{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:41:49Z","timestamp":1788871309505,"version":"build-2803163510"},"reference-count":27,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,10,1]],"date-time":"2005-10-01T00:00:00Z","timestamp":1128124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","redjournal.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2005,10]]},"DOI":"10.1016\/j.ijrobp.2005.02.015","type":"journal-article","created":{"date-parts":[[2005,4,27]],"date-time":"2005-04-27T07:41:32Z","timestamp":1114587692000},"page":"472-478","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":38,"title":["Acute genitourinary toxicity after high dose rate (HDR) brachytherapy combined with hypofractionated external-beam radiation therapy for localized prostate cancer: Second analysis to determine the correlation between the urethral dose in HDR brachytherapy and the severity of acute genitourinary toxicity"],"prefix":"10.1016","volume":"63","author":[{"given":"Tetsuo","family":"Akimoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Katoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin-ei","family":"Noda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuto","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takumi","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bunzo","family":"Kashiwagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Nakano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2005.02.015_bib1","series-title":"Radiotherapeutic management of prostate adenocarcinoma","first-page":"21","article-title":"Three-dimensional conformal radiation therapy for prostate cancer","year":"1999"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib2","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1053\/srao.2002.00000","article-title":"Intensity-modulated radiation therapy for prostate cancer","volume":"12","author":"Zelefsky","year":"2002","journal-title":"Semin Radiat Oncol"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib3","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0167-8140(99)00100-0","article-title":"Clinical experience with intensity modulated radiation therapy (IMRT) in prostate cancer","volume":"55","author":"Zelefsky","year":"2000","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib4","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1016\/S0360-3016(02)02829-8","article-title":"Prostate cancer radiation dose response","volume":"53","author":"Pollack","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib5","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0360-3016(98)00089-3","article-title":"Dose escalation with 3D conformal treatment","volume":"41","author":"Hanks","year":"1998","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib6","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/S0360-3016(96)00602-5","article-title":"Optimization of conformal radiation treatment of prostate cancer","volume":"37","author":"Hanks","year":"1997","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib7","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/S0360-3016(99)00069-3","article-title":"American Brachytherapy Society (ABS) recommendations for transperineal permanent brachytherapy of prostate cancer","volume":"44","author":"Nag","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib8","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0360-3016(01)01601-7","article-title":"10-year biochemical (prostate-specific antigen) control of prostate cancer with (125)I brachytherapy","volume":"51","author":"Grimm","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib9","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/S0360-3016(03)00739-9","article-title":"Ten-year biochemical relapse-free survival after external beam radiation and brachytherapy for localized prostate cancer","volume":"57","author":"Sylvester","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib10","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.radonc.2004.01.020","article-title":"Results of permanent prostate brachytherapy, 13 years of experience at a single institution","volume":"71","author":"Battermann","year":"2004","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib11","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0360-3016(00)00436-3","article-title":"Interim report of image-guided conformal high-dose-rate brachytherapy for patients with unfavorable prostate cancer","volume":"47","author":"Martinez","year":"2000","journal-title":"Int J Radiat Oncol Biol Phy"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib12","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S0167-8140(02)00408-5","article-title":"Results of high dose rate afterloading brachytherapy boost to conventional external beam radiation therapy for initial and locally advanced prostate cancer","volume":"66","author":"Pellizzon","year":"2003","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib13","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.ijrobp.2003.11.035","article-title":"Clinical results of combined treatment conformal high-dose-rate iridium-192 brachytherapy and external beam radiotherapy using staging lymphadenectomy for localized prostate cancer","volume":"59","author":"Hiratsuka","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib14","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/j.ijrobp.2003.08.003","article-title":"Long-term outcome by risk factors using conformal high-dose-rate brachytherapy (HDR-BT) boost with or without neoadjuvant androgen suppression for localized prostate cancer","volume":"58","author":"Galalae","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib15","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.ijrobp.2003.10.033","article-title":"External beam radiation therapy for clinically node negative localized hormone refractory prostate cancer","volume":"59","author":"Akimoto","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib16","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.ijrobp.2004.07.695","article-title":"Rectal bleeding after hypofractionated radiotherapy for prostate cancer","volume":"60","author":"Akimoto","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib17","unstructured":"Akimoto T, Ito K, Saitoh J, et al. Acute genitourinary toxicity after high dose rate (HDR) brachytherapy combined with hypofractionated external-beam radiation therapy for localized prostate cancer: Correlation between the urethral dose in HDR brachytherapy and the severity of acute genitourinary toxicity. Int J Radiat Oncol Biol Phys. In press."},{"key":"10.1016\/j.ijrobp.2005.02.015_bib18","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0360-3016(99)00330-2","article-title":"A simple method of obtaining equivalent doses for use in HDR brachytherapy","volume":"46","author":"Nag","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib19","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1016\/0360-3016(95)00060-C","article-title":"Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC)","volume":"31","author":"Cox","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib20","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Non-parametric estimation from incomplete observation","volume":"53","author":"Kaplan","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib21","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/S0360-3016(03)00131-7","article-title":"Analysis of interaction between number of implant catheters and dose-volume histograms in prostate high-dose-rate brachytherapy using a computer model","volume":"56","author":"Charra-Brunaud","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib22","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0167-8140(03)00004-5","article-title":"Predictive factors of acute urinary morbidity after iodine-125 brachytherapy for localized prostate cancer","volume":"66","author":"Salem","year":"2003","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib23","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0360-3016(01)02658-X","article-title":"Factors influencing risk of acute urinary retention after TRUS-guided permanent prostate seed implantation","volume":"52","author":"Crook","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib24","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1046\/j.1440-1673.2002.01091.x","article-title":"Dose distribution and morbidity after high dose rate brachytherapy for prostate cancer","volume":"46","author":"Duchesne","year":"2002","journal-title":"Australas Radiol"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib25","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.radonc.2004.08.014","article-title":"Anatomy based inverse planning in HDR prostate brachytherapy","volume":"73","author":"Kolkman-Deurloo","year":"2004","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib26","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.brachy.2004.05.007","article-title":"Comparison of inverse planning simulated annealing and geometrical optimization for prostate high-dose-rate brachytherapy","volume":"3","author":"Hsu","year":"2004","journal-title":"Brachytherapy"},{"key":"10.1016\/j.ijrobp.2005.02.015_bib27","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S0360-3016(02)02897-3","article-title":"Early clinical experience with anatomy-based inverse planning dose optimization for high-dose-rate boost of the prostate","volume":"54","author":"Lachance","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301605003512?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301605003512?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T09:39:57Z","timestamp":1759743597000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301605003512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,10]]}},"alternative-id":["S0360301605003512"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2005.02.015","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2005,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acute genitourinary toxicity after high dose rate (HDR) brachytherapy combined with hypofractionated external-beam radiation therapy for localized prostate cancer: Second analysis to determine the correlation between the urethral dose in HDR brachytherapy and the severity of acute genitourinary toxicity","name":"articletitle","label":"Article Title"},{"value":"International Journal of Radiation Oncology*Biology*Physics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ijrobp.2005.02.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}