{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T11:58:28Z","timestamp":1790078308109,"version":"4.0.1"},"reference-count":57,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,1,21]],"date-time":"2014-01-21T00:00:00Z","timestamp":1390262400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal for Parasitology: Drugs and Drug Resistance"],"published-print":{"date-parts":[[2014,8]]},"DOI":"10.1016\/j.ijpddr.2014.01.002","type":"journal-article","created":{"date-parts":[[2014,2,2]],"date-time":"2014-02-02T05:30:54Z","timestamp":1391319054000},"page":"71-76","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["High level expression of a glutamate-gated chloride channel gene in reproductive tissues of Brugia malayi may explain the sterilizing effect of ivermectin on filarial worms"],"prefix":"10.1016","volume":"4","author":[{"given":"Ben Wen","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy C.","family":"Rush","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary J.","family":"Weil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpddr.2014.01.002_b0015","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1080\/00034983.1985.11811889","article-title":"The chemotherapy of onchocerciasis X. An assessment of four single dose treatment regimes of MK-933 (ivermectin) in human onchocerciasis","volume":"79","author":"Awadzi","year":"1985","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0010","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0035-9203(99)90305-X","article-title":"The effects of high-dose ivermectin regimens on Onchocerca volvulus in onchocerciasis patients","volume":"93","author":"Awadzi","year":"1999","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0005","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1475-2883-5-11","article-title":"The Mectizan donation program \u2013 highlights from 2005","volume":"5","author":"Alleman","year":"2006","journal-title":"Filaria J."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0025","first-page":"19","article-title":"Ivermectin and moxidectin in two filarial systems: resistance of Monanema martini; inhibition of Litomosoides sigmodontis insemination","volume":"39","author":"Breton","year":"1997","journal-title":"Parassitologia"},{"issue":"Suppl.","key":"10.1016\/j.ijpddr.2014.01.002_b0035","doi-asserted-by":"crossref","first-page":"S133","DOI":"10.1017\/S0031182000006570","article-title":"Ivermectin: effectiveness in lymphatic filariasis","volume":"121","author":"Brown","year":"2000","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0030","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/j.ijpara.2007.03.009","article-title":"Faecal soiling and gastrointestinal helminth infection in lambs","volume":"37","author":"Broughan","year":"2007","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0020","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S1473-3099(08)70099-9","article-title":"Effect of single-dose ivermectin on Onchocerca volvulus: a systematic review and meta-analysis","volume":"8","author":"Basanez","year":"2008","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0050","first-page":"256","article-title":"The effect of repeated doses of ivermectin on adult female Onchocerca volvulus in Sierra Leone","volume":"43","author":"Chavasse","year":"1992","journal-title":"Trop. Med. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0045","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/0035-9203(93)90046-S","article-title":"Microfilariae recurrence in Polynesian Wuchereria bancrofti carriers treated with repeated single doses of 100 micrograms\/kg of ivermectin","volume":"87","author":"Cartel","year":"1993","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0055","first-page":"155","article-title":"Absence of sperm from the seminal receptacle of female Onchocerca volvulus following multiple doses of ivermectin","volume":"44","author":"Chavasse","year":"1993","journal-title":"Trop. Med. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0075","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/371707a0","article-title":"Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans","volume":"371","author":"Cully","year":"1994","journal-title":"Nature"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0065","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF02740637","article-title":"Inhibitory glutamate receptor channels","volume":"13","author":"Cleland","year":"1996","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0070","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0304-4017(01)00421-6","article-title":"The future of veterinary parasitology","volume":"98","author":"Coles","year":"2001","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0060","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1002\/ps.684","article-title":"Research on plant-parasitic nematode biology conducted by the United States department of agriculture\u2013agricultural research service","volume":"59","author":"Chitwood","year":"2003","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0040","doi-asserted-by":"crossref","first-page":"853","DOI":"10.2174\/138920112800399095","article-title":"History of avermectin and ivermectin, with notes on the history of other macrocyclic lactone antiparasitic agents","volume":"13","author":"Campbell","year":"2012","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0090","doi-asserted-by":"crossref","first-page":"657","DOI":"10.4269\/ajtmh.1990.43.657","article-title":"Effects of multiple monthly doses of ivermectin on adult Onchocerca volvulus","volume":"43","author":"Duke","year":"1990","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0100","first-page":"175","article-title":"The embryogenesis of Onchocerca volvulus over the first year after a single dose of ivermectin","volume":"42","author":"Duke","year":"1991","journal-title":"Trop. Med. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0095","doi-asserted-by":"crossref","first-page":"189","DOI":"10.4269\/ajtmh.1992.46.189","article-title":"Effects of three-month doses of ivermectin on adult Onchocerca volvulus","volume":"46","author":"Duke","year":"1992","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0080","doi-asserted-by":"crossref","first-page":"5867","DOI":"10.1093\/emboj\/16.19.5867","article-title":"Avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans","volume":"16","author":"Dent","year":"1997","journal-title":"Embo J."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0085","doi-asserted-by":"crossref","first-page":"2674","DOI":"10.1073\/pnas.97.6.2674","article-title":"The genetics of ivermectin resistance in Caenorhabditis elegans","volume":"97","author":"Dent","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0105","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.ijpara.2011.04.003","article-title":"Altered avr-14B gene transcription patterns in ivermectin-resistant isolates of the cattle parasites, Cooperia oncophora and Ostertagia ostertagi","volume":"41","author":"El-Abdellati","year":"2011","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0110","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0166-6851(03)00102-6","article-title":"Haemonchus contortus: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the antiparasitic drug ivermectin","volume":"129","author":"Forrester","year":"2003","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0115","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1097\/QCO.0b013e328010774c","article-title":"Ivermectin: uses and impact 20 years on","volume":"19","author":"Fox","year":"2006","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0135","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/0020-7519(91)90144-V","article-title":"Detection of resistance to ivermectin in Haemonchus contortus","volume":"21","author":"Gill","year":"1991","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0120","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1006\/expr.1993.1064","article-title":"Haemonchus contortus: ivermectin-induced paralysis of the pharynx","volume":"77","author":"Geary","year":"1993","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0130","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1126\/science.1145406","article-title":"Draft genome of the filarial nematode parasite Brugia malayi","volume":"317","author":"Ghedin","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0125","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijpara.2009.11.001","article-title":"Unresolved issues in anthelmintic pharmacology for helminthiases of humans","volume":"40","author":"Geary","year":"2010","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0140","doi-asserted-by":"crossref","first-page":"e22390","DOI":"10.1371\/journal.pone.0022390","article-title":"Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans","volume":"6","author":"Glendinning","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0145","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1038\/sj.bjp.0703937","article-title":"GLC-3: a novel fipronil and BIDN-sensitive, but picrotoxinin-insensitive, l-glutamate-gated chloride channel subunit from Caenorhabditis elegans","volume":"132","author":"Horoszok","year":"2001","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0150","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1056\/NEJMra064142","article-title":"Control of neglected tropical diseases","volume":"357","author":"Hotez","year":"2007","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0155","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0166-6851(99)00120-6","article-title":"Ligand-gated chloride channel subunits encoded by the Haemonchus contortus and Ascaris suum orthologues of the Caenorhabditis elegans gbr-2 (avr-14) gene","volume":"103","author":"Jagannathan","year":"1999","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0160","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.ijpara.2007.09.010","article-title":"Localization of gender-regulated gene expression in the filarial nematode Brugia malayi","volume":"38","author":"Jiang","year":"2008","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0165","first-page":"305","article-title":"How long do the effects of ivermectin on adult Onchocerca volvulus persist?","volume":"44","author":"Klager","year":"1993","journal-title":"Trop. Med. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0180","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1017\/S0022149X00011482","article-title":"Abnormal patterns of embryogenesis in Dirofilaria immitis treated with ivermectin","volume":"62","author":"Lok","year":"1988","journal-title":"J. Helminthol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0185","first-page":"235","article-title":"Studies of reproductive competence in male Dirofilaria immitis treated with milbemycin oxime","volume":"46","author":"Lok","year":"1995","journal-title":"Trop. Med. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0170","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0378-1119(97)00436-8","article-title":"Alternative splicing of a Caenorhabditis elegans gene produces two novel inhibitory amino acid receptor subunits with identical ligand binding domains but different ion channels","volume":"201","author":"Laughton","year":"1997","journal-title":"Gene"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0175","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.molbiopara.2004.07.002","article-title":"Quantitative analysis of gender-regulated transcripts in the filarial nematode Brugia malayi by real-time RT-PCR","volume":"137","author":"Li","year":"2004","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0190","doi-asserted-by":"crossref","first-page":"591","DOI":"10.4269\/ajtmh.1993.48.591","article-title":"Treatment of subperiodic Brugia malayi infection with a single dose of ivermectin","volume":"48","author":"Mak","year":"1993","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"Pt 2","key":"10.1016\/j.ijpddr.2014.01.002_b0200","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1017\/S0031182000084833","article-title":"An electrophysiological preparation of Ascaris suum pharyngeal muscle reveals a glutamate-gated chloride channel sensitive to the avermectin analogue, milbemycin D","volume":"112","author":"Martin","year":"1996","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0195","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0304-4017(97)00136-2","article-title":"Comparative efficacy of moxidectin 2% equine oral gel and ivermectin 2% equine oral paste against Onchocerca cervicalis (Railliet and Henry, 1910) microfilariae in horses with naturally acquired infections in Formosa (Argentina)","volume":"73","author":"Mancebo","year":"1997","journal-title":"Vet. Parasitol."},{"issue":"Suppl.","key":"10.1016\/j.ijpddr.2014.01.002_b0205","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.1017\/S0031182005008668","article-title":"Drug resistance and neurotransmitter receptors of nematodes: recent studies on the mode of action of levamisole","volume":"131","author":"Martin","year":"2005","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0215","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1017\/S0031182007000042","article-title":"Nematode ligand-gated chloride channels: an appraisal of their involvement in macrocyclic lactone resistance and prospects for developing molecular markers","volume":"134","author":"McCavera","year":"2007","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0210","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1124\/mol.108.053363","article-title":"An ivermectin-sensitive glutamate-gated chloride channel from the parasitic nematode Haemonchus contortus","volume":"75","author":"McCavera","year":"2009","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0220","doi-asserted-by":"crossref","first-page":"20120","DOI":"10.1073\/pnas.1011983107","article-title":"Ivermectin disrupts the function of the excretory-secretory apparatus in microfilariae of Brugia malayi","volume":"107","author":"Moreno","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0225","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1017\/S0031182004006183","article-title":"Genetic variability of glutamate-gated chloride channel genes in ivermectin-susceptible and -resistant strains of Cooperia oncophora","volume":"129","author":"Njue","year":"2004","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0230","doi-asserted-by":"crossref","first-page":"e317","DOI":"10.1371\/journal.pntd.0000317","article-title":"The global programme to eliminate lymphatic filariasis: health impact after 8 years","volume":"2","author":"Ottesen","year":"2008","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0235","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0304-4017(96)00948-X","article-title":"Efficacies of different doses of ivermectin against male, female and L4 Oesophagostomum dentatum in pigs","volume":"65","author":"Petersen","year":"1996","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0240","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1002\/cne.10735","article-title":"Distribution of glutamate-gated chloride channel subunits in the parasitic nematode Haemonchus contortus","volume":"462","author":"Portillo","year":"2003","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0245","first-page":"97","article-title":"Antifilarial activity of macrocyclic lactones: comparative studies with ivermectin, doramectin, milbemycin A4 oxime, and moxidectin in Litomosoides carinii, Acanthocheilonema viteae, Brugia malayi, and B. pahangi infection of Mastomys coucha","volume":"45","author":"Schares","year":"1994","journal-title":"Trop. Med. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0250","doi-asserted-by":"crossref","first-page":"881","DOI":"10.4269\/ajtmh.2005.73.881","article-title":"Effects of ivermectin and diethylcarbamazine on microfilariae and overall microfilaria production in bancroftian filariasis","volume":"73","author":"Stolk","year":"2005","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0255","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.molbiopara.2006.06.007","article-title":"Cloning and characterization of genes encoding alpha and beta subunits of glutamate-gated chloride channel protein in Cylicocyclus nassatus","volume":"150","author":"Tandon","year":"2006","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0260","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.exppara.2009.12.003","article-title":"Brugia malayi: in vitro effects of ivermectin and moxidectin on adults and microfilariae","volume":"124","author":"Tompkins","year":"2010","journal-title":"Exp. Parasitol."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0265","doi-asserted-by":"crossref","first-page":"33167","DOI":"10.1074\/jbc.272.52.33167","article-title":"Genetic and biochemical evidence for a novel avermectin-sensitive chloride channel in Caenorhabditis elegans. Isolation and characterization","volume":"272","author":"Vassilatis","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0270","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1007\/PL00006174","article-title":"Evolutionary relationship of the ligand-gated ion channels and the avermectin-sensitive, glutamate-gated chloride channels","volume":"44","author":"Vassilatis","year":"1997","journal-title":"J. Mol. Evol."},{"issue":"Suppl.","key":"10.1016\/j.ijpddr.2014.01.002_b0280","doi-asserted-by":"crossref","first-page":"S85","DOI":"10.1017\/S0031182005008218","article-title":"Glutamate-gated chloride channels and the mode of action of the avermectin\/milbemycin anthelmintics","volume":"131","author":"Wolstenholme","year":"2005","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpddr.2014.01.002_b0275","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s10158-007-0056-0","article-title":"The cys-loop ligand-gated ion channel gene family of Brugia malayi and Trichinella spiralis: a comparison with Caenorhabditis elegans","volume":"7","author":"Williamson","year":"2007","journal-title":"Invert. Neurosci."},{"key":"10.1016\/j.ijpddr.2014.01.002_b0285","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.exppara.2004.08.003","article-title":"Dirofilaria immitis: identification of a novel ligand-gated ion channel-related polypeptide","volume":"108","author":"Yates","year":"2004","journal-title":"Exp. Parasitol."}],"container-title":["International Journal for Parasitology: Drugs and Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211320714000037?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211320714000037?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:44:10Z","timestamp":1761921850000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211320714000037"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":57,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,8]]}},"alternative-id":["S2211320714000037"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpddr.2014.01.002","relation":{},"ISSN":["2211-3207"],"issn-type":[{"value":"2211-3207","type":"print"}],"subject":[],"published":{"date-parts":[[2014,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High level expression of a glutamate-gated chloride channel gene in reproductive tissues of Brugia malayi may explain the sterilizing effect of ivermectin on filarial worms","name":"articletitle","label":"Article Title"},{"value":"International Journal for Parasitology: Drugs and Drug Resistance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpddr.2014.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}