{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T16:21:53Z","timestamp":1762186913460,"version":"build-2065373602"},"reference-count":64,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["10201"],"award-info":[{"award-number":["10201"]}],"id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001412","name":"Council of Scientific and Industrial Research, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","award":["CRG\/2020\/004443","EMR\/2016\/001880"],"award-info":[{"award-number":["CRG\/2020\/004443","EMR\/2016\/001880"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal for Parasitology"],"published-print":{"date-parts":[[2021,9]]},"DOI":"10.1016\/j.ijpara.2021.02.007","type":"journal-article","created":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T04:56:06Z","timestamp":1626324966000},"page":"841-853","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Biochemical characterization of Recombinase A from Wolbachia endosymbiont of filarial nematode Brugia malayi (wBmRecA)"],"prefix":"10.1016","volume":"51","author":[{"given":"Mamta","family":"Gangwar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruchi","family":"Jha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manish","family":"Goyal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mrigank","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpara.2021.02.007_b0005","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.chembiol.2016.02.010","article-title":"RecA inhibitors potentiate antibiotic activity and block evolution of antibiotic resistance","volume":"23","author":"Alam","year":"2016","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0010","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1756-3305-5-12","article-title":"Retarded Onchocerca volvulus L1 to L3 larval development in the Simulium damnosum vector after anti-wolbachial treatment of the human host","volume":"5","author":"Albers","year":"2012","journal-title":"Parasites Vectors"},{"key":"10.1016\/j.ijpara.2021.02.007_b0015","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0031-6997(25)00026-2","article-title":"What is synergy?","volume":"41","author":"Berenbaum","year":"1989","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ijpara.2021.02.007_b0020","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/1469-0691.12069","article-title":"The symbiotic role of Wolbachia in Onchocercidae and its impact on filariasis","volume":"19","author":"Bouchery","year":"2013","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.ijpara.2021.02.007_b0025","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1475-2883-2-10","article-title":"Obligatory symbiotic Wolbachia endobacteria are absent from Loa loa","volume":"2","author":"Buttner","year":"2003","journal-title":"Filaria J."},{"key":"10.1016\/j.ijpara.2021.02.007_b0030","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1186\/s13071-014-0466-x","article-title":"The global distribution and transmission limits of lymphatic filariasis: past and present","volume":"7","author":"Cano","year":"2014","journal-title":"Parasites Vectors"},{"key":"10.1016\/j.ijpara.2021.02.007_b0035","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/nature06971","article-title":"Mechanism of homologous recombination from the RecA-ssDNA\/dsDNA structures","volume":"453","author":"Chen","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.ijpara.2021.02.007_b0040","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/S0014-4894(03)00063-8","article-title":"Brugia pahangi and Wolbachia: the kinetics of bacteria elimination, worm viability, and host responses following tetracycline treatment","volume":"103","author":"Chirgwin","year":"2003","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0045","doi-asserted-by":"crossref","first-page":"e176","DOI":"10.1371\/journal.pbio.0030176","article-title":"Inhibition of mutation and combating the evolution of antibiotic resistance","volume":"3","author":"Cirz","year":"2005","journal-title":"PLoS Biol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0050","first-page":"288","article-title":"Determinants of parasite drug resistance in human lymphatic filariasis","volume":"29","author":"Cobo","year":"2016","journal-title":"Revista espanola de quimioterapia: publicacion oficial de la Sociedad Espanola de Quimioterapia"},{"key":"10.1016\/j.ijpara.2021.02.007_b0055","doi-asserted-by":"crossref","first-page":"580","DOI":"10.2307\/3283163","article-title":"Recovery, distribution, and development of Acanthocheilonema viteae third- and early fourth-stage larvae in adult jirds","volume":"77","author":"Eisenbeiss","year":"1991","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0060","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.molbiopara.2004.06.012","article-title":"Quantification of Wolbachia bacteria in Brugia malayi through the nematode lifecycle","volume":"137","author":"Fenn","year":"2004","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0065","doi-asserted-by":"crossref","first-page":"4097","DOI":"10.1128\/AAC.48.11.4097-4102.2004","article-title":"Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum","volume":"48","author":"Fivelman","year":"2004","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijpara.2021.02.007_b0070","doi-asserted-by":"crossref","first-page":"e121","DOI":"10.1371\/journal.pbio.0030121","article-title":"The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode","volume":"3","author":"Foster","year":"2005","journal-title":"PLoS Biol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0075","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.vaccine.2018.12.015","article-title":"Immunogenicity and protective efficacy of Recombinase A from Wolbachia endosymbiont of filarial nematode Brugia malayi (wBmRecA)","volume":"37","author":"Gangwar","year":"2019","journal-title":"Vaccine"},{"key":"10.1016\/j.ijpara.2021.02.007_b0080","doi-asserted-by":"crossref","first-page":"53","DOI":"10.2174\/187153012799279108","article-title":"Wolbachia and its implications for the immunopathology of filariasis","volume":"12","author":"Genchi","year":"2012","journal-title":"Endocrine Metabol. Immune Disord. Drug Targets"},{"key":"10.1016\/j.ijpara.2021.02.007_b0085","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1093\/nar\/gkr821","article-title":". Identification and molecular characterization of an Alba-family protein from human malaria parasite Plasmodium falciparum","volume":"40","author":"Goyal","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ijpara.2021.02.007_b0090","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.ijpara.2009.01.006","article-title":"An endosymbiotic bacterium in a plant-parasitic nematode: member of a new Wolbachia supergroup","volume":"39","author":"Haegeman","year":"2009","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0095","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.4049\/jimmunol.178.2.1068","article-title":"Innate immune responses to endosymbiotic Wolbachia bacteria in Brugia malayi and Onchocerca volvulus are dependent on TLR2, TLR6, MyD88, and Mal, but not TLR4, TRIF, or TRAM","volume":"178","author":"Hise","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0100","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1046\/j.1462-5822.2003.00350.x","article-title":"The role of endosymbiotic Wolbachia bacteria in filarial disease","volume":"6","author":"Hise","year":"2004","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0105","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1097\/QCO.0b013e328315cde7","article-title":"Filariasis: new drugs and new opportunities for lymphatic filariasis and onchocerciasis","volume":"21","author":"Hoerauf","year":"2008","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.ijpara.2021.02.007_b0110","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S1286-4579(03)00026-1","article-title":"Doxycycline in the treatment of human onchocerciasis: kinetics of Wolbachia endobacteria reduction and of inhibition of embryogenesis in female Onchocerca worms","volume":"5","author":"Hoerauf","year":"2003","journal-title":"Microbes Infect."},{"key":"10.1016\/j.ijpara.2021.02.007_b0115","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1172\/JCI4768","article-title":"Tetracycline therapy targets intracellular bacteria in the filarial nematode Litomosoides sigmodontis and results in filarial infertility","volume":"103","author":"Hoerauf","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ijpara.2021.02.007_b0120","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1111\/j.1469-0691.2011.03586.x","article-title":"Filariasis in Africa\u2013treatment challenges and prospects","volume":"17","author":"Hoerauf","year":"2011","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.ijpara.2021.02.007_b0125","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/0092-8674(81)90393-7","article-title":"Regulation of SOS functions: purification of E. coli LexA protein and determination of its specific site cleaved by the RecA protein","volume":"27","author":"Horii","year":"1981","journal-title":"Cell"},{"key":"10.1016\/j.ijpara.2021.02.007_b0130","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1073\/pnas.77.1.313","article-title":"Organization of the recA gene of Escherichia coli","volume":"77","author":"Horii","year":"1980","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"10.1016\/j.ijpara.2021.02.007_b0135","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/S1473-3099(16)30467-4","article-title":"Effectiveness of a triple-drug regimen for global elimination of lymphatic filariasis: a modelling study","volume":"17","author":"Irvine","year":"2017","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ijpara.2021.02.007_b0140","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/1756-3305-3-99","article-title":"Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes","volume":"3","author":"Johnston","year":"2010","journal-title":"Parasites Vectors"},{"key":"10.1016\/j.ijpara.2021.02.007_b0145","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1128\/jb.178.7.1881-1894.1996","article-title":"Evolutionary conservation of RecA genes in relation to protein structure and function","volume":"178","author":"Karlin","year":"1996","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0150","doi-asserted-by":"crossref","first-page":"A54","DOI":"10.1016\/S0167-5699(05)80016-7","article-title":"Regulation of the immune response in lymphatic filariasis and onchocerciasis","volume":"12","author":"King","year":"1991","journal-title":"Immunol. Today"},{"key":"10.1016\/j.ijpara.2021.02.007_b0155","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1056\/NEJMoa1706854","article-title":"A trial of a triple-drug treatment for lymphatic filariasis","volume":"379","author":"King","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijpara.2021.02.007_b0160","doi-asserted-by":"crossref","first-page":"e2447","DOI":"10.1371\/journal.pntd.0002447","article-title":"A review of factors that influence individual compliance with mass drug administration for elimination of lymphatic filariasis","volume":"7","author":"Krentel","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.ijpara.2021.02.007_b0165","doi-asserted-by":"crossref","first-page":"e1189","DOI":"10.1371\/journal.pone.0001189","article-title":"Mining predicted essential genes of Brugia malayi for nematode drug targets","volume":"2","author":"Kumar","year":"2007","journal-title":"PLoS ONE"},{"key":"10.1016\/j.ijpara.2021.02.007_b0170","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1016\/j.micinf.2012.08.006","article-title":"Recombinant trehalose-6-phosphate phosphatase of Brugia malayi cross-reacts with human Wuchereria bancrofti immune sera and engenders a robust protective outcome in mice","volume":"14","author":"Kushwaha","year":"2012","journal-title":"Microbes Infect."},{"key":"10.1016\/j.ijpara.2021.02.007_b0175","doi-asserted-by":"crossref","first-page":"e1002351","DOI":"10.1371\/journal.ppat.1002351","article-title":"Anti-filarial activity of antibiotic therapy is due to extensive apoptosis after Wolbachia depletion from filarial nematodes","volume":"7","author":"Landmann","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijpara.2021.02.007_b0180","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1098\/rspb.2000.1110","article-title":"Macrofilaricidal activity of tetracycline against the filarial nematode Onchocerca ochengi: elimination of Wolbachia precedes worm death and suggests a dependent relationship","volume":"267","author":"Langworthy","year":"2000","journal-title":"Proc. Biol. Sci."},{"key":"10.1016\/j.ijpara.2021.02.007_b0185","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.chembiol.2012.11.009","article-title":"A selective inhibitor of heme biosynthesis in endosymbiotic bacteria elicits antifilarial activity in vitro","volume":"20","author":"Lentz","year":"2013","journal-title":"Chem. Biol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0190","doi-asserted-by":"crossref","first-page":"e1411","DOI":"10.1371\/journal.pntd.0001411","article-title":"Targeting the Wolbachia cell division protein FtsZ as a new approach for antifilarial therapy","volume":"5","author":"Li","year":"2011","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.ijpara.2021.02.007_b0195","doi-asserted-by":"crossref","first-page":"10328","DOI":"10.1073\/pnas.0604232103","article-title":"Origins and evolution of the recA\/RAD51 gene family: evidence for ancient gene duplication and endosymbiotic gene transfer","volume":"103","author":"Lin","year":"2006","journal-title":"Proc. Nat. Acad .Sci. USA"},{"key":"10.1016\/j.ijpara.2021.02.007_b0200","doi-asserted-by":"crossref","first-page":"e76","DOI":"10.1371\/journal.pntd.0000076","article-title":"Ivermectin resistance in Onchocerca volvulus: toward a genetic basis","volume":"1","author":"Lustigman","year":"2007","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.ijpara.2021.02.007_b0205","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.molbiopara.2004.01.006","article-title":"Population dynamics of Wolbachia bacterial endosymbionts in Brugia malayi","volume":"135","author":"McGarry","year":"2004","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0210","doi-asserted-by":"crossref","first-page":"e11029","DOI":"10.1371\/journal.pone.0011029","article-title":"Endosymbiont DNA in endobacteria-free filarial nematodes indicates ancient horizontal genetic transfer","volume":"5","author":"McNulty","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.ijpara.2021.02.007_b0215","doi-asserted-by":"crossref","first-page":"19913","DOI":"10.1073\/pnas.1112646108","article-title":"Effects of pressure and temperature on the binding of RecA protein to single-stranded DNA","volume":"108","author":"Merrin","year":"2011","journal-title":"Proc Nat. Acad. Sci. USA"},{"key":"10.1016\/j.ijpara.2021.02.007_b0220","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1017\/S0031182000066646","article-title":"Re-assessing the global prevalence and distribution of lymphatic filariasis","volume":"112","author":"Michael","year":"1996","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2021.02.007_b0225","doi-asserted-by":"crossref","DOI":"10.1093\/femspd\/ftw072","article-title":"UDP-galactopyranose mutase, a potential drug target against human pathogenic nematode Brugia malayi","volume":"74","author":"Misra","year":"2016","journal-title":"Pathog. Dis."},{"key":"10.1016\/j.ijpara.2021.02.007_b0230","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1007\/s00436-011-2380-x","article-title":"Gedunin and photogedunin of Xylocarpus granatum possess antifilarial activity against human lymphatic filarial parasite Brugia malayi in experimental rodent host","volume":"109","author":"Misra","year":"2011","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.ijpara.2021.02.007_b0235","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.ijpara.2021.02.007_b0240","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1093\/jac\/dku080","article-title":"Suramin is a potent and selective inhibitor of Mycobacterium tuberculosis RecA protein and the SOS response: RecA as a potential target for antibacterial drug discovery","volume":"69","author":"Nautiyal","year":"2014","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.ijpara.2021.02.007_b0245","doi-asserted-by":"crossref","unstructured":"Schiefer, A., Schmitz, A., Schaberle, T.F., Specht, S., Lammer, C., Johnston, K.L., Vassylyev, D.G., Konig, G.M., Hoerauf, A., Pfarr, K., 2012. Corallopyronin A specifically targets and depletes essential obligate Wolbachia endobacteria from filarial nematodes in vivo. J Infect Dis 206, 249-257.","DOI":"10.1093\/infdis\/jis341"},{"key":"10.1016\/j.ijpara.2021.02.007_b0250","doi-asserted-by":"crossref","first-page":"234","DOI":"10.4269\/ajtmh.2005.73.234","article-title":"Detection of benzimidazole resistance-associated mutations in the filarial nematode Wuchereria bancrofti and evidence for selection by albendazole and ivermectin combination treatment","volume":"73","author":"Schwab","year":"2005","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpara.2021.02.007_b0255","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1017\/S0031182007002363","article-title":"An analysis of the population genetics of potential multi-drug resistance in Wuchereria bancrofti due to combination chemotherapy","volume":"134","author":"Schwab","year":"2007","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2021.02.007_b0260","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1093\/jac\/dkq542","article-title":"In vitro interactions between sitamaquine and amphotericin B, sodium stibogluconate, miltefosine, paromomycin and pentamidine against Leishmania donovani","volume":"66","author":"Seifert","year":"2011","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.ijpara.2021.02.007_b0265","doi-asserted-by":"crossref","first-page":"19842","DOI":"10.1038\/srep19842","article-title":"Essential proteins and possible therapeutic targets of Wolbachia endosymbiont and development of FiloBase\u2013a comprehensive drug target database for Lymphatic filariasis","volume":"6","author":"Sharma","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ijpara.2021.02.007_b0270","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s13199-010-0067-1","article-title":"The Wolbachia endosymbiont as an anti-filarial nematode target","volume":"51","author":"Slatko","year":"2010","journal-title":"Symbiosis"},{"key":"10.1016\/j.ijpara.2021.02.007_b0275","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0188-4409(02)00377-6","article-title":"Wolbachia endosymbiotic bacteria of filarial nematodes. A new insight into disease pathogenesis and control","volume":"33","author":"Taylor","year":"2002","journal-title":"Archives Med. Res."},{"key":"10.1016\/j.ijpara.2021.02.007_b0280","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0169-4758(99)01533-1","article-title":"Wolbachia bacteria of filarial nematodes","volume":"15","author":"Taylor","year":"1999","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.ijpara.2021.02.007_b0285","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1097\/00001432-200112000-00011","article-title":"A new approach to the treatment of filariasis","volume":"14","author":"Taylor","year":"2001","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.ijpara.2021.02.007_b0290","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1017\/S0031182013001108","article-title":"Anti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasis","volume":"141","author":"Taylor","year":"2014","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpara.2021.02.007_b0295","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1111\/cmi.12084","article-title":"Wolbachia filarial interactions","volume":"15","author":"Taylor","year":"2013","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0300","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1080\/00034983.2000.11813605","article-title":"Antibiotics and Wolbachia in filarial nematodes: antifilarial activity of rifampicin, oxytetracycline and chloramphenicol against Onchocerca gutturosa, Onchocerca lienalis and Brugia pahangi","volume":"94","author":"Townson","year":"2000","journal-title":"Annals Trop. Med. Parasitol."},{"key":"10.1016\/j.ijpara.2021.02.007_b0305","doi-asserted-by":"crossref","first-page":"E9712","DOI":"10.1073\/pnas.1710845114","article-title":"Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis","volume":"114","author":"Turner","year":"2017","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"10.1016\/j.ijpara.2021.02.007_b0310","doi-asserted-by":"crossref","first-page":"E1638","DOI":"10.1073\/pnas.1203519109","article-title":"Autophagy regulates Wolbachia populations across diverse symbiotic associations","volume":"109","author":"Voronin","year":"2012","journal-title":"Proc. Nat. Acad. Sci. USA"},{"key":"10.1016\/j.ijpara.2021.02.007_b0315","doi-asserted-by":"crossref","first-page":"e475","DOI":"10.1371\/journal.pntd.0000475","article-title":"The heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug target","volume":"3","author":"Wu","year":"2009","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.ijpara.2021.02.007_b0320","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1093\/nar\/26.2.650","article-title":"Binding of double-stranded DNA by Escherichia coli RecA protein monitored by a fluorescent dye displacement assay","volume":"26","author":"Zaitsev","year":"1998","journal-title":"Nucleic Acids Res."}],"container-title":["International Journal for Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751921002149?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751921002149?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T15:53:12Z","timestamp":1762185192000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020751921002149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":64,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["S0020751921002149"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpara.2021.02.007","relation":{},"ISSN":["0020-7519"],"issn-type":[{"type":"print","value":"0020-7519"}],"subject":[],"published":{"date-parts":[[2021,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biochemical characterization of Recombinase A from Wolbachia endosymbiont of filarial nematode Brugia malayi (wBmRecA)","name":"articletitle","label":"Article Title"},{"value":"International Journal for Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpara.2021.02.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Australian Society for Parasitology. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}