{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T21:14:40Z","timestamp":1789593280381,"version":"build-2803163510"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Oncology*Biology*Physics"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1016\/j.ijrobp.2008.05.041","type":"journal-article","created":{"date-parts":[[2008,8,16]],"date-time":"2008-08-16T13:48:29Z","timestamp":1218894509000},"page":"1017-1022","source":"Crossref","is-referenced-by-count":16,"title":["Obesity and Risk of Biochemical Failure for Patients Receiving Salvage Radiotherapy After Prostatectomy"],"prefix":"10.1016","volume":"73","author":[{"given":"Christopher R.","family":"King","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael T.","family":"Spiotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel S.","family":"Kapp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ijrobp.2008.05.041_bib1","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1056\/NEJMoa021423","article-title":"Overweight, obesity, and mortality from cancer in a prospectively studied cohort of US adults","volume":"348","author":"Calle","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib2","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/S0140-6736(08)60269-X","article-title":"Body-mass index and incidence of cancer: A systematic review and meta-analysis of prospective observational studies","volume":"371","author":"Renshaw","year":"2008","journal-title":"Lancet"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib3","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1097\/01.ju.0000135302.58378.ae","article-title":"Obesity and biochemical outcome following radical prostatectomy for organ confined disease with negative surgical margins","volume":"172","author":"Freedland","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib4","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/j.urology.2005.05.040","article-title":"Impact of obesity on prostate cancer recurrence after radical prostatectomy: Data from CaPSURE","volume":"66","author":"Bassett","year":"2005","journal-title":"Urology"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib5","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1200\/JCO.2004.03.132","article-title":"Pathologic variables and recurrence rates as related to obesity and race in men with prostate cancer undergoing radical prostatectomy","volume":"22","author":"Amling","year":"2004","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib6","doi-asserted-by":"crossref","first-page":"6889","DOI":"10.1158\/1078-0432.CCR-04-1977","article-title":"Obesity, weight gain, and risk of biochemical failure among prostate cancer patients following prostatectomy","volume":"11","author":"Strom","year":"2005","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib7","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.juro.2006.08.097","article-title":"Does body mass index affect preoperative prostate specific antigen velocity or pathological outcomes after radical prostatectomy?","volume":"177","author":"Loeb","year":"2007","journal-title":"J Urol"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib8","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.1002\/cncr.20991","article-title":"Body mass index is weakly associated with, and not a helpful predictor of, disease progression in men with clinically localized prostate carcinoma treated with radical prostatectomy","volume":"103","author":"Mallah","year":"2005","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib9","doi-asserted-by":"crossref","first-page":"2883","DOI":"10.1158\/1078-0432.CCR-04-2257","article-title":"Stronger association between obesity and biochemical progression after radical prostatectomy among men treated in the last 10 years","volume":"11","author":"Freedland","year":"2005","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib10","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0022-5347(05)64687-3","article-title":"Body size and serum levels of insulin and leptin in relation to the risk of benign prostatic hyperplasia","volume":"168","author":"Dahle","year":"2002","journal-title":"J Urol"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib11","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1016\/j.ejca.2005.09.003","article-title":"Hyperinsulinemia: A prospective risk factor for lethal clinical prostate cancer","volume":"41","author":"Hammarsten","year":"2005","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib12","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1056\/NEJMoa032975","article-title":"Preoperative PSA velocity and the risk of death from prostate cancer after radical prostatectomy","volume":"351","author":"D'Amico","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib13","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1464-410X.2007.06897.x","article-title":"Obesity as a predictor of biochemical recurrence and survival after radiation therapy for prostate cancer","volume":"100","author":"Palma","year":"2007","journal-title":"BJU Int"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib14","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1002\/cncr.22025","article-title":"Influence of obesity on biochemical and clinical failure after external-beam radiotherapy for localized prostate cancer","volume":"107","author":"Strom","year":"2006","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib15","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1002\/cncr.22873","volume":"110","author":"Stroup","year":"2007","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib16","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1002\/cncr.22564","article-title":"Influence of body mass index on prostate-specific antigen failure after androgen suppression and radiation therapy for localized prostate cancer","volume":"109","author":"Efstathiou","year":"2007","journal-title":"Cancer"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib17","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.urology.2004.08.044","article-title":"Influence of body mass index on biochemical outcome after permanent prostate brachytherapy","volume":"65","author":"Merrick","year":"2005","journal-title":"Urology"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib18","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1097\/COC.0b013e318068b506","article-title":"Obesity is not predictive of overall survival following permanent prostate brachytherapy","volume":"30","author":"Merrick","year":"2007","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijrobp.2007.11.073","article-title":"Body mass index and prostate-specific antigen failure following brachytherapy for localized prostate cancer","author":"Efstathiou","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"issue":"Suppl. 2","key":"10.1016\/j.ijrobp.2008.05.041_bib20","first-page":"51S","article-title":"Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults\u2014The evidence report","volume":"6","author":"National Institutes of Health","year":"1998","journal-title":"Obes Res"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib21","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observations","volume":"53","author":"Kaplan","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib22","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life tables","volume":"34","author":"Cox","year":"1972","journal-title":"J R Stat Soc Series B"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib23","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1093\/aje\/kwk052","article-title":"Relaxing the rule of ten events per variable in logistic and Cox regression","volume":"165","author":"Vittinghoff","year":"2007","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib24","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ijrobp.2007.09.047","article-title":"Improved outcomes with higher doses for patients receiving radiotherapy after prostatectomy","volume":"71","author":"King","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib25","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.ijrobp.2007.10.008","article-title":"Radiotherapy after prostatectomy: Is the evidence for dose escalation out there?","volume":"71","author":"King","year":"2008","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"10.1016\/j.ijrobp.2008.05.041_bib26","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ijrobp.2003.12.027","article-title":"Daily electronic portal imaging for morbidly obese men undergoing radiotherapy for localized prostate cancer","volume":"59","author":"Millender","year":"2004","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["International Journal of Radiation Oncology*Biology*Physics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301608009553?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0360301608009553?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,31]],"date-time":"2025-01-31T15:05:35Z","timestamp":1738335935000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0360301608009553"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["S0360301608009553"],"URL":"https:\/\/doi.org\/10.1016\/j.ijrobp.2008.05.041","relation":{},"ISSN":["0360-3016"],"issn-type":[{"value":"0360-3016","type":"print"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}