{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T17:01:32Z","timestamp":1773334892032,"version":"3.50.1"},"reference-count":15,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["IJID Regions"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.ijregi.2025.100780","type":"journal-article","created":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T05:11:21Z","timestamp":1759554681000},"page":"100780","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Metagenomics next-generation sequencing for diagnosis of invasive fungal diseases in patients with hematological diseases"],"prefix":"10.1016","volume":"17","author":[{"given":"Xi","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongchao","family":"Qin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhua","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Lian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiqiang","family":"Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijregi.2025.100780_bib0001","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1093\/jac\/dkad143","article-title":"Primary prophylaxis of invasive fungal diseases in patients with haematological malignancies: 2022 update of the recommendations of the Infectious Diseases Working Party (AGIHO) of the German Society for Haematology and Medical Oncology (DGHO)","volume":"78","author":"Stemler","year":"2023","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.ijregi.2025.100780_bib0002","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/imj.15588","article-title":"Consensus guidelines for antifungal prophylaxis in haematological malignancy and haemopoietic stem cell transplantation, 2021","volume":"51","author":"Teh","year":"2021","journal-title":"Intern Med J"},{"key":"10.1016\/j.ijregi.2025.100780_bib0003","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1093\/cid\/ciz1008","article-title":"Revision and update of the consensus definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer and the mycoses study group education and research consortium","volume":"71","author":"Donnelly","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijregi.2025.100780_bib0004","doi-asserted-by":"crossref","first-page":"S121","DOI":"10.1093\/cid\/ciaa1751","article-title":"EORTC\/MSGERC definitions of invasive fungal diseases: summary of activities of the intensive care unit working group","volume":"72","author":"Bassetti","year":"2021","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijregi.2025.100780_bib0005","article-title":"Editorial: mNGS for fungal pulmonary infection diagnostics","volume":"12","author":"Li","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.ijregi.2025.100780_bib0006","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1038\/s41375-025-02586-7","article-title":"Primary antifungal prophylaxis in hematological malignancies. Updated clinical practice guidelines by the European Conference on Infections in Leukemia (ECIL)","volume":"39","author":"Pagano","year":"2025","journal-title":"Leukemia"},{"key":"10.1016\/j.ijregi.2025.100780_bib0007","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.cmi.2024.08.006","article-title":"Invasive fungal disease in the immunocompromised host: changing epidemiology, new antifungal therapies, and management challenges","volume":"31","author":"Giannella","year":"2025","journal-title":"Clin Microbiol Infect"},{"key":"10.1016\/j.ijregi.2025.100780_bib0008","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1007\/s00063-023-01051-6","article-title":"Antiinfektive Therapie von Pilzinfektionen durch Candida und Aspergillus [Anti-infective treatment of fungal infections by Candida and Aspergillus","volume":"118","author":"Salzer","year":"2023","journal-title":"Med Klin Intensivmed Notfmed"},{"key":"10.1016\/j.ijregi.2025.100780_bib0009","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1186\/s12879-019-3901-y","article-title":"A population-based analysis of invasive fungal disease in haematology-oncology patients using data linkage of state-wide registries and administrative databases: 2005\u20132016","volume":"19","author":"Valentine","year":"2019","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.ijregi.2025.100780_bib0010","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1093\/cid\/ciac623","article-title":"Empiric vs preemptive antifungal strategy in high-risk neutropenic patients on fluconazole prophylaxis: a randomized trial of the European Organization for Research and Treatment of Cancer","volume":"76","author":"Maertens","year":"2023","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.ijregi.2025.100780_bib0011","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s12288-024-01790-2","article-title":"Antifungal prophylaxis and treatment of breakthrough invasive fungal diseases in high-risk hematology patients: a prospective observational multicenter study","volume":"41","author":"Metan","year":"2025","journal-title":"Indian J Hematol Blood Transfus"},{"key":"10.1016\/j.ijregi.2025.100780_bib0012","doi-asserted-by":"crossref","DOI":"10.1136\/rmdopen-2023-003281","article-title":"Invasive fungal diseases in patients with autoimmune diseases: a case series from the French RESSIF network","volume":"9","author":"Galmiche","year":"2023","journal-title":"RMD Open"},{"key":"10.1016\/j.ijregi.2025.100780_bib0013","doi-asserted-by":"crossref","first-page":"212","DOI":"10.24293\/ijcpml.v27i2.1639","article-title":"C-reactive protein as a fungal infection marker in acute leukemia patients","volume":"27","author":"Sidharta","year":"2021","journal-title":"Indonesian J Clin Pathol Med Laboratory"},{"key":"10.1016\/j.ijregi.2025.100780_bib0014","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2024.1382720","article-title":"A prediction model for secondary invasive fungal infection among severe SARS-CoV-2 positive patients in ICU","volume":"14","author":"Su","year":"2024","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.ijregi.2025.100780_bib0015","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1365-2141.2005.05498.x","article-title":"Cytokines and fungal infections","volume":"129","author":"Antachopoulos","year":"2005","journal-title":"Br J Haematol"}],"container-title":["IJID Regions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772707625002140?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772707625002140?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T05:20:41Z","timestamp":1773292841000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772707625002140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":15,"alternative-id":["S2772707625002140"],"URL":"https:\/\/doi.org\/10.1016\/j.ijregi.2025.100780","relation":{},"ISSN":["2772-7076"],"issn-type":[{"value":"2772-7076","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Metagenomics next-generation sequencing for diagnosis of invasive fungal diseases in patients with hematological diseases","name":"articletitle","label":"Article Title"},{"value":"IJID Regions","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijregi.2025.100780","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.","name":"copyright","label":"Copyright"}],"article-number":"100780"}}