{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T19:54:41Z","timestamp":1784231681398,"version":"3.55.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2007,11,1]],"date-time":"2007-11-01T00:00:00Z","timestamp":1193875200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2007,11]]},"DOI":"10.1016\/j.ijrobp.2007.04.029","type":"journal-article","created":{"date-parts":[[2007,7,3]],"date-time":"2007-07-03T11:21:07Z","timestamp":1183461667000},"page":"1181-1186","source":"Crossref","is-referenced-by-count":41,"title":["A Multicenter Phase II Study of Local Radiation Therapy for Stage IEA Mucosa-Associated Lymphoid Tissue Lymphomas: A Preliminary Report From the Japan Radiation Oncology Group (JAROG)"],"prefix":"10.1016","volume":"69","author":[{"given":"Koichi","family":"Isobe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshikazu","family":"Kagami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Higuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Kodaira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masatoshi","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoto","family":"Shikama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Nakazawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ichiro","family":"Fukuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiji","family":"Nihei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kana","family":"Ito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teruki","family":"Teshima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiro","family":"Matsuno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiko","family":"Oguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2007.04.029_bib1","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1002\/1097-0142(19831015)52:8<1410::AID-CNCR2820520813>3.0.CO;2-3","article-title":"Malignant lymphoma of mucosa-associated lymphoid tissue: A distinctive type of B-cell lymphoma","volume":"52","author":"Isaacson","year":"1983","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib2","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1182\/blood.V84.5.1361.1361","article-title":"A revised European-American classification of lymphoid neoplasms: A proposal from the\u00a0International Lymphoma Study Group","volume":"84","author":"Harris","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib3","series-title":"World Health Organization classifications of tumors: Pathology and genetics of tumours of haematopoietic and lymphoid tissue","first-page":"157","article-title":"Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)","author":"Isaacson","year":"2001"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib4","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1046\/j.1440-1827.2000.01108.x","article-title":"Lymphoma Study Group of Japanese Pathologists: The World Health Organization classification of malignant lymphomas in Japan: Incidence of recently recognized entities","volume":"50","year":"2000","journal-title":"Pathol Int"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib5","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1023\/A:1008396618983","article-title":"Gastric MALT lymphoma; from concept to cure","volume":"10","author":"Isaacson","year":"1999","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib6","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1200\/JCO.1997.15.4.1624","article-title":"Mucosa-associated lymphoid tissue gastrointestinal and nongastrointestinal lymphoma behavior; analysis of 108 patients","volume":"15","author":"Thieblemont","year":"1997","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib7","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1200\/JCO.1999.17.4.1254","article-title":"Nongastrointestinal low-grade mucosa-associated lymphoid tissue lymphoma; analysis of 75 patients","volume":"17","author":"Zinzani","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib8","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1182\/blood.V95.3.802.003k19_802_806","article-title":"Mucosa-associated lymphoid tissue lymphoma is a disseminated disease in one third of 158 patients analyzed","volume":"95","author":"Thieblemont","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib9","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0360-3016(00)00628-3","article-title":"Mucosa-associated lymphoid tissue lymphoma with initial supradiaphragmatic presentation; natural history and patterns of disease progression","volume":"48","author":"Liao","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib10","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1136\/bjo.84.8.907","article-title":"Histological features of ocular adnexal lymphoma (REAL classification) and their association with patient morbidity and survival","volume":"84","author":"Jenkins","year":"2000","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib11","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1182\/blood-2002-04-1279","article-title":"Nongastric marginal zone B-cell lymphoma of mucosa- associated lymphoid tissue","volume":"101","author":"Zucca","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib12","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/0360-3016(94)00416-1","article-title":"Radiation therapy for primary orbital lymphoma","volume":"31","author":"Chao","year":"1995","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib13","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0360-3016(98)00535-5","article-title":"Radiotherapy in the management of orbital lymphoma","volume":"44","author":"Bolek","year":"1999","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib14","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0167-8140(01)00338-3","article-title":"Clinical stage IEA\u2013IIEA orbital lymphomas: Outcomes in the era of modern staging and treatment","volume":"59","author":"Pelloski","year":"2001","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib15","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0167-8140(00)00328-5","article-title":"Orbital lymphoma: Radiotherapy outcome and complications","volume":"59","author":"Stafford","year":"2001","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib16","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/S0360-3016(01)02729-8","article-title":"Primary radiotherapy for localized orbital MALT lymphoma","volume":"52","author":"Le","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib17","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1016\/S0360-3016(03)00767-3","article-title":"Ocular adnexal lymphoma: Clinical behavior of distinct world health organization classification subtypes","volume":"57","author":"Fung","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib18","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/S0360-3016(03)00506-6","article-title":"Treatment results of radiotherapy for malignant lymphoma of the orbit and histopathologic review according to the WHO classification","volume":"57","author":"Hasegawa","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib19","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/S0360-3016(02)04159-7","article-title":"Outcome and prognostic factor in orbital lymphoma: A rare cancer network study on 90 consecutive patients treated with radiotherapy","volume":"55","author":"Martinet","year":"2003","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib20","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1016\/j.ijrobp.2004.05.066","article-title":"Efficacy and treatment-related toxicity of radiotherapy for early-stage primary non-Hodgkin lymphoma of the parotid gland","volume":"60","author":"Olivier","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib21","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1016\/j.ijrobp.2005.03.005","article-title":"Radiation therapy for orbital lymphoma","volume":"63","author":"Zhou","year":"2005","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib22","doi-asserted-by":"crossref","first-page":"2236","DOI":"10.1002\/cncr.11317","article-title":"Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue of the head and neck area","volume":"67","author":"Wenzel","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib23","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1016\/S0360-3016(01)01549-8","article-title":"Stage I and II MALT lymphoma: Results of treatment with radiotherapy","volume":"50","author":"Tsang","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib24","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1016\/S0360-3016(01)02714-6","article-title":"Treatment outcome of mucosa-associated lymphoid tissue\/ marginal zone non-Hodgkin's lymphoma","volume":"52","author":"Hitchcock","year":"2002","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib25","doi-asserted-by":"crossref","first-page":"4157","DOI":"10.1200\/JCO.2003.06.085","article-title":"Localized mucosa-associated lymphoid tissue lymphoma treated with radiation therapy has excellent outcome","volume":"21","author":"Tsang","year":"2003","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib26","doi-asserted-by":"crossref","first-page":"1916","DOI":"10.1200\/JCO.1998.16.5.1916","article-title":"Treatment of mucosa-associated lymphoid tissue lymphoma of the stomach with radiation alone","volume":"16","author":"Schechter","year":"1998","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib27","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1002\/(SICI)1097-0142(19990101)85:1<9::AID-CNCR2>3.0.CO;2-S","article-title":"Mucosa-associated lymphoid tissue lymphoma of the stomach","volume":"85","author":"Fung","year":"1999","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib28","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observations","volume":"53","author":"Kaplan","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib29","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1200\/JCO.1999.17.4.1244","article-title":"Report of an international workshop to standardize response criteria for non-Hodgkin's lymphomas","volume":"17","author":"Cheson","year":"1999","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib30","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1002\/cncr.11539","article-title":"Radiotherapy for extranodal, marginal zone, B-cell lymphoma of mucosa-associated lymphoid tissue originating in the ocular adnexa","volume":"98","author":"Uno","year":"2003","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib31","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.ijrobp.2004.03.039","article-title":"Orbital lymphoma: Is it necessary to treat the entire orbit?","volume":"60","author":"Pfeffer","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib32","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S0360-3016(99)00522-2","article-title":"Low-grade MALT lymphoma of the stomach: A review of treatment options","volume":"46","author":"Schechter","year":"2000","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib33","doi-asserted-by":"crossref","first-page":"6415","DOI":"10.1200\/JCO.2005.05.018","article-title":"State-of-the-art therapeutics: Marginal zone lymphoma","volume":"23","author":"Bertoni","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib34","first-page":"494","article-title":"A critical review of the effect of Helicobacter pylori eradication on gastric MALT lymphoma","volume":"2","author":"Ferreri","year":"2002","journal-title":"Curr Gastroenterol Rep"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib35","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1200\/JCO.2001.19.7.2041","article-title":"Complete remission of primary gastric high-grade B-cell gastric lymphoma after cure of Helicobacter pylori infection","volume":"19","author":"Morgner","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib36","doi-asserted-by":"crossref","first-page":"4245","DOI":"10.1200\/JCO.2001.19.22.4245","article-title":"Prospective study of Helicobacter pylori eradication therapy in stage IE high-grade mucosa-associated lymphoid tissue lymphoma of the stomach","volume":"19","author":"Chen","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib37","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1093\/jnci\/djh102","article-title":"Evidence for an association between Chlamydia psittaci and ocular adnexal lymphomas","volume":"96","author":"Ferreri","year":"2004","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib38","doi-asserted-by":"crossref","first-page":"5067","DOI":"10.1200\/JCO.2005.07.083","article-title":"Regression of ocular adnexal lymphoma after Chlamydia psittaci\u2013eradicating antibiotic therapy","volume":"23","author":"Lettini","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib39","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/S0190-9622(97)80405-7","article-title":"Borrelia burgdorferi associated primary cutaneous B cell lymphoma: Complete clearing of skin lesions after antibiotic pulse therapy or intralesional injection of interferon alfa-2a","volume":"36","author":"Kutting","year":"1997","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib40","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S0046-8177(00)80233-6","article-title":"Eradiation of Borrelia burgdorferi infection in primary marginal zone B\u2013cell lymphoma of the skin","volume":"31","author":"Roggero","year":"2000","journal-title":"Hum Pathol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib41","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1200\/JCO.2001.19.6.1600","article-title":"Long-term persistence of monoclonal B cells after cure of Helicobacter pylori infection and complete histologic remission in gastric mucosa-associated lymphoid tissue B-cell lymphoma","volume":"19","author":"Thiede","year":"2001","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib42","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1182\/blood-2005-06-2332","article-title":"Ocular adnexal lymphoma: A clinicopathologic study of a large cohort of patients with no evidence for an association with","volume":"107","author":"Rosado","year":"2006","journal-title":"Chlamydia psittaci. Blood"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib43","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/jnci\/djj079","article-title":"Evidence for an association between Chlamydia psittaci and ocular adnexal lymphoma","volume":"98","author":"Cremoux","year":"2006","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib44","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1093\/annonc\/mdj143","article-title":"\u2018Blind\u2019 antibiotic treatment targeting Chlamydia is not effective in patients with MALT lymphoma of the ocular adnexa","volume":"17","author":"Grunberger","year":"2006","journal-title":"Ann Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib45","doi-asserted-by":"crossref","first-page":"3872","DOI":"10.1200\/JCO.2002.05.117","article-title":"Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type with cladribine: A phase II study","volume":"20","author":"Joger","year":"2002","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib46","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1002\/cncr.20237","article-title":"Fludarabine-containing chemotherapy as frontline treatment on nongastrointestinal mucosa-associated lymphoid tissue lymphoma","volume":"100","author":"Zinzani","year":"2004","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib47","doi-asserted-by":"crossref","first-page":"2741","DOI":"10.1182\/blood-2002-11-3496","article-title":"Clinical activity of rituximab in extranodal marginal zone B-cell lymphoma of MALT type","volume":"102","author":"Conconi","year":"2003","journal-title":"Blood"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib48","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1200\/JCO.2005.08.128","article-title":"Clinical activity of rituximab in gastric marginal zone non-Hodgkin's lymphoma resistant to or not eligible for anti\u2013Helicobacter pylori therapy","volume":"23","author":"Martinelli","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2007.04.029_bib49","doi-asserted-by":"crossref","first-page":"3349","DOI":"10.1158\/1078-0432.CCR-04-2282","article-title":"High relapse rate in patients with MALT lymphoma warrants lifelong follow-up","volume":"11","author":"Raderer","year":"2005","journal-title":"Clin Cancer Res"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301607007006?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301607007006?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,24]],"date-time":"2020-04-24T00:20:18Z","timestamp":1587687618000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301607007006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["S0360301607007006"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2007.04.029","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2007,11]]}}}