpara.2015.01.007_b0135","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.pt.2004.08.001","article-title":"Drug resistance in nematodes of veterinary importance: a status report","volume":"20","author":"Kaplan","year":"2004","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0140","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.vetpar.2011.11.048","article-title":"An inconvenient truth: global worming and anthelmintic resistance","volume":"186","author":"Kaplan","year":"2012","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0145","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.vetpar.2006.01.017","article-title":"A modified larval migration assay for detection of resistance to macrocyclic lactones in Haemonchus contortus, and drug screening with Trichostrongylidae parasites","volume":"137","author":"Kotze","year":"2006","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0150","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1186\/gb-2013-14-8-r88","article-title":"The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery","volume":"14","author":"Laing","year":"2013","journal-title":"Genome Biol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0155","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0304-4017(76)90067-4","article-title":"Egg hatch as an in vitro assay of thiabendazole resistance in nematodes","volume":"2","author":"Le Jambre","year":"1976","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0160","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/jlb.59.2.152","article-title":"Role of CSB\/p38\/RK stress response kinase in LPS and cytokine signaling mechanisms","volume":"59","author":"Lee","year":"1996","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0165","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/372739a0","article-title":"A protein kinase involved in the regulation of inflammatory cytokine biosynthesis","volume":"372","author":"Lee","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.ijpara.2015.01.007_b0170","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/S0960-894X(00)00698-3","article-title":"Semi-synthesis of 2-deoxo- and 3-epiparaherquamide A","volume":"11","author":"Lee","year":"2001","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.ijpara.2015.01.007_b0175","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.ddtec.2004.11.007","article-title":"Lead- and drug-like compounds: the rule-of-five revolution","volume":"1","author":"Lipinski","year":"2004","journal-title":"Drug Discov. Today"},{"key":"10.1016\/j.ijpara.2015.01.007_b0180","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pntd.0001494","article-title":"WormAssay: a novel computer application for whole-plate motion-based screening of macroscopic parasites","volume":"6","author":"Marcellino","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.ijpara.2015.01.007_b0185","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/BF02268963","article-title":"Larval paralysis as an in vitro assay of levamisole and morantel tartrate resistance in Ostertagia","volume":"3","author":"Martin","year":"1979","journal-title":"Vet. Res. Commun."},{"key":"10.1016\/j.ijpara.2015.01.007_b0190","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/S0020-7519(02)00008-5","article-title":"HcSTK, a Caenorhabditis elegans PAR-1 homologue from the parasitic nematode, Haemonchus contortus","volume":"32","author":"Nikolaou","year":"2002","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0195","first-page":"185","article-title":"Repurposing drugs for the treatment and control of helminth infections","volume":"4","author":"Panic","year":"2014","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0200","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/pim.12037","article-title":"Automated Imaging and other developments in whole-organism anthelmintic screening","volume":"35","author":"Paveley","year":"2013","journal-title":"Parasite Immunol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0205","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pntd.0001762","article-title":"Whole organism high-content screening by label-free, image-based Bayesian classification for parasitic diseases","volume":"6","author":"Paveley","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.ijpara.2015.01.007_b0210","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.2174\/156802608786264245","article-title":"Small molecule p38 MAP kinase inhibitors for the treatment of inflammatory diseases: novel structures and developments during 2006\u20132008","volume":"8","author":"Pettus","year":"2008","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.ijpara.2015.01.007_b0215","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/452157a","article-title":"Drug discovery: fresh hope to can the worms","volume":"452","author":"Prichard","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.ijpara.2015.01.007_b0220","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/B978-0-12-407705-8.00004-5","article-title":"Next-generation molecular-diagnostic tools for gastrointestinal nematodes of livestock, with an emphasis on small ruminants: a turning point?","volume":"83","author":"Roeber","year":"2013","journal-title":"Adv. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0225","first-page":"135","article-title":"Identification and profiling of nematicidal compounds in veterinary parasitology","author":"Rohwer","year":"2012"},{"key":"10.1016\/j.ijpara.2015.01.007_b0230","doi-asserted-by":"crossref","first-page":"R89","DOI":"10.1186\/gb-2013-14-8-r89","article-title":"The genome and developmental transcriptome of the strongylid nematode Haemonchus contortus","volume":"14","author":"Schwarz","year":"2013","journal-title":"Genome Biol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0235","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.vetpar.2013.07.037","article-title":"Lack of efficacy of monepantel against Teladorsagia circumcincta and Trichostrongylus colubriformis","volume":"198","author":"Scott","year":"2013","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0240","doi-asserted-by":"crossref","first-page":"E3689","DOI":"10.1073\/pnas.1405801111","article-title":"The role of PI3K\/AKT-related PIP5K1\u03b1 and the discovery of its selective inhibitor for treatment of advanced prostate cancer","volume":"111","author":"Semenas","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.ijpara.2015.01.007_b0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pntd.0000885","article-title":"A novel high throughput assay for anthelmintic drug screening and resistance diagnosis by real-time monitoring of parasite motility","volume":"4","author":"Smout","year":"2010","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.ijpara.2015.01.007_b0250","doi-asserted-by":"crossref","first-page":"127","DOI":"10.2307\/3276403","article-title":"The development of Haemonchus contortus to the fourth stage in vitro","volume":"52","author":"Sommerville","year":"1966","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0255","first-page":"233","article-title":"Utilization of computer processed high definition video imaging for measuring motility of microscopic nematode stages on a quantitative scale: \u201cThe Worminator\u201d","volume":"4","author":"Storey","year":"2014","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0260","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/ng.2875","article-title":"Genome of the human hookworm Necator americanus","volume":"46","author":"Tang","year":"2014","journal-title":"Nat. Genet."},{"key":"10.1016\/j.ijpara.2015.01.007_b0265","doi-asserted-by":"crossref","first-page":"e1003149","DOI":"10.1371\/journal.ppat.1003149","article-title":"Using existing drugs as leads for broad spectrum anthelmintics targeting protein kinases","volume":"9","author":"Taylor","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijpara.2015.01.007_b0270","first-page":"1725","article-title":"P38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans","volume":"3","author":"Troemel","year":"2006","journal-title":"PLoS Genet."},{"key":"10.1016\/j.ijpara.2015.01.007_b0275","unstructured":"Veglia, F., 1915. The anatomy and life history of the Haemonchus contortus (Rud.); 3rd and 4th Rep. Dir. Vet. Res., Union S. Afr., 347\u2013500."},{"key":"10.1016\/j.ijpara.2015.01.007_b0280","first-page":"131","article-title":"Haemonchus contortus: parasite problem no. 1 from tropics - Polar Circle. Problems and prospects for control based on epidemiology","volume":"22","author":"Waller","year":"2005","journal-title":"Trop. Biomed."},{"key":"10.1016\/j.ijpara.2015.01.007_b0285","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/S0020-7519(02)00061-9","article-title":"Pyridinylimidazole p38 mitogen-activated protein kinase inhibitors block intracellular Toxoplasma gondii replication","volume":"32","author":"Wei","year":"2002","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0290","doi-asserted-by":"crossref","first-page":"4324","DOI":"10.1128\/AAC.00680-07","article-title":"Drugs designed to inhibit human p38 mitogen-activated protein kinase activation treat Toxoplasma gondii and Encephalitozoon cuniculi infection","volume":"51","author":"Wei","year":"2007","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijpara.2015.01.007_b0295","doi-asserted-by":"crossref","first-page":"873","DOI":"10.2174\/138920112800399239","article-title":"Resistance to macrocyclic lactones","volume":"13","author":"Wolstenholme","year":"2012","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0300","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.pt.2004.07.010","article-title":"Drug resistance in veterinary helminths","volume":"20","author":"Wolstenholme","year":"2004","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.ijpara.2015.01.007_b0305","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1177\/108705719900400206","article-title":"A simple statistical parameter for use in evaluation and validation of high throughput screening assays","volume":"4","author":"Zhang","year":"1999","journal-title":"J. Biomol. Screen."}],"container-title":["International Journal for Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751915000417?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751915000417?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T14:41:53Z","timestamp":1598798513000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020751915000417"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":61,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["S0020751915000417"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpara.2015.01.007","relation":{},"ISSN":["0020-7519"],"issn-type":[{"value":"0020-7519","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Low cost whole-organism screening of compounds for anthelmintic activity","name":"articletitle","label":"Article Title"},{"value":"International Journal for Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpara.2015.01.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Australian Society for Parasitology Inc. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}