{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T06:50:40Z","timestamp":1792651840744,"version":"4.5.0"},"reference-count":19,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T00:00:00Z","timestamp":1701216000000},"content-version":"am","delay-in-days":424,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI132644"],"award-info":[{"award-number":["AI132644"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI129326"],"award-info":[{"award-number":["AI129326"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI130131"],"award-info":[{"award-number":["AI130131"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AI139898"],"award-info":[{"award-number":["AI139898"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal for Parasitology"],"published-print":{"date-parts":[[2022,10]]},"DOI":"10.1016\/j.ijpara.2022.07.001","type":"journal-article","created":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T12:29:03Z","timestamp":1658838543000},"page":"717-720","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Monocyte epigenetics and innate immunity to malaria: yet another level of complexity?"],"prefix":"10.1016","volume":"52","author":[{"given":"Katherine R.","family":"Dobbs","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arlene E.","family":"Dent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Embury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidney","family":"Ogolla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmily","family":"Koech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Midem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James W.","family":"Kazura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpara.2022.07.001_b0005","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1093\/cid\/ciy427","article-title":"Clinical implications of asymptomatic Plasmodium falciparum infections in Malawi","volume":"68","author":"Buchwald","year":"2019","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.ijpara.2022.07.001_b0010","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1093\/aje\/kwy213","article-title":"Association between age and Plasmodium falciparum infection dynamics","volume":"188","author":"Buchwald","year":"2019","journal-title":"Am. J. Epidemiol."},{"issue":"9","key":"10.1016\/j.ijpara.2022.07.001_b0015","article-title":"Prediction and analysis of essential genes using the enrichments of gene ontology and KEGG pathways","volume":"12","author":"Chen","year":"2017","journal-title":"PLoS ONE"},{"issue":"1","key":"10.1016\/j.ijpara.2022.07.001_b0020","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.pt.2012.10.002","article-title":"Monocytes and macrophages in malaria: protection or pathology?","volume":"29","author":"Chua","year":"2013","journal-title":"Trends Parasitol"},{"key":"10.1016\/j.ijpara.2022.07.001_b0025","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.95352","article-title":"Monocyte dysregulation and systemic inflammation during pediatric falciparum malaria","volume":"2","author":"Dobbs","year":"2017","journal-title":"JCI Insight"},{"issue":"1","key":"10.1016\/j.ijpara.2022.07.001_b0030","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/imr.12830","article-title":"Innate immunity to malaria-The role of monocytes","volume":"293","author":"Dobbs","year":"2020","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.ijpara.2022.07.001_b0035","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12979-021-00223-2","article-title":"Age-related differences in monocyte DNA methylation and immune function in healthy Kenyan adults and children","volume":"18","author":"Dobbs","year":"2021","journal-title":"Immun Ageing"},{"issue":"1","key":"10.1016\/j.ijpara.2022.07.001_b0040","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1128\/CMR.00025-08","article-title":"Acquired immunity to malaria","volume":"22","author":"Doolan","year":"2009","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.ijpara.2022.07.001_b0045","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1056\/NEJMc1805989","article-title":"The key role of epigenetics in human disease","volume":"379","author":"Feinberg","year":"2018","journal-title":"N. Engl. J. Med."},{"issue":"9","key":"10.1016\/j.ijpara.2022.07.001_b0050","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0045542","article-title":"The dynamics of natural Plasmodium falciparum infections","volume":"7","author":"Felger","year":"2012","journal-title":"PLoS ONE"},{"issue":"4","key":"10.1016\/j.ijpara.2022.07.001_b0055","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1009430","article-title":"Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype","volume":"17","author":"Guha","year":"2021","journal-title":"PLoS Pathog."},{"issue":"7","key":"10.1016\/j.ijpara.2022.07.001_b0060","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1038\/ni.f.205","article-title":"Immunity to malaria: more questions than answers","volume":"9","author":"Langhorne","year":"2008","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.ijpara.2022.07.001_b0065","doi-asserted-by":"crossref","first-page":"2888","DOI":"10.3389\/fimmu.2018.02888","article-title":"The rough guide to monocytes in malaria infection","volume":"9","author":"Ortega-Pajares","year":"2018","journal-title":"Front. Immunol."},{"issue":"6","key":"10.1016\/j.ijpara.2022.07.001_b0070","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/j.cell.2012.02.045","article-title":"Regulated noise in the epigenetic landscape of development and disease","volume":"148","author":"Pujadas","year":"2012","journal-title":"Cell"},{"issue":"4","key":"10.1016\/j.ijpara.2022.07.001_b0075","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.4049\/jimmunol.1701010","article-title":"Cutting edge: Plasmodium falciparum induces trained innate immunity","volume":"200","author":"Schrum","year":"2018","journal-title":"J. Immunol."},{"key":"10.1016\/j.ijpara.2022.07.001_b0080","doi-asserted-by":"crossref","first-page":"604553","DOI":"10.3389\/fmolb.2020.604553","article-title":"Controlled human malaria infection induces long-term functional changes in monocytes","volume":"7","author":"Walk","year":"2020","journal-title":"Front. Mol. Biosci."},{"issue":"10","key":"10.1016\/j.ijpara.2022.07.001_b0085","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005930","article-title":"Increased CD40 expression enhances early STING-mediated Type I interferon response and host survival in a rodent malaria model","volume":"12","author":"Yao","year":"2016","journal-title":"PLoS Pathog."},{"issue":"5","key":"10.1016\/j.ijpara.2022.07.001_b0090","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.immuni.2016.10.001","article-title":"Cross-regulation of two type I interferon signaling pathways in plasmacytoid dendritic cells controls anti-malaria immunity and host mortality","volume":"45","author":"Yu","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.ijpara.2022.07.001_b0095","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1105\/tpc.110.081695","article-title":"BSCTV C2 attenuates the degradation of SAMDC1 to suppress DNA methylation-mediated gene silencing in Arabidopsis","volume":"23","author":"Zhang","year":"2011","journal-title":"Plant Cell"}],"container-title":["International Journal for Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751922001023?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020751922001023?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T20:44:57Z","timestamp":1777409097000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020751922001023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":19,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["S0020751922001023"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpara.2022.07.001","relation":{},"ISSN":["0020-7519"],"issn-type":[{"value":"0020-7519","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Monocyte epigenetics and innate immunity to malaria: yet another level of complexity?","name":"articletitle","label":"Article Title"},{"value":"International Journal for Parasitology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpara.2022.07.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Australian Society for Parasitology. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}