{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T07:56:40Z","timestamp":1762761400928,"version":"3.44.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["ZonMW-VIDI-016.146.352"],"award-info":[{"award-number":["ZonMW-VIDI-016.146.352"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015084","name":"Lung Foundation Netherlands","doi-asserted-by":"publisher","award":["3.2.10.072"],"award-info":[{"award-number":["3.2.10.072"]}],"id":[{"id":"10.13039\/501100015084","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal for Parasitology"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.ijpara.2017.02.002","type":"journal-article","created":{"date-parts":[[2017,4,4]],"date-time":"2017-04-04T00:22:41Z","timestamp":1491265361000},"page":"545-554","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function"],"prefix":"10.1016","volume":"47","author":[{"given":"L.E.P.M.","family":"van der Vlugt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Obieglo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ozir-Fazalalikhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Sparwasser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Haeberlein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.H.","family":"Smits","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpara.2017.02.002_b0005","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/j.jaci.2010.01.018","article-title":"Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model","volume":"125","author":"Amu","year":"2010","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0010","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1086\/653828","article-title":"Increases in levels of schistosome-specific immunoglobulin E and CD23(+) B cells in a cohort of Kenyan children undergoing repeated treatment and reinfection with Schistosoma mansoni","volume":"202","author":"Black","year":"2010","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpara.2017.02.002_b0015","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.immuni.2009.11.009","article-title":"CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients","volume":"32","author":"Blair","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.ijpara.2017.02.002_b0020","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.jneuroim.2006.10.006","article-title":"PD-1\/PD-L1, but not PD-1\/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis","volume":"182","author":"Carter","year":"2007","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0025","doi-asserted-by":"crossref","first-page":"R32","DOI":"10.1186\/ar3736","article-title":"Interleukin-10 produced by B cells is crucial for the suppression of Th17\/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis","volume":"14","author":"Carter","year":"2012","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.ijpara.2017.02.002_b0030","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1038\/nature06306","article-title":"The inhibitory cytokine IL-35 contributes to regulatory T-cell function","volume":"450","author":"Collison","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.ijpara.2017.02.002_b0035","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1146\/annurev.iy.08.040190.003203","article-title":"Fc epsilon RII\/CD23: the low affinity receptor for IgE","volume":"8","author":"Conrad","year":"1990","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0040","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/ana.21438","article-title":"Helminth infections associated with multiple sclerosis induce regulatory B cells","volume":"64","author":"Correale","year":"2008","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0045","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1002\/eji.201141581","article-title":"Tim-1 regulates Th2 responses in an airway hypersensitivity model","volume":"42","author":"Curtiss","year":"2012","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0050","doi-asserted-by":"crossref","first-page":"e0121660","DOI":"10.1371\/journal.pone.0121660","article-title":"B cells play key roles in th2-type airway immune responses in mice exposed to natural airborne allergens","volume":"10","author":"Drake","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpara.2017.02.002_b0055","doi-asserted-by":"crossref","first-page":"529","DOI":"10.4049\/jimmunol.1303247","article-title":"B cells regulate CD4+ T cell responses to papain following B cell receptor-independent papain uptake","volume":"193","author":"Dwyer","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0060","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1002\/eji.200940109","article-title":"Helminths and dendritic cells: sensing and regulating via pattern recognition receptors, Th2 and Treg responses","volume":"40","author":"Everts","year":"2010","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0065","doi-asserted-by":"crossref","first-page":"2999","DOI":"10.4049\/jimmunol.1401225","article-title":"IL-4-secreting secondary T follicular helper (Tfh) cells arise from memory T cells, not persisting Tfh cells, through a B cell-dependent mechanism","volume":"194","author":"Fairfax","year":"2015","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0070","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1038\/nri2039","article-title":"Suppression of TH2-type allergic reactions by helminth infection","volume":"7","author":"Fallon","year":"2007","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0075","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1093\/intimm\/dxh217","article-title":"B cells play a regulatory role in mice infected with the L3 of Brugia pahangi","volume":"17","author":"Gillan","year":"2005","journal-title":"Int. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0080","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.transproceed.2013.08.075","article-title":"Regulatory B cells: the new \u201cit\u201d cell","volume":"46","author":"Goode","year":"2014","journal-title":"Transplant. Proc."},{"key":"10.1016\/j.ijpara.2017.02.002_b0085","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1365-2249.1993.tb05981.x","article-title":"Ascaris reinfection of slum children: relation with the IgE response","volume":"94","author":"Hagel","year":"1993","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0090","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/1465-9921-12-42","article-title":"Antigen-Specific IgG ameliorates allergic airway inflammation via Fcgamma receptor IIB on dendritic cells","volume":"12","author":"Ishikawa","year":"2011","journal-title":"Respir. Res."},{"key":"10.1016\/j.ijpara.2017.02.002_b0095","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.autrev.2011.11.018","article-title":"Human CD19(+)CD25(high) B regulatory cells suppress proliferation of CD4(+) T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells","volume":"11","author":"Kessel","year":"2012","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.ijpara.2017.02.002_b0100","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1093\/intimm\/10.9.1377","article-title":"The expression of murine B cell CD23, in vivo, is regulated by its ligand, IgE","volume":"10","author":"Kisselgof","year":"1998","journal-title":"Int. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0105","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1084\/jem.20061852","article-title":"Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease","volume":"204","author":"Lahl","year":"2007","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.ijpara.2017.02.002_b0110","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1089\/jir.2010.0020","article-title":"Allergen-specific transforming growth factor-beta-producing CD19+CD5+ regulatory B-cell (Br 3) responses in human late eczematous allergic reactions to cow's milk","volume":"31","author":"Lee","year":"2011","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.ijpara.2017.02.002_b0115","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.4049\/jimmunol.1400149","article-title":"Dendritic cells and B cells: unexpected partners in Th2 development","volume":"193","author":"Leon","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0120","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev.immunol.24.021605.090737","article-title":"Transforming growth factor-beta regulation of immune responses","volume":"24","author":"Li","year":"2006","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0125","doi-asserted-by":"crossref","first-page":"e3129","DOI":"10.1371\/journal.pone.0003129","article-title":"B cell antigen presentation promotes Th2 responses and immunopathology during chronic allergic lung disease","volume":"3","author":"Lindell","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpara.2017.02.002_b0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cellimm.2008.01.004","article-title":"Regulatory conversation between antigen presenting cells and regulatory T cells enhance immune suppression","volume":"250","author":"Mahnke","year":"2007","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0135","doi-asserted-by":"crossref","first-page":"3447","DOI":"10.4049\/jimmunol.178.6.3447","article-title":"B cell regulation of CD4+CD25+ T regulatory cells and IL-10 via B7 is essential for recovery from experimental autoimmune encephalomyelitis","volume":"178","author":"Mann","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0140","doi-asserted-by":"crossref","first-page":"2780","DOI":"10.4049\/jimmunol.1300649","article-title":"Peritoneal cavity regulatory B cells (B10 cells) modulate IFN-gamma+CD4+ T cell numbers during colitis development in mice","volume":"191","author":"Maseda","year":"2013","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0145","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1128\/CMR.05040-11","article-title":"Helminth infections and host immune regulation","volume":"25","author":"McSorley","year":"2012","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.ijpara.2017.02.002_b0150","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1093\/intimm\/dxv033","article-title":"IL-10-independent regulatory B-cell subsets and mechanisms of action","volume":"27","author":"Ray","year":"2015","journal-title":"Int. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0155","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/j.immuni.2015.04.005","article-title":"Regulatory B cells: origin, phenotype, and function","volume":"42","author":"Rosser","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.ijpara.2017.02.002_b0160","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.jaut.2014.01.032","article-title":"IL-10-producing regulatory B cells induced by IL-33 (Breg(IL-33)) effectively attenuate mucosal inflammatory responses in the gut","volume":"50","author":"Sattler","year":"2014","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.ijpara.2017.02.002_b0165","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1038\/nature12979","article-title":"IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases","volume":"507","author":"Shen","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.ijpara.2017.02.002_b0170","doi-asserted-by":"crossref","first-page":"e15","DOI":"10.1017\/S1462399408000707","article-title":"Mechanisms in allergic airway inflammation - lessons from studies in the mouse","volume":"10","author":"Shum","year":"2008","journal-title":"Expert Rev. Mol. Med."},{"key":"10.1016\/j.ijpara.2017.02.002_b0175","doi-asserted-by":"crossref","first-page":"7318","DOI":"10.4049\/jimmunol.180.11.7318","article-title":"Regulatory role of B cells in a murine model of allergic airway disease","volume":"180","author":"Singh","year":"2008","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0180","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1398-9995.2010.02458.x","article-title":"Role of PD-L1 and PD-L2 in allergic diseases and asthma","volume":"66","author":"Singh","year":"2011","journal-title":"Allergy"},{"key":"10.1016\/j.ijpara.2017.02.002_b0185","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.4049\/jimmunol.173.2.1240","article-title":"Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages","volume":"173","author":"Smith","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0190","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/j.jaci.2007.06.009","article-title":"Protective effect of Schistosoma mansoni infection on allergic airway inflammation depends on the intensity and chronicity of infection","volume":"120","author":"Smits","year":"2007","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0195","doi-asserted-by":"crossref","first-page":"4811","DOI":"10.4049\/jimmunol.176.8.4811","article-title":"Differential T cell-mediated regulation of CD23 (Fc epsilonRII) in B cells and follicular dendritic cells","volume":"176","author":"Sukumar","year":"2006","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0200","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1172\/JCI36534","article-title":"Th2 cell hyporesponsiveness during chronic murine schistosomiasis is cell intrinsic and linked to GRAIL expression","volume":"119","author":"Taylor","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ijpara.2017.02.002_b0205","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.4049\/jimmunol.167.2.1081","article-title":"Lipopolysaccharide-activated B cells down-regulate Th1 immunity and prevent autoimmune diabetes in nonobese diabetic mice","volume":"167","author":"Tian","year":"2001","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0210","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/j.jaci.2013.01.014","article-title":"IgG4 production is confined to human IL-10-producing regulatory B cells that suppress antigen-specific immune responses","volume":"131","author":"van de Veen","year":"2013","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0215","doi-asserted-by":"crossref","first-page":"e30883","DOI":"10.1371\/journal.pone.0030883","article-title":"Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells","volume":"7","author":"van der Vlugt","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpara.2017.02.002_b0220","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/cea.12238","article-title":"CD24(hi)CD27(+) B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide","volume":"44","author":"van der Vlugt","year":"2014","journal-title":"Clin. Exp. Allergy"},{"key":"10.1016\/j.ijpara.2017.02.002_b0225","doi-asserted-by":"crossref","first-page":"e1003215","DOI":"10.1371\/journal.ppat.1003215","article-title":"Th2 cell-intrinsic hypo-responsiveness determines susceptibility to helminth infection","volume":"9","author":"van der Werf","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijpara.2017.02.002_b0230","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/nm.3554","article-title":"Interleukin-35 induces regulatory B cells that suppress autoimmune disease","volume":"20","author":"Wang","year":"2014","journal-title":"Nat. Med."},{"key":"10.1016\/j.ijpara.2017.02.002_b0235","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1002\/eji.200939721","article-title":"Helminth-induced CD19+CD23hi B cells modulate experimental allergic and autoimmune inflammation","volume":"40","author":"Wilson","year":"2010","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.ijpara.2017.02.002_b0240","doi-asserted-by":"crossref","first-page":"12105","DOI":"10.1073\/pnas.1120914109","article-title":"Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice","volume":"109","author":"Xiao","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."}],"container-title":["International Journal for Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002075191730098X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002075191730098X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T14:00:22Z","timestamp":1758117622000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002075191730098X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":48,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["S002075191730098X"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpara.2017.02.002","relation":{},"ISSN":["0020-7519"],"issn-type":[{"type":"print","value":"0020-7519"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function","name":"articletitle","label":"Article Title"},{"value":"International Journal for Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpara.2017.02.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Australian Society for Parasitology. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}