{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:14:07Z","timestamp":1788869647536,"version":"build-2803163510"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T00:00:00Z","timestamp":1692748800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Psychophysiology"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.ijpsycho.2023.08.003","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T01:10:50Z","timestamp":1692666650000},"page":"112230","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Levonorgestrel intrauterine device and depression: A Swedish register-based cohort study"],"prefix":"10.1016","volume":"193","author":[{"given":"Elin","family":"Stenhammar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per","family":"Wikman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Gemzell Danielsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Kopp-Kallner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inger","family":"Sundstr\u00f6m Poromaa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"80","key":"10.1016\/j.ijpsycho.2023.08.003_bb0005","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.psyneuen.2017.02.025","article-title":"The levonorgestrel-releasing intrauterine device potentiates stress reactivity","volume":"01","author":"Aleknaviciute","year":"2017","journal-title":"Psychoneuroendocrinology"},{"issue":"5","key":"10.1016\/j.ijpsycho.2023.08.003_bb0010","doi-asserted-by":"crossref","first-page":"325","DOI":"10.2165\/00023210-200317050-00003","article-title":"The role of hormones and hormonal treatments in premenstrual syndrome","volume":"17","author":"B\u00e4ckstr\u00f6m","year":"2003","journal-title":"CNS Drugs"},{"issue":"4","key":"10.1016\/j.ijpsycho.2023.08.003_bb0015","doi-asserted-by":"crossref","first-page":"602","DOI":"10.2105\/AJPH.90.4.602","article-title":"Psychiatric morbidity, service use, and need for care in the general population: results of The Netherlands Mental Health Survey and Incidence Study","volume":"90","author":"Bijl","year":"2000","journal-title":"Am. J. Public Health"},{"issue":"9","key":"10.1016\/j.ijpsycho.2023.08.003_bb0020","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1007\/s10654-017-0316-1","article-title":"The Swedish cause of death register","volume":"32","author":"Brooke","year":"2017","journal-title":"Eur. J. Epidemiol."},{"key":"10.1016\/j.ijpsycho.2023.08.003_bb0025","doi-asserted-by":"crossref","first-page":"100943","DOI":"10.1016\/j.yfrne.2021.100943","article-title":"Association of levonorgestrel intrauterine devices with stress reactivity, mental health, quality of life and sexual functioning: a systematic review","volume":"63","author":"B\u00fcrger","year":"2021","journal-title":"Front. Neuroendocrinol."},{"key":"10.1016\/j.ijpsycho.2023.08.003_bb0030","series-title":"Multi-generation Register 2016","author":"Centralbyr\u00e5n) SSS","year":"2017"},{"issue":"12","key":"10.1016\/j.ijpsycho.2023.08.003_bb0035","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1080\/09513590802444167","article-title":"Levonorgestrel-releasing intrauterine system: why do some women dislike it?","volume":"24","author":"Daud","year":"2008","journal-title":"Gynecol. Endocrinol."},{"issue":"1","key":"10.1016\/j.ijpsycho.2023.08.003_bb0040","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.contraception.2006.08.002","article-title":"Is there an association between the use of oral contraception and depressive symptoms in young Australian women?","volume":"75","author":"Duke","year":"2007","journal-title":"Contraception"},{"issue":"10","key":"10.1016\/j.ijpsycho.2023.08.003_bb0045","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1080\/09513590903159656","article-title":"Levonorgestrel-releasing intrauterine system \u2013 the discontinuing story","volume":"25","author":"Ewies","year":"2009","journal-title":"Gynecol. Endocrinol."},{"issue":"1","key":"10.1016\/j.ijpsycho.2023.08.003_bb0050","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jad.2006.07.003","article-title":"Indications for antidepressant drug prescribing in general practice in the Netherlands","volume":"98","author":"Gardarsdottir","year":"2007","journal-title":"J. Affect. Disord."},{"issue":"8","key":"10.1016\/j.ijpsycho.2023.08.003_bb0055","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1080\/17434440.2017.1350169","article-title":"Clarification of the role of the Jaydess(Skyla) LNG- IUS 13.5mg and Kyleena LNG-IUS 19.5mg as intrauterine contraceptive systems","volume":"14","author":"Goldstuck","year":"2017","journal-title":"Expert Rev. Med. Devices"},{"key":"10.1016\/j.ijpsycho.2023.08.003_bb0060","doi-asserted-by":"crossref","unstructured":"Grandi G, Farulla A, Sileo FG, Facchinetti F. Levonorgestrel-releasing intra-uterine systems as female contraceptives. Expert. Opin. Pharmacother. 03 May 2018;19(7):677\u201386.","DOI":"10.1080\/14656566.2018.1462337"},{"issue":"6","key":"10.1016\/j.ijpsycho.2023.08.003_bb0065","first-page":"445","article-title":"Intrauterine devices: an update","volume":"89","author":"Hardeman","year":"2014","journal-title":"Am. Fam. Physician"},{"issue":"6","key":"10.1016\/j.ijpsycho.2023.08.003_bb0070","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1080\/13625187.2020.1815008","article-title":"Comparative pharmacokinetic analysis of levonorgestrel-releasing intrauterine systems and levonorgestrel-containing contraceptives with oral or subdermal administration route","volume":"25","author":"Hofmann","year":"2020","journal-title":"Eur J Contracept Reprod Health Care"},{"issue":"03","key":"10.1016\/j.ijpsycho.2023.08.003_bb0075","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1055\/s-0036-1571438","article-title":"Intrauterine contraception","volume":"34","author":"Hsia","year":"2016","journal-title":"Semin. Reprod. Med."},{"issue":"3","key":"10.1016\/j.ijpsycho.2023.08.003_bb0080","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s00127-016-1171-1","article-title":"Social, familial and psychological risk factors for mood and anxiety disorders in childhood and early adulthood: a birth cohort study using the Danish Registry System","volume":"51","author":"Hyland","year":"2016","journal-title":"Soc. Psychiatry Psychiatr. Epidemiol."},{"issue":"1","key":"10.1016\/j.ijpsycho.2023.08.003_bb0085","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/S0015-0282(16)56455-3","article-title":"International committee for contraception research (ICCR). Health during prolonged use of levonorgestrel 20\u03bcg\/d and the Copper TCu 380Ag intrauterine contraceptive devices: a multicenter study*\u2020","volume":"61","author":"Irving","year":"1994","journal-title":"Fertil. Steril."},{"key":"10.1016\/j.ijpsycho.2023.08.003_bb0090","doi-asserted-by":"crossref","first-page":"109954","DOI":"10.1016\/j.contraception.2023.109954","article-title":"Extended use of levonorgestrel-releasing intrauterine system (LNG-IUS) 52 mg: a population pharmacokinetic approach to estimate in vivo levonorgestrel release rates and systemic exposure including comparison with two other LNG-IUSs","volume":"120","author":"Jensen","year":"2023","journal-title":"Contraception."},{"issue":"5","key":"10.1016\/j.ijpsycho.2023.08.003_bb0095","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.contraception.2005.12.005","article-title":"Effects of levonorgestrel-releasing intrauterine system on glucose and lipid metabolism: a 1-year follow-up study","volume":"73","author":"Kayikcioglu","year":"2006","journal-title":"Contraception"},{"issue":"3","key":"10.1016\/j.ijpsycho.2023.08.003_bb0100","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1080\/13625187.2018.1455179","article-title":"Health-related quality of life in young women starting hormonal contraception: a pilot study","volume":"23","author":"Kristj\u00e1nsd\u00f3ttir","year":"2018","journal-title":"Eur J Contracept Reprod Health Care"},{"issue":"9","key":"10.1016\/j.ijpsycho.2023.08.003_bb0105","doi-asserted-by":"crossref","first-page":"323","DOI":"10.2147\/IJWH.S119729","article-title":"Anxiety and depression in patients with endometriosis: impact and management challenges","volume":"16","author":"Lagan\u00e0","year":"2017","journal-title":"Int. J. Women\u2019s Health"},{"key":"10.1016\/j.ijpsycho.2023.08.003_bb0110","author":"L\u00e4kemedelsverket"},{"issue":"5","key":"10.1016\/j.ijpsycho.2023.08.003_bb0115","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.jpag.2015.11.012","article-title":"Age at time of initial sexual intercourse and health of adolescent girls","volume":"29","author":"Lara","year":"2016","journal-title":"J. Pediatr. Adolesc. Gynecol."},{"issue":"1","key":"10.1016\/j.ijpsycho.2023.08.003_bb0120","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/aogs.13055","article-title":"Contraceptive use in the Nordic countries","volume":"96","author":"Lindh","year":"2017","journal-title":"Acta Obstet. Gynecol. Scand."},{"issue":"11","key":"10.1016\/j.ijpsycho.2023.08.003_bb0125","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s10654-009-9350-y","article-title":"The Swedish personal identity number: possibilities and pitfalls in healthcare and medical research","volume":"24","author":"Ludvigsson","year":"2009","journal-title":"Eur. J. Epidemiol."},{"issue":"1","key":"10.1016\/j.ijpsycho.2023.08.003_bb0130","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2458-11-450","article-title":"External review and validation of the Swedish national inpatient register","volume":"11","author":"Ludvigsson","year":"2011","journal-title":"BMC Public Health"},{"issue":"76","key":"10.1016\/j.ijpsycho.2023.08.003_bb0135","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.psyneuen.2016.11.033","article-title":"Combined oral contraceptive use is associated with both improvement and worsening of mood in the different phases of the treatment cycle\u2014a double-blind, placebo-controlled randomized trial","volume":"01","author":"Lundin","year":"2017","journal-title":"Psychoneuroendocrinology"},{"issue":"3","key":"10.1016\/j.ijpsycho.2023.08.003_bb0140","doi-asserted-by":"crossref","first-page":"e8","DOI":"10.1136\/bmjsrh-2020-200658","article-title":"Towards individualised contraceptive counselling: clinical and reproductive factors associated with self-reported hormonal contraceptive-induced adverse mood symptoms","volume":"47","author":"Lundin","year":"2021","journal-title":"BMJ Sex Reprod. Health"},{"key":"10.1016\/j.ijpsycho.2023.08.003_bb0145","doi-asserted-by":"crossref","unstructured":"Lundin C, Wikman A, Lampa E, Bixo M, Gemzell-Danielsson K, Wikman P, et al. There is no association between combined oral hormonal contraceptives and depression: a Swedish register-based cohort study. BJOG Int. J. Obstet. Gynaecol. [Internet]. [cited 03 December 2021];n\/a(n\/a). Available at: https:\/\/doi.org\/10.1111\/1471-0528.17028.","DOI":"10.1111\/1471-0528.17028"},{"issue":"3","key":"10.1016\/j.ijpsycho.2023.08.003_bb0150","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1001\/archgenpsychiatry.2010.2","article-title":"Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies","volume":"67","author":"Luppino","year":"2010","journal-title":"Arch. Gen. Psychiatry"},{"issue":"2","key":"10.1016\/j.ijpsycho.2023.08.003_bb0155","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3109\/07853899009147248","article-title":"Levonorgestrel-releasing intrauterine device","volume":"22","author":"Luukkainen","year":"1990","journal-title":"Ann. Med."},{"key":"10.1016\/j.ijpsycho.2023.08.003_bb0160","series-title":"The Swedish Medical Birth Register; A Summary of Content and Quality (Article no. 2003\u2013112-3)","author":"National Board of Health and Welfare CfE","year":"2003"},{"key":"10.1016\/j.ijpsycho.2023.08.003_bb0165","series-title":"International Statistical Classification of Diseases and Related Health Problems: ICD-10","author":"Organization WHO","year":"1992"},{"issue":"7","key":"10.1016\/j.ijpsycho.2023.08.003_bb0170","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1007\/s11920-019-1034-z","article-title":"Hormonal contraceptives and mood: review of the literature and implications for future research","volume":"21","author":"Robakis","year":"2019","journal-title":"Curr Psychiatry Rep."},{"issue":"3","key":"10.1016\/j.ijpsycho.2023.08.003_bb0175","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1001\/jama.2022.21471","article-title":"Association between doses of levonorgestrel intrauterine systems and subsequent use of psychotropic drugs in France","volume":"329","author":"Roland","year":"2023","journal-title":"JAMA"},{"issue":"2","key":"10.1016\/j.ijpsycho.2023.08.003_bb0180","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3109\/07853899309164158","article-title":"Hormonal intrauterine devices","volume":"25","author":"Rybo","year":"1993","journal-title":"Ann. Med."},{"issue":"2","key":"10.1016\/j.ijpsycho.2023.08.003_bb0185","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.jaad.2020.02.040","article-title":"Acne vulgaris and risk of depression and anxiety: a meta-analytic review","volume":"83","author":"Samuels","year":"2020","journal-title":"J. Am. Acad. Dermatol."},{"issue":"11","key":"10.1016\/j.ijpsycho.2023.08.003_bb0190","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1001\/jamapsychiatry.2016.2387","article-title":"Association of hormonal contraception with depression","volume":"73","author":"Skovlund","year":"2016","journal-title":"JAMA Psychiatry"},{"issue":"10","key":"10.1016\/j.ijpsycho.2023.08.003_bb0195","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1007\/s40264-018-0683-x","article-title":"Cohort study of psychiatric adverse events following exposure to levonorgestrel-containing intrauterine devices in UK general practice","volume":"41","author":"Slattery","year":"2018","journal-title":"Drug Saf."},{"key":"10.1016\/j.ijpsycho.2023.08.003_bb0200","author":"Statements"},{"key":"10.1016\/j.ijpsycho.2023.08.003_bb0205","first-page":"380","article-title":"Menstrual cycle influence on cognitive function and emotion processing\u2014from a reproductive perspective","volume":"8","author":"Sundstr\u00f6m Poromaa","year":"2014","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.ijpsycho.2023.08.003_bb0210","series-title":"Mental Illness in General Health Care: An International Study","first-page":"430 s","author":"\u00dcst\u00fcn","year":"1995"},{"issue":"7","key":"10.1016\/j.ijpsycho.2023.08.003_bb0215","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1002\/pds.1294","article-title":"The new Swedish Prescribed Drug Register--opportunities for pharmacoepidemiological research and experience from the first six months","volume":"16","author":"Wettermark","year":"2007","journal-title":"Pharmacoepidemiol. Drug Saf."},{"issue":"3","key":"10.1016\/j.ijpsycho.2023.08.003_bb0220","first-page":"223","article-title":"New intrauterine technologies for contraception and treatment in nulliparous\/adolescent and parous women","volume":"1","author":"Wildemeersch","year":"2009","journal-title":"Facts Views Vis ObGyn."},{"issue":"6","key":"10.1016\/j.ijpsycho.2023.08.003_bb0225","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.contraception.2018.01.010","article-title":"The relationship between progestin hormonal contraception and depression: a systematic review","volume":"97","author":"Worly","year":"2018","journal-title":"Contraception."},{"issue":"3","key":"10.1016\/j.ijpsycho.2023.08.003_bb0230","doi-asserted-by":"crossref","first-page":"e0194773","DOI":"10.1371\/journal.pone.0194773","article-title":"Hormonal contraception increases the risk of psychotropic drug use in adolescent girls but not in adults: a pharmacoepidemiological study on 800 000 Swedish women","volume":"13","author":"Zettermark","year":"2018","journal-title":"PLoS One"}],"container-title":["International Journal of Psychophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167876023004877?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167876023004877?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,4]],"date-time":"2024-07-04T20:58:08Z","timestamp":1720126688000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167876023004877"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":46,"alternative-id":["S0167876023004877"],"URL":"https:\/\/doi.org\/10.1016\/j.ijpsycho.2023.08.003","relation":{},"ISSN":["0167-8760"],"issn-type":[{"value":"0167-8760","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Levonorgestrel intrauterine device and depression: A Swedish register-based cohort study","name":"articletitle","label":"Article Title"},{"value":"International Journal of Psychophysiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijpsycho.2023.08.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"112230"}}