{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T20:25:49Z","timestamp":1783023949080,"version":"3.54.6"},"reference-count":83,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,2,28]],"date-time":"2018-02-28T00:00:00Z","timestamp":1519776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005202","name":"University of Prince Edward Island","doi-asserted-by":"publisher","award":["214602"],"award-info":[{"award-number":["214602"]}],"id":[{"id":"10.13039\/501100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005202","name":"University of Prince Edward Island","doi-asserted-by":"publisher","award":["199308"],"award-info":[{"award-number":["199308"]}],"id":[{"id":"10.13039\/501100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005202","name":"University of Prince Edward Island","doi-asserted-by":"publisher","award":["210205-70"],"award-info":[{"award-number":["210205-70"]}],"id":[{"id":"10.13039\/501100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005202","name":"University of Prince Edward Island","doi-asserted-by":"publisher","award":["PGS3"],"award-info":[{"award-number":["PGS3"]}],"id":[{"id":"10.13039\/501100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005202","name":"University of Prince Edward Island","doi-asserted-by":"publisher","award":["ACOA-AIF TREAT2"],"award-info":[{"award-number":["ACOA-AIF TREAT2"]}],"id":[{"id":"10.13039\/501100005202","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["402288-12"],"award-info":[{"award-number":["402288-12"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal for Parasitology: Drugs and Drug Resistance"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.ijpddr.2018.02.007","type":"journal-article","created":{"date-parts":[[2018,3,18]],"date-time":"2018-03-18T18:13:25Z","timestamp":1521396805000},"page":"174-188","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["High level efficacy of lufenuron against sea lice (Lepeophtheirus salmonis) linked to rapid impact on moulting processes"],"prefix":"10.1016","volume":"8","author":[{"given":"Jordan D.","family":"Poley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura M.","family":"Braden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amber M.","family":"Messmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Okechukwu O.","family":"Igboeli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shona K.","family":"Whyte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Macdonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Gameiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucien","family":"Rufener","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacques","family":"Bouvier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorota W.","family":"Wadowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben F.","family":"Koop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barry C.","family":"Hosking","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark D.","family":"Fast","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpddr.2018.02.007_bib1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.pt.2014.12.006","article-title":"Drug resistance in sea lice: a threat to salmonid aquaculture","volume":"31","author":"Aaen","year":"2015","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib2","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.ibmb.2004.03.009","article-title":"Significance of the sulfonylurea receptor (SUR) as the target of diflubenzuron in chitin synthesis inhibition in Drosophila melanogaster and Blattella germanica","volume":"34","author":"Abo-Elghar","year":"2004","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib3","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0092-8674(00)80094-X","article-title":"The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal","volume":"86","author":"Alcedo","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib4","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.ibmb.2009.02.002","article-title":"Analysis of functions of the chitin deacetylase gene family in Tribolium castaneum","volume":"39","author":"Arakane","year":"2009","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib5","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s00018-009-0161-9","article-title":"Insect chitinase and chitinase-like proteins","volume":"67","author":"Arakane","year":"2010","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib6","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3390\/ijms18010091","article-title":"The distribution of lectins across the phylum Nematoda: a genome-wide search","volume":"18","author":"Bauters","year":"2017","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0130719","article-title":"The impact of selection with diflubenzuron, a chitin synthesis inhibitor, on the fitness of two Brazilian Aedes aegypti field populations","volume":"10","author":"Belinato","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib8","doi-asserted-by":"crossref","first-page":"12807","DOI":"10.1073\/pnas.0503709102","article-title":"Cyp12a4 confers lufenuron resistance in a natural population of Drosophila melanogaster","volume":"102","author":"Bogwitz","year":"2005","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib9","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1046\/j.1365-2109.2000.00509.x","article-title":"Efficacy of teflubenzuron (Calicide\u00ae) for the treatment of sea lice, Lepeophtheirus salmonis (Kr\u00f8yer 1838), infestations of farmed Atlantic salmon (Salmo salar L.)","volume":"31","author":"Branson","year":"2000","journal-title":"Aquacult. Res."},{"issue":"1\/2","key":"10.1016\/j.ijpddr.2018.02.007_bib10","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1163\/18759866-0690102003","article-title":"Moulting in the chalimus larva of the salmon louse Lepeophtheirus salmonis (Copepoda, Caligidae)","volume":"69","author":"Bron","year":"2000","journal-title":"Contrib. Zool."},{"issue":"1\/2","key":"10.1016\/j.ijpddr.2018.02.007_bib11","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1163\/18759866-0690102004","article-title":"Ultrastructure of the cuticle of the chalimus larva of the salmon louse Lepeophtheirus salmonis (Kr\u00f8yer, 1838) (Copepoda: Caligidae)","volume":"69","author":"Bron","year":"2000","journal-title":"Contrib. Zool."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib12","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1186\/1471-2164-14-408","article-title":"Salmon lice (Lepeophtheirus salmonis) showing varying emamectin benzoate susceptibilities differ in neuronal acetylcholine receptor and GABA-gated chloride channel mRNA expression","volume":"14","author":"Carmichael","year":"2013","journal-title":"BMC Genom."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0137394","article-title":"A survey of the ATP-binding cassette (ABC) gene superfamily in the salmon louse (Lepeophtheirus salmonis)","volume":"10","author":"Carmona-Anto\u00f1anzas","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib14","first-page":"532","article-title":"A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples","volume":"15","author":"Chomczynski","year":"1993","journal-title":"Biotechnique"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib15","first-page":"942","article-title":"Modification of the TRI Reagent\u00ae DNA\/Protein isolation procedure for isolation of RNA from polysaccharide and proteoglycan-rich sources","volume":"19","author":"Chomczynski","year":"1995","journal-title":"Biotechnique"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib16","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1471-2164-9-22","article-title":"Annotation and analysis of a large cuticular protein family with the R & R Consensus in Anopheles gambiae","volume":"9","author":"Cornman","year":"2008","journal-title":"BMC Genom."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib17","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1016\/j.ijpara.2009.04.004","article-title":"Functional characterisation of the maternal yolk-associated protein (LsYAP) utilising systemic RNA interference in the salmon louse (Lepeophtheirus salmonis) (Crustacea: Copepoda)","volume":"39","author":"Dalvin","year":"2009","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib18","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1093\/jmedent\/35.5.720","article-title":"Mode of action of lufenuron on larval cat fleas (Siphonaptera: Pulicidae)","volume":"35","author":"Dean","year":"1998","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib19","doi-asserted-by":"crossref","first-page":"14692","DOI":"10.1073\/pnas.1618258113","article-title":"Resistance mutation conserved between insects and mites unravels the benzoylurea insecticide mode of action on chitin biosynthesis","volume":"113","author":"Douris","year":"2016","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib20","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1603\/0022-0493-93.6.1741","article-title":"Laboratory evaluation of lufenuron on immature stages of potato tuber moth (Lepidoptera\u202f: Gelechiidae)","volume":"93","author":"Edomwande","year":"2000","journal-title":"J. Econ. Entomol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib21","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s12864-015-1277-y","article-title":"Characterization of a novel RXR receptor in the salmon louse (Lepeophtheirus salmonis, Copepoda) regulating growth and female reproduction","volume":"16","author":"Eichner","year":"2015","journal-title":"BMC Genom."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib22","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/1471-2164-9-126","article-title":"Salmon louse (Lepeophtheirus salmonis) transcriptomes during post molting maturation and egg production, revealed using EST-sequencing and microarray analysis","volume":"15","author":"Eichner","year":"2008","journal-title":"BMC Genom."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib23","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.parint.2014.10.006","article-title":"Instar growth and molt increments in Lepeophtheirus salmonis (Copepoda: Caligidae) chalimus larvae","volume":"64","author":"Eichner","year":"2015","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib24","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.exppara.2015.01.011","article-title":"Molecular characterisation and functional analysis of LsChi2, a chitinase found in the salmon louse (Lepeophtheirus salmonis)","volume":"151\u2013152","author":"Eichner","year":"2015","journal-title":"Exp. Parasitol."},{"issue":"7","key":"10.1016\/j.ijpddr.2018.02.007_bib25","article-title":"Annual report on pesticide residues","volume":"8","author":"European Food Safety Authority","year":"2010","journal-title":"EFSA Journal"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib26","series-title":"European Public MRL Assessment Report (EPMAR) Lufenuron (Fin Fish)","author":"European Medicines Agency","year":"2015"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib27","series-title":"Freedom of Information Summary for Lufenuron Import Tolerance","author":"Food and Drug Administration (FDA)","year":"2016"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib28","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.ejcb.2008.09.002","article-title":"Effects of benzoylphenylurea on chitin synthesis and orientation in the cuticle of the Drosophila larva","volume":"88","author":"Gangishetti","year":"2009","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib29","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1469-185X.1985.tb00424.x","article-title":"Calcium balance and moulintg in the Crustacea","volume":"60","author":"Greenway","year":"1985","journal-title":"Biol. Rev."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib30","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073539","article-title":"The salmon louse Lepeophtheirus salmonis (Copepoda: Caligidae) life cycle has only two chalimus stages","volume":"8","author":"Hamre","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib31","doi-asserted-by":"crossref","first-page":"R19","DOI":"10.1186\/gb-2007-8-2-r19","article-title":"qBase relative quantification framework and software for management and automated analysis of real-time quantitative PCR data","volume":"8","author":"Hellemans","year":"2007","journal-title":"Genome Biol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/nar\/gkn923","article-title":"Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists","volume":"37","author":"Huang","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib33","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4","author":"Huang","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib34","doi-asserted-by":"crossref","first-page":"22","DOI":"10.2527\/af.2014-0004","article-title":"Lepeophtheirus salmonis: a persisting challenge for salmon aquaculture","volume":"4","author":"Igboeli","year":"2014","journal-title":"Anim. Front"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib35","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1002\/ps.3620","article-title":"Sea lice population and sex differences in P-glycoprotein expression and emamectin benzoate resistance on salmon farms in the Bay of Fundy, New Brunswick, Canada","volume":"70","author":"Igboeli","year":"2013","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib36","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1271\/bbb.65.1840","article-title":"Purification and structural determination of a phosphorylated peptide with anti-calcification and chitin-binding activities in the exoskeleton of the crayfish, Procambarus clarkii","volume":"65","author":"Inoue","year":"2001","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib37","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.cropro.2014.08.007","article-title":"Stability, cross-resistance and fitness costs of resistance to emamectin benzoate in a re-selected field population of the beet armyworm, Spodoptera exigua (Lepidoptera: Noctuidae)","volume":"65","author":"Ishtiaq","year":"2014","journal-title":"Crop Protect."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib38","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1186\/1756-0500-4-267","article-title":"GO Trimming: Systematically reducing redundancy in large Gene Ontology datasets","volume":"4","author":"Jantzen","year":"2011","journal-title":"BMC Res. Notes"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib39","first-page":"209","article-title":"Detection of emamectin benzoate tolerance emergence in different life stages of sea lice, Lepeophtheirus salmonis, on farmed Atlantic salmon","volume":"36","author":"Jones","year":"2013","journal-title":"Salmo salar L. J. Fish Dis"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib40","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1111\/j.1365-2583.2005.00592.x","article-title":"Aedes aegypti phosphohexomutases and uridine diphosphate-hexose pyrophosphorylases: comparison of primary sequences, substrate specificities and temporal transcription","volume":"14","author":"Kato","year":"2005","journal-title":"Insect Mol. Biol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib41","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.tig.2009.07.006","article-title":"More than just orphans: are taxonomically-restricted genes important in evolution?","volume":"25","author":"Khalturin","year":"2009","journal-title":"Trends Genet."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib42","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1186\/1471-2164-9-575","article-title":"Differential expression profiling of components associated with exoskeletal hardening in crustaceans","volume":"9","author":"Kuballa","year":"2008","journal-title":"BMC Genom."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib43","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1186\/1471-2164-12-147","article-title":"Moult cycle specific differential gene expression profiling of the crab Portunus pelagicus","volume":"147","author":"Kuballa","year":"2011","journal-title":"BMC Genom."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib44","doi-asserted-by":"crossref","first-page":"5257","DOI":"10.1046\/j.1432-1327.2000.01602.x","article-title":"The amino-acid sequence of the abalone (Haliotis laevigata) nacre protein perlucin: detection of a functional C-type lectin domaine with galactose\/mannose specificity","volume":"267","author":"Mann","year":"2000","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib45","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.pestbp.2010.04.013","article-title":"The effect of lufenuron, a chitin synthesis inhibitor, on oogenesis of Rhodnius prolixus","volume":"98","author":"Mansur","year":"2010","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib46","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1744-7917.2012.01535.x","article-title":"Chitin synthesis inhibitors\u202f: old molecules and new developments","volume":"20","author":"Merzendorfer","year":"2013","journal-title":"Insect Sci."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib47","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00360-005-0005-3","article-title":"Insect chitin synthases: a review","volume":"176","author":"Merzendorfer","year":"2006","journal-title":"J. Comp. Physiol. B Biochem. Syst. Environ. Physiol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib48","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.ibmb.2011.12.008","article-title":"Genomic and proteomic studies on the effects of the insect growth regulator diflubenzuron in the model beetle species Tribolium castaneum","volume":"42","author":"Merzendorfer","year":"2012","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib49","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1002\/ps.3476","article-title":"The sulfonylurea receptor Sur is dispensable for chitin synthesis in Drosophila melanogaster","volume":"69","author":"Meyer","year":"2013","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib50","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1002\/ps.1238","article-title":"Pesticide residues in beeswax samples collected from honey bee colonies (Apis mellifera L.) in France","volume":"62","author":"Mommaerts","year":"2006","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib51","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/0965-1748(94)90138-4","article-title":"Diflubenzuron affects gamma-thioGTP stimulated Ca2+ transport in vitro in intracellular vesicles from the integument of the newly molted american cockroach, Periplanet americana L","volume":"24","author":"Nakagawa","year":"1994","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib52","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1186\/s12864-015-2183-z","article-title":"Comparative transcriptome analysis of lufenuron-resistant and susceptible strains of Spodoptera frugiperda (Lepidoptera: Noctuidae)","volume":"16","author":"Nascimento","year":"2015","journal-title":"BMC Genom."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib53","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.aquatox.2015.07.008","article-title":"Transcriptional responses to teflubenzuron exposure in European lobster (Homarus gammarus)","volume":"167","author":"Olsvik","year":"2015","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib54","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cbpa.2017.01.004","article-title":"Molecular characterization and functional analysis of a salmon louse (Lepeophtheirus salmonis, Kr\u00f8yer 1838) heme peroxidase with a potential role in extracellular matrixes","volume":"206","author":"\u00d8verg\u00e5rd","year":"2017","journal-title":"Comp. Biochem. Physiol. Part A Mol. Integr. Physiol"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib55","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.cbd.2016.08.004","article-title":"Cypermethrin exposure induces metabolic and stress-related gene expression in copepodid salmon lice (Lepeophtheirus salmonis)","volume":"20","author":"Poley","year":"2016","journal-title":"Comp. Biochem. Physiol. Genom. Proteonomics"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib56","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/BF00623561","article-title":"Extraction of uranium from sea water by cultured algae","volume":"60","author":"Post","year":"1973","journal-title":"Nat. Sci."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib57","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/0048-3575(74)90072-8","article-title":"1-(2,6-disubstituted benzoyl)-3-phenylurea insecticides: inhibitors of chitin synthesis","volume":"4","author":"Post","year":"1974","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib58","first-page":"1","article-title":"Use of lumpfish for sea-lice control in salmon farming: challenges and opportunities","volume":"0","author":"Powell","year":"2017","journal-title":"Rev. Aquacult."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib59","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.devcel.2015.06.019","article-title":"Patterned anchorage to the apical extracellular matrix defines tissue shape in the developing appendages of Drosophila","volume":"34","author":"Ray","year":"2015","journal-title":"Dev. Cell"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib60","series-title":"A Language and Environment for Statistical Computing. R Found. Stat. Comput","isbn-type":"print","author":"R Core Team","year":"2016","ISBN":"https:\/\/id.crossref.org\/isbn\/3900051070"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib61","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0965-1748(96)00090-2","article-title":"Structure and spatial expression of the Manduca sexta MSCP14.6 cuticle gene","volume":"27","author":"Rebers","year":"1997","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib62","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/S0965-1748(01)00056-X","article-title":"A conserved domain in arthropod cuticular proteins binds chitin","volume":"31","author":"Rebers","year":"2001","journal-title":"Insect Biochem. Mol. Biol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib63","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3354\/dao051101","article-title":"Clinical efficacy of teflubenzuron (Calicide\u00ae) for the treatment of Lepeophtheirus salmonis infestations of farmed Atlantic salmon Salmo salar at low water temperatures","volume":"51","author":"Ritchie","year":"2002","journal-title":"Dis. Aquat. Org."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib64","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1603\/0022-2585-39.6.882","article-title":"Cross-resistance to pyrethroid and organophosphorus insecticides induced by selection with temephos in Aedes aegypti (Diptera: Culicidae) from Cuba","volume":"39","author":"Rodriguez","year":"2002","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib65","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/jfd.12018","article-title":"Use of Atlantic salmon, Salmo salar L., farm treatment data and bioassays to assess for resistance of sea lice, Lepeophtheirus salmonis, to emamectin benzoate (SLICE\u00ae) in British Columbia, Canada","volume":"36","author":"Saksida","year":"2013","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib66","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.molbiopara.2016.06.007","article-title":"The ecdysone receptor (EcR) is a major regulator of tissue development and growth in the marine salmonid ectoparasite, Lepeophtheirus salmonis (Copepoda, Caligidae)","volume":"208","author":"Sandlund","year":"2016","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib67","series-title":"Review and Synthesis of the Environmental Impacts of Aquaculture","author":"Scottish Executive","year":"2002"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib68","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/1471-2199-10-44","article-title":"A trypsin-like protease with apparent dual function in early Lepeophtheirus salmonis (Kr\u00f8yer) development","volume":"10","author":"Skern-mauritzen","year":"2009","journal-title":"BMC Mol. Biol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib69","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.pestbp.2014.11.014","article-title":"IRAC\u202f: mode of action classification and insecticide resistance management","volume":"121","author":"Sparks","year":"2015","journal-title":"Pestic. Biochem. Physiol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib70","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.aquaculture.2016.02.014","article-title":"\u2018Snorkel\u2019 sea lice barrier technology reduces sea lice loads on harvest-sized Atlantic salmon with minimal welfare impacts","volume":"458","author":"Stien","year":"2016","journal-title":"Aquaculture"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib71","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1046\/j.1365-2761.1999.00176.x","article-title":"The efficacy of emamectin benzoate as an oral treatment of sea lice, Lepeophtheirus salmonis (Kr\u00f8yer), infestations in Atlantic salmon, Salmo salar L","volume":"22","author":"Stone","year":"1999","journal-title":"J. Fish. Dis."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib72","doi-asserted-by":"crossref","first-page":"45219","DOI":"10.1074\/jbc.M408840200","article-title":"Characteristic recognition of N-acetylgalactosamine by an invertebrate C-type lectin, CEL-I, revealed by x-ray crystallographic analysis","volume":"279","author":"Sugawara","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib73","doi-asserted-by":"crossref","first-page":"6847","DOI":"10.1021\/acs.jafc.5b02460","article-title":"Benzoylurea chitin synthesis inhibitors","volume":"63","author":"Sun","year":"2015","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib74","doi-asserted-by":"crossref","first-page":"6000","DOI":"10.1111\/mec.12072","article-title":"Transcriptomics of coping strategies in free-swimming Lepeophtheirus salmonis (Copepoda) larvae responding to abiotic stress","volume":"21","author":"Sutherland","year":"2012","journal-title":"Mol. Ecol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib75","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/eva.12237","article-title":"Transcriptomic responses to emamectin benzoate in Pacific and Atlantic Canada salmon lice Lepeophtheirus salmonis with differing levels of drug resistance","volume":"8","author":"Sutherland","year":"2015","journal-title":"Evol. Appl."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib76","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.coi.2005.11.014","article-title":"The mannose-binding lectin: a prototypic pattern recognition molecule","volume":"18","author":"Takahashi","year":"2006","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib77","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2002-3-7-research0034","article-title":"Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes","volume":"3","author":"Vandesompele","year":"2002","journal-title":"Genome Biol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib78","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1006\/bbrc.1999.1907","article-title":"Purification and characterization of perlucin and perlustrin, two new proteins from the shell of the mollusc Haliotis laevigata","volume":"267","author":"Weiss","year":"2000","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib79","series-title":"Diflubenzuron in Drinking Water Use for Vector Control in Drinking Water Sources and Containers","author":"World Health Organization","year":"2008"},{"key":"10.1016\/j.ijpddr.2018.02.007_bib80","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/(SICI)1097-010X(19970501)278:1<37::AID-JEZ4>3.0.CO;2-7","article-title":"Lufenuron, a chitin-synthesis inhibitor, interrupts development of Drosophila melanogaster","volume":"278","author":"Wilson","year":"1997","journal-title":"J. Exp. Zool."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib81","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1007\/s10126-011-9398-z","article-title":"Genomic resources for sea lice: analysis of ESTs and mitochondrial genomes","volume":"14","author":"Yasuike","year":"2012","journal-title":"Mar. Biotechnol."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib82","doi-asserted-by":"crossref","first-page":"24352","DOI":"10.1074\/jbc.M116.720581","article-title":"Helicoidal organization of chitin in the cuticle of the migratory locust requires the function of the chitin deacetylase 2 enzyme (LmCDA2)","volume":"291","author":"Yu","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.ijpddr.2018.02.007_bib83","doi-asserted-by":"crossref","first-page":"6650","DOI":"10.1073\/pnas.0800739105","article-title":"Functional specialization among insect chitinase family genes revealed by RNA interference","volume":"105","author":"Zhu","year":"2008","journal-title":"Proc. Natl. Acad. Sci. Unit. States Am."}],"container-title":["International Journal for Parasitology: Drugs and Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211320717301215?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211320717301215?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:47:46Z","timestamp":1761922066000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211320717301215"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":83,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["S2211320717301215"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpddr.2018.02.007","relation":{},"ISSN":["2211-3207"],"issn-type":[{"value":"2211-3207","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"High level efficacy of lufenuron against sea lice (Lepeophtheirus salmonis) linked to rapid impact on moulting processes","name":"articletitle","label":"Article Title"},{"value":"International Journal for Parasitology: Drugs and Drug Resistance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpddr.2018.02.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier Ltd on behalf of Australian Society for Parasitology.","name":"copyright","label":"Copyright"}]}}