{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T15:48:39Z","timestamp":1784735319078,"version":"3.55.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,8,1]],"date-time":"2007-08-01T00:00:00Z","timestamp":1185926400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2007,8]]},"DOI":"10.1016\/j.ijrobp.2007.01.062","type":"journal-article","created":{"date-parts":[[2007,5,8]],"date-time":"2007-05-08T13:33:55Z","timestamp":1178631235000},"page":"1310-1319","source":"Crossref","is-referenced-by-count":34,"title":["3D MR Sialography as a Tool to Investigate Radiation-Induced Xerostomia: Feasibility Study"],"prefix":"10.1016","volume":"68","author":[{"given":"Eleftheria","family":"Astreinidou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith M.","family":"Roesink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cornelis P.J.","family":"Raaijmakers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lambertus W.","family":"Bartels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theo D.","family":"Witkamp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan J.W.","family":"Lagendijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris H.J.","family":"Terhaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2007.01.062_bib1","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1002\/hed.20045","article-title":"Radiation-induced xerostomia in patients with head and neck cancer: Pathogenesis, impact on quality of life, and management","volume":"26","author":"Chambers","year":"2004","journal-title":"Head Neck"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib2","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.ijrobp.2006.06.045","article-title":"Intensity-modulated radiotherapy significantly reduces xerostomia compared with conventional radiotherapy","volume":"66","author":"Braam","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib3","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/S0360-3016(96)00604-9","article-title":"Mastication and swallowing in patients with postirradiation xerostomia","volume":"37","author":"Hamlet","year":"1997","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib4","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.ijrobp.2004.12.015","article-title":"Long-term parotid gland function after radiotherapy","volume":"62","author":"Braam","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib5","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1002\/hed.20162","article-title":"Quality of life, mucositis, and xerostomia from radiotherapy for head and neck cancers: A report from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent mucositis","volume":"27","author":"Duncan","year":"2005","journal-title":"Head Neck"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib6","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0360-3016(03)00361-4","article-title":"Quality of life after parotid-sparing IMRT for head-and-neck cancer: A prospective longitudinal study","volume":"57","author":"Lin","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib7","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/j.ijrobp.2004.12.051","article-title":"On the mechanism of salivary gland radiosensitivity","volume":"62","author":"Konings","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib8","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1002\/1097-0142(197607)38:1<273::AID-CNCR2820380141>3.0.CO;2-8","article-title":"Radiation-induced xerostomia in cancer patients","volume":"38","author":"Dreizen","year":"1976","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib9","series-title":"Radioisotope study of salivary glands","first-page":"52","article-title":"Radioisotopic studies under pathologic conditions","author":"De Rossi","year":"1987"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib10","doi-asserted-by":"crossref","first-page":"873","DOI":"10.2214\/ajr.170.4.9530026","article-title":"MR hydrography: Theory and practice of static fluid imaging","volume":"170","author":"Jara","year":"1998","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib11","first-page":"1485","article-title":"Comparative study of MR sialography and digital subtraction sialography for benign salivary gland disorders","volume":"23","author":"Kalinowski","year":"2002","journal-title":"Am J Neuroradiol"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib12","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1148\/radiology.217.2.r00oc02347","article-title":"Sialolithiasis and salivary ductal stenosis: Diagnostic accuracy of MR sialography with a three-dimensional extended-phase conjugate-symmetry rapid spin-echo sequence","volume":"216","author":"Becker","year":"2000","journal-title":"Radiology"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib13","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/rheumatology\/keh187","article-title":"Ultrasonography of salivary glands in primary Sj\u00f6gren\u2019s syndrome","volume":"43","author":"Niemela","year":"2004","journal-title":"Rheumatology (Oxf)"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib14","first-page":"120","article-title":"MR microscopy of the parotid glands in patients with Sj\u00f6gren\u2019s syndrome: Quantitative MR diagnostic criteria","volume":"26","author":"Takagi","year":"2005","journal-title":"Am J Neuroradiol"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib15","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/s002340050704","article-title":"3D T2-weighted fast spin-echo MRI sialography of the parotid gland","volume":"41","author":"Sartoretti-Schefer","year":"1999","journal-title":"Neuroradiology"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib16","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1002\/jmri.20659","article-title":"3D MR sialography protocol for post-radiotherapy follow-up of the salivary duct system","volume":"24","author":"Astreinidou","year":"2006","journal-title":"J Magn Reson Imag"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib17","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/S0360-3016(03)01391-9","article-title":"Level II lymph nodes and radiation-induced xerostomia","volume":"58","author":"Astreinidou","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib18","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0167-8140(01)00449-2","article-title":"Intensity-modulated radiation therapy reduces late salivary toxicity without compromising tumor control in patients with oropharyngeal carcinoma: A comparison with conventional techniques","volume":"61","author":"Chao","year":"2001","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib19","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0360-3016(02)04617-5","article-title":"Simultaneous integrated boost intensity-modulated radiotherapy for locally advanced head-and-neck squamous cell carcinomas","volume":"56","author":"Wu","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib20","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0360-3016(01)01512-7","article-title":"Xerostomia and its predictors following parotid-sparing irradiation of head-and-neck cancer","volume":"50","author":"Eisbruch","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib21","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1016\/j.ijrobp.2005.08.018","article-title":"Radioprotective effect of amifostine on parotid gland functioning is region dependent","volume":"63","author":"Konings","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib22","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.ijrobp.2005.06.042","article-title":"Secondary radiation damage as the main cause for unexpected volume effects: A histopathologic study of the parotid gland","volume":"64","author":"Konings","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib23","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1016\/j.ijrobp.2004.12.035","article-title":"Volume effects and region-dependent radiosensitivity of the parotid gland","volume":"62","author":"Konings","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib24","doi-asserted-by":"crossref","first-page":"N101","DOI":"10.1088\/0031-9155\/50\/10\/N01","article-title":"Assessment of rigid multi-modality image registration consistency using the multiple sub-volume registration (MSR) method","volume":"50","author":"Ceylan","year":"2005","journal-title":"Phys Med Biol"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib25","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1016\/S0360-3016(01)01717-5","article-title":"Quantitative dose-volume response analysis of changes in parotid gland function after radiotherapy in the head-and-neck region","volume":"51","author":"Roesink","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib26","first-page":"271","article-title":"Postirradiation sialadenitis: A study of the clinical features, histopathologic changes and serum enzyme variations following irradiation of human salivary glands","volume":"114","author":"Kashima","year":"1965","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib27","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.1007\/s003300000728","article-title":"MRI appearance of radiation-induced changes of normal cervical tissues","volume":"11","author":"Nomayr","year":"2001","journal-title":"Eur Radiol"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib28","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.ijrobp.2006.05.002","article-title":"Grading xerostomia by physicians or by patients after intensity-modulated radiotherapy of head-and-neck cancer","volume":"66","author":"Meirovitz","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib29","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.ijrobp.2004.12.076","article-title":"Dose-volume modeling of salivary function in patients with head-and-neck cancer receiving radiotherapy","volume":"62","author":"Blanco","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"Suppl","key":"10.1016\/j.ijrobp.2007.01.062_bib30","doi-asserted-by":"crossref","first-page":"S145","DOI":"10.1016\/S0167-8140(05)81292-7","article-title":"The potential of using MRI to obtain spatial information about the salivary gland function","volume":"76","author":"Astreinidou","year":"2005","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib31","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.tripleo.2004.11.053","article-title":"The functional evaluation of salivary glands using dynamic MR sialography following citric acid stimulation: A preliminary study","volume":"100","author":"Morimoto","year":"2005","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib32","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/jmri.1177","article-title":"Functional evaluation with intravoxel incoherent motion echo-planar MRI in irradiated salivary glands: A correlative study with salivary gland scintigraphy","volume":"14","author":"Zhang","year":"2001","journal-title":"J Magn Reson Imag"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib33","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1148\/radiol.2352040127","article-title":"Gustatory stimulation changes the apparent diffusion coefficient of salivary glands: Initial experience","volume":"235","author":"Thoeny","year":"2005","journal-title":"Radiology"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib34","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1055\/s-2004-813564","article-title":"Functional imaging of parotid glands: Diffusion-weighted echo-planar MRI before and after stimulation","volume":"176","author":"Habermann","year":"2004","journal-title":"Fortschr Rontgenstr"},{"key":"10.1016\/j.ijrobp.2007.01.062_bib35","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1002\/jmri.20196","article-title":"Diffusion-weighted imaging of the parotid gland: Influence of the choice of the b-values on the apparent diffusion coefficient value","volume":"20","author":"Thoeny","year":"2004","journal-title":"J Magn Reson Imag"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301607003173?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301607003173?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,7]],"date-time":"2019-01-07T19:58:02Z","timestamp":1546891082000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301607003173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,8]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,8]]}},"alternative-id":["S0360301607003173"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2007.01.062","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2007,8]]}}}