{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T21:44:50Z","timestamp":1793223890054,"version":"4.5.0"},"reference-count":80,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,12,29]],"date-time":"2018-12-29T00:00:00Z","timestamp":1546041600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011134","name":"Rhode Island Agricultural Experiment Station","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011134","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004564","name":"Ministarstvo Prosvete, Nauke i Tehnolo\u0161kog Razvoja","doi-asserted-by":"publisher","award":["TR31087"],"award-info":[{"award-number":["TR31087"]}],"id":[{"id":"10.13039\/501100004564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI047194-17"],"award-info":[{"award-number":["R01AI047194-17"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R21AI121831-01"],"award-info":[{"award-number":["R21AI121831-01"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009774","name":"College of Veterinary Medicine, University of Tennessee","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009774","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal for Parasitology: Drugs and Drug Resistance"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.ijpddr.2018.12.005","type":"journal-article","created":{"date-parts":[[2018,12,29]],"date-time":"2018-12-29T20:54:06Z","timestamp":1546116846000},"page":"44-53","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Menthol acts as a positive allosteric modulator on nematode levamisole sensitive nicotinic acetylcholine receptors"],"prefix":"10.1016","volume":"9","author":[{"given":"Shivani","family":"Choudhary","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djordje S.","family":"Marjianovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin R.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Abongwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel R.","family":"Coats","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sa\u0161a M.","family":"Trailovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard J.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan P.","family":"Robertson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijpddr.2018.12.005_bib1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s10158-016-0193-4","article-title":"The cholinomimetic morantel as an open channel blocker of the Ascaris suum ACR-16 nAChR","volume":"16","author":"Abongwa","year":"2016","journal-title":"Invertebr. Neurosci."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib2","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1111\/bph.13524","article-title":"Pharmacological profile of Ascaris suum ACR-16, a new homomeric nicotinic acetylcholine receptor widely distributed in Ascaris tissues","volume":"173","author":"Abongwa","year":"2016","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib3","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1515\/acve-2017-0013","article-title":"A brief review on the mode of action of antinematodal drugs","volume":"67","author":"Abongwa","year":"2017","journal-title":"Acta Vet. (Beogr)"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib4","first-page":"343","article-title":"Efficacy of mebendazole and levamisole alone or in combination against intestinal nematode infections after repeated targeted mebendazole treatment in Zanzibar","volume":"81","author":"Albonico","year":"2003","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib5","doi-asserted-by":"crossref","first-page":"e732","DOI":"10.1016\/j.ijid.2009.11.036","article-title":"The global war against intestinal parasites--should we use a holistic approach?","volume":"14","author":"Alum","year":"2010","journal-title":"Int. J. Infect. Dis."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib6","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1177\/009286151104500102","article-title":"The legal and regulatory framework of herbal medicinal products in the European Union: a focus on the traditional herbal medicines category","volume":"45","author":"Anquez-Traxler","year":"2011","journal-title":"Drug Inf. J."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib7","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0067674","article-title":"Menthol binding and inhibition of alpha7-nicotinic acetylcholine receptors","volume":"8","author":"Ashoor","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib8","series-title":"Plants, People, and Culture: the Science of Ethnobotany\/Michael J. Balick, Paul Alan Cox (Scientific American Library Series No. 60)","author":"Balick","year":"1996"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib9","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.lfs.2005.09.012","article-title":"Drug discovery from medicinal plants","volume":"78","author":"Balunas","year":"2005","journal-title":"Life Sci."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib10","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/S0140-6736(06)68653-4","article-title":"Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm","volume":"367","author":"Bethony","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib11","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1016\/j.tiv.2007.11.023","article-title":"Influence of carvacrol on proliferation and survival of porcine lymphocytes and intestinal epithelial cells in vitro","volume":"22","author":"Bimczok","year":"2008","journal-title":"Toxicol. Vitro"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib12","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0378-8741(03)00275-7","article-title":"Chemical composition and antifungal activity of essential oils of seven Moroccan Labiatae against Botrytis cinerea Pers: Fr","volume":"89","author":"Bouchra","year":"2003","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib13","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1021\/jf960417h","article-title":"Monoterpenes in the aromas of fresh wild mushrooms (basidiomycetes)","volume":"45","author":"Breheret","year":"1997","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib14","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/j.ijpara.2010.04.004","article-title":"Estimating the global distribution and disease burden of intestinal nematode infections: adding up the numbers--a review","volume":"40","author":"Brooker","year":"2010","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib15","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0065-308X(05)62007-6","article-title":"Global epidemiology, ecology and control of soil-transmitted helminth infections","volume":"62","author":"Brooker","year":"2006","journal-title":"Adv. Parasitol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib16","doi-asserted-by":"crossref","first-page":"2141","DOI":"10.1021\/np040106y","article-title":"The role of natural product chemistry in drug discovery","volume":"67","author":"Butler","year":"2004","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib17","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003870","article-title":"Investigation of acetylcholine receptor diversity in a nematode parasite leads to characterization of tribendimidine- and derquantel-sensitive nAChRs","volume":"10","author":"Buxton","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib18","doi-asserted-by":"crossref","first-page":"428","DOI":"10.2165\/00002018-200831050-00009","article-title":"European legislation on herbal medicines: a look into the future","volume":"31","author":"Calapai","year":"2008","journal-title":"Drug Saf."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib19","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.vetpar.2007.06.012","article-title":"Anthelmintic activity of Croton zehntneri and Lippia sidoides essential oils","volume":"148","author":"Camurca-Vasconcelos","year":"2007","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib20","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.vetpar.2008.11.009","article-title":"Acaricidal effects of the essential oil of Origanum minutiflorum (Lamiaceae) against Rhipicephalus turanicus (Acari: ixodidae)","volume":"160","author":"Cetin","year":"2009","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib21","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.bcp.2015.07.028","article-title":"Allosteric modulation of nicotinic acetylcholine receptors","volume":"97","author":"Chatzidaki","year":"2015","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib22","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/0031-9384(94)90338-7","article-title":"Sensory irritation and coolness produced by menthol: evidence for selective desensitization of irritation","volume":"56","author":"Cliff","year":"1994","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib23","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1146\/annurev.en.39.010194.002421","article-title":"Risks from natural versus synthetic insecticides","volume":"39","author":"Coats","year":"1994","journal-title":"Annu. Rev. Entomol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib24","series-title":"Complementary and Alternative Medicine in the United States","article-title":"Board on health promotion, and disease prevention, Institute of medicine","author":"Committee on the Use of Complementary and Alternative Medicine by the American Public","year":"2005"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib25","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s00436-008-0956-x","article-title":"Acaricidal efficacy of Origanum onites L. essential oil against Rhipicephalus turanicus (Ixodidae)","volume":"103","author":"Coskun","year":"2008","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib26","doi-asserted-by":"crossref","first-page":"25","DOI":"10.4269\/ajtmh.1997.57.25","article-title":"Failure of mebendazole in treatment of human hookworm infections in the southern region of Mali","volume":"57","author":"De Clercq","year":"1997","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib27","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.fitote.2004.05.002","article-title":"Constituents of aromatic plants: carvacrol","volume":"75","author":"De Vincenzi","year":"2004","journal-title":"Fitoterapia"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib28","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3390\/metabo2020303","article-title":"A historical overview of natural products in drug discovery","volume":"2","author":"Dias","year":"2012","journal-title":"Metabolites"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib29","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1111\/j.2042-7158.1994.tb03871.x","article-title":"Menthol and related cooling compounds","volume":"46","author":"Eccles","year":"1994","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib30","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/arch.20076","article-title":"Molecular and pharmacological analysis of an octopamine receptor from American cockroach and fruit fly in response to plant essential oils","volume":"59","author":"Enan","year":"2005","journal-title":"Arch. Insect Biochem. Physiol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib31","doi-asserted-by":"crossref","first-page":"124","DOI":"10.2174\/138955713804484686","article-title":"Menthol--pharmacology of an important naturally medicinal \"cool","volume":"13","author":"Farco","year":"2013","journal-title":"Mini Rev. Med. Chem."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib32","series-title":"The Rural School and Hookworm Disease","first-page":"3","author":"Ferrell","year":"1914"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib33","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0001-706X(03)00063-9","article-title":"Could control of soil-transmitted helminthic infection influence the HIV\/AIDS pandemic","volume":"86","author":"Fincham","year":"2003","journal-title":"Acta Trop."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib34","doi-asserted-by":"crossref","first-page":"732","DOI":"10.4269\/ajtmh.2007.76.732","article-title":"Low efficacy of mebendazole against hookworm in Vietnam: two randomized controlled trials","volume":"76","author":"Flohr","year":"2007","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib35","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1093\/chemse\/bjr128","article-title":"Menthol suppresses nicotinic acetylcholine receptor functioning in sensory neurons via allosteric modulation","volume":"37","author":"Hans","year":"2012","journal-title":"Chem. Senses"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib36","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/nrd4510","article-title":"The re-emergence of natural products for drug discovery in the genomics era","volume":"14","author":"Harvey","year":"2015","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib37","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.jep.2004.02.012","article-title":"Galanthamine from snowdrop--the development of a modern drug against Alzheimer's disease from local Caucasian knowledge","volume":"92","author":"Heinrich","year":"2004","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib38","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1172\/JCI34261","article-title":"Helminth infections: the great neglected tropical diseases","volume":"118","author":"Hotez","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib39","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1002\/ps.1555","article-title":"Evaluation of the environmental fate of thymol and phenethyl propionate in the laboratory","volume":"64","author":"Hu","year":"2008","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib40","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1186\/s12906-016-1408-2","article-title":"Chemical composition, anthelmintic, antibacterial and antioxidant effects of Thymus bovei essential oil","volume":"16","author":"Jaradat","year":"2016","journal-title":"BMC Complement Altern. Med."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib41","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1002\/ejp.840","article-title":"Involvement of transient receptor potential A1 channel in algesic and analgesic actions of the organic compound limonene","volume":"20","author":"Kaimoto","year":"2016","journal-title":"Eur. J. Pain"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib42","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.actatropica.2014.06.008","article-title":"Antiparasitic efficacy of a novel plant-based functional food using an Ascaris suum model in pigs","volume":"139","author":"Kaplan","year":"2014","journal-title":"Acta Trop."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib43","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.vetpar.2011.07.001","article-title":"Anthelmintic activity of Cymbopogon martinii, Cymbopogon schoenanthus and Mentha piperita essential oils evaluated in four different in vitro tests","volume":"183","author":"Katiki","year":"2011","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib44","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1080\/10937404.2013.769418","article-title":"Safety evaluation and risk assessment of d-Limonene","volume":"16","author":"Kim","year":"2013","journal-title":"J. Toxicol. Environ. Health B Crit. Rev."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib45","doi-asserted-by":"crossref","first-page":"173","DOI":"10.2307\/3271811","article-title":"The chemotherapy of helminth infestations","volume":"18","author":"Lamson","year":"1932","journal-title":"J. Parasitol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib46","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.trstmh.2003.10.009","article-title":"Severe malaria attack is associated with high prevalence of Ascaris lumbricoides infection among children in rural Senegal","volume":"98","author":"Le Hesran","year":"2004","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib47","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.bcp.2009.11.002","article-title":"Nematicidal activity of two monoterpenoids and SER-2 tyramine receptor of Caenorhabditis elegans","volume":"79","author":"Lei","year":"2010","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib48","doi-asserted-by":"crossref","first-page":"1285","DOI":"10.1590\/0001-3765201820170847","article-title":"Chemical composition and antibacterial activity of essential oils from Citrus aurantifolia leaves and fruit peel against oral pathogenic bacteria","volume":"90","author":"Lemes","year":"2018","journal-title":"An. Acad. Bras. Cienc."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib49","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1021\/jf010924l","article-title":"Volatile components of peel and leaf oils of lemon and lime species","volume":"50","author":"Lota","year":"2002","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib50","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.ejphar.2016.02.004","article-title":"Inhibition of human alpha7 nicotinic acetylcholine receptors by cyclic monoterpene carveol","volume":"776","author":"Lozon","year":"2016","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib51","doi-asserted-by":"crossref","first-page":"62","DOI":"10.4322\/rbpv.01803011","article-title":"Ovicidal and larvicidal activity in vitro of Eucalyptus globulus essential oils on Haemonchus contortus","volume":"18","author":"Macedo","year":"2009","journal-title":"Rev. Bras. Parasitol. Vet."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib52","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S1090-0233(05)80005-X","article-title":"Modes of action of anthelmintic drugs","volume":"154","author":"Martin","year":"1997","journal-title":"Vet. J."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib53","doi-asserted-by":"crossref","first-page":"484","DOI":"10.3390\/agriculture3030484","article-title":"Global change and helminth infections in grazing ruminants in europe: impacts, trends and sustainable solutions","volume":"3","author":"Morgan","year":"2013","journal-title":"Agriculture"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib54","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1021\/acs.jnatprod.5b01055","article-title":"Natural products as sources of new drugs from 1981 to 2014","volume":"79","author":"Newman","year":"2016","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib55","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1039\/a902202c","article-title":"The influence of natural products upon drug discovery","volume":"17","author":"Newman","year":"2000","journal-title":"Nat. Prod. Rep."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib56","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1093\/jmedent\/42.3.352","article-title":"Use of novel compounds for pest control: insecticidal and acaricidal activity of essential oil components from heartwood of Alaska yellow cedar","volume":"42","author":"Panella","year":"2005","journal-title":"J. Med. Entomol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib57","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0006-2952(02)01444-2","article-title":"Inhibition of acetylcholine-mediated effects by borneol","volume":"65","author":"Park","year":"2003","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib58","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0006-2952(01)00547-0","article-title":"Noncompetitive inhibition by camphor of nicotinic acetylcholine receptors","volume":"61","author":"Park","year":"2001","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib59","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0304-4017(02)00253-4","article-title":"Anthelmintic activity of essential oil of Ocimum gratissimum Linn. and eugenol against Haemonchus contortus","volume":"109","author":"Pessoa","year":"2002","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib60","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4103\/0973-7847.95849","article-title":"Historical review of medicinal plants' usage","volume":"6","author":"Petrovska","year":"2012","journal-title":"Phcog. Rev."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib61","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1111\/j.1468-1331.2004.00885.x","article-title":"Long-term efficacy and safety of galantamine in patients with mild-to-moderate Alzheimer's disease: multicenter trial","volume":"11","author":"Pirttila","year":"2004","journal-title":"Eur. J. Neurol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib62","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/10412905.1997.9699468","article-title":"Volatile composition of fourteen species of fresh wild mushrooms ( boletales )","volume":"9","author":"Rapior","year":"1997","journal-title":"J. Essent. Oil Res."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib63","doi-asserted-by":"crossref","first-page":"3419","DOI":"10.2174\/1381612043383070","article-title":"Can an apple a day keep the doctor away?","volume":"10","author":"Raskin","year":"2004","journal-title":"Curr. Pharmaceut. Des."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib64","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s10158-007-0059-x","article-title":"Ion-channels on parasite muscle: pharmacology and physiology","volume":"7","author":"Robertson","year":"2007","journal-title":"Invertebr. Neurosci."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib65","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1016\/j.tiv.2006.09.012","article-title":"Effect of different plant extracts and natural substances (PENS) against membrane damage induced by enterotoxigenic Escherichia coli K88 in pig intestinal cells","volume":"21","author":"Roselli","year":"2007","journal-title":"Toxicol. Vitro"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib66","series-title":"Drugs of Natural Origin: a Textbook of Pharmacognosy","author":"Samuelsson","year":"2004"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib67","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1038\/nrmicro962","article-title":"Soil-transmitted helminthiasis","volume":"2","author":"Savioli","year":"2004","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib68","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.vetpar.2010.04.017","article-title":"Efficacy of an orange oil emulsion as an anthelmintic against Haemonchus contortus in gerbils (Meriones unguiculatus) and in sheep","volume":"172","author":"Squires","year":"2010","journal-title":"Vet. Parasitol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib69","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/S0278-6915(99)00075-7","article-title":"Toxicity of selected plant volatiles in microbial and mammalian short-term assays","volume":"37","author":"Stammati","year":"1999","journal-title":"Food Chem. Toxicol."},{"issue":"Suppl. l","key":"10.1016\/j.ijpddr.2018.12.005_bib70","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.1017\/S0031182000006491","article-title":"Malnutrition and parasitic helminth infections","volume":"121","author":"Stephenson","year":"2000","journal-title":"Parasitology"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib71","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1007\/s00436-014-3969-7","article-title":"Present-day anthelmintics and perspectives on future new targets","volume":"113","author":"Taman","year":"2014","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib72","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1124\/mol.115.098285","article-title":"Menthol enhances the desensitization of human alpha3beta4 nicotinic acetylcholine receptors","volume":"88","author":"Ton","year":"2015","journal-title":"Mol. Pharmacol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib73","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1002\/ps.3280","article-title":"Quantitative structure-activity relationships of monoterpenoid binding activities to the housefly GABA receptor","volume":"68","author":"Tong","year":"2012","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib74","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1002\/ps.3443","article-title":"The phenolic monoterpenoid carvacrol inhibits the binding of nicotine to the housefly nicotinic acetylcholine receptor","volume":"69","author":"Tong","year":"2013","journal-title":"Pest Manag. Sci."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib75","doi-asserted-by":"crossref","first-page":"3059","DOI":"10.1007\/s00436-015-4508-x","article-title":"Interaction of carvacrol with the Ascaris suum nicotinic acetylcholine receptors and gamma-aminobutyric acid receptors, potential mechanism of antinematodal action","volume":"114","author":"Trailovi\u0107","year":"2015","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib76","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.cbi.2018.02.007","article-title":"Limonene: aroma of innovation in health and disease","volume":"283","author":"Vieira","year":"2018","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib77","series-title":"National Policy on Traditional Medicine and Regulation of Herbal Medicines- Report of a WHO Global Survey","author":"WHO","year":"2005"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib78","series-title":"Soil-transmitted Helminth Infections: Fact Sheet","author":"WHO","year":"2018"},{"key":"10.1016\/j.ijpddr.2018.12.005_bib79","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.bcp.2011.05.001","article-title":"Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: advantages and limitations","volume":"82","author":"Williams","year":"2011","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.ijpddr.2018.12.005_bib80","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.ijpddr.2016.02.001","article-title":"The Ascaris suum nicotinic receptor, ACR-16, as a drug target: four novel negative allosteric modulators from virtual screening","volume":"6","author":"Zheng","year":"2016","journal-title":"Int J Parasitol Drugs Drug Resist"}],"container-title":["International Journal for Parasitology: Drugs and Drug Resistance"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211320718301349?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2211320718301349?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:47:45Z","timestamp":1761922065000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2211320718301349"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":80,"alternative-id":["S2211320718301349"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpddr.2018.12.005","relation":{},"ISSN":["2211-3207"],"issn-type":[{"value":"2211-3207","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Menthol acts as a positive allosteric modulator on nematode levamisole sensitive nicotinic acetylcholine receptors","name":"articletitle","label":"Article Title"},{"value":"International Journal for Parasitology: Drugs and Drug Resistance","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpddr.2018.12.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier Ltd on behalf of Australian Society for Parasitology.","name":"copyright","label":"Copyright"}]}}