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Sci."},{"key":"10.1016\/j.ijpara.2020.07.010_b0505","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.1093\/bioinformatics\/bth195","article-title":"The DISOPRED server for the prediction of protein disorder","volume":"20","author":"Ward","year":"2004","journal-title":"Bioinformatics"},{"issue":"1","key":"10.1016\/j.ijpara.2020.07.010_b0510","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1093\/nar\/29.1.70","article-title":"FULL-malaria: a database for a full-length enriched cDNA library from human malaria parasite, Plasmodium falciparum","volume":"29","author":"Watanabe","year":"2001","journal-title":"Nucleic Acids Res."},{"issue":"W1","key":"10.1016\/j.ijpara.2020.07.010_b0515","doi-asserted-by":"crossref","first-page":"W296","DOI":"10.1093\/nar\/gky427","article-title":"SWISS-MODEL: homology modelling of protein structures and complexes","volume":"46","author":"Waterhouse","year":"2018","journal-title":"Nucleic Acids Res."},{"issue":"1","key":"10.1016\/j.ijpara.2020.07.010_b0520","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1021\/bi952037f","article-title":"Asp537 and Asp812 in bacteriophage T7 RNA polymerase as metal ion-binding sites studied by EPR, flow-dialysis, and transcription","volume":"35","author":"Woody","year":"1996","journal-title":"Biochemistry"},{"issue":"5","key":"10.1016\/j.ijpara.2020.07.010_b0525","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1093\/nar\/20.5.1053","article-title":"Assignment of a yeast protein necessary for mitochondrial transcription initiation","volume":"20","author":"Xu","year":"1992","journal-title":"Nucleic Acids Res."},{"issue":"9","key":"10.1016\/j.ijpara.2020.07.010_b0530","article-title":"Yeast mitochondrial transcription factor Mtf1 determines the precision of promoter-directed initiation of RNA polymerase Rpo41","volume":"10","author":"Yang","year":"2015","journal-title":"PLoS ONE"},{"issue":"6388","key":"10.1016\/j.ijpara.2020.07.010_b0535","doi-asserted-by":"crossref","DOI":"10.1126\/science.aap7847","article-title":"Uncovering the essential genes of the human malaria parasite Plasmodium falciparum by saturation mutagenesis","volume":"360","author":"Zhang","year":"2018","journal-title":"Science"},{"issue":"1\u20132","key":"10.1016\/j.ijpara.2020.07.010_b0540","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0378-1119(01)00776-4","article-title":"Deciphering apicoplast targeting signals - Feature extraction from nuclear-encoded precursors of Plasmodium falciparum apicoplast proteins","volume":"280","author":"Zuegge","year":"2001","journal-title":"Gene"}],"container-title":["International Journal for Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751920302526?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751920302526?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T14:05:31Z","timestamp":1758117931000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020751920302526"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":106,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S0020751920302526"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpara.2020.07.010","relation":{},"ISSN":["0020-7519"],"issn-type":[{"value":"0020-7519","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PfKsgA1 functions as a transcription initiation factor and interacts with the N-terminal region of the mitochondrial RNA polymerase of Plasmodium falciparum","name":"articletitle","label":"Article Title"},{"value":"International Journal for Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpara.2020.07.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Australian Society for Parasitology. 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