{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T00:19:20Z","timestamp":1790900360628,"version":"4.1.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,5,13]],"date-time":"2018-05-13T00:00:00Z","timestamp":1526169600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AI128940"],"award-info":[{"award-number":["R01 AI128940"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U19 AI089672"],"award-info":[{"award-number":["U19 AI089672"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["2014FB005"],"award-info":[{"award-number":["2014FB005"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["2017FE468-185"],"award-info":[{"award-number":["2017FE468-185"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31260508"],"award-info":[{"award-number":["31260508"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81761128017"],"award-info":[{"award-number":["81761128017"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010025","name":"Bairen Program of Yunnan Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal for Parasitology: Drugs and Drug Resistance"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.ijpddr.2018.05.003","type":"journal-article","created":{"date-parts":[[2018,5,21]],"date-time":"2018-05-21T22:24:48Z","timestamp":1526941488000},"page":"320-328","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Longitudinal surveillance of drug resistance in Plasmodium falciparum isolates from the China-Myanmar border reveals persistent circulation of multidrug resistant parasites"],"prefix":"10.1016","volume":"8","author":[{"given":"Yao","family":"Bai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaqi","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinting","family":"Geng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiling","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weilin","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zenglei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huguette Gaelle","family":"Ngassa Mbenda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanrui","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuiying","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huae","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonghua","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaming","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoqing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liwang","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpddr.2018.05.003_bib1","doi-asserted-by":"crossref","first-page":"641","DOI":"10.4269\/ajtmh.2007.76.641","article-title":"Pfmdr1 and in vivo resistance to artesunate-mefloquine in falciparum malaria on the Cambodian-Thai border","volume":"76","author":"Alker","year":"2007","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib2","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/S1473-3099(16)30409-1","article-title":"Genetic markers associated with dihydroartemisinin-piperaquine failure in Plasmodium falciparum malaria in Cambodia: a genotype-phenotype association study","volume":"17","author":"Amato","year":"2017","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib3","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/nature12876","article-title":"A molecular marker of artemisinin-resistant Plasmodium falciparum malaria","volume":"505","author":"Ariey","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.ijpddr.2018.05.003_bib4","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/jac\/dkg294","article-title":"DHFR and DHPS genotypes of Plasmodium falciparum isolates from Gabon correlate with in vitro activity of pyrimethamine and cycloguanil, but not with sulfadoxine-pyrimethamine treatment efficacy","volume":"52","author":"Aubouy","year":"2003","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib5","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.molbiopara.2007.01.018","article-title":"Plasmodium falciparum Na+\/H+ exchanger activity and quinine resistance","volume":"153","author":"Bennett","year":"2007","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib6","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.actatropica.2009.10.016","article-title":"Monitoring of in vitro susceptibilities and molecular markers of resistance of Plasmodium falciparum isolates from Thai-Myanmar border to chloroquine, quinine, mefloquine and artesunate","volume":"113","author":"Chaijaroenkul","year":"2010","journal-title":"Acta Trop."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib7","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.actatropica.2011.02.016","article-title":"Malaria in the greater Mekong subregion: heterogeneity and complexity","volume":"121","author":"Cui","year":"2012","journal-title":"Acta Trop."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib8","first-page":"674","article-title":"Malaria trends and challenges in the greater Mekong subregion","volume":"40","author":"Delacollette","year":"2009","journal-title":"Southeast Asian J. Trop Med. Publ. Health"},{"key":"10.1016\/j.ijpddr.2018.05.003_bib9","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1128\/AAC.50.5.1893-1895.2006","article-title":"Selection of Plasmodium falciparum pfmdr1 alleles following therapy with artemether-lumefantrine in an area of Uganda where malaria is highly endemic","volume":"50","author":"Dokomajilar","year":"2006","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib10","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1056\/NEJMoa0808859","article-title":"Artemisinin resistance in Plasmodium falciparum malaria","volume":"361","author":"Dondorp","year":"2009","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib11","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1186\/s12916-015-0539-5","article-title":"Plasmodium falciparum dihydroartemisinin-piperaquine failures in Cambodia are associated with mutant K13 parasites presenting high survival rates in novel piperaquine in vitro assays: retrospective and prospective investigations","volume":"13","author":"Duru","year":"2015","journal-title":"BMC Med."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib12","doi-asserted-by":"crossref","first-page":"3908","DOI":"10.1128\/AAC.01793-10","article-title":"Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites","volume":"55","author":"Eastman","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib13","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.mib.2007.07.007","article-title":"Advances in understanding the genetic basis of antimalarial drug resistance","volume":"10","author":"Ekland","year":"2007","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib14","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.EI10-0013-2016","article-title":"Artemisinin-resistant plasmodium falciparum malaria","volume":"4","author":"Fairhurst","year":"2016","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib15","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1111\/j.1365-2958.2004.04035.x","article-title":"Dissecting the loci of low-level quinine resistance in malaria parasites","volume":"52","author":"Ferdig","year":"2004","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib16","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/S1097-2765(05)00077-8","article-title":"Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance","volume":"6","author":"Fidock","year":"2000","journal-title":"Mol Cell"},{"key":"10.1016\/j.ijpddr.2018.05.003_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005976","article-title":"Evolution of Fitness Cost-Neutral Mutant PfCRT Conferring P. falciparum 4-aminoquinoline drug resistance is accompanied by altered parasite metabolism and digestive vacuole physiology","volume":"12","author":"Gabryszewski","year":"2016","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib18","first-page":"602","article-title":"Randomised comparison on the treatment of falciparum malaria with dihydroartemisinin and piperaquine","volume":"73","author":"Gao","year":"1993","journal-title":"Natl. Med. J. Chin."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib19","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1038\/nbt.2925","article-title":"Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system","volume":"32","author":"Ghorbal","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib20","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1124\/pr.57.1.4","article-title":"Mechanisms of resistance of malaria parasites to antifolates","volume":"57","author":"Gregson","year":"2005","journal-title":"Pharmacol. Rev."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib21","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1093\/jac\/dku125","article-title":"Plasmodium falciparum multidrug resistance protein 1 (pfmrp1) gene and its association with in vitro drug susceptibility of parasite isolates from north-east Myanmar","volume":"69","author":"Gupta","year":"2014","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib22","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1128\/AAC.02306-12","article-title":"In vitro sensitivities of Plasmodium falciparum isolates from the China-Myanmar border to piperaquine and association with polymorphisms in candidate genes","volume":"57","author":"Hao","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib23","doi-asserted-by":"crossref","first-page":"1926","DOI":"10.1128\/AAC.01243-08","article-title":"Plasmodium falciparum Na+\/H+ exchanger 1 transporter is involved in reduced susceptibility to quinine","volume":"53","author":"Henry","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib24","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1093\/infdis\/jiv249","article-title":"A single mutation in K13 Predominates in southern China and is associated with delayed clearance of plasmodium falciparum following artemisinin treatment","volume":"212","author":"Huang","year":"2015","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib25","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1086\/375419","article-title":"Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi","volume":"187","author":"Kublin","year":"2003","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib26","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1093\/molbev\/msw054","article-title":"MEGA7: molecular evolutionary genetics analysis version 7.0 for bigger datasets","volume":"33","author":"Kumar","year":"2016","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib27","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1086\/655659","article-title":"Return of chloroquine-susceptible falciparum malaria in Malawi was a reexpansion of diverse susceptible parasites","volume":"202","author":"Laufer","year":"2010","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib28","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1475-2875-8-11","article-title":"Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia","volume":"8","author":"Lim","year":"2009","journal-title":"Malar. J."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib29","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1186\/s12936-015-0584-8","article-title":"In vivo monitoring of dihydroartemisinin-piperaquine sensitivity in Plasmodium falciparum along the China-Myanmar border of Yunnan Province, China from 2007 to 2013","volume":"14","author":"Liu","year":"2015","journal-title":"Malar. J."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib30","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.meegid.2015.05.002","article-title":"Molecular inference of sources and spreading patterns of Plasmodium falciparum malaria parasites in internally displaced persons settlements in Myanmar-China border area","volume":"33","author":"Lo","year":"2015","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib31","doi-asserted-by":"crossref","first-page":"4306","DOI":"10.1128\/AAC.00321-10","article-title":"In vitro sensitivity of Plasmodium falciparum clinical isolates from the China-Myanmar border area to quinine and association with polymorphism in the Na+\/H+ exchanger","volume":"54","author":"Meng","year":"2010","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib32","doi-asserted-by":"crossref","first-page":"5069","DOI":"10.1128\/AAC.00638-09","article-title":"In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1","volume":"53","author":"Mwai","year":"2009","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib33","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.4269\/ajtmh.2007.76.1107","article-title":"In vitro antimalarial susceptibility profile and prcrt\/pfmdr-1 genotypes of Plasmodium falciparum field isolates from Malawi","volume":"76","author":"Nkhoma","year":"2007","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib34","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1056\/NEJMc0805011","article-title":"Evidence of artemisinin-resistant malaria in western Cambodia","volume":"359","author":"Noedl","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib35","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12936-015-0586-6","article-title":"Multinormal in vitro distribution of Plasmodium falciparum susceptibility to piperaquine and pyronaridine","volume":"14","author":"Pascual","year":"2015","journal-title":"Malar. J."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib36","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1093\/jac\/42.3.333","article-title":"In-vitro activity of pyronaridine and amodiaquine against African isolates (Senegal) of Plasmodium falciparum in comparison with standard antimalarial agents","volume":"42","author":"Pradines","year":"1998","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib37","doi-asserted-by":"crossref","first-page":"2943","DOI":"10.1128\/AAC.43.12.2943","article-title":"The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand","volume":"43","author":"Price","year":"1999","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib38","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/S0140-6736(04)16767-6","article-title":"Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number","volume":"364","author":"Price","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.ijpddr.2018.05.003_bib39","doi-asserted-by":"crossref","first-page":"254","DOI":"10.4269\/ajtmh.1996.55.254","article-title":"In vitro activity of antimalarials against clinical isolates of Plasmodium falciparum in Yaounde, Cameroon","volume":"55","author":"Ringwald","year":"1996","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib40","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1056\/NEJMc1403007","article-title":"Dihydroartemisinin-piperaquine failure in Cambodia","volume":"371","author":"Saunders","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib41","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1086\/507115","article-title":"Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin","volume":"194","author":"Sidhu","year":"2006","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib42","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1128\/AAC.48.5.1803-1806.2004","article-title":"Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening","volume":"48","author":"Smilkstein","year":"2004","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib43","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S1473-3099(15)70049-6","article-title":"Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: an observational cohort study","volume":"15","author":"Spring","year":"2015","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib44","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1126\/science.1260867","article-title":"Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates","volume":"347","author":"Straimer","year":"2015","journal-title":"Science"},{"key":"10.1016\/j.ijpddr.2018.05.003_bib45","doi-asserted-by":"crossref","first-page":"e0126943","DOI":"10.1371\/journal.pone.0126943","article-title":"Declining trend of Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant alleles after the withdrawal of Sulfadoxine-Pyrimethamine in North Western Ethiopia","volume":"10","author":"Tessema","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpddr.2018.05.003_bib46","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/S1473-3099(15)70032-0","article-title":"Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker","volume":"15","author":"Tun","year":"2015","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib47","doi-asserted-by":"crossref","first-page":"577","DOI":"10.4269\/ajtmh.15-0029","article-title":"Clinical efficacy of dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria at the China-Myanmar border","volume":"93","author":"Wang","year":"2015","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib48","article-title":"Genome-wide association analysis identifies genetic loci associated with resistance to multiple antimalarials in Plasmodium falciparum from China-Myanmar border","volume":"6","author":"Wang","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib49","doi-asserted-by":"crossref","first-page":"e30927","DOI":"10.1371\/journal.pone.0030927","article-title":"In vitro sensitivity of Plasmodium falciparum from China-Myanmar border area to major ACT drugs and polymorphisms in potential target genes","volume":"7","author":"Wang","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpddr.2018.05.003_bib50","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1186\/s12936-015-0672-9","article-title":"Prevalence of K13-propeller polymorphisms in Plasmodium falciparum from China-Myanmar border in 2007-2012","volume":"14","author":"Wang","year":"2015","journal-title":"Malar. J."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib51","doi-asserted-by":"crossref","first-page":"6952","DOI":"10.1128\/AAC.01255-15","article-title":"Artemisinin resistance at the China-Myanmar border and association with mutations in the K13 propeller gene","volume":"59","author":"Wang","year":"2015","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib52","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1086\/322858","article-title":"Chloroquine-resistant malaria","volume":"184","author":"Wellems","year":"2001","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib53","series-title":"World Malaria Report 2017","author":"WHO","year":"2017"},{"key":"10.1016\/j.ijpddr.2018.05.003_bib54","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1016\/S1473-3099(13)70252-4","article-title":"Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies","volume":"13","author":"Witkowski","year":"2013","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib55","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S1473-3099(16)30415-7","article-title":"A surrogate marker of piperaquine-resistant Plasmodium falciparum malaria: a phenotype-genotype association study","volume":"17","author":"Witkowski","year":"2017","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib56","doi-asserted-by":"crossref","first-page":"716","DOI":"10.3201\/eid1405.071601","article-title":"Declining artesunate-mefloquine efficacy against falciparum malaria on the Cambodia-Thailand border","volume":"14","author":"Wongsrichanalai","year":"2008","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib57","first-page":"43","article-title":"Assay of sensitivity of Plasmodium falciparum to chloroquine, amodiaquine, piperaquine, mefloquine and quinine in Yunnan province","volume":"17","author":"Yang","year":"1999","journal-title":"Chin. J. Parasitol. Parasitic. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib58","doi-asserted-by":"crossref","first-page":"498","DOI":"10.3201\/eid1703.100870","article-title":"Multidrug-resistant genotypes of Plasmodium falciparum","volume":"17","author":"Yang","year":"2011","journal-title":"Myanmar. Emerg. Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib59","doi-asserted-by":"crossref","first-page":"20100","DOI":"10.1038\/srep20100","article-title":"Distinctive origin of artemisinin-resistant Plasmodium falciparum on the China-Myanmar border","volume":"6","author":"Ye","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib60","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.actatropica.2012.09.008","article-title":"Plasmodium falciparum populations from northeastern Myanmar display high levels of genetic diversity at multiple antigenic loci","volume":"125","author":"Yuan","year":"2013","journal-title":"Acta Trop."},{"key":"10.1016\/j.ijpddr.2018.05.003_bib61","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01689-16","article-title":"Significant divergence in sensitivity to antimalarial drugs between neighboring Plasmodium falciparum populations along the eastern border of Myanmar","volume":"61","author":"Zeng","year":"2017","journal-title":"Antimicrob. Agents Chemother."}],"container-title":["International Journal for Parasitology: Drugs and Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211320718300502?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211320718300502?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:48:08Z","timestamp":1761922088000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211320718300502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["S2211320718300502"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpddr.2018.05.003","relation":{},"ISSN":["2211-3207"],"issn-type":[{"value":"2211-3207","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Longitudinal surveillance of drug resistance in Plasmodium falciparum isolates from the China-Myanmar border reveals persistent circulation of multidrug resistant parasites","name":"articletitle","label":"Article Title"},{"value":"International Journal for Parasitology: Drugs and Drug Resistance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpddr.2018.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier Ltd on behalf of Australian Society for Parasitology.","name":"copyright","label":"Copyright"}]}}